Expression of IL-1beta, IL-1 receptor type I and IL-1 receptor antagonist in human aortic smooth muscle cells: effects of all-trans-retinoic acid.

abstract：:We investigated the possible interference of smooth muscle cells with monocyte response to LDL as well as with their adhesion and transmigration in a coculture of porcine endothelial and smooth muscle cells. Lysophosphatidylcholine (LPC), a component of oxidized LDL (oxLDL), stimulated the adhesion of THP-1 cells to e...

journal_title：Journal of vascular research

authors： Kinard F,Jaworski K,Sergent-Engelen T,Goldstein D,Van Veldhoven PP,Holvoet P,Trouet A,Schneider YJ,Remacle C

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Controversial reports on prolactin receptors (PRL-R), the long and short form, on endothelial cells (EC) may be explained by the choice of EC derived from the micro- and macrovascular bed of either endocrine and non-endocrine organs. METHODS:We studied here PRL-R expression in organs [bovine corpus luteum (...

journal_title：Journal of vascular research

authors： Ricken AM,Traenkner A,Merkwitz C,Hummitzsch K,Grosche J,Spanel-Borowski K

更新日期：2007-01-01 00:00:00

abstract：:In segments of rabbit basilar artery (BA) platelet-activating factor (PAF) initiated a concentration-dependent transitory contraction which was unaffected by indomethacin or nordihydroguaiaretic acid (NDGA). N omega-nitro-L-arginine (NLA) did not change the magnitude of PAF-induced contraction, but in the presence of ...

journal_title：Journal of vascular research

authors： Akopov SE,Sercombe R,Seylaz J

更新日期：1995-01-01 00:00:00

abstract：:The effects of the close arterial infusion of histamine upon the microcirculation of facial and nasal tissues were examined in dogs. Blood flow through arteriovenous anastomoses (AVA flow), capillaries (CAP flow) and collaterals (COL flow) were determined by electromagnetic flowmetry and the tracer-microsphere techniq...

journal_title：Journal of vascular research

authors： Bari F,Ariwodola JO,Pleschka K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Low birth weight (LBW) is associated with increased risk of type 2 diabetes and cardiovascular disease. We studied endothelial function and insulin sensitivity in young men with LBW (n = 22) and controls (n = 22). METHODS:Insulin sensitivity and endothelial function was studied with venous occlusion plethys...

journal_title：Journal of vascular research

authors： Sonne MP,Højbjerre L,Alibegovic AC,Vaag A,Stallknecht B,Dela F

更新日期：2010-01-01 00:00:00

abstract：:We evaluated the effects of a simulated workday of prolonged sitting on blood pressure (BP) and pulse wave velocity (PWV) and examined whether posture (seated vs. supine) affected responses. Participants (n = 25) were adults, with overweight/obesity and elevated BP, and performed seated desk work for 7.5 h. BP and PWV...

journal_title：Journal of vascular research

authors： Alansare AB,Kowalsky RJ,Jones MA,Perdomo SJ,Stoner L,Gibbs BB

更新日期：2020-01-01 00:00:00

abstract：:This study utilised catecholamine fluorescence histochemistry, multiple-labelling immunohistochemistry and retrograde axonal transport to determine the distribution and neuropeptide content of sympathetic neurons innervating veins in the dorsal skin of the guinea pig pinna. There was a dense plexus of sympathetic axon...

journal_title：Journal of vascular research

authors： Morris JL

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Vasomotion consists in cyclic oscillations of the arterial diameter induced by the synchronized activity of the smooth muscle cells. So far, contradictory results have emerged in the literature about the role of the endothelium in the onset and maintenance of vasomotion. Here our aim is to understan...

journal_title：Journal of vascular research

authors： Seppey D,Sauser R,Koenigsberger M,Bény JL,Meister JJ

更新日期：2008-01-01 00:00:00

abstract：:The proliferation of vascular smooth muscle cells (VSMC) plays a significant part in both the developing atherosclerotic lesion and in restenosis. Heparin has been widely reported to inhibit the growth of VSMC in culture and intimal VSMC in some animal models of vascular hyperplasia. Clinical trials with heparin, howe...

journal_title：Journal of vascular research

authors： Underwood PA,Mitchell SM,Whitelock JM

更新日期：1998-11-01 00:00:00

abstract：:The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasoconstriction of the femoral vascular bed is considerably greater at a co...

journal_title：Journal of vascular research

authors： Kartamyshev SP,Balashov SA,Melkumyants AM

更新日期：2007-01-01 00:00:00

abstract：:The mechanosensitive nonselective cation channel (NSC(MS)) is a key player in vascular myogenic contraction. The functional channel density and pressure sensitivity of NSC(MS) in vascular myocytes were compared between pulmonary and systemic arteries (coronary, mesenteric and cerebral arteries) in the rabbit. In cell-...

journal_title：Journal of vascular research

authors： Park KS,Lee HA,Earm KH,Ko JH,Earm YE,Kim SJ

更新日期：2006-01-01 00:00:00

abstract：:In the present study, we investigated the actions of calmodulin (CaM) and CaM-dependent protein kinase II (CaMK-II) on the L-type Ca2+ currents (ICa(L)) of cultured vascular smooth muscle (VSM) cells (A7r5 cell line), using the whole-cell voltage clamp method. The peak IBa (Ca2+ channel using 5 mM Ba2+ as charge carri...

journal_title：Journal of vascular research

authors： Sunagawa M,Yokoshiki H,Seki T,Sperelakis N

更新日期：1998-09-01 00:00:00

abstract：:Intima-media thickening (IMT) of the carotid artery, a form of vascular remodeling, correlates well with coronary artery disease risk in humans. Vascular remodeling in response to blood flow is a complex process that critically involves altered cell matrix interactions. To gain insight into these events, we performed ...

journal_title：Journal of vascular research

authors： Korshunov VA,Solomatina MA,Plekhanova OS,Parfyonova YV,Tkachuk VA,Berk BC

更新日期：2004-11-01 00:00:00

abstract：:The localization of dopamine receptor subtypes in the rabbit pulmonary circulation was investigated by using combined radioligand binding and light microscope autoradiography techniques. Dopamine D1-like receptors, probably belonging to the dopamine D1 receptor subtype, were demonstrated in sections of rabbit lung usi...

journal_title：Journal of vascular research

authors： Kobayashi Y,Ricci A,Amenta F,Cavallotti C,Hattori K

更新日期：1995-05-01 00:00:00

abstract：:Dietary flavonoids are thought to protect against cardiovascular disease. We have studied the effects of bioactive isoflavone metabolites on hyperlipidemia, endothelial dysfunction and the development of atherosclerotic lesions in apolipoprotein E-deficient (apoE(0)) mice fed a Western high-fat diet. Supplementation w...

journal_title：Journal of vascular research

authors： Jiang F,Jones GT,Husband AJ,Dusting GJ

更新日期：2003-05-01 00:00:00

abstract：INTRODUCTION:This study aimed to investigate whether epigallocatechin-3-gallate (EGCG) shows antioxidant activity against angiotensin II (Ang II)-induced human umbilical vein endothelial cell (HUVEC) apoptosis. MATERIALS AND METHODS:The viability of HUVECs was revealed by MTT and LDH assay. The cell apoptosis was dete...

journal_title：Journal of vascular research

authors： Zhou X,Liang L,Zhao Y,Zhang H

更新日期：2017-01-01 00:00:00

abstract：:In coronary artery diseases, cigarette smoking is a risk factor and the endothelin system plays a key role in the pathogenesis. This study was to examine if dimethylsulfoxide-soluble smoke particles (DSP) upregulate endothelin type-B (ETB) receptors in the coronary artery and investigate the mechanism. The isolated ra...

journal_title：Journal of vascular research

authors： Huang LH,Zhang PA,He JY,Liu J,Cao YX

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Angiopoietin-like protein 3 (ANGPTL3) is a liver-derived plasma protein that modulates plasma triglyceride clearance, angiogenesis and atherosclerosis in experimental models. So far, no study has examined its role in atherosclerosis in human subjects. We evaluated the possible association between plasma ANGP...

journal_title：Journal of vascular research

authors： Hatsuda S,Shoji T,Shinohara K,Kimoto E,Mori K,Fukumoto S,Koyama H,Emoto M,Nishizawa Y

更新日期：2007-01-01 00:00:00

abstract：:Endothelin-1 (ET-1), a vasoconstrictor peptide produced by endothelial and vascular smooth muscle cells (VSMC) might play a role in vascular remodelling. To investigate the proposed 'mitogenic' potential of ET-1, we examined the effects of chronic exposure of VSMC to ET-1 on cell cycle, growth/proliferation and differ...

journal_title：Journal of vascular research

authors： Hahn AW,Regenass S,Resink TJ,Kern F,Bühler FR

更新日期：1993-07-01 00:00:00

abstract：:The pH has marked effects on the blood flow in several vascular beds but the underlying mechanisms remain incompletely understood. It is still not agreed, for example, whether it is the fall in extracellular pH or intracellular pH that is responsible for changes in tone resulting from hypercapnic acidosis. The issue h...

journal_title：Journal of vascular research

authors： Aalkjaer C,Poston L

更新日期：1996-09-01 00:00:00

abstract：:Neointima formation participates in the pathophysiology of atherosclerosis and restenosis. Proliferation and migration of vascular smooth muscle cells (VSMC) are initial responses to vascular injury. The aim of the present study was to assess the effect of gliotoxin, an inhibitor of nuclear factor (NF)-kappaB, on migr...

journal_title：Journal of vascular research

authors： Pozo M,Izquierdo MC,de Nicolás R,Egido J,Ortiz A,González-Cabrero J

更新日期：2009-01-01 00:00:00

abstract：:The circadian clock is rhythmically expressed in blood vessels, but the interaction between the circadian clock and disturbed blood flow remains unclear. We examined the relationships between BMAL1 and CLOCK and 2 regulators of endothelial function, AKT1 and endothelial nitric oxide synthase (eNOS), in vascular region...

journal_title：Journal of vascular research

authors： Shang X,Pati P,Anea CB,Fulton DJ,Rudic RD

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:It has been reported that smoking is one of the strongest positive risk factors for abdominal aortic aneurysms (AAAs). Although many studies have been directed to decipher the effect of smoking on AAA, its effect on macrophage activation has not yet been explored. OBJECTIVES:We have reported the importance ...

journal_title：Journal of vascular research

authors： Igari K,Kelly MJ,Yamanouchi D

更新日期：2019-01-01 00:00:00

abstract：:The contribution of ATP-sensitive potassium channel (KATP channel) blockade in the vasoconstriction produced by vasopressin was studied. All experiments were performed using rat thoracic aorta cut in 4-mm rings, denuded from their endothelium and mounted into 20-ml organ baths. Glibenclamide (0.01-10 microM), a KATP c...

journal_title：Journal of vascular research

authors： Dumont E,Lamontagne D

更新日期：1995-03-01 00:00:00

abstract：:Proper development of the vascular system as one of the earliest and most critical steps during vertebrate embryogenesis is ensured by the exact spatial and temporal control of gene expression in cells forming the vessel network. Whereas the regulation of vascular system development is well elucidated on the level of ...

journal_title：Journal of vascular research

authors： Bruderer M,Alini M,Stoddart MJ

更新日期：2013-01-01 00:00:00

abstract：:Atherosclerosis underlies late occlusion of human saphenous vein (HSV) coronary artery bypass grafts. Monocyte infiltration is implicated, but its mechanisms are unclear given that HSV normally expresses the ICAM-1 but not the VCAM-1 adhesion molecule. To define the mechanisms underlying monocyte adhesion, samples of ...

journal_title：Journal of vascular research

authors： Crook MF,Southgate KM,Newby AC

更新日期：2002-05-01 00:00:00

abstract：:The release of cytokines and chemokines from activated immune-competent cells plays a crucial role in determining the pathology of the atherogenic progress. We investigated the effect of bacterial lipopolysaccharide (LPS) on cytokine/chemokine expression in carotid lesions and normal renal arteries. The lesions or ren...

journal_title：Journal of vascular research

authors： Jatta K,Wågsäter D,Norgren L,Stenberg B,Sirsjö A

更新日期：2005-05-01 00:00:00

abstract：UNLABELLED:Nitric oxide (NO) and cyclooxygenase (COX) derived prostaglandins (PGs) are involved in vascular homeostasis. Contradictory results have been obtained in previous studies on the putative 'cross-talk' between these two pathways. Our aim was to evaluate the interaction between NO and PG release in human microv...

journal_title：Journal of vascular research

authors： Vassalle C,Domenici C,Lubrano V,L'Abbate A

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:To determine: (1) whether variables of a pulse wave form analysis of ocular microcirculation shown by laser speckle flowgraphy (LSFG) correlate with left ventricular (LV) systolic dysfunction and (2) whether these variables correlate with LV diastolic dysfunction in subjects without LV systolic dysfunction as a...

journal_title：Journal of vascular research

authors： Shiba T,Takahashi M,Matsumoto T,Hori Y

更新日期：2018-01-01 00:00:00

abstract：:Regulation of [Ca2+]i and modulation of the [Ca2+]i sensitivity of myosin phosphorylation in smooth muscles may involve phosphorylation of one or more proteins on tyrosine residues. We tested this hypothesis by measuring tyrosine phosphorylation of proteins extracted from swine carotid artery and separated by SDS gel ...

journal_title：Journal of vascular research

authors： Rembold CM,Weaver BA

更新日期：1997-01-01 00:00:00