The etiology of hypertension in the metabolic syndrome part two: the gene-environment interaction.

Abstract:

:The pathogenesis of obesity, insulin resistance and hypertension begins with an interaction between genetic factors and environmental factors. The search for the underlying genetic basis of these conditions has yielded disappointing results. It is possible that the importance of environmental influences has been underestimated. In Part Two of our series of reviews, we discuss the key genetic, environmental and evolutionary influences which lead to the development of these conditions, and provide a detailed account of the mechanisms by which these influences produce their effects.

journal_name

Curr Vasc Pharmacol

authors

Sharma V,McNeill JH

doi

10.2174/157016106778521661

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

305-20

issue

4

eissn

1570-1611

issn

1875-6212

journal_volume

4

pub_type

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