Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disorders.

Abstract:

:Children and adolescents with bipolar disorder (BD) have a high incidence of comorbid attention-deficit/hyperactivity disorder (ADHD). In this paper, we report a consecutive case series on 7 patients with pediatric BD and ADHD who were treated with atomoxetine-and all but one were also treated in conjunction with mood stabilizers. All patients were outpatients at the Stanford Pediatric Bipolar Disorders Clinic. Information on patients was collected in a retrospective chart review. All but 1 patient demonstrated significant improvement in symptoms of ADHD. No patients had episodes of hypomania or mania during the treatment period. Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. These cases suggest that atomoxetine may be a safe and effective treatment for ADHD in conjunction with mood stabilizers in children with BD.

authors

Hah M,Chang K

doi

10.1089/cap.2005.15.996

keywords:

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

996-1004

issue

6

eissn

1044-5463

issn

1557-8992

journal_volume

15

pub_type

杂志文章
  • Does pharmacotherapy for attention-deficit/hyperactivity disorder predict risk of later major depression?

    abstract:OBJECTIVE:This study's goal was to determine among youths with attention-deficit/hyperactivity disorder (ADHD) how the history of ADHD pharmacotherapy influenced the risk of developing major depressive disorder (MDD), compared to other commonly reported predictors. METHOD:Diagnostic and treatment history data were ana...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2007.0100

    authors: Daviss WB,Birmaher B,Diler RS,Mintz J

    更新日期:2008-06-01 00:00:00

  • Risperidone treatment of children with autistic disorder: effectiveness, tolerability, and pharmacokinetic implications.

    abstract:BACKGROUND:Recent evidence indicates that atypical antipsychotics represent a promising option for the treatment of autistic disorder. In particular, risperidone appears to be effective in treating aggressiveness, hyperactivity, irritability, stereotypies, social withdrawal, and lack of interests. OBJECTIVE:The aim of...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1089/104454604773840472

    authors: Gagliano A,Germanò E,Pustorino G,Impallomeni C,D'Arrigo C,Calamoneri F,Spina E

    更新日期:2004-04-01 00:00:00

  • Atomoxetine treatment in adolescents with attention-deficit/hyperactivity disorder.

    abstract:INTRODUCTION:This study compared two atomoxetine titration dosing schedules and two atomoxetine maintenance doses for treating adolescent attention-deficit/hyperactivity disorder (ADHD) inattention and hyperactivity/impulsivity. METHODS:Adolescents (N = 267) were randomized to a slow or fast titration schedule. Patien...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章,随机对照试验

    doi:10.1089/cap.2008.074

    authors: Wietecha LA,Williams DW,Herbert M,Melmed RD,Greenbaum M,Schuh K

    更新日期:2009-12-01 00:00:00

  • Duloxetine treatment of pediatric chronic pain and co-morbid major depressive disorder.

    abstract::In the United States, the novel compound duloxetine has been approved for the treatment of major depressive disorder (MDD) and diabetic peripheral neuropathic pain in the adult population. There are currently no published data on the use of duloxetine in children and adolescents. This report describes the successful t...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2006.0042

    authors: Meighen KG

    更新日期:2007-02-01 00:00:00

  • Pemoline treatment of adolescents with attention deficit hyperactivity disorder: a short-term controlled trial.

    abstract:BACKGROUND:Despite the increased recognition of attention deficit hyperactivity disorder (ADHD) in adolescents, few controlled studies have assessed treatments for this age group. Adolescent issues, such as embarrassment at receiving medication at school and experimentation with abusable substances, have accelerated ef...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1089/10445460050167313

    authors: Bostic JQ,Biederman J,Spencer TJ,Wilens TE,Prince JB,Monuteaux MC,Sienna M,Polisner DA,Hatch M

    更新日期:2000-10-01 00:00:00

  • Atomoxetine and stimulants in combination for treatment of attention deficit hyperactivity disorder: four case reports.

    abstract::Atomoxetine and stimulants have both been demonstrated effective as single agents for treatment of attention deficit hyperactivity disorder in children, adolescents, and adults. However, attention deficit hyperactivity disorder symptoms in some patients do not respond adequately to single-agent treatment with these me...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/104454604773840571

    authors: Brown TE

    更新日期:2004-04-01 00:00:00

  • Neuroleptic malignant syndrome in children and adolescents: two case reports and a warning.

    abstract::ABSTRACT Neuroleptic malignant syndrome (NMS) is a potentially fatal disorder associated with the use of neuroleptics. Clinical research on NMS to date has focused exclusively on adults, but increasing numbers of juvenile cases have been reported. Two cases of juvenile NMS treated by the authors are discussed to demon...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.1992.2.123

    authors: Latz SR,McCracken JT

    更新日期:1992-07-01 00:00:00

  • Race/ethnicity and insurance status as factors associated with ADHD treatment patterns.

    abstract::Using data from the 1997-2000 Medical Expenditure Panel Survey (MEPS), disparities in different stages of attention-deficit/hyperactivity disorder (ADHD) health care were investigated, from initial detection to follow-up physician visits and psychotherapy appointments. Differences in ADHD diagnoses, stimulant usage, a...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2005.15.88

    authors: Stevens J,Harman JS,Kelleher KJ

    更新日期:2005-02-01 00:00:00

  • Sertraline treatment of 5 children diagnosed with selective mutism: a single-case research trial.

    abstract::In this single-case research study, we examined the efficacy and acceptability of sertraline treatment in children diagnosed with selective mutism. We utilized a double-blind, placebo-controlled trial of sertraline within a replicated multiple baseline/across participants research design (n = 2; n = 3). Multiple metho...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1089/cap.1999.9.293

    authors: Carlson JS,Kratochwill TR,Johnston HF

    更新日期:1999-01-01 00:00:00

  • Effectiveness of methylphenidate in the 10-month continuation phase of the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS).

    abstract:OBJECTIVE:The aim of this study was to examine immediate-release methylphenidate effectiveness during the 10-month open-label continuation phase of the Preschoolers with Attention-Deficit/Hyperactivity Disorder (ADHD) Treatment Study (PATS). METHODS:One hundred and forty preschoolers with ADHD, who had improved with a...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2007.0058

    authors: Vitiello B,Abikoff HB,Chuang SZ,Kollins SH,McCracken JT,Riddle MA,Swanson JM,Wigal T,McGough JJ,Ghuman JK,Wigal SB,Skrobala AM,Davies M,Posner K,Cunningham C,Greenhill LL

    更新日期:2007-10-01 00:00:00

  • Decreasing Trend in the Use and Long-Term Use of Benzodiazepines Among Young Adults.

    abstract:OBJECTIVE:Patterns of benzodiazepine (BZD) use and long-term use among young adults are not well known. Our aim was to study trends in BZD use and long-term use among 18-25-year-old young adults by gender and active substance in a nationwide retrospective longitudinal register-based setting. METHODS:All Finns aged 18-...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2017.0140

    authors: Tähkäpää SM,Saastamoinen L,Airaksinen M,Tuulio-Henriksson A,Aalto-Setälä T,Kurko T

    更新日期:2018-05-01 00:00:00

  • A Quantitative Comparison Approach for Methylphenidate Drug Regimens in Attention-Deficit/Hyperactivity Disorder Treatment.

    abstract:OBJECTIVE:Different methylphenidate (MPH) formulations, immediate release (IR) or extended release (ER), have been developed to treat Attention-Deficit/Hyperactivity Disorder (ADHD). A better use of these formulations, with a proper choice of their timing, dosage, and combination, can help to attain optimal therapeutic...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2018.0093

    authors: Soufsaf S,Robaey P,Bonnefois G,Nekka F,Li J

    更新日期:2019-04-01 00:00:00

  • Academic, behavioral, and cognitive effects of OROS® methylphenidate on older children with attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:To assess the effect of Osmotic-Release Oral System (OROS) methylphenidate (MPH) on a variety of measures evaluating academic performance, cognition, and social behavior in children with attention-deficit/hyperactivity disorder (ADHD). METHODS:This double-blind, randomized, placebo-controlled, crossover labo...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1089/cap.2010.0047

    authors: Wigal SB,Wigal T,Schuck S,Brams M,Williamson D,Armstrong RB,Starr HL

    更新日期:2011-04-01 00:00:00

  • Pharmacokinetics and pharmacodynamics of edivoxetine (LY2216684), a norepinephrine reuptake inhibitor, in pediatric patients with attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:Edivoxetine (LY2216684) is a selective and potent norepinephrine reuptake inhibitor (NERI). The pharmacokinetics (PK) and pharmacodynamics (PD) of edivoxetine were assessed in children and adolescent patients with attention-deficit/hyperactivity disorder (ADHD) following single and once-daily oral doses of ed...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2011.0151

    authors: Kielbasa W,Quinlan T,Jin L,Xu W,Lachno DR,Dean RA,Allen AJ

    更新日期:2012-08-01 00:00:00

  • Palpebral twitching in a depressed adolescent on citalopram.

    abstract::Current estimates suggest that between 0.4% and 8.3% of children and adolescents are affected by major depression. We report a favorable response to treatment with citalopram by a 15-year-old boy with major depression who exhibited palpebral twitching during his first 2 weeks of treatment. This may have been a side ef...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/10445460152595621

    authors: Rojas VM,Silva R

    更新日期:2001-10-01 00:00:00

  • Subjective effects, misuse, and adverse effects of osmotic-release methylphenidate treatment in adolescent substance abusers with attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:Psychostimulants are effective treatments for attention-deficit/hyperactivity disorder (ADHD) but may be associated with euphoric effects, misuse/diversion, and adverse effects. These risks are perceived by some clinicians to be greater in substance-abusing adolescents relative to non-substance-abusing adults...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章,随机对照试验

    doi:10.1089/cap.2011.0014

    authors: Winhusen TM,Lewis DF,Riggs PD,Davies RD,Adler LA,Sonne S,Somoza EC

    更新日期:2011-10-01 00:00:00

  • Maintenance study for adolescent depression.

    abstract:OBJECTIVE:Although recent studies and meta-analyses confirm the efficacy of antidepressants in the acute phase of treatment for adolescent depression, there are few data available to allow assessment of the value of continued use of antidepressants in depressed adolescents after acute response. This study examines the ...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1089/cap.2008.0001

    authors: Cheung A,Kusumakar V,Kutcher S,Dubo E,Garland J,Weiss M,Kiss A,Levitt A

    更新日期:2008-08-01 00:00:00

  • Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder.

    abstract:OBJECTIVE:The glutamatergic prefrontal-striatal pathway has been implicated previously in the neurobiology of attention-deficit/hyperactivity disorder (ADHD). We used short echo proton magnetic resonance spectroscopy (1H-MRS) to examine glutamate in the prefrontal cortex, left striatum, and, as a control area, the occi...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2006.0008

    authors: Carrey NJ,MacMaster FP,Gaudet L,Schmidt MH

    更新日期:2007-02-01 00:00:00

  • Psychometric properties of the Children's Depression Rating Scale-Revised in adolescents.

    abstract:OBJECTIVE:The aim of this study was to present the reliability and validity of the Children's Depression Rating Scale-Revised (CDRS-R) in the adolescent age group. METHOD:Adolescents with symptoms of depression were assessed using the CDRS-R and global severity and functioning scales at screening, baseline, and after ...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2010.0063

    authors: Mayes TL,Bernstein IH,Haley CL,Kennard BD,Emslie GJ

    更新日期:2010-12-01 00:00:00

  • Sudden death and tricyclic antidepressants: clinical considerations for children.

    abstract::ABSTRACT The sudden collapse and death in three prepubertal children during routine treatment with desipramine was recently reported in brief statements. Insufficient clinical information is available to infer a cause-and-effect relationship between the therapeutic use of desipramine and sudden death in these children...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.1990.1.125

    authors: Popper CW,Elliott GR

    更新日期:1990-10-01 00:00:00

  • Reboxetine as an optional treatment for hyperkinetic conduct disorder: a prospective open-label trial.

    abstract:BACKGROUND AND PURPOSE:Hyperkinetic conduct disorder (HCD) has been identified as a common psychiatric diagnosis among children and adolescents. This disorder affects many life aspects of both child and family. The aim of this study was to examine the efficacy of the selective norepinephrine reuptake inhibitor (SNRI), ...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1089/cap.2005.15.259

    authors: Mozes T,Meiri G,Ben-Amity G,Sabbagh M,Weizman A

    更新日期:2005-04-01 00:00:00

  • Guanfacine treatment of hyperactivity and inattention in pervasive developmental disorders: a retrospective analysis of 80 cases.

    abstract:OBJECTIVE:The aim of this study was to retrospectively review a large sample of children and adolescents with pervasive developmental disorders (PDDs) treated with open-label guanfacine in order to gather preliminary data as to its effectiveness and safety. METHOD:Eighty (80) subjects with PDDs (10 females, 70 males) ...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/1044546041649084

    authors: Posey DJ,Puntney JI,Sasher TM,Kem DL,McDougle CJ

    更新日期:2004-07-01 00:00:00

  • Risperidone-related improvement of irritability in children with autism is not associated with changes in serum of epidermal growth factor and interleukin-13.

    abstract::Risperidone has been shown to improve serious behavioral problems in children with autism. Here we asked whether risperidone-associated improvement was related to changes in concentrations of inflammatory molecules in the serum of these subjects. Seven molecules were identified as worthy of further assessment by perfo...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2010.0134

    authors: Tobiasova Z,van der Lingen KH,Scahill L,Leckman JF,Zhang Y,Chae W,McCracken JT,McDougle CJ,Vitiello B,Tierney E,Aman MG,Arnold LE,Katsovich L,Hoekstra PJ,Volkmar F,Bothwell AL,Kawikova I

    更新日期:2011-12-01 00:00:00

  • The Importance of Second-Generation Antipsychotic-Related Weight Gain and Adherence Barriers in Youth with Bipolar Disorders: Patient, Parent, and Provider Perspectives.

    abstract:: Objectives: The objective of this research was to understand physician, patient, and parent perspectives on barriers to second-generation antipsychotic (SGA) medication adherence in youth with bipolar spectrum disorders, and attitudes toward treatment of SGA-related weight...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2019.0184

    authors: Klein CC,Topalian AG,Starr B,Welge J,Blom T,Starr C,Deetz I,Turner H,Sage J,Utecht J,Fornari V,Patino Duran L,Higdon C,Sutton JJ,Sorter MT,Correll CU,DelBello MP

    更新日期:2020-07-01 00:00:00

  • Side effects from use of one or more psychiatric medications in a population-based sample of children and adolescents.

    abstract:OBJECTIVE:The purpose of this study was to investigate the side effect risks from using one or more psychiatric medications (including antipsychotics, antidepressants, α-2 agonists, benzodiazepines, mood stabilizers, and stimulants) among a national cohort of children and adolescents. METHODS:A questionnaire survey wa...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2013.0036

    authors: Hilt RJ,Chaudhari M,Bell JF,Wolf C,Koprowicz K,King BH

    更新日期:2014-03-01 00:00:00

  • Does comorbid depression predict subsequent adverse life events in youth with attention-deficit/hyperactivity disorders?

    abstract:OBJECTIVES:Studies have primarily focused on adverse life events (ALEs) as potential causes rather than as outcomes of pediatric depression. The current study prospectively examines ALEs in a sample of youth with attention-deficit/hyperactivity disorders (ADHD) to determine whether having a major depressive disorder (M...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2011.0046

    authors: Daviss WB,Diler R

    更新日期:2012-02-01 00:00:00

  • Relative cardiovascular safety of psychostimulants used to treat attention-deficit hyperactivity disorder.

    abstract::ABSTRACT The pertinent literature was reviewed on cardiovascular changes induced by psychostimulant medication treatment of hyperactive children. An assessment of 15 controlled studies using test doses of methylphenidate revealed a significant elevation of the resting heart rate in previously unmedicated children (mea...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.1992.2.279

    authors: Safer DJ

    更新日期:1992-01-01 00:00:00

  • Disruptive Mood Dysregulation Disorder and Bipolar Disorder Not Otherwise Specified: Fraternal or Identical Twins?

    abstract:OBJECTIVE:The purpose of this study was to examine similarities and differences between disruptive mood dysregulation disorder (DMDD) and bipolar disorder not otherwise specified (BP-NOS) in baseline sociodemographic and clinical characteristics and 36 month course of irritability in children 6-12.9 years of age. METH...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 杂志文章

    doi:10.1089/cap.2015.0062

    authors: Fristad MA,Wolfson H,Algorta GP,Youngstrom EA,Arnold LE,Birmaher B,Horwitz S,Axelson D,Kowatch RA,Findling RL,LAMS Group.

    更新日期:2016-03-01 00:00:00

  • Methylphenidate improves Stroop naming speed, but not response interference, in children with attention deficit hyperactivity disorder.

    abstract:OBJECTIVE:The goal of this study was to investigate the effect of methylphenidate (MPH) on response interference, as measured by the Stoop Color and Word Test, in children with attention deficit hyperactivity disorder (ADHD). Response interference is a core component of response inhibition that has been shown to be imp...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1089/104454602762599844

    authors: Bedard AC,Ickowicz A,Tannock R

    更新日期:2002-01-01 00:00:00

  • Effects of serotonin reuptake inhibitors on aggressive behavior in psychiatrically hospitalized adolescents: results of an open trial.

    abstract::Low concentrations of the neurotransmitter serotonin and its 5-hydroxyindoleacetic acid metabolite in the central nervous system have been associated with increased aggressive behavior in animals and humans. Controlled clinical trials of serotonin agonists in depressed adults have suggested that aggressive behavior is...

    journal_title:Journal of child and adolescent psychopharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1089/cap.1997.7.31

    authors: Constantino JN,Liberman M,Kincaid M

    更新日期:1997-04-01 00:00:00