Deoxyribonuclease activity in T and B lymphocytes of haemodialysed patients with uraemia.

Abstract:

:Deoxyribonuclease (DNase) activity and metal ion concentrations in lymphocytes of patients with chronic renal failure and in healthy controls were studied. The data suggest that T and B lymphocyte nuclei of patients with renal failure show increased DNase activity when compared to their healthy counterparts. It is suggested that the enhancement of enzyme activity is a result of increased metal ion concentration rather than increased enzyme copy count. The data strongly suggest that haemodialysis of uraemic patients is more effective for improvement of lymphocyte metabolism than the conservative chemical treatment.

journal_name

Int Urol Nephrol

authors

Adamiec R,Szewczyk Z,Szopa J

doi

10.1007/BF02552124

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

95-101

issue

1

eissn

0301-1623

issn

1573-2584

journal_volume

24

pub_type

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