Abstract:
OBJECTIVE:Data from placebo-controlled, randomized clinical trials conducted during the past few years resulted in critical re-evaluation of the overall health benefits of hormone therapy (HT) in women during the menopausal transition and thereafter. These data stimulated vigorous debate among experts and produced several position papers by North American and European authorities providing guidance on the use of HT. It is well known that cultural, geographic and ethnic differences influence the acceptance and risk perception of HT. Therefore, it was considered essential to present a position specifically relevant to Latin American countries. METHODS:A Latin American Expert Panel, convening in Salvador, Bahia, Brazil, obtained consensus on recommendations for HT that incorporated the findings of the most recently published reports. The panelists' opinions were surveyed by means of the Likert scale along five categories ranging from complete agreement to complete disagreement. RESULTS:The Panel presented 13 recommendations and considered three additional issues relevant to HT use. There was consensus that HT during the perimenopause and thereafter is warranted in Latin American women in particular for the management of vasomotor symptoms. HT may also be an option for osteoporosis prevention in women at significant risk, after evaluation of risks/benefits and after consideration of alternative therapies. HT should be individualized and prescribed at the lowest effective dose. CONCLUSIONS:The Panel concluded that HT remains a safe and effective treatment option for peri- and postmenopausal Latin American women.
journal_name
Maturitasjournal_title
Maturitasauthors
Maia H Jr,Albernaz MA,Baracat EC,Barbosa IC,Bossemeyer R,Bueno AH,Campos OG,Carranza-Lira S,Casas PF,Castro AM,de Lima GR,de Melo NR,Fernandes CE,González JS,Larrañaga FE,Siseles N,Uribe AM,Vilchez RM,Latin American Edoi
10.1016/j.maturitas.2006.03.009subject
Has Abstractpub_date
2006-08-20 00:00:00pages
5-13issue
1eissn
0378-5122issn
1873-4111pii
S0378-5122(06)00100-9journal_volume
55pub_type
共识发展会议,杂志文章,实务指引相关文献
MATURITAS文献大全abstract:OBJECTIVES:The purpose of this study was to investigate whether a previous fracture is a risk factor for fracture later in life and its association with tobacco smoking, menopausal age and the use of oral contraceptives. This is an epidemiological population study based on a questionnaire. A sample of 10000 women from ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(95)01024-6
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of vitamin K2 treatment for a year on spinal bone mineral density (BMD) in postmenopausal women, comparing with vitamin D3 hormone replacement therapy and to determine the factors which affect the efficacy of vitamin K2 therapy. SUBJECTS AND METHODS:Seventy-two postmenopausal women...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-5122(98)00114-5
更新日期:1999-01-04 00:00:00
abstract:OBJECTIVE:We analysed the risk factors for clinically diagnosed uterine fibroids in women attending menopause clinics in Italy. METHODS:Between 1997 and 2003 we conducted a large cross-sectional study on the characteristics of women around menopause attending a network of first-level outpatient menopause clinics in It...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2006.01.013
更新日期:2006-09-20 00:00:00
abstract:BACKGROUND/AIM:The aim of this study was to compare the role of quantitative ultrasonography (QUS) and dual energy X-ray absorptiometry (DEXA) in the assessment of osteoporosis. METHODS:From June 1999 to November 2001, 596 women who have not been diagnosed osteoporosis and without previous history of pathologic fractu...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(02)00036-1
更新日期:2002-06-25 00:00:00
abstract:OBJECTIVES:To analyze independently in men and women the incidence rate of and risk factors for hip fracture in a southern European population. Illiteracy, dementia, clinically significant depression and disability were factors to receive special emphasis. STUDY DESIGN:A community sample of 4803 individuals aged over ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2016.12.009
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:To describe the prevalence of hormone replacement therapy (HT) use by postmenopausal women doctors and doctors' wives in Italy and to explore the relationship between their personal characteristics and HT use. DESIGN:A total of 500 women doctors and 500 men doctors answering on behalf of their female partner...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2005.10.008
更新日期:2006-05-20 00:00:00
abstract::Since the launch in 2008 by the National Osteoporosis Guideline Group (NOGG), of guidance for the diagnosis and management of osteoporosis in postmenopausal women and older men in the UK there have been significant advances in risk assessment and treatment. These have been incorporated into an updated version of the g...
journal_title:Maturitas
pub_type: 杂志文章,实务指引
doi:10.1016/j.maturitas.2013.05.013
更新日期:2013-08-01 00:00:00
abstract::Two-thirds of patients with type 2 diabetes mellitus (T2DM) have arterial hypertension. Hypertension increases the incidence of both micro- and macrovascular complications in these patients, while the co-existence of these two major risk factors leads to a four-fold increased risk for cardiovascular disease (CVD) comp...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2018.03.013
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To determine the median age of natural menopause in United Arab Emirates women, the factors affecting that age and the prevalence of climacteric symptoms amongst those women. METHODS:A population-based survey was conducted on a community sample of United Arab Emirates women who had had natural menopause def...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(98)00010-3
更新日期:1998-06-17 00:00:00
abstract::The two most important risk factors for maintaining skeletal health are the bone mass obtained at skeletal maturity (peak bone mass) and the subsequent bone loss. Those women with a low peak bone mass and a rapid bone loss are thus at increased risk of developing osteoporosis in the future, and should be identified. T...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/0378-5122(90)90006-r
更新日期:1990-09-01 00:00:00
abstract::Hot flashes are a common complaint among women as they transition through menopause. This article reviews the evidence of lifestyle alterations for the amelioration of hot flashes including obesity, exercise, smoking, relaxation techniques, and acupuncture. Further randomized controlled trials regarding these lifestyl...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2011.12.006
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:The biological mechanisms associated with an inadequate response to treatment with bisphosphonates are not well known. This study investigates the association between circulating levels of sclerostin and estradiol with an inadequate clinical outcome to bisphosphonate therapy in women with postmenopausal os...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2015.08.007
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The physiological role of parathormone (PTH) in the maintenance of bone mass in humans has not been fully defined. The main objective of the present study was to evaluate basal and EDTA-stimulated PTH levels in young women (Group Y=30.9 years, N=7) and in women in late menopause (Group M=64.7 years, N=7) and ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2007.10.002
更新日期:2008-01-20 00:00:00
abstract:OBJECTIVES:Association studies between estrogen receptor alpha (ERalpha) gene polymorphisms and bone mineral density (BMD) have yielded inconsistent results. In the present study we evaluated the influence of XbaI and PvuII ERalpha gene polymorphisms on BMD, biochemical markers, rates of bone loss and the response to e...
journal_title:Maturitas
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.maturitas.2005.07.007
更新日期:2006-03-20 00:00:00
abstract::In the past decade, the leading international cardiology societies have released statements that emphasize the importance of sex-specific reporting of the findings of clinical trials in cardiovascular research. To find out whether this has led to improvement, we compared sex-specific reporting of efficacy and safety o...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2020.09.007
更新日期:2021-02-01 00:00:00
abstract::There are few prospective data on temporal trends in overall sitting time for different domains of sitting. This study examined time trends over 6 years in total and domain-specific sitting time in mid-age Australian men and women. Self-report data from 5246 participants in four survey waves (2007, 2009, 2011, 2013) o...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2018.08.006
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:This paper aims to report the methodology of a study of a cohort of middle-aged women in Taiwan, their age at menopause, and related factors and prevalence of menopausal symptoms, and to examine the relationships between symptoms and sociodemographic variables. METHODS:An epidemiological study of neuropsych...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(01)00193-1
更新日期:2001-08-25 00:00:00
abstract::The aim of this trial was to study the vaginal absorption of oestriol and to investigate whether morning rather than evening oestriol administration would produce different plasma oestriol patterns. The influence of food intake on plasma oestriol levels was also investigated. Nine post-menopausal women were given 0.5 ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(86)90031-9
更新日期:1986-10-01 00:00:00
abstract::Examining such terms as climacteric or menopause and utilizing supportive historical data, an attempt is made to trace the development of these concepts, their time of inception and their spread. It is suggested that the persistence of popular terminology of the climacteric, especially in England, until late in the la...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/0378-5122(81)90013-x
更新日期:1981-03-01 00:00:00
abstract:INTRODUCTION:Strategies in case of high risk of breast cancer in BRCA1/2 mutation carriers are either intensive breast cancer screening or risk-reducing mastectomy (RRM). Both options have a high physical and psychosexual impact. The aim of this study is to investigate who chooses when to undergo RRM. METHODS:BRCA1/2 ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2013.10.017
更新日期:2014-02-01 00:00:00
abstract::In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2005.02.015
更新日期:2005-05-16 00:00:00
abstract::The recreational use of methamphetamine (METH, or ice) is a global burden. It pervades and plagues contemporary society; it has been estimated that there are up to 35 million users worldwide. METH is a highly addictive psychotropic compound which acts on the central nervous system, and chronic use can induce psychotic...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2018.12.003
更新日期:2019-03-01 00:00:00
abstract::Androgen insensitivity syndrome (AIS) is one of the most common sexual developmental disorders. According to the grade of the remaining androgen receptor (AR) function, AIS is classified as complete (CAIS), partial (PAIS) or mild (MAIS). In CAIS, the prevalence of germ cell tumours is increased compared with the gener...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2019.06.004
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:The effects of supplemental testosterone on cognition, mood and wellbeing in ageing men are unclear. This study aimed to assess the effect of 12-months of oral testosterone supplementation on cognitive function, mood and quality of life in elderly men with low-normal gonadal status, not specifically selected...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.maturitas.2004.05.002
更新日期:2005-02-14 00:00:00
abstract::This is a scoping review of the notions of authenticity and citizenship in the context of understanding dementia. Authenticity suggests being true to yourself. Social citizenship suggests engagement, relationships and rights. The literature which links authenticity to dementia is scanty, albeit the notion suggests num...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:10.1016/j.maturitas.2019.04.001
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:The effects of hormone replacement therapy on cardiovascular risk factors in postmenopausal women with non-insulin dependent diabetes mellitus (type II diabetes) is uncertain. METHODS:The effects of estrogen replacement therapy (ERT, conjugated equine estrogen0.625mg orally daily), combined estrogen and con...
journal_title:Maturitas
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-5122(99)00112-7
更新日期:2000-03-31 00:00:00
abstract:OBJECTIVES:An internet survey was performed to obtain data on the current use in Belgium of hormone replacement therapy and alternative treatments for the alleviation of menopausal symptoms. A supplementary aim was to assess the use of opt-in internet opinion panels (TalkToChange, http://www.talktochange.com, and GMI, ...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2016.04.018
更新日期:2016-08-01 00:00:00
abstract:AIMS:Women in the West can now expect to live one third of their life in a postmenopausal state, and consequently in a state of estrogen deficiency. This can have a number of consequences, and many women suffer vasomotor symptoms during the climacteric. Estrogen deficiency can also result in changes to the skin, hair, ...
journal_title:Maturitas
pub_type: 杂志文章,评审
doi:
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:The aim of this prospective 3-year clinical study was to examine the effect of hormone replacement therapy (HRT) on uterine fibroid growth among postmenopausal women. METHODS:Thirty-seven postmenopausal women with uterine solitary fibroids were recruited randomly for HRT in a 3-year program. All participants...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/s0378-5122(02)00159-7
更新日期:2002-09-30 00:00:00
abstract:INTRODUCTION:The use of menopausal hormone therapy (MHT) has decreased in many countries in the past 10 years. This is a consequence of the initial publication of the results of the Women's Health Initiative (WHI) randomized trial of estrogen plus progestin. In various countries, further studies then analyzed the incid...
journal_title:Maturitas
pub_type: 杂志文章
doi:10.1016/j.maturitas.2015.11.010
更新日期:2016-02-01 00:00:00