Abstract:
AIM:To evaluate the effects of bioactive glass S53P4 versus calcium hydroxide when used as dressings in contra-lateral human premolars infected with Enterococcus faecalis ATCC 29212. METHODOLOGY:Pairs of contra-lateral premolar teeth plus single control premolars were obtained from 23 individuals aged 10-26 years undergoing orthodontic treatment. Root canals of teeth with fully formed apices (nine contra-lateral pairs, seven controls) were instrumented using a size 60 FlexoFiles 2 mm short of canal length. Canals with open apices (six contra-lateral pairs, four controls) were circumferentially instrumented using a FlexoFile. Root canals were rinsed with 1% sodium hypochlorite and 10% citric acid. Teeth were then suspended in tryptic soy broth (TSB) and autoclaved. Positive controls and study teeth were infected with E. faecalis ATCC 29212 for 2 weeks in TSB, while negative controls were kept in sterile TSB. Subsequently, contra-lateral premolars were dressed with bioactive glass S53P4 (BAG) or calcium hydroxide suspensions for 10 days. Dentine samples were obtained from teeth with fully formed apices using ISO-size 70, 80 and 90 FlexoFiles to working length and cultured. Teeth with open apices were fixed, fractured and examined using scanning electron microscopy (SEM). RESULTS:Calcium hydroxide had a strong antibacterial effect and was significantly more effective than BAG in preventing residual bacterial growth (P < 0.01). SEM analysis revealed apparent substance-specific modes of action. CONCLUSIONS:Calcium hydroxide was an effective disinfectant in human teeth.
journal_name
Int Endod Jjournal_title
International endodontic journalauthors
Zehnder M,Luder HU,Schätzle M,Kerosuo E,Waltimo Tdoi
10.1111/j.1365-2591.2006.01173.xsubject
Has Abstractpub_date
2006-12-01 00:00:00pages
952-8issue
12eissn
0143-2885issn
1365-2591pii
IEJ1173journal_volume
39pub_type
杂志文章,随机对照试验abstract:AIM:To analyse torque and force generated whilst shaping curved canals using rotary instruments. METHODOLOGY:A specially designed computer-controlled testing platform was used to record events during the shaping of straight and curved canals in plastic blocks and in extracted human teeth using ProFile.04 instruments. ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.0143-2885.2001.00494.x
更新日期:2002-04-01 00:00:00
abstract:AIM:To investigate the use of a zinc oxide/zinc sulphate-based cement (Coltosol(®) F, Coltène Whaledent, Cuyahoga Falls, OH, USA) as a temporary filling material during multiple-visit root canal treatments and the occurrence of cracks within the filling material or the tooth. METHODOLOGY:Root canals of one hundred and...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12280
更新日期:2015-01-01 00:00:00
abstract:AIM:To analyse the influence of exposure of mineral trioxide aggregate (MTA) with and without calcium chloride (CaCl2 ) to phosphate-buffered saline (PBS) on the push-out bond strength, over different experimental periods. METHODOLOGY:One hundred and twenty dentine discs with standardized cavities were filled with MTA...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12168
更新日期:2014-05-01 00:00:00
abstract:AIMS:(i) To compare the prevalence of extrusion of root filling material when placed using different root filling techniques, with or without customization of the master gutta-percha (GP) cone; and (ii) to investigate the effects of some factors influencing root filling extrusion and presence of voids. METHODOLOGY:A t...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2005.01005.x
更新日期:2005-09-01 00:00:00
abstract:AIM:This study evaluated the effects of different root canal sealers on the bond strength of a fibreglass post cemented with self-adhesive resin cements. METHODOLOGY:The root canals of 50 extracted maxillary single-rooted canine teeth were prepared with the crown-down technique and randomly divided into five groups ac...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2010.01831.x
更新日期:2011-04-01 00:00:00
abstract:AIM:To evaluate the influence of thermomechanical compaction (Tagger's hybrid technique - THT) on the push-out strength of several root filling materials to root dentine. METHODOLOGY:Root canals of eighty roots in human canines were prepared with the ProTaper system and filled with one of the following materials, usin...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2012.02039.x
更新日期:2012-09-01 00:00:00
abstract:AIM:To investigate the molecular mechanisms of nitric oxide (NO)-induced cytotoxic effect in human gingival fibroblast (HGF) cells. METHODOLOGY:After sodium nitroprusside (SNP), as NO donor, was treated to HGF, viability was measured by MTT assay and apoptosis was determined by TUNEL and DNA fragmentation assay. Mitoc...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12314
更新日期:2015-03-01 00:00:00
abstract:AIM:To evaluate the effect of a glide path on the amount of apically extruded debris during canal preparation using single-file systems in curved canals. METHODOLOGY:Ninety extracted mandibular molar teeth were randomly assigned to six groups (n = 15 for each group) for canal instrumentation. Endodontic access cavitie...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12484
更新日期:2016-06-01 00:00:00
abstract:AIM:To report on a novel method to instrument a dilacerated double-curved mandibular premolar. SUMMARY:A 45-year-old female was referred suffering from diffuse pain emanating from the mandibular right quadrant. The second premolar (tooth 45) was diagnosed with symptomatic irreversible pulpitis. The radiographic examin...
journal_title:International endodontic journal
pub_type:
doi:10.1111/iej.12610
更新日期:2017-02-01 00:00:00
abstract:AIM:To evaluate the neurotoxic effects of two endodontic sealers, AH-26 and Roth 801, on firing excitability and action potential configuration of F1 neural cells in the suboesophageal ganglia of Helix aspersa. METHODOLOGY:A conventional intracellular current clamp technique was used to study the blocking effects of A...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2003.00751.x
更新日期:2003-12-01 00:00:00
abstract:AIM:To compare dentinal microcrack formation whilst using Ni-Ti hand K-files, ProTaper hand and rotary files and the WaveOne reciprocating file. METHODOLOGY:One hundred and fifty mandibular first molars were selected. Thirty teeth were left unprepared and served as controls, and the remaining 120 teeth were divided in...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12197
更新日期:2014-07-01 00:00:00
abstract:AIM:To compare periapical health using samples from prehistoric and historic periods until the present day, and to emphasize the major risk indicators for apical periodontitis (AP). METHODOLOGY:A comparative survey to assess periapical health was performed on five samples (525 individuals) drawn from different periods...
journal_title:International endodontic journal
pub_type: 历史文章,杂志文章
doi:10.1111/j.1365-2591.2005.00905.x
更新日期:2005-05-01 00:00:00
abstract:AIM:To determine the pain experienced by patients during root canal treatment and to correlate with age and gender, pulpal diagnosis, previous periapical status, dental characteristics and length of treatment. METHODOLOGY:One hundred and seventy-six patients (68 men and 108 women), with ages ranged from 6 to 83 years,...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2009.01562.x
更新日期:2009-07-01 00:00:00
abstract:AIM:To determine whether nisin, a bacteriocin, would be effective at killing Enterococcus faecalis and Streptococcus gordonii cells in solution and within the root canal system. METHODOLOGY:Bacterial isolates of E. faecalis and S. gordonii were grown from glycerol stocks in closed tubes containing BHY broth at 37 degr...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2004.00846.x
更新日期:2004-10-01 00:00:00
abstract:AIM:The apical sealing ability of three different endodontic sealers was evaluated in extracted teeth using dye penetration. METHODOLOGY:The root canals of 99 extracted human maxillary central incisors were prepared sequentially 2 mm beyond the apical foramen with a size 55 Nitiflex file. The teeth were divided into t...
journal_title:International endodontic journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2591.2000.00247.x
更新日期:2000-01-01 00:00:00
abstract::An in-vitro investigation was performed to assess the extent of apical microleakage in simulated canals in clear resin blocks. Four different methods of producing dye penetration were employed: passive dye penetration alone, centrifugation alone, vacuum plus passive dye penetration, and increased pressure plus passive...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1996.tb01362.x
更新日期:1996-05-01 00:00:00
abstract:AIM:To analyse responses from dental practitioners (DPs) on how secure they felt as a newly graduated dentist, level of confidence or self-efficacy when performing root canal treatment (RCT), and if undergraduate (UG) education in Endodontics adequately met their needs in a dental practice. METHODOLOGY:An electronic q...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13455
更新日期:2020-11-30 00:00:00
abstract:AIM:The aim of this study was to compare in vitro bacterial and dye leakage tests, commonly used to determine the seal of root canal fillings. METHODOLOGY:Ninety-six single-rooted teeth had their crowns removed at the cemento-enamel junction and their roots instrumented to ISO size 60 within 1 mm of the apex. Three gr...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.1999.00235.x
更新日期:1999-09-01 00:00:00
abstract:AIM:To investigate the cytotoxicity of a modified salt solution (MSS) and evaluate the antimicrobial properties of MSS on in vitro biofilm models. METHODOLOGY:In a metabolic assay, fibroblasts derived from periodontal ligaments (PDL) of human extracted teeth were cultured and challenged with MSS or controls. Then, in ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12294
更新日期:2015-02-01 00:00:00
abstract::Electric pulp testers (EPTs) are widely used to assess tooth pulp vitality. With many unipolar EPTs the electrical circuit is completed through the operator. Since dentists now routinely wear rubber gloves, these might be expected to provide electrical insulation, and therefore to break the circuit. The objective of t...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1989.tb00516.x
更新日期:1989-09-01 00:00:00
abstract::Rectified turpentine oil can be used to soften or dissolve gutta-percha in the root canal space to facilitate endodontic retreatment or preparation of space for a post. For endodontic retreatment, the turpentine oil can be heated to 71 degrees C which significantly increases its ability to dissolve gutta-percha. For r...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1996.tb01167.x
更新日期:1996-03-01 00:00:00
abstract:AIM:To assess the inflammatory potential of biofilm matrix constituents of Enterococcus faecalis and Pseudomonas aeruginosa monospecies biofilms on macrophages. METHODOLOGY:In vitro biofilms of E. faecalis and P. aeruginosa were grown (7 days) in aerobic and anaerobic conditions. The biofilm matrix components: exopoly...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13093
更新日期:2019-07-01 00:00:00
abstract:AIM:To elucidate mechanisms by which mineral trioxide aggregate (MTA) suppresses pro-inflammatory cytokine mRNA expression in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. METHODOLOGY:Mineral trioxide aggregate extracts were prepared by immersing set ProRoot MTA in culture medium. RAW264.7 cells were cultu...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13386
更新日期:2020-12-01 00:00:00
abstract:AIM:To assess the success rate of the root-end filling material, Mineral Trioxide Aggregate (MTA). METHODOLOGY:Referred adult patients were recruited using strict entry criteria and randomly allocated to receive MTA or IRM. A standardized surgical technique was employed: the root end was resected perpendicularly and a...
journal_title:International endodontic journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2591.2003.00682.x
更新日期:2003-08-01 00:00:00
abstract:AIM:To compare several parameters of root canal preparation using two different rotary nickel-titanium (Ni-Ti) instruments: FlexMaster (VDW, Munich, Germany) and HERO 642 (Micro-Mega, Besançon, France). METHODOLOGY:Fifty extracted human mandibular molars with root canal curvatures between 20 and 40 degrees were embedd...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.2003.00664.x
更新日期:2003-05-01 00:00:00
abstract:AIM:To evaluate, using an experimental immature tooth model, the fracture resistance of bovine incisors submitted to different reinforcement treatments with mineral trioxide aggregate (MTA). METHODOLOGY:An immature tooth model was created by sectioning the coronal and apical portions of 40 bovine incisors 8 mm above a...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2007.01266.x
更新日期:2007-09-01 00:00:00
abstract:AIM:To devise an optimal protocol and to analyse the leucocyte composition of periapical (PA) lesions by flow cytometry. METHODOLOGY:PA lesions were mechanically agitated, with and without proteolysis. This was with either 0.2% collagenase alone, or in combination with 0.02% DNA-ase in serial incubations until all tis...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.2000.00294.x
更新日期:2000-03-01 00:00:00
abstract::The effects of varying clinically relevant patterns of anaesthetic-vasoconstrictor combinations used for periradicular surgery on plasma concentrations of catecholamines and haemodynamic responses was studied in the canine model. Five mongrel dogs were anaesthetized with sodium pentobarbitol. A femoral cannula was ins...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1996.tb01357.x
更新日期:1996-01-01 00:00:00
abstract:AIM:To elucidate the expressions of MMP-8 and MMP-13 in experimentally induced rat periradicular lesions by means of the reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemical staining. METHODOLOGY:Thirty rats were used and periradicular lesions in mandibular first molar teeth were establishe...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2011.01880.x
更新日期:2011-08-01 00:00:00
abstract::The apical seal produced by low-temperature injection of gutta-percha, with or without root canal sealer, in the presence or absence of the smear layer was evaluated quantitatively using an electrochemical technique. The root canals of 44 teeth were prepared with the smear layer intact following a final flush of NaOCl...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1994.tb00236.x
更新日期:1994-03-01 00:00:00