Abstract:
:The fraction of polyclonal caldesmon antibodies cross-reacting with rabbit skeletal troponin T are shown to compete with smooth muscle tropomyosin for caldesmon and troponin T, as revealed by ELISA method. The epitope recognized by these antibodies was also found in Mr 77 kDa non-muscle caldesmon. These results provide functional confirmation for the suggestion that the regions of amino acid sequence homology in caldesmon isoforms and troponin T belong to the tropomyosin binding sites.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Birukov KG,Shirinsky VP,Vorotnikov AV,Gusev NBdoi
10.1016/0014-5793(90)80206-xsubject
Has Abstractpub_date
1990-03-26 00:00:00pages
263-5issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(90)80206-Xjournal_volume
262pub_type
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