Abstract:
:A screening study was conducted to examine the effect of a series of synthesized pyrazoloquinoline derivatives on the growth of Leishmania donovani promastigotes. Sixteen compounds were tested, ten of which showed an inhibitory effect on the growth of promastigotes. Compound 1 demonstrated potent antileishmanial activity, followed by compounds 3 and 7. Some compounds showed less significant activities, while others exhibited little or no activity. Some of these compounds may be potential candidates for future treatment of leishmaniasis.
journal_name
Arch Pharm (Weinheim)journal_title
Archiv der Pharmazieauthors
Al-Qahtani A,Siddiqui YM,Bekhit AA,El-Sayed OA,Aboul-Enein HY,Al-Ahdalb MNdoi
10.1002/ardp.200500147keywords:
subject
Has Abstractpub_date
2005-10-01 00:00:00pages
484-7issue
10eissn
0365-6233issn
1521-4184journal_volume
338pub_type
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