Genetic diversity and exotoxin A production of group A streptococci causing sepsis.

Abstract:

:The M protein and streptococcus pyrogenic exotoxin (SPE A) are important virulence factors in group A streptococci (GAS) infections. The emm types of GAS strains isolated from patients with sepsis were determined by sequencing the 5' N-terminus of the emm gene, encoding the M protein, and clonality analysis using pulsed-field gel electrophoresis. The presence of speA and production of SPE A were also examined. There were no predominant GAS clones. The emm genotypes were variable, and the most common genotype was emm13 (17.9%). The production prevalence of SPE A was 21.4%. The low mortality rate (7.1%) of GAS sepsis might be attributable to the low incidence of virulent strains such as emm1 (10.7%) and emm3 (7.1%), as well as to low production rate of SPE A.

journal_name

J Korean Med Sci

authors

Koh EH,Lee NY,Kim EC,Kim S

doi

10.3346/jkms.2006.21.2.193

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

193-8

issue

2

eissn

1011-8934

issn

1598-6357

pii

200604193

journal_volume

21

pub_type

杂志文章
  • A case of human cyclosporiasis causing traveler's diarrhea after visiting Indonesia.

    abstract::This is the first case of human cyclosporiasis reported in Korea. We detected the oocyst of Cyclospora cayetanensis from a 14-yr old girl who complained of persistent diarrhea after traveling to Indonesia. Round oocysts sized about 8 to 9 m with wrinkle on the wall were found in modified acid fast stained stool specim...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.5.738

    authors: Yu JR,Sohn WM

    更新日期:2003-10-01 00:00:00

  • A clinicopathological study of unsuspected carcinoma of the gallbladder.

    abstract::We investigated the incidence of unsuspected gallbladder (GB) carcinomas in a total of 527 consecutive GB specimens resected for benign biliary disease and their clinicopathological features. The GBs were examined microscopically using stepwise tissue sections at 5 mm interval. Clinical and pathological findings were ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1997.12.6.519

    authors: Kwon SY,Chang HJ

    更新日期:1997-12-01 00:00:00

  • Heart Rate Change While Drowsy Driving.

    abstract::Heart rate (HR) change during sleepy driving has never been investigated. Healthy volunteers who planned to drive a long distance were recruited and monitored with a 24-hour Holter. Six healthy volunteers were enrolled. Their mean driving time was 297.7 ± 111 minutes. Mean duration of sleepy time while driving was 27 ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2019.34.e56

    authors: Jo SH,Kim JM,Kim DK

    更新日期:2019-02-12 00:00:00

  • Short-term effects of 308-nm xenon-chloride excimer laser and narrow-band ultraviolet B in the treatment of vitiligo: a comparative study.

    abstract::We compared the clinical efficacy of a short-term intervention of 308-nm excimer laser with that of narrow-band UVB (NBUVB) phototherapy for vitiligo patients to see the early response. Twenty-three symmetrically patterned patches of vitiligo on 8 patients were selected. Vitiligo patches on one side of the body were t...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.2.273

    authors: Hong SB,Park HH,Lee MH

    更新日期:2005-04-01 00:00:00

  • The role of keratinocyte-derived chemokine in hemorrhage-induced acute lung injury in mice.

    abstract::Dominant inflammatory cytokines might be different depending on the underlying causes of acute lung injury (ALI). The role of kertinocyte-derived chemokine (KC), a potent chemoattractant for neutrophils, has not been clearly established in hemorrhage-induced ALI. In this study, lung injury and cytokine expression were...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2009.24.5.775

    authors: Lee BH,Lee TJ,Jung JW,Oh DJ,Choi JC,Shin JW,Park IW,Choi BW,Kim JY

    更新日期:2009-10-01 00:00:00

  • Comparison of Baseline Characteristics between Community-based and Hospital-based Suicidal Ideators and Its Implications for Tailoring Strategies for Suicide Prevention: Korean Cohort for the Model Predicting a Suicide and Suicide-related Behavior.

    abstract::In this cross-sectional study, we aimed to identify distinguishing factors between populations with suicidal ideation recruited from hospitals and communities to make an efficient allocation of limited anti-suicidal resources according to group differences. We analyzed the baseline data from 120 individuals in a commu...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2017.32.9.1522

    authors: Park CHK,Lee JW,Lee SY,Moon J,Shim SH,Paik JW,Kim SG,Cho SJ,Kim MH,Kim S,Park JH,You S,Jeon HJ,Ahn YM

    更新日期:2017-09-01 00:00:00

  • Prevalences of symptoms of asthma and other allergic diseases in korean children: a nationwide questionnaire survey.

    abstract::The purpose of this study was to estimate the national prevalence of childhood asthma and other allergic diseases in Korea, and to determine potential risk factors for the diseases. Stratified random samples of 42,886 were selected from 34 elementary (6-12 yr olds) and 34 middle schools (12-15 yr olds) nationwide, and...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2001.16.2.155

    authors: Lee SI,Shin MH,Lee HB,Lee JS,Son BK,Koh YY,Kim KE,Ahn YO

    更新日期:2001-04-01 00:00:00

  • Tissue microarray analysis of Fas and FasL expressions in human non-small cell lung carcinomas; with reference to the p53 and bcl-2 overexpressions.

    abstract::Lack of surface Fas expression is a main route for apoptotic resistance which is considered an important mechanism of tumorigenesis and tumor progression. Fas and FasL expressions in 110 non-small cell lung carcinomas (NSCLCs) were investigated to evaluate their roles in pulmonary carcinogenesis and to examine the cli...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.5.770

    authors: Myong NH

    更新日期:2005-10-01 00:00:00

  • Serologic Survey and Risk Factors for Coxiella burnetii Infection among Dairy Cattle Farmers in Korea.

    abstract:Background:The zoonotic disease Q fever is caused by Coxiella burnetii and usually affects high-risk human populations. We conducted a serological survey of dairy cattle farmers in Korea to determine seroreactivity and identify risk factors for C. burnetii infection. Methods:This cross-sectional study included 1,824 o...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e245

    authors: Park JH,Chu H,Yoo SJ,Hwang KJ,Lim HS

    更新日期:2018-08-16 00:00:00

  • Autoimmune oophoritis--a case report.

    abstract::A case is described of an autoimmune oophoritis that was diagnosed unexpectedly after a hysterectomy and bilateral salpingo-oophorectomy had been performed on the suspicion of ovarian cysts. The patient was a 43-year-old multiparous woman who presented with vaginal bleeding and lower abdominal pain which she had had f...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1992.7.3.284

    authors: Suh YL

    更新日期:1992-09-01 00:00:00

  • Fecal Calprotectin as a Useful Non-Invasive Screening Marker for Eosinophilic Gastrointestinal Disorder in Korean Children.

    abstract:BACKGROUND:Eosinophilic gastrointestinal disorder (EoGID) is an emerging disease condition in Korean children, but its diagnosis requires invasive endoscopic biopsies. Fecal calprotectin (FCal) is a noninvasive biomarker for intestinal inflammation to differentiate organic gastrointestinal diseases from functional abdo...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2020.35.e120

    authors: Yoo IH,Cho JM,Joo JY,Yang HR

    更新日期:2020-05-04 00:00:00

  • Role of healthcare in Korean long-term care insurance.

    abstract::With the rapid aging of the population, Korea introduced public long-term care insurance for older people in 2008. The long-term care insurance was designed as a separate scheme from the national health insurance, with eligibility qualifications and the certification process based on functional disability, benefits an...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2012.27.S.S41

    authors: Kang IO,Park CY,Lee Y

    更新日期:2012-05-01 00:00:00

  • Complement C3a, But Not C5a, Levels in Amniotic Fluid Are Associated with Intra-amniotic Infection and/or Inflammation and Preterm Delivery in Women with Cervical Insufficiency or an Asymptomatic Short Cervix (≤ 25 mm).

    abstract:Background:We aimed to estimate whether elevated levels of complement C3a and C5a in amniotic fluid (AF) are independently associated with increased risks of intra-amniotic infection and/or inflammation (IAI) and spontaneous preterm delivery (SPTD) in women with cervical insufficiency or a short cervix (≤ 25 mm). Meth...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e220

    authors: Kim YM,Park KH,Park H,Yoo HN,Kook SY,Jeon SJ

    更新日期:2018-07-05 00:00:00

  • Clinicopathological significance of maspin expression in breast cancer.

    abstract::Maspin is a unique serine proteinase inhibitor that has tumor suppressor activity. It has been reported that maspin is expressed in normal human mammary epithelial cells and it is down-regulated during the progression of cancer. However, to date, there is very limited data on the clinical significance of maspin expres...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2006.21.2.309

    authors: Lee MJ,Suh CH,Li ZH

    更新日期:2006-04-01 00:00:00

  • Association between Genetic Variations of MERTK and Chronic Obstructive Pulmonary Disease in Koreans.

    abstract:BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a debilitating lung disease. To date, a large number of clinical studies have been conducted to investigate the association between genetic variations and COPD. However, little is known regarding the genetic susceptibility of Koreans to this disease. MER recept...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e56

    authors: Kim WJ,Park HJ,Choi YJ,Kwon EY,Kim BM,Lee JH,Chang JH,Lee Kang J,Choi JH

    更新日期:2018-02-12 00:00:00

  • Histiocyte-rich reactive lymphoid hyperplasia of the liver: unusual morphologic features.

    abstract::Reactive lymphoid hyperplasia (RLH) of the liver is a rare entity and has also been termed nodular lymphoid lesion or pseudolymphoma of the liver. We report a case of hepatic RLH exhibiting unusual histiocyte-rich histologic features in a 47-yr-old woman in conjunction with a renal cell carcinoma. A follow-up computed...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.2008.23.1.156

    authors: Park HS,Jang KY,Kim YK,Cho BH,Moon WS

    更新日期:2008-02-01 00:00:00

  • Time to Disease Recurrence Is a Predictor of Metastasis and Mortality in Patients with High-risk Prostate Cancer Who Achieved Undetectable Prostate-specific Antigen Following Robot-assisted Radical Prostatectomy.

    abstract:Background:Robot-assisted radical prostatectomy (RARP) is a feasible treatment option for high-risk prostate cancer (PCa). While patients may achieve undetectable prostate-specific antigen (PSA) levels after RARP, the risk of disease progression is relatively high. We investigated metastasis-free survival, cancer-speci...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e285

    authors: Kim DK,Koo KC,Lee KS,Hah YS,Rha KH,Hong SJ,Chung BH

    更新日期:2018-10-16 00:00:00

  • Relationship between the Clinical Characteristics and Intervention Scores of Infants with Apparent Life-threatening Events.

    abstract::We investigated the clinical presentations, diagnostic and therapeutic modalities, and prognosis from follow-up of infants with apparent life-threatening events (ALTE). In addition, the relationship between the clinical characteristics of patients and significant intervention scores was analyzed. We enrolled patients ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2015.30.6.763

    authors: Choi HJ,Kim YH

    更新日期:2015-06-01 00:00:00

  • Clinical characteristics of idiopathic pulmonary fibrosis patients with diabetes mellitus: the national survey in Korea from 2003 to 2007.

    abstract::Evidence suggests that diabetes mellitus (DM) is associated with idiopathic pulmonary fibrosis (IPF). According to the new IPF guidelines, high-resolution computed tomography (HRCT) is an essential means of diagnosing IPF. We investigated the relationship between IPF and DM in patients treated between 2003 and 2007. N...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2012.27.7.756

    authors: Kim YJ,Park JW,Kyung SY,Lee SP,Chung MP,Kim YH,Lee JH,Kim YC,Ryu JS,Lee HL,Park CS,Uh ST,Lee YC,Kim KH,Chun YJ,Park YB,Kim DS,Jegal Y,Lee JH,Park MS,Jeong SH

    更新日期:2012-07-01 00:00:00

  • Epidemiology of HIV infection in the Republic of Korea.

    abstract::Since the first case of human immunodeficiency virus (HIV) infection in the Republic of Korea (ROK) was detected in 1985, 876 HIV-infected patients have been reported, as of December 1998. The male to female ratio was 6.8:1, and 87% of the patients were between 20 and 49 years of age. The major modes of transmission w...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1999.14.5.469

    authors: Oh MD,Choe K

    更新日期:1999-10-01 00:00:00

  • First case of Bartonella quintana endocarditis in Korea.

    abstract::Since microbial gene sequencing was utilized for etiologic diagnosis of culture-negative endocarditis, cases of Bartonella endocarditis have been reported in various countries. Herein we report the first case of Bartonella quintana endocarditis, which was confirmed for the first time in Korea by 16S rRNA gene sequenci...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2012.27.11.1433

    authors: Lim MH,Chung DR,Kim WS,Park KS,Ki CS,Lee NY,Kim SM

    更新日期:2012-11-01 00:00:00

  • Associations between oxidized LDL to LDL ratio, HDL and vascular calcification in the feet of hemodialysis patients.

    abstract::Cardiovascular mortality is associated with vascular calcification (VC) in hemodialysis (HD) patients. The present study was designed to find factors related with medial artery calcification on the plain radiography of feet by comparing C-reactive protein (CRP), plasminogen activator inhibitor type 1 (PAI-1) and lipid...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2009.24.S1.S115

    authors: An WS,Kim SE,Kim KH,Bae HR,Rha SH

    更新日期:2009-01-01 00:00:00

  • Translation and linguistic validation of the korean version of the dysfunctional voiding symptom score.

    abstract::Although studies on pediatric dysfunctional voiding are increasing, there have not been enough efforts to validate the Dysfunctional Voiding Symptom Score (DVSS) questionnaire. Therefore, we aimed to translate and validate the DVSS into Korean. The DVSS questionnaire was validated between January and October, 2013. Tw...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2014.29.3.400

    authors: Lee HE,Farhat W,Park K

    更新日期:2014-03-01 00:00:00

  • Meningococcal disease in the republic of Korea army: incidence and serogroups determined by PCR.

    abstract::This study was performed to determine the incidence and serogroups of meningococcal disease in the Korean Army. From August 2000 to July 2001, we identified prospective cases in the Korean Army. Meningococcal disease was confirmed by isolation of Neisseria meningitidis or detection of its antigen by latex agglutinatio...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.2.163

    authors: Lee SO,Ryu SH,Park SJ,Ryu J,Woo JH,Kim YS

    更新日期:2003-04-01 00:00:00

  • Asymptomatic infection by Streptococcus pyogenes in schoolchildren and diagnostic usefulness of antideoxyribonuclease B.

    abstract::This study is designed to evaluate the immune status of schoolchildren with respect to Streptococcus pyogenes, and to ascertain the usefulness of antideoxyribonuclease B (ADNase B). Antistreptolysin O (ASO) and ADNase B concentrations were measured quantitatively in 266 serum samples from healthy elementary school chi...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.6.938

    authors: Kim S,Lee NY

    更新日期:2005-12-01 00:00:00

  • Occupational reproductive function abnormalities and bladder cancer in Korea.

    abstract::The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Korean workers. In 1995, 23 of the 33 workers (25 female and 8...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.2010.25.S.S41

    authors: Park J,Shin KS,Kim Y

    更新日期:2010-12-01 00:00:00

  • A case of fetal congenital mesoblastic nephroma with oligohydramnios.

    abstract::Although congenital renal tumors are rare, congenital mesoblastic nephroma (CMN) is the most common renal tumor in early infancy. It is non-metastatic, well differentiated, amenable to surgical removal, and carries a good prognosis. Polyhydramnios has been detected in most of the published cases of CMN. However, we ex...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2007.22.2.357

    authors: Kim CH,Kim YH,Cho MK,Kim KM,Ha JA,Joo EH,Kim SM,Song TB

    更新日期:2007-04-01 00:00:00

  • Imipenem-resistant Pseudomonas aeruginosa: risk factors for nosocomial infections.

    abstract::The aim of this study was to determine the risk factors for nosocomial infections of imipenem-resistant Pseudomonas aeruginosa (IRPA). A prospective case-control study was performed at a tertiary care hospital in Ankara from January to December 2004. The patients with nosocomial P. aeruginosa infection were included i...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2008.23.6.982

    authors: Onguru P,Erbay A,Bodur H,Baran G,Akinci E,Balaban N,Cevik MA

    更新日期:2008-12-01 00:00:00

  • Comparative Research for the Healthcare Budget and Burden of Disease in Perspective Resource Allocation.

    abstract:Background:Burden of disease can be used to prioritize the healthcare budget allocation. We analyzed the research and development (R&D) budget of the Ministry of Health and Welfare (MOHW) in 2018 and compared the results with those of the 2015 Korean National Burden of Disease (KNBD) study. Methods:The 2018 MOHW R&D P...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2019.34.e81

    authors: Park SY,Yoon SJ,Park H,Jo MW,Oh IH

    更新日期:2019-03-07 00:00:00

  • Clinical significance of microvessel density in multiple myeloma patients.

    abstract::To investigate the role of angiogenesis in multiple myeloma (MM), bone marrow biopsy from 75 adults with newly diagnosed, untreated MM were evaluated. Microvessels were scored in at least 3 areas ( x 200 fields) of the highest microvessel density in representative sections of each bone marrow specimen using immunohist...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2001.16.1.45

    authors: Ahn MJ,Park CK,Choi JH,Lee WM,Lee YY,Choi IY,Kim IS,Lee WS,Ki M

    更新日期:2001-02-01 00:00:00