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Association between sperm autoantibodies and enhanced embryo implantation rates during in vitro fertilization.

Abstract：

:Previous investigations have demonstrated the propensity of strong IgA-class sperm autoantibodies to impede fertilization. However, because there has not been a general consensus on this issue, the aim of this retrospective analysis was to focus on the effects of different levels of IgA-class antibodies on each stage of the IVF procedure. This study has confirmed that high level IgA class antibodies significantly reduce fertilization rates but, unexpectedly, also has shown a very significant improvement in embryo implantation rates in patients with weak to moderate antibody levels. Interlaboratory prospective collaborative studies are being planned to test this preliminary observation more stringently.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Clarke GN

doi

10.1016/j.fertnstert.2006.02.089

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

753-4

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(06)00954-X

journal_volume

86

pub_type

杂志文章

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