Abstract:
:The aim of the study was to ascertain presence of Helicobacter pylori in gastric carcinoma as a responsible promoter of inflammatory-regenerative changes, which lead to pathological differentiation and transformation of normal epithelial cells into intestinal type and, in progression, cause epithelial dysplasia that develops into early gastric carcinoma. The paper presents prospective study that includes clinical, pathohistological and microbiological aspects of carcinogenesis initiation in gastric mucosa. The subjects are patients treated at Gastroenterohepatology Clinic divided into two groups. One group included 50 patients with gastric carcinoma while the control group included 50 patients with chronic atrophic H. pylori positive gastritis. All the patients were subjected to endoscopy as well as biopsy targeted at antrum, lesser curvature and corpus and at the region 1-2 cm removed from tumor lesion. We used HUT test to verify H. pylori presence in biopsy samples. We analyzed the samples for presence, frequency and severity of inflammatory-regenerative, metaplastic and dysplastic changes in gastric mucosa and evaluated their meaning for the prognosis. Our study confirmed Helicobaster pylori responsibility for inflammatory events in gastric mucosa in patients with gastric carcinoma. Slight and mild epithelial dysplasia with chronic atrophic gastritis grade I and II coupled with intestinal metaplasia may be considered an indicator for early detection of carcinoma. Such patients represent risk group for gastric carcinoma development.
journal_name
Bosn J Basic Med Scijournal_title
Bosnian journal of basic medical sciencesauthors
Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković Sdoi
10.17305/bjbms.2006.3146subject
Has Abstractpub_date
2006-08-01 00:00:00pages
57-60issue
3eissn
1512-8601issn
1840-4812journal_volume
6pub_type
杂志文章abstract::The aim of study was to evaluate endocrine changes in PCOS women during metformin treatment. One hundred women with PCOS, aged 20-40 years were included. A complete hormonal and metabolic pattern was recorded for each subject every 6 months. Metformin treatment after 6 and 12 months significantly reduced weight, BMI, ...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2013.2359
更新日期:2013-08-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
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doi:10.17305/bjbms.2014.4.99
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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abstract:BACKGROUND AND PURPOSE:Carcinoembryonic antigen (CEA) is used as a tumour marker in breast cancer (BC). In order to assess diagnostic value of CEA in BC we examined its serum levels and frequencies of its increase in breast cancer patients (BCP), and compared them to those in controls. We also determined CEA in patient...
journal_title:Bosnian journal of basic medical sciences
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
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更新日期:2003-03-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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更新日期:2015-01-22 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2007.3021
更新日期:2007-11-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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更新日期:2011-02-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2008.3005
更新日期:2008-02-01 00:00:00
abstract::Neutral red is a dye the azine structure which has been used as an acido-base indicator and a dye in histochemistry. In 1960 Goldhaber introduced Neutral red into the medium of resorbing bone cultures to localize the osteoclast in the living cultures. Using time-lapse microcinematography in order to follow the osteocl...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2007.3091
更新日期:2007-02-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2006.3135
更新日期:2006-08-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
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更新日期:2020-08-03 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2018.3560
更新日期:2019-11-08 00:00:00
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journal_title:Bosnian journal of basic medical sciences
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更新日期:2019-04-15 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2008.2882
更新日期:2008-11-01 00:00:00
abstract::The diagnostic performance of the Liver Imaging Reporting and Data System (LI-RADS) in differentiating hepatocellular carcinoma (HCC) from other hepatic malignancies has not been investigated in Chinese patients with chronic liver disease from hepatitis B virus (HBV) infection. The aim of this study was to evaluate th...
journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2019.4576
更新日期:2020-08-03 00:00:00
abstract::Most acute promyelocytic leukemia (APL) are characterized by reciprocal translocations t(15;17)(q22;21), which results in the fusion of PML gene at 15q22 with RARα gene at 17q21. However, several complex variant translocations also have been reported. Here we report a 62-year-old man with typical morphology and clinic...
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journal_title:Bosnian journal of basic medical sciences
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doi:10.17305/bjbms.2009.2827
更新日期:2009-05-01 00:00:00
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journal_title:Bosnian journal of basic medical sciences
pub_type: 杂志文章
doi:10.17305/bjbms.2018.3243
更新日期:2018-11-07 00:00:00
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doi:10.17305/bjbms.2011.2556
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