Patients, their doctors, nonsteroidal anti-inflammatory drugs and the perception of risk.

Abstract:

:This article is about risk. Risk is probably the most misunderstood component in determining therapeutic intervention; however, it is probably the most relevant issue to consider in the context of expected benefit. The rarity of quantitative risk-benefit assessment and the lack of comparative risk-benefit when alternative therapies exist for a given condition leads to inadequate decisions. Without some quantitation of the risks associated with specific therapies, doctors and patients cannot make optimal risk-benefit calculations. Patients may abandon effective therapies for which benefits may still outweigh risks, or opt for therapies with less well-publicized potential adverse events of even greater frequency or severity. When only small incremental benefits accrue to patients from the use of a given therapy, on the other hand, even very rare serious events may play a role in decision-making by patients, by their health care providers and by regulatory authorities.

journal_name

Arthritis Res Ther

authors

Goldkind L,Simon LS

doi

10.1186/ar1924

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

105

issue

2

eissn

1478-6354

issn

1478-6362

pii

ar1924

journal_volume

8

pub_type

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