Translation of mRNAs for subunits of chloroplast coupling factor 1 in spinach.

abstract：:Polarization of optical fields is a crucial degree of freedom in the all-optical analogue of electromagnetically induced transparency (EIT). However, the physical origins of EIT and polarization-induced phenomena have not been well distinguished, which can lead to confusion in associated applications such as slow ligh...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wang C,Jiang X,Sweeney WR,Hsu CW,Liu Y,Zhao G,Peng B,Zhang M,Jiang L,Stone AD,Yang L

更新日期：2021-01-19 00:00:00

abstract：:The Sleeping Beauty (SB) transposon mutagenesis screen is a powerful tool to facilitate the discovery of cancer genes that drive tumorigenesis in mouse models. In this study, we sought to identify genes that functionally cooperate with sonic hedgehog signaling to initiate medulloblastoma (MB), a tumor of the cerebellu...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Genovesi LA,Ng CG,Davis MJ,Remke M,Taylor MD,Adams DJ,Rust AG,Ward JM,Ban KH,Jenkins NA,Copeland NG,Wainwright BJ

更新日期：2013-11-12 00:00:00

abstract：:The microsomal triglyceride (TG) transfer protein (MTP) is a heterodimeric lipid transfer protein that catalyzes the transport of triglyceride, cholesteryl ester, and phosphatidylcholine between membranes. Previous studies showing that the proximal cause of abetalipoproteinemia is an absence of MTP indicate that MTP f...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jamil H,Gordon DA,Eustice DC,Brooks CM,Dickson JK Jr,Chen Y,Ricci B,Chu CH,Harrity TW,Ciosek CP Jr,Biller SA,Gregg RE,Wetterau JR

更新日期：1996-10-15 00:00:00

abstract：:Evidence based on a study of alanine-resistant (Alar), constitutive mutants of CHO-K1 cells and the conditions that favor stimulation of the A system of amino acid activity supports the model that the A system of amino acid transport in these cells is repressible and under negative control of regulatory gene R1. In th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moffett J,Périer F,Jones M,Englesberg E

更新日期：1987-11-01 00:00:00

abstract：:Starving Bacillus subtilis cells execute a gene expression program resulting in the formation of stress-resistant spores. Sporulation master regulator, Spo0A, is activated by a phosphorelay and controls the expression of a multitude of genes, including the forespore-specific sigma factor σ(F) and the mother cell-speci...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Narula J,Devi SN,Fujita M,Igoshin OA

更新日期：2012-12-11 00:00:00

abstract：:Advances in direct radiocarbon dating of Neanderthal and anatomically modern human (AMH) fossils and the development of archaeostratigraphic chronologies now allow refined regional models for Neanderthal-AMH coexistence. In addition, they allow us to explore the issue of late Neanderthal survival in regions of Western...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pinhasi R,Higham TF,Golovanova LV,Doronichev VB

更新日期：2011-05-24 00:00:00

abstract：:The expression of interleukin-4 (IL-4) is viewed as the hallmark of a Th2 lymphocyte, whereas the subsequent action of IL-4 and IL-13, mediated through the STAT6 signaling pathway, is seen as a prerequisite for the full development of Th2 immune responses to parasites and allergens. G4 mice, whose IL-4 gene locus cont...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： van Panhuys N,Tang SC,Prout M,Camberis M,Scarlett D,Roberts J,Hu-Li J,Paul WE,Le Gros G

更新日期：2008-08-26 00:00:00

abstract：:We have examined the process by which small groups of pigmented germinal cells transplanted orthotopically from stage 30-38 donor embryos into stage 28-38 albino hosts contribute new postmitotic cells to the pigmented retinal epithelium of the growing larval eye in Xenopus. In the great majority of chimeric eyes, the ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hunt RK,Cohen JS,Mason BJ

更新日期：1987-05-01 00:00:00

abstract：:Two-component signal transduction systems are most often found in prokaryotic organisms where they are responsible for mediating the cellular responses to many environmental stimuli. These systems are composed of an autophosphorylating histidine kinase and a response regulator. We have found evidence for the existence...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Alex LA,Borkovich KA,Simon MI

更新日期：1996-04-16 00:00:00

abstract：:Graphene oxide (GO), the main precursor of graphene-based materials made by solution processing, is known to be very stiff. Indeed, it has a Young's modulus comparable to steel, on the order of 300 GPa. Despite its very high stiffness, we show here that GO is superflexible. We quantitatively measure the GO bending rig...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Poulin P,Jalili R,Neri W,Nallet F,Divoux T,Colin A,Aboutalebi SH,Wallace G,Zakri C

更新日期：2016-10-04 00:00:00

abstract：:Myocardial ischemic disease is the major cause of death worldwide. After myocardial infarction, reperfusion of infracted heart has been an important objective of strategies to improve outcomes. However, cardiac ischemia/reperfusion (I/R) is characterized by inflammation, arrhythmias, cardiomyocyte damage, and, at the ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Fauconnier J,Meli AC,Thireau J,Roberge S,Shan J,Sassi Y,Reiken SR,Rauzier JM,Marchand A,Chauvier D,Cassan C,Crozier C,Bideaux P,Lompré AM,Jacotot E,Marks AR,Lacampagne A

更新日期：2011-08-09 00:00:00

abstract：:The present paper summarizes future needs in information and tools, technology, infrastructure, training, funding, and bioinformatics, to provide the genomic knowledge and tools for breeding and biotechnological goals in maize. The National Corn Genome Initiative (NCGA) has developed through actions taken by the Natio...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Coe EH

更新日期：1998-03-03 00:00:00

abstract：:Previously metal-ion sites have been used as structural and functional probes in seven transmembrane receptors (7TM), but as yet all the engineered sites have been inactivating. Based on presumed agonist interaction points in transmembrane III (TM-III) and -VII of the beta(2)-adrenergic receptor, in this paper we cons...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Elling CE,Thirstrup K,Holst B,Schwartz TW

更新日期：1999-10-26 00:00:00

abstract：:Navigation, the ability to reach desired goal locations, is critical for animals and humans. Animal navigation has been studied extensively in birds, insects, and some marine vertebrates and invertebrates, yet we are still far from elucidating the underlying mechanisms in other taxonomic groups, especially mammals. He...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Tsoar A,Nathan R,Bartan Y,Vyssotski A,Dell'Omo G,Ulanovsky N

更新日期：2011-09-13 00:00:00

abstract：:Gene regulatory networks (GRNs) provide a transformation function between the static genomic sequence and the primary spatial specification processes operating development. The regulatory information encompassed in developmental GRNs thus goes far beyond the control of individual genes. We here address regulatory info...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Peter IS,Davidson EH

更新日期：2017-06-06 00:00:00

abstract：:We have used fast time-resolved infrared spectroscopy to characterize a series of organometallic methane and ethane complexes in solution at room temperature: W(CO)5(CH4) and M(eta5-C5R5)(CO)2(L) [where M = Mn or Re, R = H or CH3 (Re only); and L = CH4 or C2H6]. In all cases, the methane complexes are found to be shor...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cowan AJ,Portius P,Kawanami HK,Jina OS,Grills DC,Sun XZ,McMaster J,George MW

更新日期：2007-04-24 00:00:00

abstract：:In response to environmental stresses, the mammalian serine threonine kinases PERK, GCN2, HRI, and PKR phosphorylate the regulatory serine 51 of the eukaryotic translation initiation factor 2α (eIF2α) to inhibit global protein synthesis. Plasmodium, the protozoan that causes malaria, expresses three eIF2α kinases: IK1...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zhang M,Mishra S,Sakthivel R,Rojas M,Ranjan R,Sullivan WJ Jr,Fontoura BM,Ménard R,Dever TE,Nussenzweig V

更新日期：2012-03-06 00:00:00

abstract：:Adaptation to hypoxia is mediated by transactivation of hypoxia-responsive genes by hypoxia-inducible factor-1 (HIF-1) in complex with the CBP and p300 transcriptional coactivators. We report the solution structure of the cysteine/histidine-rich 1 (CH1) domain of p300 bound to the C-terminal transactivation domain of ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Freedman SJ,Sun ZY,Poy F,Kung AL,Livingston DM,Wagner G,Eck MJ

更新日期：2002-04-16 00:00:00

abstract：:Treatment of 45Ca2+-loaded GH3 pituitary cells with various concentrations of digitonin revealed discrete pools (I and II) of cellular 45Ca2+ defined by differing detergent sensitivities. Markers for cytosol and intracellular organelles indicated that the two 45Ca2+ pools were correlated with the two major cellular Ca...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ronning SA,Heatley GA,Martin TF

更新日期：1982-10-01 00:00:00

abstract：:We isolated mutant strains of the facultative anaerobe Salmonella typhimurium that grow either aerobically or anaerobically. Strict anaerobic mutants contained a defective DNA topoisomerase I gene (topI), while strict aerobic mutants contained a defective DNA gyrase subunit A gene (gyrA, also nalA). Topoisomerase I ac...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yamamoto N,Droffner ML

更新日期：1985-04-01 00:00:00

abstract：:Methods are described for the removal of the sporophytic pollen grain coating of Brassica oleracea and for the isolation of coat polypeptides. The coat contains a small number of proteins ranging from 6 to 45 kDa. Many of the larger proteins are glycosylated, while all carry high positive charges resulting in pI value...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Doughty J,Hedderson F,McCubbin A,Dickinson H

更新日期：1993-01-15 00:00:00

abstract：:We demonstrate the use of self-assembly for the integration of freestanding micrometer-scale components, including single-crystal, silicon field-effect transistors (FETs) and diffusion resistors, onto flexible plastic substrates. Preferential self-assembly of multiple microcomponent types onto a common platform is ach...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Stauth SA,Parviz BA

更新日期：2006-09-19 00:00:00

abstract：:Sodium influx is an important early signal during the onset of mitogenesis in many types of cells. From this observation, one would predict that a decrease in extracellular Na+ concentration might retard cell proliferation. We tested this prediction by exposing sets of cultures of monkey kidney epithelial cells (BSC-1...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Walsh-Reitz MM,Gluck SL,Waack S,Toback FG

更新日期：1986-07-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) is the principal circadian pacemaker of mammals, coordinating daily rhythms of behavior and metabolism. Circadian timekeeping in SCN neurons revolves around transcriptional/posttranslational feedback loops, in which Period (Per) and Cryptochrome (Cry) genes are negatively regulated by...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Maywood ES,Chesham JE,O'Brien JA,Hastings MH

更新日期：2011-08-23 00:00:00

abstract：:Intercropping, which grows at least two crop species on the same pieces of land at the same time, can increase grain yields greatly. Legume-grass intercrops are known to overyield because of legume nitrogen fixation. However, many agricultural soils are deficient in phosphorus. Here we show that a new mechanism of ove...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Li L,Li SM,Sun JH,Zhou LL,Bao XG,Zhang HG,Zhang FS

更新日期：2007-07-03 00:00:00

abstract：:Employing a cell-free chromatin transcription system that recapitulates progesterone receptor (PR)-mediated transcription in vivo, we have investigated further the coactivator functions of steroid receptor coactivator-1 (SRC-1) in terms of its functional domains as well as cooperation with other coactivators in PR tra...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu Z,Wong J,Tsai SY,Tsai MJ,O'Malley BW

更新日期：2001-10-23 00:00:00

abstract：:The glycine receptor (GlyR) is a pentameric ligand-gated ion channel (pLGIC) mediating inhibitory transmission in the nervous system. Its transmembrane domain (TMD) is the target of allosteric modulators such as general anesthetics and ethanol and is a major locus for hyperekplexic congenital mutations altering the al...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moraga-Cid G,Sauguet L,Huon C,Malherbe L,Girard-Blanc C,Petres S,Murail S,Taly A,Baaden M,Delarue M,Corringer PJ

更新日期：2015-03-03 00:00:00

abstract：:We posit that feasible reversal of the growth of atmospheric CH(4) and other trace gases would provide a vital contribution toward averting dangerous anthropogenic interference with global climate. Such trace gas reductions may allow stabilization of atmospheric CO(2) at an achievable level of anthropogenic CO(2) emis...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hansen J,Sato M

更新日期：2004-11-16 00:00:00

abstract：:The p6 domain of HIV-1 Gag contains highly conserved peptide motifs that recruit host machinery to sites of virus assembly, thereby promoting particle release from the infected cell. We previously reported that mutations in the YPXnL motif of p6, which binds the host protein Alix, severely impair HIV-1 replication. Pr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Van Duyne R,Kuo LS,Pham P,Fujii K,Freed EO

更新日期：2019-04-30 00:00:00

abstract：:The mechanism underlying how transcription factors regulate mesenchymal stem cell lineage commitment remains unclear. To determine the role of core-binding factor subunit beta (Cbfβ) in osteoblast lineage commitment, we generated three mouse models by deleting Cbfβ at different osteoblast lineage stages. We demonstrat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wu M,Wang Y,Shao JZ,Wang J,Chen W,Li YP

更新日期：2017-09-19 00:00:00