Risk of second malignant neoplasms among lymphoma patients with a family history of cancer.

Abstract:

:Radiotherapy and chemotherapy are known risk factors for second cancers after lymphoma. The role of genetic influences, however, remains largely unknown. We assessed risk of second cancers associated with family history of any cancer in 41,181 patients with Hodgkin lymphoma (HL) (n = 7,476), non-Hodgkin lymphoma (NHL) (n = 25,941), or chronic lymphocytic leukemia (CLL) (n = 7,764), using a large population-based database. Family history of cancer was based on a diagnosis of any cancer in 110,862 first-degree relatives. We found increased relative risk (RR) (1.81, 95% confidence interval (CI): 1.04-3.16) of breast cancer among HL patient with positive (vs. negative) family history of cancer. Among CLL patients with positive (vs. negative) family history of cancer, we observed elevated risks of bladder (RR = 3.53, 95% CI: 1.31-9.55) and prostate cancer (RR = 2.15, 95% CI: 1.17-3.94). For NHL patients with positive (vs. negative) family history of cancer, we observed non-significantly increased risk of non-melanoma skin cancer (RR = 1.94, 95% CI: 0.86-4.38) and lung cancer (RR = 1.99, 95% CI: 0.73-5.39). Our observations suggest that genetic factors, as measured by positive family history of cancer, may be influential risk-factors for selected second tumors following lymphoproliferative disorders.

journal_name

Int J Cancer

authors

Landgren O,Pfeiffer RM,Stewart L,Gridley G,Mellemkjaer L,Hemminki K,Goldin LR,Travis LB

doi

10.1002/ijc.22414

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

1099-102

issue

5

eissn

0020-7136

issn

1097-0215

journal_volume

120

pub_type

杂志文章
  • Hand-spinning chrysotile exposure and risk of malignant mesothelioma: A case-control study in Southeastern China.

    abstract::While chrysotile has been commonly used by Chinese textile industry for many years, investigations on the association of chrysotile exposure with risk of mesothelioma in China are scarce. We conducted a case-control study in a county located at Southeastern China, including 46 cases and 230 individually matched contro...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.31077

    authors: Jiang Z,Chen T,Chen J,Ying S,Gao Z,He X,Miao C,Yu M,Feng L,Xia H,Wu W,Chen R,Morinaga K,Lou J,Zhang X

    更新日期:2018-02-01 00:00:00

  • +331G/A variant in the progesterone receptor gene, postmenopausal hormone use and risk of breast cancer.

    abstract::A functional promoter polymorphism in the progesterone receptor (PR) gene previously has been associated with an increased risk of postmenopausal breast cancer. Whether the relationship between genetic variation in PR and risk of breast cancer is modified by postmenopausal hormone (PMH) use is unknown. Thus, we conduc...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24477

    authors: Kotsopoulos J,Tworoger SS,De Vivo I,Hankinson SE,Hunter DJ,Willett WC,Chen WY

    更新日期:2009-10-01 00:00:00

  • Influence of habitual smoking on gastric cancer by histologic subtype.

    abstract::A comparative case-referent study was conducted using data from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC), with the aim of clarifying whether histologic subtypes of gastric cancer exhibit different risk-factor patterns of habitual smoking. Our study comprised 995 histologically...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0215(19990331)81:1<39::aid-ijc8

    authors: Inoue M,Tajima K,Yamamura Y,Hamajima N,Hirose K,Nakamura S,Kodera Y,Kito T,Tominaga S

    更新日期:1999-03-31 00:00:00

  • Cancer registration and healthcare access in West Bank, Palestine: a GIS analysis of childhood cancer, 1998-2007.

    abstract::In low and middle income countries (LMIC), high-quality disease registration is difficult to achieve in the setting of inadequate healthcare infrastructure and political or economical instability. In this article, we explore the potential of geographic information systems (GIS) to add value to the understanding of chi...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25732

    authors: Bailony MR,Hararah MK,Salhab AR,Ghannam I,Abdeen Z,Ghannam J

    更新日期:2011-09-01 00:00:00

  • Brain-derived neurotrophic factor is a potential osteoclast stimulating factor in multiple myeloma.

    abstract::Multiple myeloma (MM) is characterized by accumulation of monoclonal plasma cells in the bone marrow and progression of lytic bone lesions. The mechanisms of enhanced bone resorption in patients with myeloma are not fully defined. We have previously identified the role of brain-derived neurotrophic factor (BDNF) in pr...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.26059

    authors: Sun CY,Chu ZB,She XM,Zhang L,Chen L,Ai LS,Hu Y

    更新日期:2012-02-15 00:00:00

  • Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein.

    abstract::Activity of Janus kinase 2 (JAK2) in the JAK2/STAT5 signaling pathway is critically controlled by suppressor of cytokine signaling-1 (SOCS-1). We have previously shown that SOCS-1 is biallelically mutated in the primary mediastinal B-cell lymphoma (PMBL) cell line MedB-1, resulting in impaired JAK2 degradation and sus...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.21485

    authors: Melzner I,Weniger MA,Bucur AJ,Brüderlein S,Dorsch K,Hasel C,Leithäuser F,Ritz O,Dyer MJ,Barth TF,Möller P

    更新日期:2006-04-15 00:00:00

  • Quantitative proteomics to study a small molecule targeting the loss of von Hippel-Lindau in renal cell carcinomas.

    abstract::Inactivation of the tumor suppressor gene, von Hippel-Lindau (VHL), is known to play an important role in the development of sporadic clear cell renal cell carcinomas (ccRCCs). Even if available targeted therapies for metastatic RCCs (mRCCs) have helped to improve progression-free survival rates, they have no durable ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.30774

    authors: Bouhamdani N,Joy A,Barnett D,Cormier K,Léger D,Chute IC,Lamarre S,Ouellette R,Turcotte S

    更新日期:2017-08-15 00:00:00

  • An eHealth decision-support tool to prioritize referral practices for genetic evaluation of patients with Wilms tumor.

    abstract::Over 10% of children with Wilms tumor (WT) have an underlying cancer predisposition syndrome (CPS). Cognizant of increasing demand for genetic evaluation and limited resources across health care settings, there is an urgent need to rationalize genetic referrals for this population. The McGill Interactive Pediatric Onc...

    journal_title:International journal of cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/ijc.32561

    authors: Cullinan N,Villani A,Mourad S,Somers GR,Reichman L,van Engelen K,Stephens D,Weksberg R,Foulkes WD,Malkin D,Grant R,Goudie C

    更新日期:2020-02-15 00:00:00

  • Residential and occupational exposure to 50-Hz magnetic fields and brain tumours in Norway: a population-based study.

    abstract::Our case-control study was conducted to investigate whether residential and occupational exposure to magnetic fields increased the risk for brain tumours in adults. Data from an occupational exposure matrix was also evaluated. The study population in this nested case-control study was made up of subjects aged 16 years...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.20845

    authors: Klaeboe L,Blaasaas KG,Haldorsen T,Tynes T

    更新日期:2005-05-20 00:00:00

  • Sister chromatid exchange in lymphoma line and lymphoblastoid cell lines before and after heterotransplantation into nude mice.

    abstract::The sister chromatid exchange (SCE) rates of cell lines derived from patients with different malignant and premalignant disease were studied before and after intracerebral inoculation into nude mice and were compared to the SCE frequencies of cell lines from healthy controls. Lymphoma lines characterized by chromosoma...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910280408

    authors: Fonatsch C,Kirchner HH,Schaadt M,Günzel M,Diehl V

    更新日期:1981-10-15 00:00:00

  • TP53 mutation and survival in aggressive B cell lymphoma.

    abstract::TP53 is mutated in 20-25% of aggressive B-cell lymphoma (B-NHL). To date, no studies have addressed the impact of TP53 mutations in prospective clinical trial cohorts. To evaluate the impact of TP53 mutation to current risk models in aggressive B-NHL, we investigated TP53 gene mutations within the RICOVER-60 trial. Of...

    journal_title:International journal of cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/ijc.30838

    authors: Zenz T,Kreuz M,Fuge M,Klapper W,Horn H,Staiger AM,Winter D,Helfrich H,Huellein J,Hansmann ML,Stein H,Feller A,Möller P,Schmitz N,Trümper L,Loeffler M,Siebert R,Rosenwald A,Ott G,Pfreundschuh M,Stilgenbauer S,Ger

    更新日期:2017-10-01 00:00:00

  • Erionite and asbestos differently cause transformation of human mesothelial cells.

    abstract::Malignant mesothelioma (MM) is an aggressive tumor associated with environmental or occupational exposure to asbestos fibers. Erionite is a fibrous zeolite, morphologically similar to asbestos and it is assumed to be even more carcinogenic. Onset and progression of MM has been suggested as the result of the cooperatio...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.22687

    authors: Bertino P,Marconi A,Palumbo L,Bruni BM,Barbone D,Germano S,Dogan AU,Tassi GF,Porta C,Mutti L,Gaudino G

    更新日期:2007-07-01 00:00:00

  • Telomere homolog oligonucleotides induce apoptosis in malignant but not in normal lymphoid cells: mechanism and therapeutic potential.

    abstract::Human B- or T-cell lymphoma lines and primary murine lymphomas were treated with DNA oligonucleotides homologous to the telomere (TTAGGG repeat; "T-oligo"), either alone or in combination with standard, widely-used anticancer chemotherapeutic agents. T-oligo induces cell cycle arrest and apoptosis in cultured human or...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.23946

    authors: Longe HO,Romesser PB,Rankin AM,Faller DV,Eller MS,Gilchrest BA,Denis GV

    更新日期:2009-01-15 00:00:00

  • Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: evidence for a protective effect of soy in nonsmokers.

    abstract::The factors associated with risk of lung cancer among nonsmokers have not been fully elucidated, but dietary factors have consistently been shown to play a role. Chinese women are unique in having a high incidence of lung cancer despite a low smoking prevalence. This population is also known to have a high intake of s...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.1615

    authors: Seow A,Poh WT,Teh M,Eng P,Wang YT,Tan WC,Chia KS,Yu MC,Lee HP

    更新日期:2002-01-20 00:00:00

  • Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer.

    abstract::In a previous study, human ZNF312b was identified as a cell proliferation-associated oncogene via the K-ras/extracellular signal-regulated kinase cascade in gastric cancer. However, the mechanism concerning its transcriptional activation remains unknown. Here, we show that DNA methylation and histone acetylation of th...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25871

    authors: Song IS,Ha GH,Kim JM,Jeong SY,Lee HC,Kim YS,Kim YJ,Kwon TK,Kim NS

    更新日期:2011-11-01 00:00:00

  • Delayed primary excision with subsequent modification of radiotherapy dose for intermediate-risk rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.

    abstract::The majority of intermediate-risk rhabdomyosarcoma (RMS) patients have gross residual disease (Group III) after their first operative procedure. It is currently not known if local control rates can be maintained when, following induction chemotherapy, the radiation therapy (RT) dose is decreased after a delayed primar...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.29351

    authors: Rodeberg DA,Wharam MD,Lyden ER,Stoner JA,Brown K,Wolden SL,Paidas CN,Donaldson SS,Hawkins DS,Spunt SL,Arndt CA

    更新日期:2015-07-01 00:00:00

  • Pooled analysis of 3 European case-control studies of ovarian cancer: II. Age at menarche and at menopause.

    abstract::The role of age at menarche and at menopause on epithelial ovarian cancer risk was re-assessed in a combined analysis of 3 hospital-based case-control studies conducted in Italy, the United Kingdom and Greece, which produced a total of 1,140 cases and 2,724 controls. In the overall dataset, there was no evidence of an...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910490111

    authors: Franceschi S,La Vecchia C,Booth M,Tzonou A,Negri E,Parazzini F,Trichopoulos D,Beral V

    更新日期:1991-08-19 00:00:00

  • Transglutaminase 3 as a prognostic biomarker in esophageal cancer revealed by proteomics.

    abstract::To develop a prognostic biomarker for esophageal squamous cell carcinoma (ESCC), we examined the proteomic profile of ESCC using two-dimensional difference gel electrophoresis (2D-DIGE), and identified proteins associated with prognosis by mass spectrometry. The prognostic performance of the identified proteins was ex...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.24194

    authors: Uemura N,Nakanishi Y,Kato H,Saito S,Nagino M,Hirohashi S,Kondo T

    更新日期:2009-05-01 00:00:00

  • TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.

    abstract::Malignant gliomas recur even after extensive surgery and chemo-radiotherapy. Although a relatively novel chemotherapeutic agent, temozolomide (TMZ), has demonstrated promising activity against gliomas, the effects last only a few months and drug resistance develops thereafter in many cases. It has been acknowledged th...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25985

    authors: Zhuang D,Liu Y,Mao Y,Gao L,Zhang H,Luan S,Huang F,Li Q

    更新日期:2012-01-15 00:00:00

  • DNA ploidy and clonal selection in ras + myc-induced mouse prostate cancer.

    abstract::An important goal in prostate cancer research is to define specific molecular and cellular alterations that are associated with malignant progression. The mouse prostate reconstitution model is a relevant and useful system as it allows the study of early events in cancer progression under conditions where oncogene-ini...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910600321

    authors: Greene DR,Taylor SR,Aihara M,Yoshida K,Egawa S,Park SH,Timme TL,Yang G,Scardino PT,Thompson TC

    更新日期:1995-01-27 00:00:00

  • Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia.

    abstract::Common genetic variations in genes involved in DNA repair or response to genotoxic stress may influence both cancer susceptibility and treatment response individually or interactively. However, in acute myeloid leukemia (AML), the relevance of these genetic variations remains to be fully established. In this study, we...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25318

    authors: Shi JY,Ren ZH,Jiao B,Xiao R,Yun HY,Chen B,Zhao WL,Zhu Q,Chen Z,Chen SJ

    更新日期:2011-01-01 00:00:00

  • Cancer survival is dependent on season of diagnosis and sunlight exposure.

    abstract::Sunlight is essential for the production of vitamin D in the body. Evidence exists to suggest that vitamin D metabolites may have a role in tumor growth suppression. In this large study, involving over a million cancer patients from the United Kingdom, we have analyzed the role of season of diagnosis and sunlight expo...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.22052

    authors: Lim HS,Roychoudhuri R,Peto J,Schwartz G,Baade P,Møller H

    更新日期:2006-10-01 00:00:00

  • The decline in the incidence of stomach cancer in Sweden 1960-1984: a birth cohort phenomenon.

    abstract::Trends in the incidence of stomach cancer among 52,604 patients notified to the National Swedish Cancer Registry in 1960 through 1984 were analysed. Age-standardized incidence rates declined throughout the period, from 47.1 to 24.6 per 10(5) in males and from 23.8 to 12.7 per 10(5) in females. Among males the decline ...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910470405

    authors: Hansson LE,Bergström R,Sparén P,Adami HO

    更新日期:1991-02-20 00:00:00

  • Effects of the exercise-inducible myokine irisin on malignant and non-malignant breast epithelial cell behavior in vitro.

    abstract::Exercise has been shown to reduce risk and improve prognosis of several types of cancers. Irisin is a myokine linked to exercise and lean body mass, which is thought to favorably alter metabolism systemically, potentially providing benefit for metabolic disease (including cancer). We evaluated the effects of various c...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.29142

    authors: Gannon NP,Vaughan RA,Garcia-Smith R,Bisoffi M,Trujillo KA

    更新日期:2015-02-15 00:00:00

  • Plasma decorin predicts the presence of esophageal squamous cell carcinoma.

    abstract::Using a microarray technique, we found decorin to be underexpressed, but osteopontin (OPN) to be overexpressed, in esophageal squamous cell carcinoma (ESCC). This study aims to examine whether plasma decorin and OPN plus personal substances use (tobacco, alcohol and areca) can serve as suitable clinical markers to pre...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.25239

    authors: Wu IC,Wu DC,Huang CC,Lin HS,Chen YK,Tsai HJ,Lu CY,Chou SH,Chou YP,Li LH,Tai SY,Wu MT

    更新日期:2010-11-01 00:00:00

  • Analysis of normal neoplastic human tissues for the tumor-associated protein p97.

    abstract::We have used immunoprecipitation to test tumor biopsies and normal adult and fetal human tissues for p97, a tumor-associated protein. Five of nine melanoma biopsies contained p97 in low to very high levels. Three of seven non-melanoma tumors contained p97, but in smaller amounts. No p97 was detected in any of the norm...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910270204

    authors: Woodbury RG,Brown JP,Loop SM,Hellström KE,Hellström I

    更新日期:1981-02-15 00:00:00

  • Long-term risk of colorectal cancer after screen-detected adenoma: Experiences from a Danish gFOBT-positive screening cohort.

    abstract::Fecal occult blood test (FOBT) screening for colorectal cancer (CRC) is implemented in several countries. Approximately half of all FOBT-positive persons have screen-detected adenomas. Despite removal of these, patients with large/multiple adenomas have increased risk of later developing new advanced adenomas and CRC....

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.32850

    authors: Bjerrum A,Lindebjerg J,Andersen O,Fischer A,Lynge E

    更新日期:2020-08-15 00:00:00

  • Cell surface antigens of human trophoblast and choriocarcinoma defined by monoclonal antibodies.

    abstract::Six distinct cell surface antigens of human trophoblast and choriocarcinoma were defined with MAbs. The distribution of the antigens was determined by MHA assays on 150 tumor cell lines and normal cell cultures and by immunofluorescence tests with a wide range of normal adult and fetal tissues and a tumor panel. Antig...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910350409

    authors: Rettig WJ,Cordon-Cardo C,Koulos JP,Lewis JL Jr,Oettgen HF,Old LJ

    更新日期:1985-04-15 00:00:00

  • Risk of cutaneous melanoma associated with pigmentation characteristics and freckling: systematic overview of 10 case-control studies. The International Melanoma Analysis Group (IMAGE).

    abstract::Using individual subject data from 10 case-control studies, comprising over 3000 cases and almost 4000 controls, we have estimated the relative risk of melanoma associated with aspects of complexion, namely, hair, eye and skin colour and freckling in adulthood, and have examined the relationships between these factors...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.2910620402

    authors: Bliss JM,Ford D,Swerdlow AJ,Armstrong BK,Cristofolini M,Elwood JM,Green A,Holly EA,Mack T,MacKie RM

    更新日期:1995-08-09 00:00:00

  • Italian Mediterranean Index and risk of colorectal cancer in the Italian section of the EPIC cohort.

    abstract::Colorectal cancer is among the commonest cancers worldwide. Dietary factors have been linked to colorectal cancer risk, however, few studies have evaluated the relationship between a priori dietary patterns and colorectal cancer risk. We evaluated the effect of adherence to a Mediterranean dietary pattern, as measured...

    journal_title:International journal of cancer

    pub_type: 杂志文章

    doi:10.1002/ijc.27740

    authors: Agnoli C,Grioni S,Sieri S,Palli D,Masala G,Sacerdote C,Vineis P,Tumino R,Giurdanella MC,Pala V,Berrino F,Mattiello A,Panico S,Krogh V

    更新日期:2013-03-15 00:00:00