The EROP-Moscow oligopeptide database.

Abstract:

:Natural oligopeptides may regulate nearly all vital processes. To date, the chemical structures of nearly 6000 oligopeptides have been identified from >1000 organisms representing all the biological kingdoms. We have compiled the known physical, chemical and biological properties of these oligopeptides--whether synthesized on ribosomes or by non-ribosomal enzymes--and have constructed an internet-accessible database, EROP-Moscow (Endogenous Regulatory OligoPeptides), which resides at http://erop.inbi.ras.ru. This database enables users to perform rapid searches via many key features of the oligopeptides, and to carry out statistical analysis of all the available information. The database lists only those oligopeptides whose chemical structures have been completely determined (directly or by translation from nucleotide sequences). It provides extensive links with the Swiss-Prot-TrEMBL peptide-protein database, as well as with the PubMed biomedical bibliographic database. EROP-Moscow also contains data on many oligopeptides that are absent from other convenient databases, and is designed for extended use in classifying new natural oligopeptides and for production of novel peptide pharmaceuticals.

journal_name

Nucleic Acids Res

journal_title

Nucleic acids research

authors

Zamyatnin AA,Borchikov AS,Vladimirov MG,Voronina OL

doi

10.1093/nar/gkj008

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

D261-6

issue

Database issue

eissn

0305-1048

issn

1362-4962

pii

34/suppl_1/D261

journal_volume

34

pub_type

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