Abstract:
:At the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) New Approaches Conference, a discussion group focused on directions for future research that are critical to enhancing our understanding of the distinctions among key cognitive domains that have relevance for the development of cognition-enhancing interventions. One set of recommendations emphasizes the need for examining and optimizing the psychometric properties of relevant measurement paradigms from cognitive psychology and cognitive neuroscience. This step is critical to translating many notable advances in these basic fields into measures that would be appropriate for clinical trials. A second set of recommendations focuses on key directions for the development and application of animal models of cognitive processes that would greatly aid the discovery and preclinical testing of potential cognition-enhancing agents. As part of this process, the group noted several existing animal paradigms that have particular promise as measures in the key cognitive domains in schizophrenia identified by the MATRICS Neurocognition Committee.
journal_name
Schizophr Bulljournal_title
Schizophrenia bulletinauthors
Nuechterlein KH,Robbins TW,Einat Hdoi
10.1093/schbul/sbi047keywords:
subject
Has Abstractpub_date
2005-10-01 00:00:00pages
870-4issue
4eissn
0586-7614issn
1745-1701pii
sbi047journal_volume
31pub_type
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