Effects of parathyroid hormone, 1,25-dihydroxyvitamin D3, and prostaglandin E2 on alkaline phosphatase activity in cultured dental pulp and gingiva cells of bovine calf.


:The effects of parathyroid hormone (PTH), 1,25-dihydroxyvitamin D3, and prostaglandin E2 (PGE2) on alkaline phosphatase activity on cultured dental pulp and gingiva cells of bovine calf were compared. In pulp cells, PTH, 1,25-dihydroxyvitamin D3, and PGE2 significantly increased alkaline phosphatase activity, but no increase in the enzyme activity by these factors was observed in gingiva cells. Dibutyryl cAMP also increased alkaline phosphatase activity in both types of cell, but the increase in pulp cells was greater than that in gingiva cells. Treatment of the cultured pulp cells with PTH or PGE2 significantly increased the intracellular cAMP content. These results suggest that calciotropic factors such as PTH, 1,25-dihydroxyvitamin D3, and PGE2 may be involved in the differentiation of dental pulp cells and that some of these effects (those of PTH and PGE2) are mediated by cAMP.


J Endod


Journal of endodontics


Kido J,Ishida H,Nagata T,Hamasaki A,Nishikawa S,Wakano Y





Has Abstract


1991-04-01 00:00:00














  • Heat stress activates interleukin-8 and the antioxidant system via Nrf2 pathways in human dental pulp cells.

    abstract:INTRODUCTION:This study tested whether heat stress (42 degrees C for 30 minutes) induces reactive oxygen species (ROS), proinflammatory cytokines, Nrf2 activation, and Nrf2 target genes such as antioxidant enzymes in human dental pulp (HDP) cells. METHODS:ROS was evaluated by using flow cytometry. Proteins and messeng...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Chang SW,Lee SI,Bae WJ,Min KS,Shin ES,Oh GS,Pae HO,Kim EC

    更新日期:2009-09-01 00:00:00

  • Periapical Microsurgery: A 4-dimensional Analysis of Healing Patterns.

    abstract:INTRODUCTION:Currently, the success of periapical microsurgery is determined by the restoration of the lamina dura and the elimination of symptoms. However, inadequate site preservation may prevent later implant placement. Although not possible before, the advent of cone-beam computed tomographic imaging and computer-a...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Crossen D,Morelli T,Tyndall DA,Tawil PZ

    更新日期:2019-04-01 00:00:00

  • Periapical biopsy report: an analysis of over a 10-year period.

    abstract::Biopsy reports of specimens from the apices of 1659 teeth physically present at the time the biopsy was performed were reviewed. The following information was recorded from each report: (a) source of specimen, (b) sex of patient, (c) age of patient, (d) location of tooth associated with lesion, and (e) diagnoses repor...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,评审


    authors: Spatafore CM,Griffin JA Jr,Keyes GG,Wearden S,Skidmore AE

    更新日期:1990-05-01 00:00:00

  • Improving the performance of EndoREZ root canal sealer with a dual-cured two-step self-etch adhesive. II. Apical and coronal seal.

    abstract::This study tested the hypothesis that the seal of EndoREZ may be improved with an adhesive-modified technique. Instrumented single-rooted teeth were filled with: (a) Warm vertical compaction with AH Plus (control); (b). EndoREZ with master cones and passive application of accessory cones; (c) Application of Clearfil L...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,随机对照试验


    authors: Gillespie WT,Loushine RJ,Weller RN,Mazzoni A,Doyle MD,Waller JL,Pashley DH,Tay FR

    更新日期:2006-08-01 00:00:00

  • An immunohistological study of the localization of bacteria invading root pulpal walls of teeth with periapical lesions.

    abstract::We immunohistologically examined the prevalence and localization of bacteria invading dentinal tubules of the roots of teeth with infected canals. Forty extracted teeth with apical lesions were selected and divided into two groups: a group of untreated teeth and a group of canal-enlarged teeth. The bacteria in the spe...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Matsuo T,Shirakami T,Ozaki K,Nakanishi T,Yumoto H,Ebisu S

    更新日期:2003-03-01 00:00:00

  • Treatment of a mandibular molar with perforating internal resorption.

    abstract::A case is presented in which a previous partial root canal treatment on a mandibular molar developed internal resorption of the distal canal. The case was followed at the University of Oklahoma student clinic and endodontic treatment completed in the mesial canals, with calcium hydroxide placed in the distal canal for...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Benenati FW

    更新日期:2001-07-01 00:00:00

  • The number of bleaching sessions influences pulp tissue damage in rat teeth.

    abstract:INTRODUCTION:Hydrogen peroxide tooth bleaching is claimed to cause alterations in dental tissue structures. This study investigated the influence of the number of bleaching sessions on pulp tissue in rats. METHODS:Male Wistar rats were studied in 5 groups (groups 1S-5S) of 10 each, which differed by the number (1-5) o...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Cintra LT,Benetti F,da Silva Facundo AC,Ferreira LL,Gomes-Filho JE,Ervolino E,Rahal V,Briso AL

    更新日期:2013-12-01 00:00:00

  • Effect of different grades of gum rosins and hydrogenated resins on the solubility, disintegration, and dimensional alterations of Grossman cement.

    abstract::In the present study, we investigated the effect of the addition of different grades of gum rosins and hydrogenated resins to Grossman cement on dimensional stability, solubility and disintegration. pH and conductivity, which may affect these properties, were also determined. The experiments were performed according t...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Sousa-Neto MD,Guimarães LF,Saquy PC,Pécora JD

    更新日期:1999-07-01 00:00:00

  • Pulp Innate Immune Defense: Translational Opportunities.

    abstract:INTRODUCTION:The improvement of regenerative endodontic procedures requires an understanding of the key clinical questions combined with a fundamental biological knowledge of how the dental tissues behave during health, disease, and repair. Therefore, partnerships between clinicians and basic scientists are essential t...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,评审


    authors: Duncan HF,Cooper PR

    更新日期:2020-09-01 00:00:00

  • Extracellular dextran and DNA affect the formation of Enterococcus faecalis biofilms and their susceptibility to 2% chlorhexidine.

    abstract:INTRODUCTION:Enterococcus faecalis is frequently recovered from root-filled teeth with refractory apical periodontitis. The ability of E. faecalis to form a matrix-encased biofilm contributes to its pathogenicity; however, the role of extracellular dextran and DNA in biofilm formation and its effect on the susceptibili...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Li W,Liu H,Xu Q

    更新日期:2012-07-01 00:00:00

  • Vasodilatory effect of hydroxyethyl methacrylate and triethylene glycol dimethacrylate in rat aorta through calcium antagonistic action.

    abstract:INTRODUCTION:Resin-based dental materials contain various diluent monomers that can interfere with vascular function by causing vasodilation. In this study, we evaluated the vasoactive potential of hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) and the possible mechanism of their vascul...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Guven G,Seyrek M,Vural IM,Cehreli ZC,Yildiz O

    更新日期:2011-03-01 00:00:00

  • Characteristics of accessory mental foramina observed on limited cone-beam computed tomography images.

    abstract::In this retrospective study with limited cone-beam computed tomography (limited CBCT), we investigated the anatomic characteristics of the accessory mental foramina and accessory branches of the mandibular canal. The CBCT records of approximately 150 patients were evaluated, and 17 accessory mental foramina were found...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Katakami K,Mishima A,Shiozaki K,Shimoda S,Hamada Y,Kobayashi K

    更新日期:2008-12-01 00:00:00

  • Outcome of one-visit and two-visit endodontic treatment of necrotic teeth with apical periodontitis: a randomized controlled trial with one-year evaluation.

    abstract::The choice of one-visit versus two-visit root canal therapy for necrotic teeth with apical periodontitis is a source of current debate. The primary objective of this randomized controlled clinical trial was to compare radiographic evidence of periapical healing after root canal therapy completed in one visit or two vi...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,随机对照试验


    authors: Penesis VA,Fitzgerald PI,Fayad MI,Wenckus CS,BeGole EA,Johnson BR

    更新日期:2008-03-01 00:00:00

  • Fracture strength of roots instrumented with self-adjusting file and the ProTaper rotary systems.

    abstract:INTRODUCTION:The purpose of this study was to evaluate the fracture strength of roots instrumented with the Self-Adjusting File (SAF; ReDent-Nova, Ra'anana, Israel) and the ProTaper system (Dentsply Maillefer, Ballaigues, Switzerland) and filled with the cold lateral compaction technique. METHODS:In total, 50 mandibul...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Capar ID,Altunsoy M,Arslan H,Ertas H,Aydinbelge HA

    更新日期:2014-04-01 00:00:00

  • Accuracy of Cone-beam Computed Tomography in Measuring Dentin Thickness and Its Potential of Predicting the Remaining Dentin Thickness after Removing Fractured Instruments.

    abstract:INTRODUCTION:The purpose of this study was to evaluate the accuracy of cone-beam computed tomographic (CBCT) to measure dentin thickness and its potential of predicting the remaining dentin thickness after the removal of fractured instrument fragments. METHODS:Twenty-three human mandibular molars were selected, and 4-...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Xu J,He J,Yang Q,Huang D,Zhou X,Peters OA,Gao Y

    更新日期:2017-09-01 00:00:00

  • Antibacterial Efficacy of a New Sonic Irrigation Device for Root Canal Disinfection.

    abstract:INTRODUCTION:Passive ultrasonic irrigation (PUI) is the most widespread method used to activate irrigation solutions. Concerns have been raised that PUI is less effective in curved root canals and is not passive at all. Our aim was to compare a novel passive sonic irrigation (PSI) device (6000 Hz) with PUI and manual i...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Neuhaus KW,Liebi M,Stauffacher S,Eick S,Lussi A

    更新日期:2016-12-01 00:00:00

  • Examining the Sensitivity and Specificity of 2 Screening Instruments: Odontogenic or Temporomandibular Disorder Pain?

    abstract:INTRODUCTION:Two groups of patients with orofacial pains that are clinically important to distinguish from each other are patients with odontogenic pain and temporomandibular disorder (TMD) pain. The aim of this study was to determine the sensitivity and specificity of 2 screening instruments in distinguishing between ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Fonseca Alonso B,Nixdorf DR,Shueb SS,John MT,Law AS,Durham J

    更新日期:2017-01-01 00:00:00

  • Hepatocyte growth factor exerts promoting functions on murine dental papilla cells.

    abstract::Hepatocyte growth factor (HGF) is a potent mitogenic and angiogenic factor involved in the development of many tissues including the teeth. We previously reported that dental pulp cells express the HGF receptor c-met and that HGF can enhance cell proliferation and differentiation. The purpose of this study was to dete...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Li R,Peng L,Ren L,Tan H,Ye L

    更新日期:2009-03-01 00:00:00

  • Odontogenic cutaneous sinus tract.

    abstract::Patients with odontogenic cutaneous sinus tracts usually seek treatment from a physician instead of a dentist and the etiology is frequently misdiagnosed. This case report describes a patient who sought treatment from a dentist because of a history of a previous cutaneous swelling on the ipsilateral side of his cheek....

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Foster KH,Primack PD,Kulild JC

    更新日期:1992-06-01 00:00:00

  • Mineral trioxide aggregate: a comprehensive literature review--Part I: chemical, physical, and antibacterial properties.

    abstract:INTRODUCTION:An ideal orthograde or retrograde filling material should seal the pathways of communication between the root canal system and its surrounding tissues. It should also be nontoxic, noncarcinogenic, nongenotoxic, biocompatible, insoluble in tissue fluids, and dimensionally stable. Mineral trioxide aggregate ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,评审


    authors: Parirokh M,Torabinejad M

    更新日期:2010-01-01 00:00:00

  • Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations.

    abstract::Amalgam, IRM, and a mineral trioxide aggregate were tested for repair of experimentally created root perforations. Fifty sound, extracted mandibular and maxillary molars were used in this study. A perforation was created on the mesial root surface at about a 45-degree angle to the long axis of each tooth. The tooth wa...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Lee SJ,Monsef M,Torabinejad M

    更新日期:1993-11-01 00:00:00

  • The cracked tooth: histopathologic and histobacteriologic aspects.

    abstract:INTRODUCTION:The diagnosis and treatment planning of cracked teeth depend on the understanding of how cracks affect the surrounding tissues. This study evaluated the dentin and pulp conditions in teeth affected by cracks and attrition. METHODS:Specimens under investigation included 12 cracked posterior teeth and 8 tee...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Ricucci D,Siqueira JF Jr,Loghin S,Berman LH

    更新日期:2015-03-01 00:00:00

  • A phosphate-buffered saline intracanal dressing improves the biomineralization ability of mineral trioxide aggregate apical plugs.

    abstract:INTRODUCTION:Recently, it was shown that the biomineralization process promoted by the interaction of mineral trioxide aggregate (MTA) with dentin in phosphate-buffered saline (PBS) positively influenced the push-out bond strength of the cement. This study investigated if the use of a PBS intracanal dressing promotes t...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Reyes-Carmona JF,Felippe MS,Felippe WT

    更新日期:2010-10-01 00:00:00

  • Effect of the wicking behavior of multifilament sutures.

    abstract::The purpose of this study was to compare the wicking propensity of multifilament sutures. Dexon II, Vicryl, and black silk suture (BSS) were dipped in saline or soaked for 48 h, then suspended on a microscope slide. Fluorescein isothiocyanate-dextran (FITC-D) was placed at the suture mid points, and its movement was o...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Grigg TR,Liewehr FR,Patton WR,Buxton TB,McPherson JC

    更新日期:2004-09-01 00:00:00

  • Neuropeptides in dental pulp: the silent protagonists.

    abstract::Dental pulp is a soft mesenchymal tissue densely innervated by afferent (sensory) fibers, sympathetic fibers, and parasympathetic fibers. This complexity in pulp innervation has motivated numerous investigations regarding how these 3 major neuronal systems regulate pulp physiology and pathology. Most of this research ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章,评审


    authors: Caviedes-Bucheli J,Muñoz HR,Azuero-Holguín MM,Ulate E

    更新日期:2008-07-01 00:00:00

  • Residual effects and surface alterations in disinfected gutta-percha and Resilon cones.

    abstract::The aim of this study was to evaluate alterations on the surface of gutta-percha and Resilon cones when exposed to 2% chlorhexidine gel (CHX) and 5.25% sodium hypochlorite (NaOCl) and to evaluate their possible antibacterial residual effects against Enterococcus faecalis and Porphyromonas gingivalis. A total of 270 me...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Gomes BP,Berber VB,Montagner F,Sena NT,Zaia AA,Ferraz CC,Souza-Filho FJ

    更新日期:2007-08-01 00:00:00

  • In vitro comparison of three electronic apex locators.

    abstract:INTRODUCTION:The purpose of this study was to compare the accuracy of the Root ZX II Apex Locator (RZX), the Elements Apex Locator (ELE), and the Precision Apex Locator (PAL). METHODS:Forty single-rooted extracted teeth were decoronated and the root canals coronally flared. Actual canal lengths were determined by inse...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Guise GM,Goodell GG,Imamura GM

    更新日期:2010-02-01 00:00:00

  • Cyclic Fatigue Resistance of Reciproc Blue and Reciproc Files in an S-shaped Canal.

    abstract:INTRODUCTION:This study evaluated the cyclic fatigue resistance (CFR) of Reciproc (R25 and R40; VDW, Munich, Germany) and Reciproc Blue (R25 and R40, VDW) instruments used in an artificial S-shaped canal. METHODS:A total of 80 files were tested in an S-shaped canal (n = 20 for each file, Reciproc R25 and R40 and Recip...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Topçuoğlu HS,Topçuoğlu G

    更新日期:2017-10-01 00:00:00

  • Large-scale clinical endodontic research in the National Dental Practice-Based Research Network: study overview and methods.

    abstract:INTRODUCTION:This article reports on the feasibility of conducting a large-scale endodontic prospective cohort study in The National Dental Practice-Based Research Network. This study was designed to measure pain and burden associated with initial orthograde root canal therapy (RCT) and to explore potential prognostic ...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Nixdorf DR,Law AS,Look JO,Rindal DB,Durand EU,Kang W,Agee BS,Fellows JL,Gordan VV,Gilbert GH,National Dental PBRN Collaborative Group.

    更新日期:2012-11-01 00:00:00

  • Cracked tooth syndrome: characteristics and distribution among adults in a Nigerian teaching hospital.

    abstract::This study highlighted the characteristics and distribution of cracked tooth syndrome (CTS) and the associated factors in adult attendees in the University of Nigeria Teaching Hospital. Three hundred seventy patients aged 18 years to 77 years with CTS-like conditions were included and studied over 12 months. The follo...

    journal_title:Journal of endodontics

    pub_type: 杂志文章


    authors: Udoye CI,Jafarzadeh H

    更新日期:2009-03-01 00:00:00