Abstract：
:Ultram (tramadol HCL) was approved by the Food and Drug Administration in 1994 as a non-scheduled drug under the Controlled Substance Act. The non-scheduled status was contingent on the development and implementation of a comprehensive post-marketing surveillance program by an Independent Steering Committee external to Ortho-McNeil Pharmaceutical charged with monitoring abuse and recommending scheduling if unexpectedly high abuse occurred. The program developed by this committee was composed of a variety of studies, and the results of the first three years of the surveillance efforts revealed that the rate of Ultram abuse was low. At a meeting of the FDA in 1998 to reexamine the scheduling status of Ultram, it was recommended that the scope of the postmarketing surveillance program be broadened to include data on diversion. After a 1-year pilot study, by January 2002, a nationwide diversion survey was fully operational. This brief communication describes the experiences of this diversion study, and compares the findings on the diversion of Ultram and other tramadol HCL products with that of more widely abused drugs. Survey data suggest that the diversion of Ultram and other tramadol products is low, and overall, diversion investigators did not consider tramadol to be a problem in their respective jurisdictions.
journal_name
J Addict Disjournal_title
Journal of addictive diseasesauthors
Inciardi JA,Cicero TJ,Munoz A,Adams EH,Geller A,Senay EC,Woody GEdoi
10.1300/J069v25n02_08subject
Has Abstractpub_date
2006-01-01 00:00:00pages
53-8issue
2eissn
1055-0887issn
1545-0848journal_volume
25pub_type
杂志文章abstract：:Alcohol and illicit drugs affect neurons through various mechanisms and are detected by neuroimaging techniques. The optical coherence tomography device has just been used in research on substance use disorders. In this study, we compared the retinal nerve fiber layer (RNFL), the ganglion cell layer (GCL), the inner p...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2020.1776083
更新日期：2020-10-01 00:00:00
abstract：:A patient maintained on methadone for opioid-dependency developed recurrent syncope. Episodes occurred within hours after using cocaine, and were initially presumed secondary to seizure disorder. However, the patient subsequently suffered a cardiac arrest, and polymorphic ventricular tachycardia (torsade de pointes) w...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v24n01_05
更新日期：2005-01-01 00:00:00
abstract：:Background: Between 2005 and 2015, the prevalence of smoking among US adults has decreased for all age subgroups, except those aged 65 and older. Aim: In order to identify potential correlates of smoking behaviors in older adults, this research examined associations between age, smoking beliefs, and quitline utilizati...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2018.1521255
更新日期：2018-01-01 00:00:00
abstract：:Smoking-related illnesses are the leading causes of morbidity and mortality in Brazil. Despite a smoking prevalence of approximately 40%, there is limited national effort to reduce tobacco use in Brazil by means of public education and training of health care professionals to promote smoking education. In particular, ...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v18n01_03
更新日期：1999-01-01 00:00:00
abstract：:The AIDS epidemic has dramatically affected drug treatment programs, creating both an epidemiological crisis and a psychological one. A paramount question for treatment program staff is how to prevent patients from acquiring or spreading HIV. The health belief model has been useful in generating prevention approaches,...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v10n04_05
更新日期：1991-01-01 00:00:00
abstract：:Malingering of ADHD symptoms is a potential means of nonmedical use of prescription stimulants (NMUPS). The Subtle ADHD Malingering Screener (SAMS) provides a potential avenue for identification of symptom malingering. However, no real world evidence of this scale has been published to date. The goal of this study was...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2020.1732762
更新日期：2020-04-01 00:00:00
abstract：:An increasing percentage of women are U.S. Military Veterans. We review the substance misuse rates and comorbidities and the risk factors for and consequences of substance use among women Veterans. Women Veterans may have higher rates of substance misuse and comorbid psychiatric and medical disorders than male Veteran...
journal_title：Journal of addictive diseases
pub_type： 杂志文章,评审
doi：10.1080/10550887.2013.795465
更新日期：2013-01-01 00:00:00
abstract：:The Smoking Abstinence Expectancies Questionnaire is a quick and reliable scale assessing the expected consequences of short-term nicotine abstinence. The present study sought to translate the Smoking Abstinence Expectancies Questionnaire to Italian and assess its psychometric properties. A sample of 366 daily smokers...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2016.1251732
更新日期：2017-01-01 00:00:00
abstract：:Methamphetamine use has clearly reached epidemic proportions in large parts of the western and midwestern US. Because of the regional specificity of methamphetamine use, there is speculation that it may be a temporary problem and not a long-term public health problem. Unfortunately there are a number of factors that s...
journal_title：Journal of addictive diseases
pub_type： 杂志文章,评审
doi：10.1300/j069v21n01_02
更新日期：2002-01-01 00:00:00
abstract：:The smoking prevalence of medical faculty members has not been a subject of research as frequently as physicians and medical students. The objective of this study was to determine the status of tobacco use and some attitudes among medical faculty members of a Northern Cyprus university. The data were collected by a qu...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2020.1730129
更新日期：2020-04-01 00:00:00
abstract：:This study investigated the influence of tobacco use on postoperative narcotic requirements of female patients following pelvic surgery. The history of tobacco use was taken by telephone survey, and the amount of postoperative narcotic used was obtained from a retrospective review of the patients' hospital charts. Pos...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v19n04_01
更新日期：2000-01-01 00:00:00
abstract：:Despite long-standing recommendations that patients with substance use disorders receive primary care, only one-half of patients with substance use disorders receive such care. This article presents a conceptual model to facilitate the transition of patients from addiction treatment to primary care. A narrative review...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2014.969602
更新日期：2014-01-01 00:00:00
abstract：:Employment is a key functioning index in addiction services and consistently emerges as a goal among individuals in recovery. Research on the employment status in the addiction field has focused on treatment populations or welfare recipients; little is known of employment rates or their predictors among individuals in...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2012.694604
更新日期：2012-01-01 00:00:00
abstract：:The following paper is the result of a retrospective study of clinical case files of legal professionals treated for substance-related and co-occurring psychiatric disorders at a recovery center specializing in the care of impaired professionals. Attorneys traditionally differ from healthcare professionals in two impo...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v23n01_05
更新日期：2004-01-01 00:00:00
abstract：:The comorbidity between substance-use disorders and borderline personality disorder (SUD-BPD) with other psychiatric disorders has been little studied. A total of 937 drug-dependent patients were evaluated using semistructured interviews and 13.7% were SUD-BPD patients. After multivariate analysis, gender, Affective D...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2016.1274594
更新日期：2017-04-01 00:00:00
abstract：:Tobacco dependence is prevalent among alcohol dependent patients, and causes increased morbidity and mortality. Concurrent treatment for these disorders may be advantageous, but there are concerns about adverse effects on alcohol treatment outcomes. The Timing of Alcohol and Smoking Cessation (TASC) Study is a randomi...
journal_title：Journal of addictive diseases
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1300/j069v22n04_08
更新日期：2003-01-01 00:00:00
abstract：:In an attempt to reduce homelessness and substance abuse, Chicago graduates of short-term inpatient substance abuse programs who lacked domiciles were placed into one of three conditions: (1) a case management only intervention (n = 96), (2) a case management with supported housing intervention (n = 136), or (3) a con...
journal_title：Journal of addictive diseases
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1300/j069v14n04_01
更新日期：1995-01-01 00:00:00
abstract：:The first drinking experience has been suggested as an important point in etiological processes associated with alcohol use and abuse. In this study, initial drinking experiences were assessed among populations of alcoholics, problem drinkers, and non-problem drinkers. Results showed that the alcoholics and problem dr...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v10n03_04
更新日期：1991-01-01 00:00:00
abstract：:In this paper we report preliminary treatment outcome findings for the first 16 substance abuse patients who volunteered and qualified for a 12-week research-treatment program. Eight patients were exposed to a high-structure, behaviorally-oriented (HSB) individual counseling style, while the remaining eight were expos...
journal_title：Journal of addictive diseases
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1300/J069v16n03_06
更新日期：1997-01-01 00:00:00
abstract：:Using a sample of 453 veterans who received substance abuse treatment and were randomly assigned to case management and non-case management, this study examined both proximal (aftercare participation) and distal (severity of legal problems) measures of treatment outcomes. Multivariate analyses reveal that case-managed...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v21n04_04
更新日期：2002-01-01 00:00:00
abstract：:Smoking is a leading cause of morbidity and premature mortality in the United States. The relationship between tobacco smoking and several forms of cancer, heart disease, stroke, chronic lung disease, and other medical diseases is well recognized and accepted. Recent epidemiological studies are now focusing on the lin...
journal_title：Journal of addictive diseases
pub_type： 杂志文章,评审
doi：10.1300/J069v26S01_02
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:This study examines the characteristics and roles of physicians practicing in methadone maintenance treatment programs (MTPs). METHODS:Physicians and clinic directors at 172 MTPs in the United States completed surveys. MTPs were selected for study participation based on their locations (large urban, urban, o...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v23n02_02
更新日期：2004-01-01 00:00:00
abstract：:This review examines current therapies of alcoholism and addresses the difficulties encountered in evaluating the result of integrating pharmaco- and psychosocial treatment of alcoholics. A variety of treatment modalities and goals, and factors influencing admission of alcoholics, exist in different countries creating...
journal_title：Journal of addictive diseases
pub_type： 杂志文章,评审
doi：10.1080/10550889709511144
更新日期：1997-01-01 00:00:00
abstract：:The non-medical use of prescription medications has been identified as a major public health problem among youth, although few longitudinal studies have examined non-medical use of prescription medications in the context of other drug use. Previous cross-sectional studies have shown gender and race differences in non-...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2016.1186413
更新日期：2016-10-01 00:00:00
abstract：:The current study examines the longitudinal relationship between anxiety disorders in general, specific phobia in particular, and subsequent-onset alcohol use disorders in an adult population-based sample. In addition, the authors explore whether the hypothesized associations vary by gender. Approximately 23 years of ...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2010.531667
更新日期：2011-01-01 00:00:00
abstract：:One measure of a substance's addictive risk is the proportion of users who become dependent. This study evaluates the lifetime and current risk of substance dependence among lifetime substance users' among trauma inpatients and provides a relative ranking of addictive risk among the substances. Data on use of 8 substa...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/j069v26n01_09
更新日期：2007-01-01 00:00:00
abstract：:The authors investigated whether patients receiving buprenorphine maintenance treatment (BMT) will have corrected QT (QTc) prolongation after taking buprenorphine for an extended period of time. They also compared QTc prolongation for patients in methadone maintenance treatment (MMT) versus BMT to determine which medi...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2013.824333
更新日期：2013-01-01 00:00:00
abstract：:Although sleep has been extensively studied in substance related disorders, it has yet to be examined as thoroughly in gambling-related disorders. The purpose of this study is to examine the relationship between gambling severity and sleep disturbances in a sample of non-treatment seeking gamblers (N = 96) using the P...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2011.642754
更新日期：2012-01-01 00:00:00
abstract：:Introduction: Anxiety sensitivity (AS) is the fear of anxiety symptoms related to physical, cognitive, and social concerns. AS has been implicated in amplifying negative emotional states and maintaining smoking behavior. Aims: The current cross-sectional study evaluated the lower-order facets of AS (Physical, Cognitiv...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1080/10550887.2018.1542239
更新日期：2018-01-01 00:00:00
abstract：:This pilot study evaluated the association between substance abuse outcome and putative protective factors in sons of alcoholic fathers. A battery of questionnaires was anonymously self-administered to 24 sons of alcoholic fathers ages 16-19 years to identify relationships between alcohol and/or drug abuse and factors...
journal_title：Journal of addictive diseases
pub_type： 杂志文章
doi：10.1300/J069v14n02_06
更新日期：1995-01-01 00:00:00
