Stable genes.

abstract：:The authors sought to establish whether maternal dietary methanol during pregnancy was a factor in the etiology of autism spectrum disorders. A seven item questionnaire was given to women who had given birth to at least one child after 1984. The subjects were solicited from a large primary care practice and several in...

journal_title：Medical hypotheses

authors： Walton RG,Monte WC

更新日期：2015-10-01 00:00:00

abstract：:At present, researchers are still debating the effect of blue light on the eyes.Studies have shown thatwhile blue lighthelpsto maintain normal biological rhythms,excessive blue light radiation mayinduce fundus lesions. The preliminary survey shows that the incidence of vitreous floaters is high among digital device us...

journal_title：Medical hypotheses

authors： Chen JT,Wu HJ

更新日期：2020-06-01 00:00:00

abstract：:We suggest that polymyalgia rheumatica with giant cell arteritis (PR-GCA) is an arachidonic acid metabolites mediated disease which can be diagnosed more accurately and monitored more precisely for therapeutic benefits by the serial determinations of the major urinary prostaglandin F, serum urinary lysozymes, serum ac...

journal_title：Medical hypotheses

authors： Nalbandian RM,Henry RL,Williams GA,Fleischman JA,O'Donnell FE Jr,Reeser FH

更新日期：1981-09-01 00:00:00

abstract：:Mental retardation is a progressive condition in Down syndrome: intelligence starts to decline linearly within the first year. This phenomenon could be related to the overproduction of a toxic compound, hydrogen sulfide. Indeed, a gene located on chromosome 21 controls the production of cystathionine-β-synthase, an en...

journal_title：Medical hypotheses

authors： Kamoun PP

更新日期：2019-10-01 00:00:00

abstract：:Exercise is a key component for prevention and treatment of type 2 diabetes. However, diabetes complications affect exercise habits. Computerized clinical decision support systems (CCDSSs) may help specialists improve their decision-making abilities in the management of diseases. We hypothesized that patients' diabeti...

journal_title：Medical hypotheses

authors： Ozdemir F,Ari A,Kilcik MH,Hanbay D,Sahin I

更新日期：2020-10-01 00:00:00

abstract：:Selective serotonin re-uptake inhibitors (SSRIs), has been increasingly used for the treatment of premature ejaculation over the past 5 years. It was reported that folic acid plays important roles in synthesis of 5-HT. Therefore, we hypothesize that folic acid supplementation may cures premature ejaculation by the sam...

journal_title：Medical hypotheses

authors： Yin TL,Yang J,Zhang B,Yan WJ,Xu WM,Li W,Yu L,Li SJ,Wu GX

更新日期：2011-03-01 00:00:00

abstract：:The cancer cell appears to contain two non phosphorylating glycolytic pathways in addition to phosphorylating glycolysis and the aerobic citric acid and phosphogluconate cycles. It is hypothesised that these pathways are all interconnected and in the static adult cell non phosphorylating glycolysis is in a state of co...

journal_title：Medical hypotheses

authors： Holt JA

更新日期：1983-02-01 00:00:00

abstract：:In this study, after having formed the hypothesis of the existence of a "Compensating Center" (cerebral?) that orders the increase in the function of one kidney in case of deterioration of its congener, we propose two mechanisms that may lead to the activation of this Center. The first may be the difference between th...

journal_title：Medical hypotheses

authors： Collard M

更新日期：1988-03-01 00:00:00

abstract：:Coronavirus Diseases-2019 (COVID-19) has caused a large global outbreak and has been declared as a pandemic by the World Health Organization (WHO). It has been proposed that COVID-19-related hyperinflammation and dysregulated immune response might play a critical role in developing a cytokine storm which usually progr...

journal_title：Medical hypotheses

authors： Ali ZA,El-Mallakh RS

更新日期：2020-11-01 00:00:00

abstract：:The dominant role of the physical and chemical environment in the development of cancer is challenged. Analyses of the etiology of skin, bladder, respiratory and gastric cancers are presented which demonstrate the considerable extent to which one's health status may modify the initiation and promotion of environmental...

journal_title：Medical hypotheses

authors： Calabrese EJ

更新日期：1979-01-01 00:00:00

abstract：:Numerous studies indicate that aberrant amyloid precursor protein metabolism, elevated peroxidative damage, depressed energy metabolism and altered calcium homeostasis are four pivotal deleterious factors in the pathogenesis of Alzheimer's disease. Cumulative evidence further suggests that these four factors are intim...

journal_title：Medical hypotheses

authors： Ying W

更新日期：1996-05-01 00:00:00

abstract：:The authors support the hypothesis that a causative agent in Parkinson's disease (PD) might be either fungus or bacteria with fungus-like properties - Actinobacteria, and that their spores may serve as 'infectious agents'. Updated research and the epidemiology of PD suggest that the disease might be induced by environ...

journal_title：Medical hypotheses

authors： Berstad K,Berstad JER

更新日期：2017-07-01 00:00:00

abstract：:Styrene is one of the most important plastic monomers worldwide. Styrene-7,8-oxide (SO), the major in-vivo metabolite of styrene, is classified as probably carcinogenic to humans and carcinogenic in rodents. Biological monitoring of exposure to styrene is usually carried out by determination of mandelic acid and pheny...

journal_title：Medical hypotheses

authors： Marczynski B,Peel M,Baur X

更新日期：2000-04-01 00:00:00

abstract：:Since forced unilateral nostril breathing activates the contralateral brain hemisphere, an animal analogue of this technique could be provided by methylmethacrylate gluing large plastic pellets in either the right or left nostrils in a group of rats. A large number of physiological, pharmacological, and immunological ...

journal_title：Medical hypotheses

authors： Backon J

更新日期：1989-03-01 00:00:00

abstract：:Placebo controlled trials in disease states as currently constituted are designed to show a drug "works" when in fact it may not. Efficacy of this type may be constructed in trials that demonstrate some marginal superiority of a drug over placebo in disease states that do not take into account any potentialities of th...

journal_title：Medical hypotheses

authors： Healy D

更新日期：2010-05-01 00:00:00

abstract：:This paper treats evidence for an increasing recognition of a force with intangible properties in biosystems with special reference to its ability to transport electrons at near 0 degree Kelvin. It is implied that such force, whose demonstration at these temperatures is an experimental contrivance to emphasise its str...

journal_title：Medical hypotheses

authors： Reid BL

更新日期：1995-06-01 00:00:00

abstract：:Boron is increasingly added to food supplements due to multiple effects that have been reported in mammals after boric acid administration. Among these effects are inflammatory process control, bone and muscle strength enhancement, protein expression regulation, and a decreased risk of developing some pathologies in w...

journal_title：Medical hypotheses

authors： Bello M,Guadarrama-García C,Velasco-Silveyra LM,Farfán-García ED,Soriano-Ursúa MA

更新日期：2018-09-01 00:00:00

abstract：:Myeloid-derived suppressor cells (MDSCs) accumulate in tumor-bearing hosts and play an essential role in tumor-associated immunosuppression, which hampers effective immunotherapeutic approaches. MicroRNAs (miRNAs) are short noncoding RNAs that negatively regulate target gene expression at the posttranscriptional level...

journal_title：Medical hypotheses

authors： Tian J,Rui K,Wang S

更新日期：2014-08-01 00:00:00

abstract：:The globally increasing incidences of Type 1 diabetes (T1DM) and Type 2 diabetes (T2DM) can have a common background. If challenged by the contemporary high level of nutritional glucose stimulation, the β-cells in genetically predisposed individuals are at risk for damage which can lead to the diseases. The fat to car...

journal_title：Medical hypotheses

authors： Sjöblad S

更新日期：2019-04-01 00:00:00

abstract：:Oral administration of L-arginine in pharmacological doses induces growth hormone and insulin-like growth factor-I responses and stimulates nitric oxide synthesis. Growth hormone and insulin-like growth factor-I are important mediators of bone turnover and osteoblastic bone formation, while nitric oxide is a potent in...

journal_title：Medical hypotheses

authors： Visser JJ,Hoekman K

更新日期：1994-11-01 00:00:00

abstract：:Although the classical ideal is that scientific theories are evaluated by a careful teasing-out of their internal logic and external implications, and checking whether these deductions and predictions are in-line-with old and new observations; the fact that so many vague, dumb or incoherent scientific theories are app...

journal_title：Medical hypotheses

authors： Charlton BG

更新日期：2008-09-01 00:00:00

abstract：:A recent published model described the phenomenon of a global panic reaction (GPR) on the stock markets based on two remarkable stock market crashes in the months of January and March [Sperling W, Bleich S, Reulbach U, Black Monday on stock markets throughout the world - a new phenomenon of collective panic disorder? ...

journal_title：Medical hypotheses

authors： Sperling W,Biermann T

更新日期：2009-11-01 00:00:00

abstract：:In this editorial, we provide concise suggestions to help individuals decide what scientific papers to read and how to read them. We do so because--like others--we are frequently asked by people with interest in science as to how to effectively surf today's information tsunami. This is particularly important in, but n...

journal_title：Medical hypotheses

authors： Erren TC,Cullen P,Erren M

更新日期：2009-09-01 00:00:00

abstract：:Sperm production is regulated by inhibin. Inhibin secretion may be controlled by the number of ejaculations. The more the number of ejaculations, the less the inhibin in blood and the more the production of spermatozoa. ...

journal_title：Medical hypotheses

authors： Skandhan KP

更新日期：1989-10-01 00:00:00

abstract：:Studies have suggested that the brain renin angiotensin system (RAS) regulates cerebral flow, autonomic and hormonal systems, stress, innate immune response and behavior, being implicated in several brain disorders such as major depression, Parkinson's and Alzheimer's disease. The angiotensin II receptor subtype 1 (AT...

journal_title：Medical hypotheses

authors： de Góis Queiroz AI,Medeiros CD,Ribeiro BM,de Lucena DF,Macêdo DS

更新日期：2013-03-01 00:00:00

abstract：:Gastroesophageal reflux (GER) and asthma have been linked, but the true nature of this relationship is incompletely understood. Most of the literature examining this association has implicated GER as the factor contributing to asthma. GER has also been linked to conditions of the upper airway like sinusitis and obstru...

journal_title：Medical hypotheses

authors： Turbyville JC

更新日期：2010-06-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a new therapeutic approach for the treatment of malignant tumors. Hyperbaric oxygen (HBO(2)) shows beneficial effects in various modalities of cancer interventions. Tumor cells tend to accumulate large amount of iron. There is interaction between tissue content of oxygen, iron, free radic...

journal_title：Medical hypotheses

authors： Al-Waili NS,Butler GJ

更新日期：2006-01-01 00:00:00

abstract：:Low carbohydrate high fat (LCHF) diets are emerging in popularity. Several athletics have adopted LCHF diets in an attempt to improve exercise performance and body composition by enhancing fat utilization. However, these diets impair maximal and supramaximal exercise performance due to limited glycogen stores as well ...

journal_title：Medical hypotheses

authors： Kaviani M,Izadi A,Heshmati J

更新日期：2021-01-01 00:00:00

abstract：:Skin cells produce endogenous opioids in response to light. This results in increased skin and plasma levels of endogenous opioids. Increased plasma levels of endogenous opioids may improve mood and affect behavior. The author suggests that improvement in mood after exposure to light may be related to the light-induce...

journal_title：Medical hypotheses

authors： Sher L

更新日期：2001-11-01 00:00:00

abstract：:The DSM is not brain-related and is thus unable to relate clinical assessments to putative brain disturbances. 'Clinical brain profiling' (CBP) involves the rearrangement of clinical findings to assess the relevant disturbances in brain dynamics. CBP has three major pathological dimensions, (1) disorders of basic brai...

journal_title：Medical hypotheses

authors： Peled A

更新日期：2009-08-01 00:00:00