Abstract:
:This study aimed to investigate periapical exudate neutrophil elastase (NE) and prostaglandin E2 (PGE2) levels and their relationships with clinical symptoms, and to determine the changes of their levels following first treatment visit. Periapical exudate samples were collected from the canals of 34 nonvital single-rooted teeth at two sequential treatment visits. Periapical exudate NE and PGE2 levels were found to be higher in the presence of clinical symptoms (pus discharge, swelling) (p < 0.05). The canals of teeth with larger periapical radiolucent area (>or=1 cm) contained more PGE2 levels than with smaller ones (<1 cm) (p < 0.05). Periapical exudate NE levels were significantly correlated with PGE2 levels (p < 0.05), and their levels at first treatment visit did not change following root canal therapy (p > 0.05). The periapical exudate NE and PGE2 levels may regulate periapical disease expression, but the results of this study were unable to reveal this association.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Alptekin NO,Ari H,Haliloglu S,Alptekin T,Serpek B,Ataoglu Tdoi
10.1097/01.don.0000158010.43884.59keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
791-5issue
11eissn
0099-2399issn
1878-3554pii
S0099-2399(06)61078-9journal_volume
31pub_type
杂志文章abstract:INTRODUCTION:The purpose of this study was to evaluate the influence of pH that is due to setting reaction of Biodentine, glass ionomer cement (GIC), and intermediate restorative material (IRM) on transforming growth factor-β1 (TGF-β1) release and on the fibrin architecture of platelet-rich fibrin (PRF). METHODS:PRF w...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2016.02.009
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:The direct effect of follicle-stimulating hormone (FSH) on bone resorption has been demonstrated recently. The aim of this study was to evaluate the effect of FSH inhibitor leuprorelin (LE) on alveolar bone loss resulting from experimental periapical lesions in ovariectomized (OVX) rats. METHODS:Twenty-se...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2010.01.011
更新日期:2010-04-01 00:00:00
abstract::Biopsy reports of specimens from the apices of 1659 teeth physically present at the time the biopsy was performed were reviewed. The following information was recorded from each report: (a) source of specimen, (b) sex of patient, (c) age of patient, (d) location of tooth associated with lesion, and (e) diagnoses repor...
journal_title:Journal of endodontics
pub_type: 杂志文章,评审
doi:10.1016/s0099-2399(06)81679-1
更新日期:1990-05-01 00:00:00
abstract::The aim of this study was to investigate the correlation between endodontic clinical signs and symptoms and the presence of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia or their association by nested polymerase chain reaction assay. Microbial samples were taken from 50 cases with necrotic pu...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2007.05.017
更新日期:2007-09-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to examine the effect of mineral trioxide aggregate (MTA) on pluripotent-mesenchymal cell differentiation. METHODS:The pluripotent-mesenchymal cell line C2C12 was cultured in a 5% serum medium to induce cell differentiation with or without MTA. The differentiation to myoblast...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2012.10.006
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:It has been widely accepted that dental pulp stem cells (DPSCs), which are a class of self-renewal and differentiation potential of adult stem cells, play an important role in the repair procession of pulp's inflammation. We investigated whether tumor necrosis factor alpha (TNF-α) could induce the prolifer...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2015.02.020
更新日期:2015-07-01 00:00:00
abstract::Orthodontic tooth movement has been implicated in secondary changes to the dental pulp. The purpose of this study was to correlate the effects of orthodontic tooth movement on the dental pulp by histomorphometric parameters. Four groups, each consisting of 36 male adult Sprague-Dawley strain rats, were studied with di...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/S0099-2399(06)81034-4
更新日期:1993-01-01 00:00:00
abstract::The mesiobuccal roots of 50 randomly selected maxillary first molars were examined to assess the incidence and position of the canal isthmus. Transverse serial sections of the apical 6 mm of each root were prepared in 1-mm increments. The apical side of each section was stained with methylene blue dye, viewed with a s...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/s0099-2399(06)80975-1
更新日期:1995-07-01 00:00:00
abstract::The bond strength of ActiV GP root canal filling system and gutta-percha/AH plus sealer when used after final rinse with different irrigation protocols was evaluated in this study. Forty roots were randomly divided into four groups (n = 10) according to the final irrigation regimen: group 1, 5 mL 17% EDTA; group 2, 5 ...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2009.01.003
更新日期:2009-04-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to evaluate the push-out bond strengths of different obturating materials. METHODS:Forty single-rooted human extracted teeth were used in this study. The teeth were instrumented and irrigated by using 5.25% NaOCl, 15% ethylenediaminetetraacetic acid, and sterile water. The te...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2009.10.026
更新日期:2010-02-01 00:00:00
abstract::Terrein is a bioactive fungal metabolite whose anti-inflammatory properties are virtually unknown. The purpose of this study was to determine the effects of terrein on lipopolysaccharide (LPS)-induced expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in human denta...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2008.01.015
更新日期:2008-04-01 00:00:00
abstract::The purpose of this study was to determine the influence of operator experience on the ability to locate and fill extra canals in maxillary first and second molars in vivo. The number of canals located and filled from maxillary first and second molars was recorded from three endodontic residents during the first 6 mon...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2005.11.005
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:The purpose of this in vitro study was to compare the cytotoxicity of white mineral trioxide aggregate cement (AMTA, MTA-Angelus), Brasseler Endosequence Root Repair Putty (ERRM), Dycal, and Ultra-blend Plus (UBP) by using human dermal fibroblasts and a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium ...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2011.11.012
更新日期:2012-03-01 00:00:00
abstract:INTRODUCTION:The pulpal anesthetic success rates for an inferior alveolar nerve block (IANB) alone in patients presenting with symptomatic irreversible pulpitis are less than adequate. Nitrous oxide and clonidine have shown increases in IANB success when administered individually, but their success has not been evaluat...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2020.12.014
更新日期:2020-12-30 00:00:00
abstract:INTRODUCTION:This study aimed to evaluate the frequency of dentinal microcracks observed after root canal preparation with 2 reciprocating and a conventional full-sequence rotary system using micro-computed tomographic analysis. METHODS:Thirty mesial roots of mandibular molars presenting a type II Vertucci canal confi...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2014.02.019
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to investigate the influence of apical filling material and the modification made to the apical preparation design in surgical endodontics on the areas of stress concentration in the mesial root of a mandibular molar using finite element analysis. METHODS:The filling material was...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2019.12.007
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Resin-based dental materials contain various diluent monomers that can interfere with vascular function by causing vasodilation. In this study, we evaluated the vasoactive potential of hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) and the possible mechanism of their vascul...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2010.11.038
更新日期:2011-03-01 00:00:00
abstract::Ocular complications after an inferior alveolar nerve anesthesia are rare. These complications, although temporary and benign, can be distressing to both the patient and the clinician. A 37-year-old male patient was administered an inferior alveolar nerve block for the root canal treatment of tooth #30. Immediately af...
journal_title:Journal of endodontics
pub_type: 杂志文章,评审
doi:10.1016/j.joen.2018.05.005
更新日期:2018-09-01 00:00:00
abstract::This in vitro study was carried out to determine (1) the hydrophobicity of selected oral bacteria, (2) the influence of growth media (saliva and serum) and mode of growth (planktonic or biofilm) on the hydrophobicity of Enterococcus faecalis, and (3) the influence of growth media and conditioning fluids on the adheren...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2007.07.035
更新日期:2007-12-01 00:00:00
abstract::Previous dye leakage studies have shown that mineral trioxide aggregate leaks significantly less than other commonly used root-end filling materials. This study determined the time needed for Staphylococcus epidermidis to penetrate a 3-mm thickness of amalgam, Super-EBA, Intermediate Restorative Material (IRM), or min...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/s0099-2399(06)80433-4
更新日期:1995-03-01 00:00:00
abstract:INTRODUCTION:Vertical root fractures (VRFs) are among the most frequent causes of tooth loss, mainly of endodontically treated teeth. However, very few data is available about the occurrence of VRFs following apical surgery. METHODS:Patient charts from 864 patients with 1058 teeth treated with apical surgery (Septembe...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2020.10.012
更新日期:2021-02-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to compare the cell viability of dental pulp cells treated with Biodentine (Septodont, Saint-Maur, France) and mineral trioxide aggregate (MTA) and the in vitro and in vivo expression of mineralization markers induced by the 2 materials. METHODS:Human dental pulp cells isolat...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2015.12.018
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:A 3-antibiotic combination (3Mix) has been widely used in regenerative endodontics. Recent studies recommend that a safe concentration of 3Mix is in the range of 0.39 μg/mL and 1 mg/mL because higher concentrations may limit tissue regeneration. The aim of this study was to determine the regenerative capac...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2013.09.027
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Root resorption is a common complication after replantation following traumatic dental avulsion. Endodontic therapy combined with local and intracanal medications aims to avoid osteoclastic activity. In such cases, the application of alendronate (ALN), a bisphosphonate widely used for the treatment of bone...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2014.07.010
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:This study evaluated the physicochemical, antimicrobial, and biological properties of white mineral trioxide aggregate (MTA) mixed with aqueous and propylene glycol extracts of Arctium lappa L. and Casearia sylvestris Sw. METHODS:The setting-time test was performed according to American Society for Testin...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2016.12.023
更新日期:2017-05-01 00:00:00
abstract::The objective of this study was to compare the effectiveness of F-files and ultrasonics to remove the smear layer from instrumented root canals when irrigated with sodium hypochlorite and EDTA. Sixty healthy human premolar teeth were instrumented with ProTaper file series to F3, and the canals were enlarged with Profi...
journal_title:Journal of endodontics
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.joen.2008.07.006
更新日期:2008-10-01 00:00:00
abstract:INTRODUCTION:The aim was to present a novel surgical technique using virtually preplanned 3-dimensional (3D)-printed templates for guided osteotomies. These were to ensure atraumatic uncovering of a severely impacted donor tooth including guided drilling of the recipient alveolus followed by a secure autotransplantatio...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2020.07.024
更新日期:2020-07-29 00:00:00
abstract:INTRODUCTION:This study aimed to investigate the roles of ephrinB2 in stabilizing vascularlike structures generated by stem cells from apical papilla (SCAPs) and human umbilical vein endothelial cells (HUVECs). METHODS:HUVECs were seeded alone or with SCAPs concurrently or 12 hours later. Angiogenesis and ephrinB2 pho...
journal_title:Journal of endodontics
pub_type: 杂志文章
doi:10.1016/j.joen.2016.05.012
更新日期:2016-09-01 00:00:00
abstract::The present study evaluates the morphological changes in root canal walls and temperature changes at root surfaces as a result of intracanal irradiation by erbium,chromium:YSGG laser under various conditions in vitro. Sixty single-rooted human teeth were examined. Root canals were prepared, and laser irradiation was p...
journal_title:Journal of endodontics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004770-200101000-00003
更新日期:2001-01-01 00:00:00
abstract::Twenty-five extracted human maxillary central incisors were randomly divided into five equal groups. Crowns were removed 1 mm incisal to the cementoenamel junction. Endodontic treatment was carried out and each tooth was affixed with two strain gauges. The strain gauge wires were connected to a Wheatstone Bridge circu...
journal_title:Journal of endodontics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0099-2399(07)80136-1
更新日期:1991-09-01 00:00:00