Abstract：
:Two genetically diverse strains of Trypanosoma cruzi were tested in vitro for susceptibility to the solanum-derived triglycoside alkaloids solasonine and solamargine. Cytolytic assays were performed on epimastigotes (EMs) and bloodstream form trypomastigotes (BSFs) lifecycle stages by using serial dilutions of each alkaloid. Each alkaloid effectively lysed both lifecycle stages, although solasonine routinely required higher concentrations to induce similar results. EMs demonstrated greater resistance to cytolysis than BSFs at equal concentrations of either alkaloid. No significant resistance could be correlated to parasite strain. The reported synergistic cytolytic effects observed upon compounding solasonine and solamargine together were also tested. We failed to identify any cytolytic synergism in cultures of EMs or BSFs. The role of rhamnose-binding proteins (RBPs) in mediating cytolysis was investigated through competitive inhibition experiments. The addition of exogenous L: -rhamnose to the media failed to reduce parasite attrition independent of the parasite lifecycle stage. Based on these results, we suggest the mechanisms involved in cytolysis of T. cruzi by solasonine and solamargine are largely independent of rhamnose receptor-specific interactions. We propose that attrition likely involves less-specific carbohydrate interactions, which lead to the formation and intercalation of sterol complexes into the parasite plasma membrane.
journal_name
J Chem Ecoljournal_title
Journal of chemical ecologyauthors
Hall CA,Hobby T,Cipollini Mdoi
10.1007/s10886-006-9153-5subject
Has Abstractpub_date
2006-11-01 00:00:00pages
2405-16issue
11eissn
0098-0331issn
1573-1561journal_volume
32pub_type
杂志文章abstract：:Phytotoxicity-directed extraction and fractionation of the aerial parts of Mikania micrantha H.B.K. led to the isolation and identification of three sesquiterpenoids: dihydromikanolide, deoxymikanolide, and 2,3-epoxy-1-hydroxy-4,9-germacradiene-12,8:15,6-diolide. These sesquiterpenoids inhibited both germination and s...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-005-5805-0
更新日期：2005-07-01 00:00:00
abstract：:Splitless capillary gas chromatography indicated the presence of (Z)- and (E)-11-tetradecenyl acetate and (Z)-11-tetradecenyl alcohol in the washes of female abdominal tips of the blackheaded fireworm,Rhopobota naevana (Hubner). Gas chromatography combined with mass spectroscopy confirmed the presence of tetradecenyl ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01020546
更新日期：1987-05-01 00:00:00
abstract：:TheMaladera matrida beetle (Coleoptera, Scarabaeidae, Melolonthinae), a relatively new species to science, was first identified in Israel in 1983. In the course of field observations it was found that adultM. matrida beetles emerged from the soil at sunset to feed and mate. During the first 20 min of flight, most of t...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF02036200
更新日期：1994-10-01 00:00:00
abstract：:The role of volatile infochemicals emitted by feces of larvae in the host-searching behavior of the parasitoidCotesia rubecula was evaluated during single- and dual-choice tests inside a wind tunnel. The following treatments were tested: feces produced by second and fourth instars ofPieris rapae (preferred host), seco...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF02033677
更新日期：1995-11-01 00:00:00
abstract：:Analyses of two-dimensional chromatographic flavonoid patterns of butterflies reared on different grass species have shown that the flavonoid pattern ofMelanargia galathea is dependent on the flavonoid content of the larval diet. This confirms the dietary origin of flavonoid pigments inM. galathea. The flavonoid patte...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01024106
更新日期：1985-09-01 00:00:00
abstract：:The identification of pheromones and chemicals that may inhibit or stimulate growth and reproduction necessarily leads to the consideration of biochemical methods to isolate and characterize these molecules. Analysis ofSchistosoma mansoni surface antigens by direct radioiodination, metabolic labeling with tritiated an...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01022388
更新日期：1986-08-01 00:00:00
abstract：:The olfactory system of living organisms can accurately discriminate numerous odors by recognizing the pattern of activation of several odorant receptors (ORs). Thus, development of an odorant sensor array based on multiple ORs presents the possibility of mimicking biological odor discrimination mechanisms. Recently, ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-016-0726-7
更新日期：2016-07-01 00:00:00
abstract：:The species of desert-dwelling ants of the Cataglyphis bicolor (Hymenoptera: Formicidae) group are difficult to distinguish by morphological features. Analysis of the secretion from the Dufour glands of workers of a number of colonies was undertaken to see if it provided a clear test of species. Linked 6c-ms showed in...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1023/a:1013521123356
更新日期：2002-01-01 00:00:00
abstract：:Headspace extracts obtained from agar plate cultures of two marine bacteria from the North Sea (Germany), Loktanella strain BIO-204 and Dinoroseobacter shibae strain DFL-27, were analyzed by GC-MS. Several gamma-lactones and one delta-lactone were identified, besides pyrazines and some sulfur compounds. The absolute c...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-005-3553-9
更新日期：2005-04-01 00:00:00
abstract：:Fleshy fruits contain a myriad of secondary metabolites that may fulfill various non-mutually exclusive ecological functions. Among them are defense against pathogens and herbivores, manipulation of frugivores' gut retention time, or controlling the germination process. In addition, it has been suggested that aroma co...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-016-0687-x
更新日期：2016-04-01 00:00:00
abstract：:Nitrogen-limited plants ofHeterotheca subaxillaris accumulate greater quantities of leaf volatile terpenes than do nitrogen-rich plants. A series of feeding trials were performed to determine if such nitrate-limited plants are better defended against generalist-feeding insect herbivores. Soybean looper (Pseudoplusia i...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01012871
更新日期：1987-11-01 00:00:00
abstract：:Coccinellid beetles contain a variety of defensive alkaloids that render them unpalatable to predators. Epilachna paenulata (Coleoptera: Coccinellidae) is a South American ladybird beetle that feeds on plants of the Cucurbitaceae family. The defensive chemistry of E. paenulata has been characterized as a mixture of sy...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-008-9570-8
更新日期：2009-01-01 00:00:00
abstract：:Red imported fire ants, Solenopsis invicta Buren, build nests by excavating soil. Incorporation of ant-derived chemicals in nesting material has long been known; however, only a few chemicals have been identified. This paucity of identified ant-derived chemicals may be due to the interference from soil-borne compounds...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-006-9249-y
更新日期：2007-03-01 00:00:00
abstract：:The feasibility of using the synthetic sex pheromone, disparlure, as a mating confusant of the nun moth (Lymantria monacha L.) was investigated on wild populations occurring in outbreak proportions in Poland and in low density in Czechoslovakia. The size of experimental plots ranged from 1 to 12 hectares. The amounts ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01013905
更新日期：1988-02-01 00:00:00
abstract：:Repellency and toxicity of 8 essential oils (vetiver grass, cassia leaf, clove bud, cedarwood, Eucalyptus globules, Eucalyptus citrodora, lemongrass and geranium) were evaluated against the Formosan subterranean termite, Coptotermes formosanus Shiraki. Vetiver oil proved the most effective repellent because of its lon...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1023/a:1010410325174
更新日期：2001-08-01 00:00:00
abstract：:Selected combinations of (Z)-5-decenyl, (Z)-7-dodecenyl, and (Z)-9-tetradecenyl acetates, the pheromone components of the turnip mothAgrotis Segetum were tested for field attractancy at six, two, and three sites in Europe, Asia, and Africa, respectively. At all of the sites in Eurasia and in northern Africa the ternar...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF00994360
更新日期：1992-08-01 00:00:00
abstract：:The elytra of females of the white-spotted longhorn beetle, Anoplophora malasiaca (Coleoptera: Cerambycidae), are coated with a contact sex pheromone, which was previously shown to be composed of at least three chemical groups. Individually, the chemical groups had little pheromonal activity, but a blend of all three ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-019-01069-1
更新日期：2019-06-01 00:00:00
abstract：:The sweetpotato weevil, Cylas formicarius (Fabricius) (Coleoptera: Brentidae), is the most serious pest of sweetpotato around the world, damaging sweetpotatoes in the field and in storage, as well as being a quarantine pest. Because the larval period is spent within vines or tubers, and the adults are nocturnal, chemi...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-012-0160-4
更新日期：2012-07-01 00:00:00
abstract：:The cuticular chemicals of 124 individual wasps (foundresses and workers) from 23 colonies ofPolistes fuscatus were analyzed. The compounds identified, all of which were hydrocarbons, were similar to those of other vespid wasps in that the bulk of the hydrocarbons were 23-33 carbons in chain length. However, the hydro...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF02059889
更新日期：1994-07-01 00:00:00
abstract：:Hypericin, an anthrone dimer inHypericum perforatum (Guttiferae), is shown for the first time to be phototoxic to generalist lepidopteran larvae; survivorship was reduced and development prolonged forHeliothis zea (Noctuidae) andPlatynota flavedana (Tortricidae) that consumed hypericin diets in the presence of light. ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01015183
更新日期：1989-03-01 00:00:00
abstract：:Males ofCarpophilus antiquus Melsheimer (Coleoptera: Nitidulidae) emit an aggregation pheromone that was found to be a novel hydrocarbon, (3E,5E,7E,9E)-6,8-diethyl-4-methyl-3,5,7,9-dodecatetraene. A synthetic scheme and spectra (mass and proton NMR) are given for the compound. Beetles produced the pheromone when feedi...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF00979658
更新日期：1993-10-01 00:00:00
abstract：:Pharmacophagy of methyl eugenol (ME)--a highly potent male attractant, by Bactrocera papayae results in the hydroxylation of ME to sex pheromonal components, 2-ally-4,5-dimethoxyphenol (DMP) and (E)-coniferyl alcohol (CF). These compounds, which are also male attractants, are then sequestered and stored in the rectal ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1023/b:joec.0000048778.02561.70
更新日期：2004-11-01 00:00:00
abstract：:In addition to 2-methyl-4-heptanone, 6-methyl-5-hepten-2-one, and iridodials, the anal gland exudate of the dolichoderine ant,Tapinoma simrothi, contains 4-heptanone and 4-hydroxy-4-methyl-2-pentanone. The secretion functions as an alarm pheromone. ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF00990412
更新日期：1983-05-01 00:00:00
abstract：:The sex pheromone ofCydia toreuta (Grote), the eastern pine seedworm, was investigated using electroantennogram (AG) measurements, gas chromatography (combined GC-FID-EAD) measurements, and field tests. (E,Z)-8,10-dodecadienyl acetate (E,Z8,10-12:Ac) and (E,E)-8,10-dodecadienyl actetate (E,E8,10-12: Ac) produced both ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01014702
更新日期：1989-02-01 00:00:00
abstract：:Alate and apterous virginoparae ofAphis fabae Scop, and alate virginoparae ofBrevicoryne brassicae (L.), walking in a linear track olfactometer, were attracted by odor from leaves of their host plants.A. fabae responded to odor from undamaged but not damaged bean leaves. Gynoparae (autumn migrants) ofA. fabae, however...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01402946
更新日期：1991-06-01 00:00:00
abstract：:Insects use a wide range of structurally diverse pheromones for intra-specific communication. Compounds in the class of terpenes are emitted as sex, aggregation, alarm, or trail pheromones. Despite the common occurrence of terpene pheromones in different insect lineages, their origin from dietary host plant precursors...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-018-1019-0
更新日期：2019-02-01 00:00:00
abstract：:Phlorotannins are ubiquitous secondary metabolites in brown algae that are phenotypically plastic and suggested to have multiple ecological roles. Traditionally, phlorotannins have been quantified as total soluble phlorotannins. Here, we modify a quantification procedure to measure, for the first time, the amount of c...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/s10886-005-0984-2
更新日期：2005-01-01 00:00:00
abstract：:The four major components of the setal exudate of nymphs of the andromeda lace bug,Stephanitis takeyai, were identified. They are 7-hydroxy-3-nonylchromanone1, the novel 3,5-dihydroxy-2-dodecanoylcyclohex-2-en-1-one2,2',6'-dihydroxydodecanophenone3, and its 3-hydroxy derivative4. Only three species ofStephanitis commo...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01026934
更新日期：1990-07-01 00:00:00
abstract：:Roots of the carrot cultivars Vertou L.D. (resistant) and Long Chantenay (susceptible) were subjected to detailed chemical analysis to identify extracts and compounds influencing larval host-finding (preference/non-preference) behavior and to compare concentrations of these compounds in resistant and susceptible culti...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01012274
更新日期：1989-06-01 00:00:00
abstract：:The free amino acids have been shown by isolational work and choice bioassays to be more important than all other factors evaluated in defining leaf-feeding resistance of corn (Zea mays L.) to fall armyworm (FAW) [(Spodoptera frugiperda J.E. Smith)] larvae. 6-MBOA (6-methoxybenzoxazolinone) and maysin, toxins present ...
journal_title：Journal of chemical ecology
pub_type： 杂志文章
doi：10.1007/BF01020510
更新日期：1990-06-01 00:00:00
