Abstract:
STUDY OBJECTIVE:The aim was to assess the interrelationship between alcohol intake, cigarette smoking, body weight, and blood lipid concentrations. DESIGN:This was the cross sectional (screening) phase of a prospective study. The main outcome measure was the blood lipids (serum total cholesterol, HDL cholesterol, and triglycerides). SETTING:General practices in 24 towns (The British Regional Heart Study). SUBJECTS:Subjects were 7735 men aged 40-59 years, selected at random from the age-sex registers of one group practice in each of the 24 towns. RESULTS:Univariate analysis showed little association between alcohol intake and total cholesterol, a strong positive relation with HDL cholesterol, and a significant increase in triglycerides in heavy drinkers. A strong positive association between alcohol intake and body weight was present in non-smokers but not in moderate/heavy smokers. With the exception of HDL cholesterol, the relationships between alcohol intake and serum lipids were significantly different in smokers and non-smokers, apparently due to the opposing effect of smoking on blood lipids and body weight. Total cholesterol and triglycerides were significantly and positively associated with alcohol intake in non-smokers, the cholesterol association being largely mediated by the influence of alcohol on body weight. In smokers, no such association was seen: current smokers who were heavy drinkers or non-drinkers had the lowest mean cholesterol levels. CONCLUSIONS:The association between alcohol intake and body weight and alcohol intake and blood lipids are strongly conditioned by cigarette smoking. Simple standardisation for smoking in multivariate analyses may obscure the independent relationship with alcohol. These findings are of importance in studies seeking to relate alcohol intake, body weight, or cigarette smoking to blood lipid concentrations, or blood lipid concentration to morbidity or mortality.
journal_name
J Epidemiol Community Healthjournal_title
Journal of epidemiology and community healthauthors
Wannamethee G,Shaper AGdoi
10.1136/jech.46.3.197keywords:
subject
Has Abstractpub_date
1992-06-01 00:00:00pages
197-202issue
3eissn
0143-005Xissn
1470-2738journal_volume
46pub_type
杂志文章abstract:STUDY OBJECTIVE:To investigate the association of sexual problems with social, physical, and psychological problems. DESIGN:An anonymous postal questionnaire survey. SETTING:Four general practices in England. PARTICIPANTS:789 men and 979 women responding to a questionnaire sent to a stratified random sample of the a...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.53.3.144
更新日期:1999-03-01 00:00:00
abstract::Birthweight and gestational age are the two most commonly used continuous variables in perinatal research. Dichotomous outcomes derived from these two variables include low birthweight, preterm birth and small for gestational age, each extensively used as perinatal and population health indicators within public health...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2011-200772
更新日期:2012-11-01 00:00:00
abstract:STUDY OBJECTIVE:Several studies on differences in infant outcome by socioeconomic position have been done, but these have usually been based on ad hoc data linkages. The aim of this paper was to investigate whether socioeconomic differences in perinatal health in Finland could be regularly monitored using routinely col...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.57.6.433
更新日期:2003-06-01 00:00:00
abstract::More than 30 years ago, the older of us published a paper with the proposal that all scientific papers should start with a statement along the lines of: "These are the opinions on which I base my facts". Why pretend? To take a topical example, if you are on the nature side of the nature/nurture debates, is it likely t...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.081695
更新日期:2008-12-01 00:00:00
abstract::The perinatal mortality rates of mothers who delivered at St. Thomas's Hospital from 1969 to 1976 have been examined. The rate in the West Indian population was significant higher than in the United Kingdom white population. The increased West Indian mortality was confined to infants with a birth weight of more than 2...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.36.1.22
更新日期:1982-03-01 00:00:00
abstract:BACKGROUND:The effect of mild-to-moderate maternal iodine deficiency on the neuropsychological development of their offspring is uncertain. We aimed to assess the association between iodine status during pregnancy and the cognitive and motor development of children at 4-5 years. METHODS:We conducted a prospective coho...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2017-209830
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:The fall in the prevalence of left handedness with age has been attributed to either premature mortality or a cohort effect of forced dextrality. Evidence for forced dextrality was sought to differentiate between these competing theories. DESIGN:6097 Edinburgh handedness inventories were used to calculate l...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.52.1.41
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2015-205542
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Blood pressure is positively associated with ischaemic heart disease (IHD) mortality, but the strength of the association declines with age, and may differ between lean and obese people. OBJECTIVE:To study the association of blood pressure with IHD mortality stratified by attained age (<65 and ≥65 years) an...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2009.094110
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:While many epidemiological studies have shown that low outdoor temperatures are associated with increased rates of hospitalisation and mortality (especially for respiratory or cardiovascular disease), very few studies have looked at the association between indoor temperatures and health. Such studies are c...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,随机对照试验
doi:10.1136/jech-2013-202632
更新日期:2013-11-01 00:00:00
abstract::A recent review of the literature identified several common methodological weaknesses in studies of the effects of occupational exposures on male and female reproductive processes. This paper suggests a strategy which addresses these problems, by the use of a standard method. The potential benefits include increased m...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.42.3.209
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:Resource allocation and integration of services have been of interest recently to achieve health-related Millennium Development Goals. This paper analyses the extent to which countries receiving funding in HIV were able to invest in activities in the area of sexual and reproductive health (SRH). METHODS:The...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2009.092940
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Limited research has shown a possible association between exposure to physical or sexual abuse prior to age 18 and the risk of developing hypertension as an adult. The factors mediating this relationship are unknown. METHODS:Questionnaire data from 68 505 female participants in the Nurses' Health Study II w...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2009.095109
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:We investigated the influence of sleeplessness and number of insomnia symptoms on the probability of recovery from chronic low back pain (LBP), and the possible interplay between sleeplessness and co-occurring musculoskeletal pain on this association. METHODS:The study comprised data on 3712 women and 2488 ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2019-212734
更新日期:2020-03-01 00:00:00
abstract::Socioeconomic differentials in the uptake of medical care in men were investigated using data from the General Household Survey (1974-76 and 1979-80). Hospitalisation, attendance at out patient clinics, and consultation with doctors were higher in local authority tenants than in owner occupiers. Men belonging to the m...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.41.3.196
更新日期:1987-09-01 00:00:00
abstract:STUDY OBJECTIVE:To explore individual and social factors that could predict health care utilisation and medication among people with chronic pain in an unselected population. DESIGN:A mailed survey with questions about pain and mental symptoms, disability, self care action, visits to health care providers, and medicat...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.53.8.503
更新日期:1999-08-01 00:00:00
abstract:STUDY OBJECTIVE:To explore risk factors for symptomatic knee osteoarthritis (OAK) in women, which included wearing high heeled shoes. DESIGN:Matched case-control study. Exposure information obtained by interview, included details about past footwear. Self reported weight and height data obtained representing when wome...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.57.10.823
更新日期:2003-10-01 00:00:00
abstract::Records in the obstetric wards and nurseries of 18 hospitals were reviewed and studied epidemiologically, covering about 210,000 deliveries and 1000 cases of neural tube defects (NTD). All live and still births occurred in the period 1970-84. Following the NTD classification used by Koch (1984), our case series consis...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.41.3.259
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:The most direct way in which climate change is expected to affect public health relates to changes in mortality rates associated with exposure to ambient temperature. Many countries worldwide experience annual heat-related and cold-related deaths associated with current weather patterns. Future changes in cl...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2013-202449
更新日期:2014-07-01 00:00:00
abstract::Since the early 1960s notification rates for tuberculosis in England and Wales for the whole population have been influenced by high rates in certain ethnic groups. Using data based on country of birth from the British (Thoracic and) Tuberculosis Association surveys of 1965 and 1971, and based on ethnic origin from th...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.42.4.370
更新日期:1988-12-01 00:00:00
abstract:OBJECTIVE:To examine variables related with publication bias assessment in a sample of systematic reviews with meta-analysis on cardiovascular diseases. DESIGN:Systematic review of meta-analyses. SETTING:Journals indexed in Medline and the Cochrane Library. STUDY POPULATION:225 reviews with meta-analysis published b...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech.2005.033027
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Urban green spaces have been linked to different health benefits, but longitudinal studies on the effect of green spaces on mental health are sparse and evidence often inconclusive. Our objective was to study the effect of changes in green spaces in the residential environment on changes in mental health usi...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2019-212704
更新日期:2020-01-01 00:00:00
abstract::Five-year age-specific incidence rates were shown to produce small but systematic errors in the calculation of the expected number of tumours in a hypothetical but realistic study population. Underestimates occurred at younger ages (under 55) and overestimates at older ages, with a small overestimate (0.22%) overall. ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.35.2.146
更新日期:1981-06-01 00:00:00
abstract:STUDY OBJECTIVE:The aim was to investigate whether the survival of women with cancer of the uterine cervix is associated with their marital status and social class. DESIGN:The study was a survey of survival up to 5 years from diagnosis of women with cancer of the cervix registered in the South Thames Cancer Registry, ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.44.4.293
更新日期:1990-12-01 00:00:00
abstract:STUDY OBJECTIVE:The main cause of breast cancer remains unknown. Numerous causal factors or predisposing conditions have been proposed, but account for only a small percentage of the total disease. The current search for multiple causes is unavailing. This report explores whether any single aetiological agent may be re...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech.54.11.851
更新日期:2000-11-01 00:00:00
abstract::In industrialised countries, mortality and morbidity are dominated by age related chronic degenerative diseases. The health and health care needs of future populations will be heavily determined by these conditions of old age. Two opposite scenarios of future morbidity exist: morbidity might decrease ("compress"), bec...
journal_title:Journal of epidemiology and community health
pub_type: 历史文章,杂志文章
doi:10.1136/jech.52.10.619
更新日期:1998-10-01 00:00:00
abstract::A study of 150 hotel prostitutes in Lagos was undertaken to determine their socioeconomic identity and, through an assessment of their health knowledge, attitude, and practice, their probable impact on public health. The subjects were selected from 15 hotels, representing 20% of the estimated hotel universe in Lagos a...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.34.4.312
更新日期:1980-12-01 00:00:00
abstract:BACKGROUND:Efforts to end preventable newborn deaths will fail if the poor are not reached with effective interventions. To understand what works to reach vulnerable groups, we describe and explain the uptake of a highly effective community-based newborn health intervention across social strata in Asia and Africa. MET...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-204685
更新日期:2016-01-01 00:00:00
abstract:STUDY OBJECTIVE:To assess the potential for substituting alternative forms of care for admission to an acute hospital in particular groups of patients. DESIGN:A screening tool, the intensity-severity-discharge review system with adult criteria (ISD-A), developed for hospital utilisation review in the USA, was used in ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.49.2.194
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:Although working smoke alarms halve deaths in residential fires, many households do not keep alarms operational. We tested whether theory-based education increases alarm operability. METHODS:Randomised multiarm trial, with a single arm randomly selected for use each day, in low-income neighbourhoods in Mary...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,随机对照试验
doi:10.1136/jech-2014-204182
更新日期:2014-12-01 00:00:00