Abstract:
BACKGROUND:Depletion of liver glycogen stores and subsequent hypoglycaemia is one of the unresolved features in endotoxaemia. The aim of this study was to elucidate the effect of L-arginine treatment on the glucose requirement and impending liver damage during the hypoglycaemic period of endotoxaemia. METHODS:Sixty-three of 98 male Wistar rats were assigned equally to one of three groups and received saline as control, L-arginine as selective nitric oxide donor or N(G)-nitro-L-arginine methyl ester for non-selective inhibition of nitric oxide production 1 h before endotoxin injection. At 2, 4 and 6 h following endotoxin, blood and liver samples were collected. Plasma nitrite plus nitrate, glucose, insulin and glucagon concentrations and total liver-reduced glutathione were measured. Hepatocellular glycogen content and liver damage were assessed simultaneously by histological quantification. An additional seven rats were allocated to each group and subjected to i.v. glucose tolerance test during the hypoglycaemic period. RESULTS:Increased levels of endogenousglutathione (P = 0.003) and excess nitric oxide (P = 0.002) apparently protected the liver from endotoxin-induced injury by preserving the optimum glucose consumption rate, insulin/glucagon ratio and liver glycogen in L-arginine-plus-endotoxin-treated group. Furthermore, expected hypoglycaemic period was not observed in these animals. CONCLUSION:Exogenous L-arginine prevented the excessive liver glycogen release without inhibiting glucose consumption while decreasing hepatic injury during the expected hypoglycaemic phase of endotoxaemia.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Engin A,Zemheri M,Bukan N,Memiş Ldoi
10.1111/j.1445-2197.2006.03763.xsubject
Has Abstractpub_date
2006-06-01 00:00:00pages
512-7issue
6eissn
1445-1433issn
1445-2197pii
ANSjournal_volume
76pub_type
杂志文章abstract:BACKGROUND:This review examines the surgical management of acute superior mesenteric artery (SMA) occlusion and the impact of interventional radiology techniques. METHODS:Eight consecutive patients with SMA occlusion were treated at the Lismore Base Hospital, Lismore, NSW, Australia, from 1996 through to 2001 and of t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1046/j.1445-2197.2002.02289.x
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Scaphoid fracture is a common carpal fracture, and its treatment often requires fixation devices. This study aimed to investigate the efficacy and safety of a memory alloy nail-feet-fixation (MANFF) device in treating scaphoid fractures. METHODS:Sixty-six patients with closed scaphoid fractures were treated...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13641
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Surgical therapy for the thoracic aorta carries a high morbidity and mortality. Endovascular therapy for aneurysms and its adaptation to the thoracic aorta over the past 10 years is an exciting advance. This is a retrospective review of endovascular grafting of the thoracic aorta during the past decade at Ro...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04293.x
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:For proven gastro-oesophageal reflux disease, partial fundoplication is considered as effective as Nissen, but with fewer side effects. The aim of this meta-analysis was to compare the effect of laparoscopic partial fundoplication (LPF) with laparoscopic Nissen fundoplication (LNF). METHODS:Extensive medica...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,meta分析
doi:10.1111/j.1445-2197.2010.05637.x
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Intraoperative blood loss and transfusion are known determinants of mortality and morbidity of elective abdominal aortic aneurysm (AAA) repair. The present study analysed the pattern of blood loss and transfusion and evaluated the risk factors of blood loss during open repair of infrarenal AAA. METHODS:Bloo...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03117.x
更新日期:2004-08-01 00:00:00
abstract::Susan Nixon died in 1881 following a surgical error. Her surgeon, Dr W. E. Warren, excised a normal 7-month gravid uterus under the misapprehension that he was removing a tubular pregnancy. It is believed that Mrs Nixon was the first woman in Australia to have an abdominal hysterectomy and the second to have a live Ca...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1445-2197.2005.03501.x
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND: The purpose of credentialing is to ensure that clinicians provide safe, high-quality health-care services in accordance with good practice and legal requirements. This review assessed the institutional credentialing processes and governance structures required to support credentialing processes at an insti...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2012.06115.x
更新日期:2012-07-01 00:00:00
abstract:INTRODUCTION:Outcomes are reviewed with traumatic brain injury (TBI) involving intracranial haematomata (ICH) with patients in rural and remote areas of South Australia and adjacent states. Patients were referred to the Royal Adelaide Hospital (RAH), a level 1 trauma centre with a major neurosurgical service. METHOD:F...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13583
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:In elective colorectal resections, the patient's preoperative social situation may play a significant role in delaying their discharge from hospital. The aim of this study was to identify which preoperative factors are associated with non-medical reasons for a delay in discharge and prolonged length of stay ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2010.05587.x
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Although current progress in surgical instruments is oriented towards stapler devices, minimally invasive instrumentation and advanced cautery tools, it definitely seems intriguing to determine what instruments were used in antiquity and to appraise their use. Most adequate information can be retrieved from ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13027
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Bulbourethral syringocele is an uncommon and under-diagnosed condition most commonly seen in the paediatric population, although there is increasing recognition in adults. Due to the difficulty in diagnosis, we report our experience of urethral syringocele in a quaternary paediatric hospital, with differing ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.15039
更新日期:2019-06-01 00:00:00
abstract::Both chemical and mechanical methods of prophylaxis have reduced the incidence of thromboembolic complications following total knee replacement (TKR). Only a few studies have shown that mobilization on the first post-operative day further reduces the incidence of thromboembolic phenomena. We conducted a prospective st...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.04982.x
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:To prevent postoperative hypoparathyroidism following total thyroidectomy, the parathyroid glands are preserved in situ and/or resected or devascularized parathyroid glands are autotransplanted. A retrospective investigation was conducted utilizing biochemical and specific endocrine assessments to evaluate t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03435.x
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study is to determine the safety of a one-incision technique for distal biceps repair with modified repair entry point in regards to the distance from the posterior interosseous nerve (PIN). Secondly, we present the clinical results of patients having undergone this procedure. METHODS:Te...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13684
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:In Australia, robotic-assisted radical prostatectomy (RARP) has steadily replaced open and laparoscopic surgery in the management of localized prostate cancer. Given the increased cost of this technology, we aimed to compare the perioperative, pathological, oncological and functional outcomes as well as shor...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12602
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Malignant blue nevus, blue nevus-associated melanoma and blue nevus-like melanoma are all terms used to describe malignant melanomas arising from, in association with, or resembling blue nevi. This review is aimed at summarizing the available literature to reduce the confusion surrounding this rare malignanc...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.13946
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:The Pacific Island nation of Samoa faces a number of challenges in delivering surgical care. Our group aimed to identify the barriers and opportunities to improving the delivery of safe, affordable, timely surgical care in Samoa. METHODS:A mixed-methods approach was undertaken. The quantitative analysis use...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15295
更新日期:2019-06-18 00:00:00
abstract:BACKGROUND:Severe tracheal stenosis is a rare life-threatening condition that often requires early surgical intervention. The management of this anomaly has been associated with significant mortality and morbidity. We describe our experience with repair of this condition. METHODS:From 1986 to 2011, 20 patients underwe...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12132
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Quad bikes are a prominent cause of morbidity and mortality in Australia in both agriculture and recreation. This study describes the clinical and epidemiological characteristics of quad bike injuries at the Royal Darwin Hospital (RDH). METHODS:A retrospective review of the RDH Trauma Registry for all quad ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15631
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Most studies available on laparoscopic colorectal surgery focus on highly selected patient groups. The aim of the present study was to review short- and long-term outcome of everyday patients treated in a general surgery department. METHODS:Retrospective review was carried out of a prospective database of a...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03551.x
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to clarify the post-operative prognosis of pancreatic head cancer with pathologic portal vein (PV) or superior mesenteric vein (SMV) invasion. METHODS:From May 1995 to December 2009, preoperative, intra-operative and post-operative data from 276 patients who underwent pancreati...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12502
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:A proportion of patients with acute pancreatitis (AP) develop necrosis. Around a third will become infected, and this is associated with a significant requirement for intervention and support. We evaluated the burden of necrotizing pancreatitis (NP) in an Australian tertiary hospital with regards to morbidit...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13883
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Gastrointestinal (GI) complications after cardiac surgery are uncommon, but are associated with high morbidity and mortality as well as significant hospital resource utilization. METHODS:We analysed a prospectively collected database containing all adult cardiac surgery procedures performed from July 2001 t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12134
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Passage of flatus and stool represents a key milestone in recovery after colonic resections. Colorectal surgeons may hold varied expectations regarding recovery rates after left- versus right-sided colectomies, but there is currently little evidence to inform post-operative care. This study prospectively com...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1111/ans.13823
更新日期:2018-04-01 00:00:00
abstract::Carpal tunnel syndrome is a common condition affecting 1% of the population. Open carpal tunnel release is the most commonly performed procedure for this condition. About 70-90% of patients have good to excellent long-term outcomes with open carpal tunnel release. The remainder have poor outcomes. An understanding of ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2009.05175.x
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The volume of orthopaedic literature is increasing exponentially, becoming more widely scattered among journals. The rate of increase in orthopaedics is greater than other specialties. We aimed to identify the number of different journals an orthopaedic surgeon would need to read to stay up-to-date with curr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12902
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Mastectomy for breast cancer treatment and prophylaxis has improved survival for patients. The advantage of implant reconstruction post mastectomy is that it avoids an additional donor site with its associated morbidity, which post-mastectomy autologous reconstruction necessitates. However, the deficiency of...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2012.06313.x
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Surgical clerkships facilitate development of knowledge and competency, but their structure and content vary. Establishment of new medical schools and raising student numbers are new challenges to the provision of standardized surgical teaching across Australasian medical schools. A survey was conducted to i...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2010.05524.x
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Laparoscopic liver resection (LLR) is increasingly common worldwide but its suitability in patients with cirrhosis is not clearly defined. There are minimal data in the western literature on this topic and previous work has compared LLR to open hepatectomy rather than to LLR in non-cirrhotic patients. This s...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15745
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Sentinel node biopsy is an accurate method for staging the axilla in early (small) breast cancers. However, data for the role of this technique for large breast cancers remain limited. METHOD:From the Royal Adelaide Hospital Sentinel Node database and the SNAC trial database, 100 subjects were identified wi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12139
更新日期:2014-03-01 00:00:00