Abstract:
:Natural oligopeptides may regulate nearly all vital processes. To date, the chemical structures of nearly 6000 oligopeptides have been identified from >1000 organisms representing all the biological kingdoms. We have compiled the known physical, chemical and biological properties of these oligopeptides--whether synthesized on ribosomes or by non-ribosomal enzymes--and have constructed an internet-accessible database, EROP-Moscow (Endogenous Regulatory OligoPeptides), which resides at http://erop.inbi.ras.ru. This database enables users to perform rapid searches via many key features of the oligopeptides, and to carry out statistical analysis of all the available information. The database lists only those oligopeptides whose chemical structures have been completely determined (directly or by translation from nucleotide sequences). It provides extensive links with the Swiss-Prot-TrEMBL peptide-protein database, as well as with the PubMed biomedical bibliographic database. EROP-Moscow also contains data on many oligopeptides that are absent from other convenient databases, and is designed for extended use in classifying new natural oligopeptides and for production of novel peptide pharmaceuticals.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Zamyatnin AA,Borchikov AS,Vladimirov MG,Voronina OLdoi
10.1093/nar/gkj008keywords:
subject
Has Abstractpub_date
2006-01-01 00:00:00pages
D261-6issue
Database issueeissn
0305-1048issn
1362-4962pii
34/suppl_1/D261journal_volume
34pub_type
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