Abstract:
BACKGROUND:Functional analysis of the catfish genome will be useful for the identification of genes controlling traits of economic importance, especially innate disease resistance. However, this species lacks a platform for global gene expression profiling, so we designed a first generation high-density oligonucleotide microarray platform based on channel catfish EST sequences. This platform was used to profile gene expression in catfish spleens 2 h, 4 h, 8 h and 24 h after injection of lipopolysaccharide (LPS). RESULTS:In the spleen samples, 138 genes were significantly induced or repressed greater than 2-fold by LPS treatment. Real-time RT-PCR was used to verify the microarray results for nine selected genes representing different expression levels. The results from real-time RT-PCR were positively correlated (R2 = 0.87) with the results from the microarray. CONCLUSION:The first generation channel catfish microarray provided several candidate genes useful for further evaluation of immune response mechanisms in this species. This research will help us to better understand recognition of LPS by host cells and the LPS-signalling pathway in fish.
journal_name
BMC Genomicsjournal_title
BMC genomicsauthors
Li RW,Waldbieser GCdoi
10.1186/1471-2164-7-134subject
Has Abstractpub_date
2006-06-01 00:00:00pages
134issn
1471-2164pii
1471-2164-7-134journal_volume
7pub_type
杂志文章相关文献
BMC GENOMICS文献大全abstract:BACKGROUND:Bacteria in the genus Ruminococcus are ubiquitous members of the mammalian gastrointestinal tract. In particular, they are important in ruminants where they digest a wide range of plant cell wall polysaccharides. For example, Ruminococcus albus 7 is a primary cellulose degrader that produces acetate usable b...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-1066
更新日期:2014-12-04 00:00:00
abstract:BACKGROUND:Olfaction is a versatile sensory mechanism for detecting thousands of volatile odorants. Although molecular basis of odorant signaling is relatively well understood considerable gaps remain in the complete charting of all relevant gene products. To address this challenge, we applied RNAseq to four well-chara...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-2960-3
更新日期:2016-08-11 00:00:00
abstract:BACKGROUND:Galileo is one of three members of the P superfamily of DNA transposons. It was originally discovered in Drosophila buzzatii, in which three segregating chromosomal inversions were shown to have been generated by ectopic recombination between Galileo copies. Subsequently, Galileo was identified in six of 12 ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-15-792
更新日期:2014-09-13 00:00:00
abstract:BACKGROUND:Salmonella enterica is a significant foodborne pathogen, which can be transmitted via several distinct routes, and reports on acquisition of antimicrobial resistance (AMR) are increasing. To better understand the association between human Salmonella clinical isolates and the potential environmental/animal re...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-018-5137-4
更新日期:2018-11-06 00:00:00
abstract:BACKGROUND:The microsporidian Encephalitozoon cuniculi is an obligate intracellular eukaryotic pathogen with a small nuclear genome (2.9 Mbp) consisting of 11 chromosomes. Although each chromosome end is known to contain a single rDNA unit, the incomplete assembly of subtelomeric regions following sequencing of the gen...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1920-7
更新日期:2016-01-07 00:00:00
abstract:BACKGROUND:The use of RNAseq to resolve the transcriptional organization of an organism was established in recent years and also showed the complexity and dynamics of bacterial transcriptomes. The aim of this study was to comprehensively investigate the transcriptome of the industrially relevant amino acid producer and...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-14-888
更新日期:2013-12-17 00:00:00
abstract:BACKGROUND:Genomic characterization of rotavirus (RoV) has not been adopted at large-scale due to the complexity of obtaining sequences for all 11 segments, particularly when feces are used as starting material. METHODS:To overcome these limitations, we developed a novel RoV capture and genome sequencing method combin...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-017-3714-6
更新日期:2017-04-24 00:00:00
abstract::Following the publication of the original article [1], the authors reported an error in Fig. 2 of the PDF version of their article. ...
journal_title:BMC genomics
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12864-019-6419-1
更新日期:2019-12-31 00:00:00
abstract:BACKGROUND:Fungal pathogens of plants produce diverse repertoires of secondary metabolites, which have functions ranging from iron acquisition, defense against immune perturbation, to toxic assaults on the host. The wheat pathogen Zymoseptoria tritici causes Septoria tritici blotch, a foliar disease which is a signific...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-017-3969-y
更新日期:2017-08-17 00:00:00
abstract:BACKGROUND:Single Nucleotide Polymorphisms (SNPs) can be used as genetic markers for applications such as genetic diversity studies or genetic mapping. New technologies now allow genotyping hundreds to thousands of SNPs in a single reaction.In order to evaluate the potential of these technologies in pea, we selected a ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-11-468
更新日期:2010-08-11 00:00:00
abstract:BACKGROUND:The giant panda, one of the most primitive carnivores, is an endangered animal. Although it has been the subject of many interesting studies during recent years, little is known about its genome. In order to promote research on this genome, a bacterial artificial chromosome (BAC) library of the giant panda w...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-7-294
更新日期:2006-11-17 00:00:00
abstract:UNLABELLED:Transcription-induced chimerism, a mechanism involving the transcription and intergenic splicing of two consecutive genes, has recently been estimated to account for approximately 5% of the human transcriptome. Despite this prevalence, the regulation and function of these fused transcripts remains largely un...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-8-348
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Climate plays an essential role in forest health, and climate change may increase forest productivity losses due to abiotic and biotic stress. Increased temperature leads to the increased formation of ozone (O3). Ozone is formed by the interaction of sunlight, molecular oxygen and by the reactions of chemica...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-6549-5
更新日期:2020-02-14 00:00:00
abstract:BACKGROUND:Every year, substantial crop loss occurs globally, as a result of bacterial, fungal, parasite and viral infections in rice. Here, we present an in-depth investigation of the transcriptomic response to infection with the destructive bacterial pathogen Xanthomonas oryzae pv. oryzae(Xoo) in both resistant and s...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-14-93
更新日期:2013-02-12 00:00:00
abstract:BACKGROUND:Obesity and phenotypic traits associated with this condition exhibit significant heritability in natural populations of most organisms. While a number of genes and genetic pathways have been implicated to play a role in obesity associated traits, the genetic architecture that underlies the natural variation ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-11-297
更新日期:2010-05-11 00:00:00
abstract:BACKGROUND:Native cattle breeds are an important source of genetic variation because they might carry alleles that enable them to adapt to local environment and tough feeding conditions. Jiaxian Red, a Chinese native cattle breed, is reported to have originated from crossbreeding between taurine and indicine cattle; th...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-07340-0
更新日期:2021-01-09 00:00:00
abstract:BACKGROUND:Although primarily known as the site of ribosome subunit production, the nucleolus is involved in numerous and diverse cellular processes. Recent large-scale proteomics projects have identified thousands of human proteins that associate with the nucleolus. However, in most cases, we know neither the fraction...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-74
更新日期:2011-01-27 00:00:00
abstract:BACKGROUND:Sheath blight (SB), caused by Rhizoctonia solani, is a common rice disease worldwide. Currently, rice cultivars with robust resistance to R. solani are still lacking. To provide theoretic basis for molecular breeding of R. solani-resistant rice cultivars, the changes of transcriptome profiles in response to ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-6645-6
更新日期:2020-03-19 00:00:00
abstract:BACKGROUND:GLV-1h68 is an attenuated recombinant vaccinia virus (VACV) that selectively colonizes established human xenografts inducing their complete regression. RESULTS:Here, we explored xenograft/VACV/host interactions in vivo adopting organism-specific expression arrays and tumor cell/VACV in vitro comparing VACV ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-10-301
更新日期:2009-07-07 00:00:00
abstract:BACKGROUND:It is unclear whether improving feed efficiency by selection for low residual feed intake (RFI) compromises pigs' immunocompetence. Here, we aimed at investigating whether pig lines divergently selected for RFI had different inflammatory responses to lipopolysaccharide (LPS) exposure, regarding to clinical p...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-019-6127-x
更新日期:2019-10-11 00:00:00
abstract:BACKGROUND:Selenium (Se) is a trace element that occurs in proteins in the form of selenocysteine (Sec) and in tRNAs in the form of selenouridine (SeU). Selenophosphate synthetase (SelD) is required for both utilization traits. However, previous research also revealed SelDs in two organisms lacking Sec and SeU, suggest...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-9-251
更新日期:2008-05-29 00:00:00
abstract:BACKGROUND:Several global transcriptomic and proteomic approaches have been applied in order to obtain new molecular insights on skeletal myogenesis, but none has generated any specific data on glycogenome expression, and thus on the role of glycan structures in this process, despite the involvement of glycoconjugates ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-10-483
更新日期:2009-10-20 00:00:00
abstract:BACKGROUND:Maternal effects contribute to adaptive significance for shaping various phenotypes of many traits. Potential implications of maternal effects are the cause of expression diversity, but these effects on mRNA expression and alternative splicing (AS) have not been fully elucidated in hybrid animals. RESULTS:T...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-06866-7
更新日期:2020-07-02 00:00:00
abstract:BACKGROUND:Starch and protein are two major components of polished rice, and the amylose and protein contents affect eating and cooking qualities (ECQs). In the present study, genome-wide association study with high-quality re-sequencing data was performed for 10 ECQs in a panel of 227 non-glutinous rice accessions and...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-016-3000-z
更新日期:2016-08-20 00:00:00
abstract:BACKGROUND:Venomous animals incapacitate their prey using complex venoms that can contain hundreds of unique protein toxins. The realisation that many of these toxins may have pharmaceutical and insecticidal potential due to their remarkable potency and selectivity against target receptors has led to an explosion in th...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-10-375
更新日期:2009-08-13 00:00:00
abstract:BACKGROUND:Lateral gene transfer (LGT) is an important evolutionary process in microbial evolution. In sewage treatment plants, LGT of antibiotic resistance and xenobiotic degradation-related proteins has been suggested, but the role of LGT outside these processes is unknown. Microbial communities involved in Enhanced ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-015-1752-5
更新日期:2015-07-16 00:00:00
abstract:BACKGROUND:Miniature inverted repeat transposable element (MITE) is one type of transposable element (TE), which is largely found in eukaryotic genomes and involved in a wide variety of biological events. However, only few MITEs were proved to be currently active and their physiological function remains largely unknown...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-13-135
更新日期:2012-04-13 00:00:00
abstract:BACKGROUND:We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating the gene encoding a chimeric hexose transporter, Tm6*, into the genome of an hxt null yeast. Subsequently we transferred this respiratory phenotype in the presence of up to 50 g/L glucose to a yeast strai...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-9-365
更新日期:2008-07-31 00:00:00
abstract:BACKGROUND:Many transcripts have been generated due to the development of sequencing technologies, and lncRNA is an important type of transcript. Predicting lncRNAs from transcripts is a challenging and important task. Traditional experimental lncRNA prediction methods are time-consuming and labor-intensive. Efficient ...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/s12864-020-07237-y
更新日期:2020-12-17 00:00:00
abstract:BACKGROUND:Siraitia grosvenorii (Luohanguo) is an herbaceous perennial plant native to southern China and most prevalent in Guilin city. Its fruit contains a sweet, fleshy, edible pulp that is widely used in traditional Chinese medicine. The major bioactive constituents in the fruit extract are the cucurbitane-type tri...
journal_title:BMC genomics
pub_type: 杂志文章
doi:10.1186/1471-2164-12-343
更新日期:2011-07-05 00:00:00