[Laparoscopic-assisted versus open surgery for colorectal cancer: postoperative morbidity in a single center randomized trial].

Abstract:

AIM:The primary objective of the study was to compare the effect of laparoscopic-assisted (LPS) versus open surgery (LPT) for colorectal cancer on postoperative morbidity. The secondary objectives were to evaluate immune response and intestinal wall oxygen perfusion. METHODS:A total of 610 patients with colorectal cancer were randomly assigned to receive colon resection by either LPS (n=306) or LPT (n=304). Four surgical staff members not involved in the study recorded postoperative complications up to 30 days after the operation. Immune response was evaluated by measuring lymphocytic proliferation after challenge with Candida albicans and phytohemoagglutinin before, at 3 and 15 days after the operation. Intestinal wall oxygen perfusion was continuously monitored using a probe. RESULTS:The conversion rate was 4.6% in the LPS group. Morbidity was 18.6% in the LPS group and 34.5% in the LPT group (P<0.0005). Infections developed in 9.1% of LPS-treated patients and in 20.2% of LPT-treated patients (P<0.0005). The mean length of stay was 9.7+/-2.6 days in the LPS group and 12.2+/-4.2 days in the LPT group (P<0.0001). In both groups lymphocytic proliferation was low at 3 days postoperative but returned to normal range at 15 days only in the LPS group. Interoperative intestinal oxygen perfusion values were higher in the LPS group. CONCLUSIONS:Laparoscopic colorectal surgery reduced both postoperative morbidity and length of stay. Lymphocytic proliferation and intestinal wall oxygen perfusion were higher in patients who underwent laparoscopic-assisted surgery.

journal_name

Minerva Chir

journal_title

Minerva chirurgica

authors

Frasson M,Braga M,Vignali A,Zuliani W,Gruarin P,Dellabona P,Di Carlo V

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

283-92

issue

4

eissn

0026-4733

issn

1827-1626

journal_volume

61

pub_type

杂志文章,随机对照试验
  • [The clinical aspects of 49 cases of early gastric cancer].

    abstract::Forty-nine consecutive patients with early gastric cancer (EGC), observed from January 1978 to December 1992 in the Surgery Department of our Institute, were included in a retrospective study. The EGC prevalence in the overall cases of gastric cancer was 11%. This frequency was 8% in the period 1978-1985 and 15% in th...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Leo S,Taveri R,Campanella GA,Lorusso D,Pezzolla F,Bonfiglio C

    更新日期:1994-12-01 00:00:00

  • [Laparoscopic harvest of the jejunal free flap for cervical esophageal reconstruction].

    abstract::The jejunal free flap is a standard technique in the reconstruction of hypopharyngeal and cervical esophageal defects. Conventional harvesting of the jejunal segment is performed with midline open laparotomy, which is associated with complications including prolonged ileus, abdominal pain, wound infection or dehiscenc...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Bardone M,Alessiani M,Zonta S,Longoni M,Faillace G,Benazzo M,Occhini A,Dionigi P

    更新日期:2006-04-01 00:00:00

  • [The role of surgical therapy for esophageal microcytoma. Experience of there clinical cases and results analysis].

    abstract::Small cell carcinoma of the esophagus is a rare tumor. It was described for the first time in 1952 by McKeown and 200 cases have been reported till now. Because of its similarity with small cell carcinoma of the lung, the treatment of this tumor is controversial. In our Institute we treated three patients with small c...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Brega-Massone PP,Conti B,Lequaglie C,Ferro F,Cataldo I

    更新日期:2003-08-01 00:00:00

  • [Influence of ischemia time on the long-term survival of kidney re-transplants].

    abstract::The influence of warm and cold ischemia times on the long term survival of subsequent renal allografts has been evaluated. The retrospective study has involved 77 patients who in the year period 1966-1977 were submitted to 86 subsequent renal allografts at the Department of Surgery of the Addenbrooke's Hospital-Cambri...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Marni A,McMaster P,Grassi G,Evans DB,Calne RY

    更新日期:1981-05-31 00:00:00

  • [Double-blind evaluation of the effectiveness of cimetidine in the arrest of hemorrhages due to gastroduodenal peptic lesions].

    abstract::40 patients with an endoscopic diagnosis of bleeding gastric or duodenal lesions have been examined in a double blind study. The haemorrhages were subdivided into slight and serious on the basis of objective parameters. Cimetidine (1.2 g/die i.v.) or placebo in a preparation indistinguishable from the drug were admini...

    journal_title:Minerva chirurgica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Olivero S,Foco A,Garbarini A,Sigaudo G,Vottero G,Checchini P,Benvenuti C,Enrichens F

    更新日期:1981-10-15 00:00:00

  • [Use of defibrotide in the treatment of acute superficial thrombophlebitis of the legs].

    abstract::The efficacy of defibrotide in the treatment of acute thrombophlebitis of the legs has been investigated in 140 patients, randomized into two groups. All patients received defibrotide either alone or as an addition to conventional therapies. Two different schemes of administration were selected and carried out in each...

    journal_title:Minerva chirurgica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Seccia M,Bortolotti P,Bellomini MG,Buccianti P,Chiarugi M,Cavina E

    更新日期:1989-05-15 00:00:00

  • [The reappearance of gastrointestinal tuberculosis in general surgery].

    abstract::Gastro-intestinal tuberculosis (TB) continues to give rise to diagnostic and therapeutic challenges. Its increasing incidence and multiple and non-specificity of symptoms and signs require special attention to establish a prompt diagnosis and not to delay treatment. The authors describe on case of colonic TB presentin...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: D'Urbano C,Thodas A,Assisi F,Fuertes Guiró F,Perelli Ercolini M

    更新日期:1995-10-01 00:00:00

  • [Cancer of the gastric stump. Our experience].

    abstract::The authors discuss their experience of six cases of cancer of the gastric stump observed by them in the period from 1988 to 1992 inclusive. All the patients were operated; five total gastrectomies and a gastric re-resection were effected. In association also the spleen was removed in four patients, in one of them a h...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Nardi M,D'Amico G,Basti M,Pitrelli N,Casciani E,Cellini G

    更新日期:1994-04-01 00:00:00

  • Cystic pneumatosis of the colon after liver transplantation.

    abstract::Cystic pneumatosis (CP) is an uncommon but significant condition in adults in which gas is found in a linear or cystic form in the submucosa or the subserosa of the bowel wall. The diagnosis was made by conventional X-ray and confirmed by abdominal computed tomography. Benign pneumoperitoneum due to CP should be consi...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Halkic S,Zeini S,Mosimann F,Gillet M

    更新日期:2003-06-01 00:00:00

  • Clinical observation of laser ablation combined with chemotherapy in postoperative colorectal cancers with liver metastasis.

    abstract:BACKGROUND:This study is to evaluate the efficacy and adverse reaction of a combination therapy of chemotherapy and laser thermal ablation (LTA) on liver metastases from colorectal cancer. METHODS:Eighty-five cases colorectal cancer liver metastases were assigned to the treatment group (43 cases) and to the control gr...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:10.23736/S0026-4733.16.07204-7

    authors: Lichun D,Dazhong Z,Wei Sheng S,Xiongwei L,Huaming S,Lei X,Jie Z,Xiangming C

    更新日期:2017-02-01 00:00:00

  • [The SITAR Project. A new approach to diagnosis and surgical indication in arteriopathic patients].

    abstract::The extreme variations with which atherosclerotic disease presents as regards progression index, arterial bed localization frequency, malignity and invasiveness in different ages and often as regards different anatomopathological aspects characterizing the formation and course of the primary lesion, mean that there ar...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Biasi G,Viola G,Vaccari E

    更新日期:1977-04-15 00:00:00

  • Myocardial revascularization in porcelain aorta: impact of age on conduct of surgery.

    abstract::Myocardial revascularization among patients with porcelain aorta is a real dilemma regarding bypass technique, choice of conduit and site of proximal anastomosis. The experience reported here is about two cases of patients (aged 28 and 73 years) with porcelain aorta. Both patients had successful myocardial revasculari...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Darwazah KA,Abu Sham'a RA,Hanbali B

    更新日期:2007-12-01 00:00:00

  • [Spontaneous cholecysto-cutaneous fistula].

    abstract::A recently observed personal case of spontaneous cholecystospontaneous fistula is reported. Factors leading to the relative infrequency of this form in recent years are described, and its rarity is demonstrated by the fact that the case reported was the first to be noted in about 1000 operations on the bile ducts. A b...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Sturniolo G,Carditello A,Cavallaro G

    更新日期:1981-02-15 00:00:00

  • Management of ductal carcinoma in situ in the modern era.

    abstract::Ductal carcinoma in situ (DCIS) has been the subject of much controversy since the advent of population based breast screening programs. An increasing number of asymptomatic women are being diagnosed with this condition and there is uncertainty over the best treatment algorithm for this condition if treatment is to be...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章,评审

    doi:10.23736/S0026-4733.18.07729-5

    authors: Khan A,Dumitru D,Catanuto G,Rocco N,Nava MB,Benson J

    更新日期:2018-06-01 00:00:00

  • The Video-Consulting Emergency protocol: a proposition from the World Society of Emergency Surgery members for the initial management of non-traumatic acute abdomen.

    abstract:BACKGROUND:Our aim is to propose the Video-Consulting Emergency (VCE) protocol as a tool to improve the decision-making process between an on-site emergency physician and a remote acute care surgeon using a smartphone, the FaceTime application, and the Acute Abdominal Decision Making (AADM®) model proposed by World Soc...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:10.23736/S0026-4733.18.07963-4

    authors: De Simone B,Ansaloni L,Sartelli M,Coccolini F,Napoli JA,Catena F

    更新日期:2019-06-01 00:00:00

  • [Revascularization syndrome in traumatic vascular lesions of the limbs].

    abstract::The authors report a case of severe revascularization syndrome which occurred following traumatic vascular lesion to a lower limb. They focus attention on the mechanisms which make this syndrome more frequent and more severe in traumatic lesions as opposed to that observed following acute arterial obstruction secondar...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: De Blasis G,Sedici A,D'Elia M,Palladini I,Scipioni L

    更新日期:1994-09-01 00:00:00

  • [The use of the BAR-Valtrac-type pressure stapler in surgery of the large intestine].

    abstract::A total of 148 patients underwent colon resection between June 1993 and November 1994 at the General Surgery Division of Busto Arsizio Hospital; anastomosis was performed using BAR Valtrac in 58 patients (39%), namely 28 males and 30 women with a mean age of 66.3 years. Surgery was elective in 90% of cases and in 84% ...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Salatino G,Massazza C,Armiraglio L,Branchini L,Berardi V,Di Lernia S,Maggioni D,Scandroglio I,Tosi F,Pugliese R

    更新日期:1997-12-01 00:00:00

  • Innovative technology for colostomy irrigation: assessing the impact on patients.

    abstract:AIM:The main purpose of the trial was to evaluate the opinions expressed by a sample of subjects with permanent colostomy, as a result of the use of a new device designed for the execution of transtomal intestinal irrigation; their feedback was analyzed in relation to the concept of Quality of Life. METHODS:The device...

    journal_title:Minerva chirurgica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Pace S,Manuini F,Maculotti D

    更新日期:2015-10-01 00:00:00

  • [Surgery in the cirrhotic patient. Prognosis and risk factors].

    abstract::Patients with cirrhosis have reduced life expectancy. Surgery is often associated with clinical decompensation in this group of patients. The purpose of this paper is to study the surgical risk in cirrhotic patients undergoing nonderivative operations. Unfortunately, most of the studies in the literature about this pr...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章,评审

    doi:

    authors: Pisani Ceretti A,Cordovana A,Pinto A,Spina GP

    更新日期:2000-11-01 00:00:00

  • [Criteria for suspected lithiasis of the common bile duct].

    abstract::Although the common bile duct is now accessed using a coelioscopic approach by an increasing number of surgical equipes, the problems related to the diagnostic iter of lithiasis of the common bile duct and the need to obtain a correct preoperative diagnosis, in order to select the most appropriate form of therapy, are...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章,评审

    doi:

    authors: Moscatiello P,Chollet JM

    更新日期:1995-03-01 00:00:00

  • [Cholangiography in laparoscopic surgery].

    abstract::Cholangiography carried out in laparoscopic surgery is a diagnostic exam considered by many authors to be very important for the anatomy and the research pre-existent pathologies of the biliary tree. Such are the effective advantages that many Schools suggest it be carried out any case as the risks, the costs and the ...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Pitrelli N,DiBartolomeo N,Grossi S

    更新日期:1996-04-01 00:00:00

  • [Clinical efficacy of nimesulide compared to diclofenac sodium in the prevention and treatment of postoperative pain-inflammation symptomatology].

    abstract::In a double blind, controlled clinical study, 40 patients, 20 of whom were subjected to mastectomy or quadrantectomy and 20 to inguinal hernioplasty, were randomly assigned to two treatment groups of 20 subjects each, balanced by type of operation. Treatment lasted 3 days and involved the administration of 3 supposito...

    journal_title:Minerva chirurgica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Stefanoni G,Saccomanno F,Scaricabarozzi I,Volontieri G,Persiani L,Boselli A,Beretta P,Giroda M

    更新日期:1990-12-01 00:00:00

  • [The role of surgery in the management of diffuse (N3) lung cancer].

    abstract::The aim of the paper is to give a contribution to the understanding of the role of surgery in patients with N3 lung cancer. The A. describe their results on 32 patients with N3 lung cancer operated on mediastinectomy; histological examination of the specimens showed 27 squamous cell carcinomas and 5 adenocarcinomas. T...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Politi L,Bresadola V,Ferrandu T,De Anna D

    更新日期:1995-12-01 00:00:00

  • [NMR cholangiography in the diagnostic algorithm of candidates to video laparocholecystectomy].

    abstract:BACKGROUND:High resolution magnetic resonance cholangiopancreatography (MRCP) is a non invasive imaging modality for depicting the pancreatobiliary tree. It can demonstrate dilation, stenosis and intraductal filling defects of both the biliary and the pancreatic duct. The imaging quality of high resolution MRCP is exce...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Puglisi F,Magialetti A,Carriero A,Capuano F,De Fazio M,Verzillo F,Martines G,Simone M

    更新日期:2000-09-01 00:00:00

  • [Male varicocele. Analysis of the incidence of varicocele in a population of 18,800 young men].

    abstract::The authors evaluate the incidence of varicocele after having examined 18,800 healthy white men members of the Italian Army Corps born in 1966 and visited in 1985. They found a varicocele in 775 patients (4.12%), in 5 was present bilaterally, and in 770 in the left side. In 45 patients the surgical treatment was alrea...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章,评审

    doi:

    authors: Pricolo R,Croce P,Salvatori P

    更新日期:1990-03-31 00:00:00

  • [Postoperative complications in the Billroth I gastrectomy].

    abstract::A series of 234 patients who underwent Billroth I gastric resection for gastric and duodenal ulcerous lesions is reported. Special attention is paid to the immediate postoperative complications whose incidence was 5.5%. Particularly serious is the dehiscence of gastroduodenal anastomosis which requires emergency recon...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Petrassi A,Petrolo F,Gradia B

    更新日期:1979-02-15 00:00:00

  • [Functional evaluation of gastric and jejunal transplant after esophagectomy].

    abstract::Increased survival rates after esophagectomy for cancer and the significant development of forms of therapy alternate to surgical treatment, today compel surgeons to devote far more attention to the methods will pursue in reconstructing the alimentary tract after removal of the esophagus. Nine patients with esophago-g...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Pandolfo N,Spigno L,Guiddo G,Tronfi G,Villavecchia G,Mattioli FP

    更新日期:1991-04-15 00:00:00

  • [Wounds of the heart. Diagnostic study and clinical case reports].

    abstract::Two cases of cardiac wounds in association with acute anaemia and acute cardiac tamponade respectively are presented. The statistical and, more particularly, the diagnostic factors involved are discussed. Stress is laid on the measurement of CVP along with pericardiocentesis. Correct interpretation of the data furnish...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:

    authors: Vallefuoco V,Rispoli G

    更新日期:1978-11-15 00:00:00

  • The Gauze technique: a simple method of dissection in laparoscopic inguinal hernia repair.

    abstract:BACKGROUND:Hernia repair is one of the most frequent operation in general surgery. The aim of this is study is to present a new preperitoneal atraumatic dissection of peritoneal flap during laparoscopic transabdominal preperitoneal inguinal hernia repair. METHODS:From January 2019 to December 2019, 30 patients (19 mal...

    journal_title:Minerva chirurgica

    pub_type: 杂志文章

    doi:10.23736/S0026-4733.20.08335-2

    authors: Coratti F,Trafeli M,Barbato G,Maggioni C,Manetti A,Cianchi F

    更新日期:2020-12-01 00:00:00

  • [Traditional cutaneous suture and synthesis with Fasterzip. Comparative esthetic results].

    abstract::A group of 20 patients underwent plastic surgery for inguinal hernia. In 10 cases the incision was sutured using a traditional technique, whereas in 10 cases the wound was joined using Fasterzip. The cosmetic appearance of the wound in the two groups was compared at 8, 30, 60 and 90 days after surgery. It was found th...

    journal_title:Minerva chirurgica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Boltri M

    更新日期:1998-05-01 00:00:00