Abstract:
:Short hairpin RNAs can provide stable gene silencing via RNA interference. Recent studies have shown toxicity in vivo that appears to be related to saturation of the endogenous microRNA pathway. Will these findings limit the therapeutic use of such hairpins?
journal_name
Genome Bioljournal_title
Genome biologyauthors
Snøve O Jr,Rossi JJdoi
10.1186/gb-2006-7-8-231subject
Has Abstractpub_date
2006-01-01 00:00:00pages
231issue
8eissn
1474-7596issn
1474-760Xpii
gb-2006-7-8-231journal_volume
7pub_type
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