The effect of infliximab, a monoclonal antibody against TNF-alpha, on disc herniation resorption: a randomized controlled study.

abstract：:The purpose of this study is to describe the biology of spinal lengthening (vertebrodiatasis) in a juvenile goat model. A small Orthofix dynamic fixator was affixed to 5.5 mm pedicular halfpins placed bilaterally at T12, L1, L5 and L6 in six juvenile goats. Distraction was performed across vertebral endplates between ...

journal_title：Spine

authors： Stefko RM,Cain JE Jr,Lauerman WC 2nd,Brann C,Platenburg RC,Pyka R

更新日期：1993-09-15 00:00:00

abstract：STUDY DESIGN:A retrospective review of a case of coccygodynia caused by a previously unreported coccygeal morphology. OBJECTIVES:To draw attention to a previously undiagnosed pathology. BACKGROUND:This case adds to the recently described variants of coccygeal anatomy. METHODS:The authors present the case of a 42-yea...

journal_title：Spine

authors： Dennell LV,Nathan S

更新日期：2004-06-15 00:00:00

abstract：:Seventeen patients were identified with concomitant thoracolumbar and sacral fractures representing 26% of sacral fractures and 7.7% of pelvic fractures. The thirteen men and four women exhibited a bimodal age distribution. There were thirteen vertical compression thoracolumbar fractures, three transverse process frac...

journal_title：Spine

authors： Albert TJ,Levine MJ,An HS,Cotler JM,Balderston RA

更新日期：1993-08-01 00:00:00

abstract：STUDY DESIGN:A case report. OBJECTIVE:The authors present a rare case of metastatic nonfunctioning neuroendocrine tumor of the pancreas presenting as thoracic spinal cord compression. SUMMARY OF BACKGROUND DATA:Pancreatic endocrine tumors (PETs) are a slow-growing subset of pancreatic tumors. They can be classified a...

journal_title：Spine

authors： Eads TA,Hattab EM,Rodgers RB

更新日期：2010-05-15 00:00:00

abstract：STUDY DESIGN:Case report and clinical discussion. OBJECTIVE:To describe a rare case of metastatic pulmonary intimal sarcoma presenting as cauda equine syndrome. SUMMARY OF BACKGROUND DATA:Pulmonary artery sarcoma is a rare tumor, frequently misdiagnosed as pulmonary embolism, and although it is highly aggressive, met...

journal_title：Spine

authors： Rashid A,Molloy S,Lehovsky J,Tirabosco R,Hughes R,Butt S

更新日期：2008-07-01 00:00:00

abstract：STUDY DESIGN:An in vitro human cadaveric study comparing the effects of anterior and posterior sequential destabilization conditions on thoracic functional unit mechanics was studied. OBJECTIVES:To investigate the biomechanical properties of the human thoracic spine. SUMMARY OF BACKGROUND DATA:Few studies have addres...

journal_title：Spine

authors： Oda I,Abumi K,Cunningham BW,Kaneda K,McAfee PC

更新日期：2002-02-01 00:00:00

abstract：STUDY DESIGN:A comparative analysis of electromyogram (EMG) signals of patients of cervical pain and normal controls. OBJECTIVES:To determine the differences between frequency and time domain parameters of EMG signals of patients of cervical pain and normal controls. SUMMARY OF BACKGROUND DATA:No diagnostic technique...

journal_title：Spine

authors： Kumar S,Narayan Y,Prasad N,Shuaib A,Siddiqi ZA

更新日期：2007-04-15 00:00:00

abstract：STUDY DESIGN:A retrospective review series. OBJECTIVE:To identify vascular anatomy and esophageal deviations that may interfere with a percutaneous anterior approach in cervical spine surgery. SUMMARY OF BACKGROUND DATA:The percutaneous anterior approach has been used for minimally invasive interventions of cervical ...

journal_title：Spine

authors： Jeon JK,Oh CH,Chung D,Lee J,Choi SH,Choi E,Ji GY

更新日期：2014-02-15 00:00:00

abstract：STUDY DESIGN:Retrospective radiographic analysis. OBJECTIVE:To retrospectively review a group of patients undergoing anterior cervical discectomy and fusion (ACDF) to determine the relative risk of adjacent level disc degeneration after incorrect needle localization. SUMMARY OF BACKGROUND DATA:The needle puncture tec...

journal_title：Spine

authors： Nassr A,Lee JY,Bashir RS,Rihn JA,Eck JC,Kang JD,Lim MR

更新日期：2009-01-15 00:00:00

abstract：STUDY DESIGN:An investigation of the reliability of various factors used to analyze electromyograms of paraspinal muscles of the lumbar spine. OBJECTIVES:To determine the reproducibility of several electromyographic variables over time and to assess the influence of confounding factors. SUMMARY OF BACKGROUND DATA:Pre...

journal_title：Spine

authors： Nargol AV,Jones AP,Kelly PJ,Greenough CG

更新日期：1999-05-01 00:00:00

abstract：STUDY DESIGN:This study analyzed immunohistological features of the extruded or sequestrated intervertebral disc of the lumbar spine. To clarify the pathogenesis of neovascularization, cells isolated from herniated disc were cultured and examined biologically. OBJECTIVES:The objectives of this study were to characteri...

journal_title：Spine

authors： Doita M,Kanatani T,Harada T,Mizuno K

更新日期：1996-01-15 00:00:00

abstract：STUDY DESIGN:Repeated measures experimental study of the effect of flexion-relaxation, recovery, and gender on paraspinal reflex dynamics. OBJECTIVE:To determine the effect of prolonged flexion-relaxation and recovery time on reflex behavior in human subjects. SUMMARY OF BACKGROUND DATA:Prolonged spinal flexion has b...

journal_title：Spine

authors： Rogers EL,Granata KP

更新日期：2006-04-01 00:00:00

abstract：:Electrically evoked compound action potentials were used to quantify the neurophysiologic abnormalities caused by application of chymopapain into the lumbar spinal canal in rats. A branch of the sciatic nerve was stimulated with voltage impulses of constant amplitude (40 V) and duration (0.1 msec) at the right externa...

journal_title：Spine

authors： Wehling P,Pak MA,Cleveland SJ,Schulitz KP

更新日期：1989-01-01 00:00:00

abstract：:A biomechanical model for studying lumbar muscle load sharing for a class of physical tasks that involve gravitational loading (holding weights) of the upper body in an erect posture is presented. The model assumes that the lumbar muscles balance the externally applied flexion and lateral bending moments. The concept ...

journal_title：Spine

authors： Ladin Z,Murthy KR,De Luca CJ

更新日期：1989-09-01 00:00:00

abstract：STUDY DESIGN:An experimental study of cardiovascular complications that arise during vertebroplasty was conducted. OBJECTIVE:To investigate the sequential occurrence of fat embolism and hypotension during vertebroplasty. SUMMARY OF BACKGROUND DATA:Vertebroplasty, the augmentation of vertebrae with polymethylmethacryl...

journal_title：Spine

authors： Aebli N,Krebs J,Davis G,Walton M,Williams MJ,Theis JC

更新日期：2002-03-01 00:00:00

abstract：:We used survivorship analysis to study 21 burst fractures that were treated with posterior VSP spine implant and fusion, each of which was over two motion segments. There were two treatment classes: 1) eight patients whose surgery included anterior bone grafting (augmentation), seven of which were done by the transped...

journal_title：Spine

authors： Ebelke DK,Asher MA,Neff JR,Kraker DP

更新日期：1991-08-01 00:00:00

abstract：STUDY DESIGN:Literature review. OBJECTIVES:To assess the frequency of lumbar fusion procedures in the United States; changes in the incidence of fusion in the past 12 years; variations in fusion procedure rates among geographic regions of the nation and between the United States and other countries; costs of lumbar fu...

journal_title：Spine

authors： Katz JN

更新日期：1995-12-15 00:00:00

abstract：STUDY DESIGN:A prospective double-blind randomized trial in 31 patients. OBJECTIVES:To assess the clinical efficacy of percutaneous radiofrequency denervation of the lumbar zygapophysial joints in reducing pain, functional disability, and physical impairment in patients with back pain originating from the lumbar zygap...

journal_title：Spine

authors： van Kleef M,Barendse GA,Kessels A,Voets HM,Weber WE,de Lange S

更新日期：1999-09-15 00:00:00

abstract：:Lumbar disc herniation is a common condition with a favorable prognosis in the majority of circumstances. This article reviews the published scientific evidence regarding the impact of nonoperative care on this condition. The published studies are critiqued and evaluated on their relative strengths and weaknesses. The...

journal_title：Spine

authors： Saal JA

更新日期：1996-12-15 00:00:00

abstract：STUDY DESIGN:Systematic literature review. OBJECTIVE:To categorize published evidence systematically for lumbar fusion for chronic low back pain (LBP) in order to provide an updated and comprehensive analysis of the clinical outcomes. SUMMARY OF BACKGROUND DATA:Despite a large number of publications of outcomes of sp...

journal_title：Spine

authors： Phillips FM,Slosar PJ,Youssef JA,Andersson G,Papatheofanis F

更新日期：2013-04-01 00:00:00

abstract：STUDY DESIGN:A prospective, randomized clinical study comparing beta-tricalcium phosphate (beta-TCP) with autograft bone graft with follow-up of 3 years. OBJECTIVE:To determine the efficacy of beta-TCP as a bone graft substitute combined with local autograft obtained from decompression compared with the use of autolog...

journal_title：Spine

authors： Dai LY,Jiang LS

更新日期：2008-05-20 00:00:00

abstract：:Details of ten new cases of spondylothoracic dysplasia (the Jarcho-Levin syndrome) are presented. During follow-up, lasting between 8 and 21 years, two children in this group died. Our observations did not confirm Heilbronner's theory concerning the existence of two distinctive types of this syndrome: Type 1 or fatal,...

journal_title：Spine

authors： Herold HZ,Edlitz M,Baruchin A

更新日期：1988-05-01 00:00:00

abstract：STUDY DESIGN:A new in vivo sheep model was developed that produced disc degeneration through the injection of 5-bromodeoxyuridine (BrdU) into the intervertebral disc. This process was studied using magnetic resonance imaging (MRI), radiography, CT/discogram, histology, and biochemistry. OBJECTIVES:To develop a sheep m...

journal_title：Spine

authors： Zhou H,Hou S,Shang W,Wu W,Cheng Y,Mei F,Peng B

更新日期：2007-04-15 00:00:00

abstract：STUDY DESIGN:A case report of traumatic atlanto-occipital dislocation managed by transarticular screw fixation. OBJECTIVES:To present a case with initial failed wire fixation but successful reduction and fixation with transarticular screw fixation and occipitocervical plate stabilization. SUMMARY OF BACKGROUND DATA:A...

journal_title：Spine

authors： Grob D

更新日期：2001-03-15 00:00:00

abstract：:This article presents the content and the application criteria of a questionnaire intended for the study of spinal disorders in workers and the results of an investigation, carried out via this questionnaire, in a group of 1205 male workers not exposed to occupational risks for the spine either currently or in the pas...

journal_title：Spine

authors： Occhipinti E,Colombini D,Grieco A

更新日期：1993-07-01 00:00:00

abstract：STUDY DESIGN:Immunohistochemistry for tumor necrosis factor (TNF) and protein gene product (PGP) 9.5 in vertebral endplates of patients with discogenic low back pain and Modic Type 1 or Type 2 endplate changes on MRI. OBJECTIVES:To examine whether inflammatory cytokines and nerve in-growth into the vertebral endplate ...

journal_title：Spine

authors： Ohtori S,Inoue G,Ito T,Koshi T,Ozawa T,Doya H,Saito T,Moriya H,Takahashi K

更新日期：2006-04-20 00:00:00

abstract：STUDY DESIGN:Retrospective study. OBJECTIVE:To report results at a minimum 5 years after pedicle subtraction osteotomy for fixed sagittal imbalance. SUMMARY OF BACKGROUND DATA:No one has reported results of pedicle subtraction osteotomies with a 5- to 8-year follow-up. METHOD:Thirty-five consecutive patients with sa...

journal_title：Spine

authors： Kim YJ,Bridwell KH,Lenke LG,Cheh G,Baldus C

更新日期：2007-09-15 00:00:00

abstract：STUDY DESIGN:Histologic analysis of intervertebral disc (IVD) in three types of transgenic mice. OBJECTIVE:To investigate the role of Wnt/β-catenin signaling in regulation of IVD development and organization. SUMMARY OF BACKGROUND DATA:β-catenin dependent Wnt signaling is one of the central regulators in cartilage de...

journal_title：Spine

authors： Kondo N,Yuasa T,Shimono K,Tung W,Okabe T,Yasuhara R,Pacifici M,Zhang Y,Iwamoto M,Enomoto-Iwamoto M

更新日期：2011-04-15 00:00:00

abstract：:Thirty-four patients with traumatic distractive flexion injuries in the mid to lower cervical spine were treated with posterior wire stabilization without bony fusion from January 1981 through May 1987. Fifteen had cord involvement, and nine had root involvement. Ten were neurologically intact. Thirty patients were fo...

journal_title：Spine

authors： Feldborg Nielsen C,Annertz M,Persson L,Wingstrand H,Säveland H,Brandt L

更新日期：1991-04-01 00:00:00

abstract：STUDY DESIGN:Analysis of a prospective multicenter database. OBJECTIVE:To assess the ability of the recently created Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) to predict odds of major complications and length of hospital stay for patients who had more severe preoperative deformity and underwent more invasive...

journal_title：Spine

authors： Miller EK,Lenke LG,Neuman BJ,Sciubba DM,Kebaish KM,Smith JS,Qiu Y,Dahl BT,Pellisé F,Matsuyama Y,Carreon LY,Fehlings MG,Cheung KM,Lewis S,Dekutoski MB,Schwab FJ,Boachie-Adjei O,Mehdian H,Bess S,Shaffrey CI,Ames CP

更新日期：2018-10-15 00:00:00