Abstract:
:Several 2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1H-benzimidazole-5-carboxamidine analogues were synthesized for their antibacterial and antifungal activities against S. aureus, Methicillin-resistant S. aureus (MRSA), C. albicans, and C. krusei. MIC values of the targeted compounds 43-58 are comparable to those of Fluconazole and Sultamicillin. The most potent compounds, 51 and 53, showed MIC values as 0.78 and 1.56 microg/mL against S. aureus and C. albicans, respectively.
journal_name
Arch Pharm (Weinheim)journal_title
Archiv der Pharmazieauthors
Ates-Alagöz Z,Alp M,Kus C,Yildiz S,Buyukbingöl E,Göker Hdoi
10.1002/ardp.200500168keywords:
subject
Has Abstractpub_date
2006-02-01 00:00:00pages
74-80issue
2eissn
0365-6233issn
1521-4184journal_volume
339pub_type
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