Effect of gemfibrozil on composition of lipoproteins and distribution of LDL subspecies.

abstract：INTRODUCTION:The apolipoproteinB (apoB)/apolipoproteinA-I (apoA-I) ratio mirrors the number of pro-atherogenic and anti-atherogenic lipoprotein particles. This ratio may carry more information on risk for atherosclerosis than LDL in cohorts with impaired glucose tolerance. The aim was to examine the association between...

journal_title：Atherosclerosis

authors： Schmidt C,Fagerberg B

更新日期：2008-02-01 00:00:00

abstract：:Five homozygous patients with familial hypercholesterolemia (FH) are described. Their serum cholesterol levels were between 603 and 907 mg/dl, with an average of 714 mg/dl. The mean value of serum cholesterol levels of the obligate heterozygous parents was 270 mg/dl. In the patient group, 87% of the serum cholesterol ...

journal_title：Atherosclerosis

authors： Cai HJ,Fan LM,Huang MG,Chen XY,Liu GQ,Chen Q

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Galectin-3 binding protein (Gal-3BP) is a secreted protein associated with inflammation and carotid atherosclerosis. We hypothesized that high Gal-3BP levels may indicate unfavorable plaque morphology and outcome in coronary artery disease (CAD). METHODS:Gal-3BP plasma levels were measured by ELISA...

journal_title：Atherosclerosis

authors： Gleissner CA,Erbel C,Linden F,Domschke G,Akhavanpoor M,Doesch AO,Buss SJ,Giannitsis E,Katus HA,Korosoglou G

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has not been fully determined whether non-high-density lipoprotein cholesterol (non-HDLC) levels are involved in vascular events, especially stroke, in general Asian populations. We evaluated the association between non-HDLC levels and the risk of type-specific cardiovascular disease in a pros...

journal_title：Atherosclerosis

authors： Imamura T,Doi Y,Ninomiya T,Hata J,Nagata M,Ikeda F,Mukai N,Hirakawa Y,Yoshida D,Fukuhara M,Kitazono T,Kiyohara Y

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:To examine the longitudinal association between toenail selenium levels and subclinical atherosclerosis over an 18-year period. METHODS:Toenail selenium concentrations were examined among 3112 Americans age 20-32 years in 1987 and measured by instrumental neutron-activation analysis. Subclinical atheroscler...

journal_title：Atherosclerosis

authors： Xun P,Liu K,Morris JS,Daviglus ML,He K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolemia (FH) is the most common and severe autosomal dominant lipid metabolism dysfunction, which causes xanthoma, atherosclerosis and coronary heart disease. Earlier studies showed that mutations in LDLR, APOB and PCSK9 cause FH. Although more than 75% of the population in Eur...

journal_title：Atherosclerosis

authors： Xiang R,Fan LL,Lin MJ,Li JJ,Shi XY,Jin JY,Liu YX,Chen YQ,Xia K,Zhao SP

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The pathogenesis of abdominal aortic aneurysm (AAA) shares several common pathways with atherosclerosis. Prospective clinical plasma biomarker studies in AAA have been hampered by the need for very large cohorts and long follow-up time. METHODS:We analyzed a prospective longitudinal cohort of middl...

journal_title：Atherosclerosis

authors： Acosta S,Taimour S,Gottsäter A,Persson M,Engström G,Melander O,Zarrouk M,Nilsson PM,Smith JG

更新日期：2017-07-01 00:00:00

abstract：:This report concerns a heart transplant patient with hypercholesterolemia who showed rapid development of a severe transplant coronary artery disease. The patient received 10 mg pravastatine per day. Quantitative coronary angiography analyses of 4 serial angiograms clearly demonstrated that in the first 2.5 years foll...

journal_title：Atherosclerosis

authors： Park JW,Vermeltfoort M,Braun P,May E,Merz M

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Generally, immoderate alcohol consumption is associated with variant angina and accepted as one of the risk factors for coronary artery spasm (CAS), but evidence is lacking in this regard. The aim of this study is to evaluate the impact of alcohol consumption and drinking pattern on CAS by acetylcho...

journal_title：Atherosclerosis

authors： Sohn SM,Choi BG,Choi SY,Byun JK,Mashaly A,Park Y,Jang WY,Kim W,Choi JY,Park EJ,Na JO,Choi CU,Lim HE,Kim EJ,Park CG,Seo HS,Oh DJ,Rha SW

更新日期：2018-01-01 00:00:00

abstract：:Recent studies demonstrate important roles for inflammation in development of atherosclerosis with current attention focusing on interactions of inflammation with traditional lipoprotein risk factors. Since the nature of such relationships is largely unknown, we sought to investigate interactions of inflammation with ...

journal_title：Atherosclerosis

authors： Corsetti JP,Zareba W,Moss AJ,Rainwater DL,Sparks CE

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Increasing age and cholesterol levels, male gender, and family history of early coronary heart disease (CHD) are associated with early onset of CHD in familial hypercholesterolemia (FH). OBJECTIVE:Assess subclinical atherosclerosis by computed tomography coronary angiography (CTCA) and its association with ...

journal_title：Atherosclerosis

authors： Miname MH,Ribeiro MS 2nd,Parga Filho J,Avila LF,Bortolotto LA,Martinez LR,Rochitte CE,Santos RD

更新日期：2010-12-01 00:00:00

abstract：:The effectiveness of a new, almost l-thyroxine free preparation of d-thyroxine (Dynothel) was tested in 15 patients with Type IIa and 4 patients with Type IIb hyperlipoproteinemia. Eleven patients with Type IIa and 3 with Type IIb were responsive to treatment and showed an average 26% decrease in plasma TC. This decre...

journal_title：Atherosclerosis

authors： Rakow AD,Klor HU,Kuter E,Ditschuneit HH,Ditschuneit H

更新日期：1976-09-01 00:00:00

abstract：:Factor XIII is a transglutaminase that crosslinks fibrin in the last steps of the coagulation process. A few polymorphic sites have been identified in this gene, one of them being a point mutation (FXIII Val34Leu), leading to an amino acid change of valine to leucine. Recently, in British patients, FXIII 34Leu allele ...

journal_title：Atherosclerosis

authors： Wartiovaara U,Perola M,Mikkola H,Tötterman K,Savolainen V,Penttilä A,Grant PJ,Tikkanen MJ,Vartiainen E,Karhunen PJ,Peltonen L,Palotie A

更新日期：1999-02-01 00:00:00

abstract：:Atherosclerosis is an inflammatory disease characterised by increased expression of adhesion molecules for leukocytes on both the surface of dysfunctional endothelium and on smooth muscle cells (SMC) within the lesion. It is also characterised by altered SMC phenotypic expression, indicated by a decreased volume fract...

journal_title：Atherosclerosis

authors： Rolfe BE,Muddiman JD,Smith NJ,Campbell GR,Campbell JH

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:To evaluate whether higher circulating levels of complement proteins C3 and C4 are associated with menopausal status and with hemostatic/thrombus formation markers (circulating factor VII (factor VIIc), fibrinogen, plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator antigen (tPA-ag)) in...

journal_title：Atherosclerosis

authors： El Khoudary SR,Shields KJ,Chen HY,Matthews KA

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Atherosclerotic plaques are heterogeneous with respect to inflammation, calcification, vascularity, oxygen, and temperature. We hypothesized that they also vary in pH and measured pH in living human carotid endarterectomized atherosclerotic plaques (CEA), Watanabe heritable hyperlipidemic (WHHL) rabbit aorta...

journal_title：Atherosclerosis

authors： Naghavi M,John R,Naguib S,Siadaty MS,Grasu R,Kurian KC,van Winkle WB,Soller B,Litovsky S,Madjid M,Willerson JT,Casscells W

更新日期：2002-09-01 00:00:00

abstract：:Endothelial cells (EC) were harvested by 0.1% collagenase treatment for adult human thoracic aortas obtained 1-3 h after sudden death. At least 35-70% of EC were removed from the intimal surface of aorta, 90-95% of them being viable. Plating efficiency was 70-80%. Monolayer formation was achieved at a seeding density ...

journal_title：Atherosclerosis

authors： Antonov AS,Nikolaeva MA,Klueva TS,Romanov YuA,Babaev VR,Bystrevskaya VB,Perov NA,Repin VS,Smirnov VN

更新日期：1986-01-01 00:00:00

abstract：:Seasonal variation in the plasma lipids and lipoproteins is reported in the literature. Whether this variation is the result of changes in diet or other factors has not been adequately addressed. We investigated the effects of a controlled diet on the seasonal variation in the levels of plasma lipids and apolipoprotei...

journal_title：Atherosclerosis

authors： Mustad V,Derr J,Reddy CC,Pearson TA,Kris-Etherton PM

更新日期：1996-09-27 00:00:00

abstract：:Topographic distribution of atherosclerotic lesions of the aortic valve was investigated in rabbits on a 2%-cholesterol-enriched diet and related to distribution of intramural stress in the valve. Initially the lesions appeared at the base of the leaflet on the aortic face and with time spread further out into the lea...

journal_title：Atherosclerosis

authors： Thubrikar MJ,Deck JD,Aouad J,Chen JM

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:Limited evidence suggests NT-proBNP improves prediction of coronary heart disease (CHD) events but further data are needed, especially in people without pre-existing CHD and in women. METHODS:We measured NT-proBNP in serum from 162 women with incident CHD events and 1226 controls (60-79 years) in a case-cont...

journal_title：Atherosclerosis

authors： Sattar N,Welsh P,Sarwar N,Danesh J,Di Angelantonio E,Gudnason V,Davey Smith G,Ebrahim S,Lawlor DA

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysfunctional high-density lipoprotein (HDL) is a risk factor for cardiovascular disease (CVD) beyond HDL concentrations. Recently, a novel method has been introduced to measure LOX-1 ligand containing apolipoprotein AI (LAA), which is an indicator of various types of modified HDL with binding capac...

journal_title：Atherosclerosis

authors： Hirata A,Kakino A,Okamura T,Usami Y,Fujita Y,Kadota A,Fujiyoshi A,Hisamatsu T,Kondo K,Segawa H,Sawamura T,Miura K,Ueshima H,SESSA Research Group.

更新日期：2020-11-01 00:00:00

abstract：:We studied the kinetic parameters of high density lipoprotein (HDL) cholesteryl esters in the cebus monkey, an animal species with high plasma cholesteryl ester transfer activity. HDL were radiolabeled with cholesteryl [1-14C]oleate and intravenously administered to 4 cebus monkeys. The calculated fractional catabolic...

journal_title：Atherosclerosis

authors： Terpstra AH,Stucchi AF,Nicolosi RJ

更新日期：1991-06-01 00:00:00

abstract：:The evaluation of the health effects of low-dose ionizing radiation has always been a focus of debate and investigation within the scientific community. During the last decade, epidemiological studies provided evidence that an excess risk of cardiovascular diseases (CVDs) can be associated with moderate and low dose r...

journal_title：Atherosclerosis

authors： Borghini A,Gianicolo EA,Picano E,Andreassi MG

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Increased lipid accumulation in cells and tissues is a key phenomenon in the development of obesity, insulin resistance, and atherosclerosis. In the regulation of lipid content of cells and tissues the SREBPs play a dominant role as transcription factors. METHODS:Since growth hormone (GH) affects lipid metab...

journal_title：Atherosclerosis

authors： Kotzka J,Knebel B,Avci H,Jacob S,Nitzgen U,Jockenhovel F,Heeren J,Haas J,Muller-Wieland D

更新日期：2010-11-01 00:00:00

abstract：:Fatty acids have been implicated in having both anti- or pro-inflammatory actions, which may contribute to the progression and severity of atherosclerosis. Linoleic acid has been shown by others to decrease CD18 expression and leukocyte adhesion under static conditions. We investigated the effect of steric acid (18:0)...

journal_title：Atherosclerosis

authors： Rinker KD,Kirkpatrick AP,Ting-Beall HP,Shepherd RD,Levin JD,Irick J,Thomas JL,Truskey GA

更新日期：2004-12-01 00:00:00

abstract：:Contrasting observations have been made between serum urate and ischemic stroke outcomes in studies involving Caucasian populations. To assess the hypothesis that urate is associated with stroke outcomes, a prospective follow-up study was performed in a cohort of Asian patients with ischemic stroke. Patients diagnosed...

journal_title：Atherosclerosis

authors： Seet RC,Kasiman K,Gruber J,Tang SY,Wong MC,Chang HM,Chan YH,Halliwell B,Chen CP

更新日期：2010-03-01 00:00:00

abstract：:Polar coordinate mapping was used to determine the rate of growth of individual sudanophilic lesions on the aortic wall around several major branches of the aortae of cholesterol fed rabbits. Four groups, with 6 8-month old male albino white rabbits in each, were used in the study. One group served as a control and th...

journal_title：Atherosclerosis

authors： Roach MR,Fletcher J,Cornhill JF

更新日期：1976-10-01 00:00:00

abstract：OBJECTIVE:Subjects with metabolic syndrome (MetS) and individuals with type 2 diabetes are at high risk for vascular complications. Hormones acting on vascular endothelium may be involved in the atherogenic process associated with metabolic disorders. The objective of this study was to determine the correlation of pro-...

journal_title：Atherosclerosis

authors： Then C,Kowall B,Lechner A,Meisinger C,Heier M,Koenig W,Peters A,Thiery J,Rathmann W,Seissler J

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To assess the effect on oxidative damage of the administration of a Mediterranean diet (MD) compared with an Occidental diet (OD), in young adult volunteers, with or without the concomitant intake of red wine. DESIGN:Forty-two omnivorous male students 20-27 years old were given either diet for 3 months. Duri...

journal_title：Atherosclerosis

authors： Urquiaga I,Strobel P,Perez D,Martinez C,Cuevas A,Castillo O,Marshall G,Rozowski J,Leighton F

更新日期：2010-08-01 00:00:00

abstract：:Trained people exhibit low plasma concentrations of triacylglcyeride (TAG) in both fasted and postprandial states. This mainly reflects enhanced uptake of TAG into skeletal muscle, via enhanced activity of lipoprotein lipase, the rate-limiting step in TAG removal. Endurance athletes possess a large, well-vascularised ...

journal_title：Atherosclerosis

authors： Hardman AE

更新日期：1998-12-01 00:00:00