Working memory for order information: multiple cognitive and neural mechanisms.

abstract：:The senses of hearing and balance in vertebrates are transduced by hair cells in the inner ear. Hair cells from a wide variety of organisms have been described electrophysiologically but this is the first report of the application of these techniques to the genetically tractable zebrafish model system. Auditory and ve...

journal_title：Neuroscience

authors： Haden M,Einarsson R,Yazejian B

更新日期：2013-09-17 00:00:00

abstract：:Combining gene expression data with morphological information has revolutionized developmental neuroanatomy in the last decade. Visualization and interpretation of complex images have been crucial to these advances in our understanding of mechanisms underlying early brain development, as most developmental processes a...

journal_title：Neuroscience

authors： Lindsay S,Sarma S,Martínez-de-la-Torre M,Kerwin J,Scott M,Luis Ferran J,Baldock R,Puelles L

更新日期：2005-01-01 00:00:00

abstract：:The anatomical distributions and affinity states of dopamine D1 and D2 receptors were compared in the rat central nervous system using quantitative autoradiography. [3H]SCH23390 and [3H]spiperone (in the presence of 100 nM mianserin) were used to label the D1 and D2 receptors, respectively. The densities of D1 and D2 ...

journal_title：Neuroscience

authors： Richfield EK,Penney JB,Young AB

更新日期：1989-01-01 00:00:00

abstract：:Several lines of clinical evidence support the idea that fragile X syndrome (FXS) may involve a dysregulation of hypothalamic-pituitary-adrenal axis function [Wisbeck et al. (2000) J Dev Behav Pediatr 21:278-282; Hessl et al. (2002) Psychoneuroendocrinology 27:855-872]. We had tested this idea in a mouse model of FXS ...

journal_title：Neuroscience

authors： Qin M,Xia Z,Huang T,Smith CB

更新日期：2011-10-27 00:00:00

abstract：:In animal models of transients ischemia, selective vulnerability and delayed neuronal death in the hippocampus have been extensively described. However, little is known about selective damage in the neocortex and the thalamus, even though deficits in sensorimotor function are common in humans surviving hypoxic/ischemi...

journal_title：Neuroscience

authors： Lin CS,Polsky K,Nadler JV,Crain BJ

更新日期：1990-01-01 00:00:00

abstract：:The expression pattern of pannexin1, a gene coding for a protein that forms gap junction channels, was studied as both mRNA and protein in the CNS of adult mouse. Pannexin1 was widely expressed in the CNS by neuronal cell types but not glial cells, except for Bergmann glial cells of the cerebellar cortex. Cells positi...

journal_title：Neuroscience

authors： Zappalà A,Cicero D,Serapide MF,Paz C,Catania MV,Falchi M,Parenti R,Pantò MR,La Delia F,Cicirata F

更新日期：2006-08-11 00:00:00

abstract：:To examine changes in corticostriatal synaptic transmission in rats with ethanol withdrawal syndrome, intracellular and extracellular responses to subcortical white matter stimulation were recorded in neostriatal slice preparations. The resting membrane potential, input resistance and depolarizing postsynaptic potenti...

journal_title：Neuroscience

authors： Yamamoto Y,Nakanishi H,Takai N,Shimazoe T,Watanabe S,Kita H

更新日期：1999-01-01 00:00:00

abstract：:Considerable evidence suggests that a dysfunction of the dopamine and serotonin (5-hydroxytryptamine or 5-HT) neurotransmitter systems contributes to a diverse range of pathological conditions including schizophrenia, depression and drug abuse. Recent electrophysiological and behavioral studies suggest that 5-HT modul...

journal_title：Neuroscience

authors： Nocjar C,Roth BL,Pehek EA

更新日期：2002-01-01 00:00:00

abstract：:Voltage-gated Ca2+ channels (VGCCs) play key roles in auditory perception and information processing within the inner ear and brainstem. Pharmacological inhibition of low voltage-activated (LVA) T-type Ca2+ channels is related to both age- and noise induced hearing loss in experimental animals and may represent a prom...

journal_title：Neuroscience

authors： Lundt A,Seidel R,Soós J,Henseler C,Müller R,Bakki M,Arshaad MI,Ehninger D,Hescheler J,Sachinidis A,Broich K,Wormuth C,Papazoglou A,Weiergräber M

更新日期：2019-06-15 00:00:00

abstract：:Cholecystokinin-like immunoreactivity was investigated with an indirect immunoperoxidase technique in the whole spinal cord with the light microscope and in the dorsal horn with the electron microscope. Intraparenchymal injections of colchicine were performed to allow the detection of cholecystokinin-like immunoreacti...

journal_title：Neuroscience

authors： Conrath-Verrier M,Dietl M,Tramu G

更新日期：1984-11-01 00:00:00

abstract：:Ciliary neurotrophic factor is known to exert both survival and differentiative actions on a number of neuronal populations of the peripheral and central nervous systems. In this study we have compared the trophic effects of ciliary neurotrophic factor and nerve growth factor on developing septal neurons of the rat in...

journal_title：Neuroscience

authors： Kew JN,Sofroniew MV

更新日期：1995-06-01 00:00:00

abstract：:The distribution and origin of nerves with calcitonin gene-related peptide, substance P or neurokinin A immunoreactivity in the walls of the cerebral arteries were investigated in three microchiropteran species. The supply of nerves immunoreactive for substance P and neurokinin A to the bat cerebral arteries is confin...

journal_title：Neuroscience

authors： Ando K,Arai S,Kawamura K

更新日期：1990-01-01 00:00:00

abstract：:Components of the brain's dopaminergic system, such as dopamine receptors, undergo final maturation in adolescence. Exposure to social stress during human adolescence contributes to substance abuse behaviors. We utilized a rat model of adolescent social stress to investigate the neural mechanisms underlying this corre...

journal_title：Neuroscience

authors： Burke AR,Watt MJ,Forster GL

更新日期：2011-12-01 00:00:00

abstract：:Intracellular recordings were made from neurons in a rat locus coeruleus slice preparation in vitro. A postsynaptic potential was evoked by electrical stimulation of afferents to the neurons. CI-977 ([5R-(5a,7a,8b)]-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec -8-yl[-4-benzofuranacetamide monohydrochloride) cause...

journal_title：Neuroscience

authors： Pinnock RD

更新日期：1992-01-01 00:00:00

abstract：:Lower motor neuron dysfunction is one of the most debilitating neurological conditions and, as such, significantly impacts on the quality of life of affected individuals. Within the last decade, the engineering of mouse models of lower motor neuron diseases has facilitated the development of new therapeutic scenarios ...

journal_title：Neuroscience

authors： Mohan R,Tosolini AP,Morris R

更新日期：2014-08-22 00:00:00

abstract：:The study of architectonic differentiation in the cortex is advanced by the articulation of objective definitions based on clear features of the cortical architecture. We adopted areal density profiles as a means of sampling the cortex. On the profiles, we isolated and quantified the density of individual cortical lay...

journal_title：Neuroscience

authors： Mackey S,Petrides M

更新日期：2009-03-31 00:00:00

abstract：:Although intrathecal administration of nociceptin, an endogenous ligand of the opioid receptor-like1 receptor, exhibits an antinociceptive effect in various pain models, cellular mechanisms underlying this action are still unknown. Here, we investigated the effects of nociceptin on excitatory and inhibitory synaptic t...

journal_title：Neuroscience

authors： Luo C,Kumamoto E,Furue H,Chen J,Yoshimura M

更新日期：2002-01-01 00:00:00

abstract：:The present study set out to assess the possible role of the medial prefrontal cortex (mPFC) cannabinoid CB1 receptors and BDNF/cFOS signaling pathways in morphine-dextromethorphan (DXM) cross state-dependent memory (SDM) using male Wistar rats. Changes on the levels of BDNF and cFOS proteins in the PFC were examined ...

journal_title：Neuroscience

authors： Ghasemzadeh Z,Rezayof A

更新日期：2018-11-21 00:00:00

abstract：:The ototoxic side-effects of the anti-cancer drug cisplatin (cis-diaminedichloroplatinum) have been widely investigated. However, the exact site of action remains unclear. In this study, the electroreceptor organ of the freshwater catfish Ictalurus melas is used as a model for examining the acute effects of cisplatin....

journal_title：Neuroscience

authors： Peters RC,Mommersteeg PM,Heijmen PS

更新日期：1999-01-01 00:00:00

abstract：:Accumulating evidences indicate that ceramide is closely involved in apoptotic cell death in neurodegenerative disorders and aging. We examined ceramide levels in the cerebrospinal fluid (CSF) or brain tissues from patients with neurodegenerative disorders and the mechanism of how intra- and extracellular ceramide was...

journal_title：Neuroscience

authors： Satoi H,Tomimoto H,Ohtani R,Kitano T,Kondo T,Watanabe M,Oka N,Akiguchi I,Furuya S,Hirabayashi Y,Okazaki T

更新日期：2005-01-01 00:00:00

abstract：:Repeated administration of amphetamine-like psychostimulants produce a progressive and long-lasting hypersensitivity to their behavioural effects known as behavioural sensitization. Previous studies have shown that administration of the purinergic P2 receptor agonist 2-methylthio ATP into the nucleus accumbens of rats...

journal_title：Neuroscience

authors： Kittner H,Krügel U,Illes P

更新日期：2001-01-01 00:00:00

abstract：:Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived. Recent evidence supports the hypothesis that tinnitus is related to neuronal hyperactivity in auditory brain regions, and consequently drugs that increase GABAergic neurotransmission in the CNS, such as the GABA(B) receptor a...

journal_title：Neuroscience

authors： Zheng Y,McPherson K,Smith PF

更新日期：2014-01-31 00:00:00

abstract：:Chronic ethanol consumption increases oxidative stress, which accounts for the striking neurological changes seen in this condition. Notwithstanding, there is well-documented evidence that polyphenols, present in grape skin and seeds, exhibit a strong antioxidant activity. As red wine is rich in polyphenols, the aim o...

journal_title：Neuroscience

authors： Assunção M,Santos-Marques MJ,de Freitas V,Carvalho F,Andrade JP,Lukoyanov NV,Paula-Barbosa MM

更新日期：2007-06-08 00:00:00

abstract：:The lurcher mutation induces Purkinje cell degeneration in heterozygous mice, and neonatal death in homozygous animals. Using the D6Mit16 Simple Sequence Length Polymorphic marker in F2 hybrids between AKR +/+ mice and B6+/Lc mice, homozygous lurcher fetuses and newborns as well as heterozygous and normal littermates ...

journal_title：Neuroscience

authors： Resibois A,Cuvelier L,Goffinet AM

更新日期：1997-09-01 00:00:00

abstract：:In the diurnal unstriped Nile grass rat (Arvicanthis niloticus) access to a running wheel can trigger a shift in active phase preference, with some individuals becoming night-active (NA), while others continue to be day-active (DA). To investigate the contributions of different neural systems to the support of this sh...

journal_title：Neuroscience

authors： Castillo-Ruiz A,Nixon JP,Smale L,Nunez AA

更新日期：2010-01-20 00:00:00

abstract：:The neurosensory cells of the primary olfactory and vomeronasal projections are in a state of continuous replacement throughout adult life. Since their axons form synaptic terminals with neurons in the olfactory and accessory olfactory bulbs, this system is an apparent exception to the rule that peripheral axons canno...

journal_title：Neuroscience

authors： Raisman G

更新日期：1985-01-01 00:00:00

abstract：:The nucleus of the solitary tract is the site of termination of primary afferent fibers running in the facial, glossopharyngeal and vagus nerves. The present study was performed to map the distribution of glutamatergic axons terminals in the rat nucleus of the solitary tract using immunodetection of vesicular glutamat...

journal_title：Neuroscience

authors： Lachamp P,Crest M,Kessler JP

更新日期：2006-01-01 00:00:00

abstract：:It is well established that chronic food restriction enhances sensitivity to the rewarding and motor-activating effects of abused drugs. However, neuroadaptations underlying these behavioral effects have not been characterized. The purpose of the present study was to explore the possibility that food restriction produ...

journal_title：Neuroscience

authors： Carr KD,Tsimberg Y,Berman Y,Yamamoto N

更新日期：2003-01-01 00:00:00

abstract：:Using spinal cord and dorsal root ganglion cell cultures, we have studied the immuno-histochemical distribution of several peptide products of the dynorphin gene. With antibody directed toward the midregion of dynorphin A, peptide-immunoreactivity was found exclusively in the cell bodies of spinal cord neurons. Antibo...

journal_title：Neuroscience

authors： Sweetnam PM,Wrathall JR,Neale JH

更新日期：1986-08-01 00:00:00

abstract：:The Ts65Dn mouse model of Down syndrome (DS) and Alzheimer's disease (AD) exhibits cognitive impairment and degeneration of basal forebrain cholinergic neurons (BFCNs). Our prior studies demonstrated that maternal choline supplementation (MCS) improves attention and spatial cognition in Ts65Dn offspring, normalizes hi...

journal_title：Neuroscience

authors： Powers BE,Kelley CM,Velazquez R,Ash JA,Strawderman MS,Alldred MJ,Ginsberg SD,Mufson EJ,Strupp BJ

更新日期：2017-01-06 00:00:00