Modelling survivorship kinetics: a two-parameter model.

abstract：INTRODUCTION:The identification of modifiable health span-promoting factors is a public health priority. OBJECTIVE:To explore the socio-environmental, lifestyle, behavioural, and psychological determinants of a clinical phenotypic measure of biological ageing in the Singapore Longitudinal Ageing Study (SLAS) cohort. ...

journal_title：Gerontology

authors： Ng TP,Zhong X,Gao Q,Gwee X,Chua DQL,Larbi A

更新日期：2020-01-01 00:00:00

abstract：:The glucose uptake of lizard brain slices decreased between young and middle-aged groups. There was a significant increase in the parameter between the middle-aged and old-age groups. Cold shock induced a decrease in glucose uptake of brain slices in the old, with no appreciable effect in the young and middle aged. ...

journal_title：Gerontology

authors： Dash BD,Patnaik BK

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Previous extensive clinical studies, using angiography or ultrasound, investigated the influence of alimentary, medicamentous and other antiatherosclerotic measures on the degree of atherosclerosis. The following signs of regression were found: clinical improvement, changes in tonus of vascular walls, format...

journal_title：Gerontology

authors： Kunz J

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:There is concern that people living in residential care in Australia make significant and often inappropriate use of acute in-patient hospital services. To date, no factual information has been collected in Australia and its absence may allow myths and negative stereotypes to proliferate. OBJECTIVE:To deter...

journal_title：Gerontology

authors： Finucane P,Wundke R,Whitehead C,Williamson L,Baggoley C

更新日期：2000-05-01 00:00:00

abstract：:Research into the aetiology of osteoarthritis has for several decades been concentrated on the destruction of the articular cartilage, the initiating events being believed to be changes in the proteoglycans and subsequently in the supporting collagenous framework, whereafter the disease is irreversible. Recent evidenc...

journal_title：Gerontology

authors： Bailey AJ,Mansell JP

更新日期：1997-01-01 00:00:00

abstract：:Neuron density, volume of the area and total neuron number were measured in the medial preoptic area, supraoptic nucleus, paraventricular nucleus, anterior hypothalamic area, ventromedial nucleus, dorsomedial nucleus and arcuate nucleus of the hypothalamus in young adult male rats (3.5-5 months old) and in old male ra...

journal_title：Gerontology

authors： Peng MT,Hsü HK

更新日期：1982-01-01 00:00:00

abstract：:In the United States, an increasing proportion of all forms of reactivation tuberculosis occurs in patients over the age of 60 years. Atypical presentations and presence of chronic illness obscure the diagnosis of tuberculosis in the elderly. Prompt diagnosis requires a high index of suspicion and aggressive procedure...

journal_title：Gerontology

authors： Nagami P,Yoshikawa TT

更新日期：1984-01-01 00:00:00

abstract：:The vascular system of 30 old asymptomatic patients (average age 62.5 years) was studied by reflection plethysmography. The plethysmogram (PTG) was recorded from the forefinger of the left hand at rest, during two postural tests (+45 degrees arm-up and -45 degrees arm-down), after physical work, and during the infusio...

journal_title：Gerontology

authors： Strozzi C,Cocco G,Destro A,Padovan G,Abbasciano V,Tosatti S

更新日期：1979-01-01 00:00:00

abstract：:We examined the presenting features, clinical course and prognosis in relation to age in 121 patients with primary biliary cirrhosis (PBC) for a mean follow-up of 4.6 years. 35 patients (29%) were over age 65 years at presentation/detection. There was a higher proportion of patients asymptomatic of liver disease in th...

journal_title：Gerontology

authors： Lehmann AB,Bassendine MF,James OF

更新日期：1985-01-01 00:00:00

abstract：:Sarcopenia is a complex and multifactorial disease that includes a decrease in the number, structure and physiology of muscle fibers, and age-related muscle mass loss, and is associated with loss of strength, increased frailty, and increased risk for fractures and falls. Treatment options are suboptimal and consist of...

journal_title：Gerontology

authors： Naranjo JD,Dziki JL,Badylak SF

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Falls are a major cause of morbidity among older people. Multifaceted interventions may be effective in preventing falls and related fractures. OBJECTIVE:To evaluate the cost-effectiveness alongside the REducing Falls with Orthoses and a Multifaceted podiatry intervention (REFORM) trial. METHODS:REFORM was...

journal_title：Gerontology

authors： Corbacho B,Cockayne S,Fairhurst C,Hewitt CE,Hicks K,Kenan AM,Lamb SE,MacIntosh C,Menz HB,Redmond AC,Rodgers S,Scantlebury A,Watson J,Torgerson DJ,on behalf of the REFORM study.

更新日期：2018-01-01 00:00:00

abstract：:Historically, family ties have been understood as the primary source of support for aging adults, and past empirical and theoretical work has highlighted the tendency of older adults to focus on close family. However, in line with demographic changes and historical increases in the diversity of social structures, frie...

journal_title：Gerontology

authors： Fiori KL,Windsor TD,Huxhold O

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The total cholesterol concentration decreases with age in older people. The reasons for this phenomenon are controversial. This study investigated the hypothesis that poor health status is a determinant of the inverse association between age and cholesterol in older persons. METHODS:Cross-sectional study of...

journal_title：Gerontology

authors： Volpato S,Zuliani G,Guralnik JM,Palmieri E,Fellin R

更新日期：2001-01-01 00:00:00

abstract：:The last 2 decades have brought an explosion of research, new products, and general attention to the problem of urinary urgency, and yet patients continue to be plagued by this symptom - especially the elderly. What is it? What does it mean? How can we guide patients successfully through this challenge? This paper pre...

journal_title：Gerontology

authors： Potts JM,Payne CK

更新日期：2018-01-01 00:00:00

abstract：:The immunocompetence of 22 subjects aged 85-104 years (mean 90 +/- 1 years) was studied and compared to 21 young subjects aged 19-37 years (mean 30 +/- 1 years). The absolute lymphocyte number and the percentage of T and B lymphocytes in the peripheral blood was similar in the two groups. A marked decrease in phytohem...

journal_title：Gerontology

authors： Licastro F,Tabacchi PL,Chiricolo M,Parente R,Cenci M,Barboni F,Franceschi C

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Constipation and lower urinary tract symptoms (LUTS) very frequently occur in the elderly, and several reports have suggested that dysfunction in either one of these systems may affect the other. Most studies correlating rectal and bladder dysfunction, however, have been carried out in children or young wome...

journal_title：Gerontology

authors： Charach G,Greenstein A,Rabinovich P,Groskopf I,Weintraub M

更新日期：2001-03-01 00:00:00

abstract：:Because the body composition effects of growth hormone and insulin-like growth factor-I (IGF-I) are opposite to those of advancing age, it has been hypothesized that the decreased activity of the growth hormone-IGF-I axis is partly responsible for the loss of bone and muscle mass that characterizes normal human aging....

journal_title：Gerontology

authors： Boonen S,Lesaffre E,Aerssens J,Pelemans W,Dequeker J,Bouillon R

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The perioperative assessment and management of elderly patients with hip fracture and significant aortic stenosis (AS) is an increasingly common clinical problem with little data available to guide perioperative management. OBJECTIVES:It was the aim of this study to examine the incidence of perioperative ev...

journal_title：Gerontology

authors： Leibowitz D,Rivkin G,Schiffman J,Rott D,Weiss AT,Mattan Y,Kandel L

更新日期：2009-01-01 00:00:00

abstract：:The article discusses some aspects demonstrating that a decrease in acetylcholine synthesis in senile dementia of the Alzheimer type (SDAT) is a consequence of the strong decline in glucose turnover in the brain. This becomes obvious by the fact that acetylcoenzyme A, the key substrate of acetylcholine synthesis, is e...

journal_title：Gerontology

authors： Meier-Ruge W,Bertoni-Freddari C,Iwangoff P

更新日期：1994-01-01 00:00:00

abstract：:The concentration of malonaldehyde (MDA) was measured in human erythrocytes obtained from subjects suffering from senile dementia of the Alzheimer type (SDAT), non-demented elderly subjects, and from young controls by two methods: high-performance liquid chromatography (HPLC) and the thiobarbituric acid (TBA) test. Th...

journal_title：Gerontology

authors： Bermejo P,Gómez-Serranillos P,Santos J,Pastor E,Gil P,Martín-Aragón S

更新日期：1997-01-01 00:00:00

abstract：:(Na+-K+)-ATPase is an enzyme responsible for ionic homeostasis in excitable tissues. Thus, the activity of this enzyme is essential for the maintenance of optimal function of the cerebral cortex. Although abnormalities of cerebral oxidative metabolism have been described in aging, these abnormalities do not appear to ...

journal_title：Gerontology

authors： LaManna JC,Doull G,McCracken K,Harik SI

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Cardiac surgery is widely believed to be an excessively high-risk intervention for very elderly patients with coronary artery or valvular disease. However, as life expectancy and the prospect of sustained quality of life into older age increase, this assumption should be challenged so that surgery is not den...

journal_title：Gerontology

authors： Guilfoyle MR,Drain AJ,Khan A,Ferguson J,Large SR,Nashef SA

更新日期：2010-01-01 00:00:00

abstract：:Dementia is a symptom of a variety of specific structural brain diseases as well as several system degenerations. Alzheimer's disease presently is the commonest cause in the developed world, causing a cortical-subcortical degeneration of ascending cholinergic neurons and large pyramidal cells in the cerebral cortex. C...

journal_title：Gerontology

authors： Plum F

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:The prevalence of aortic stenosis is nearly 20% in octogenarians. Aortic valve replacement (AVR) is the optimal therapy choice, yet many symptomatic patients are denied this beneficent technology. Whether mechanical or bioprosthetic, aortic valves are not a scarce resource and their safety, effectiveness and...

journal_title：Gerontology

authors： Bramstedt KA

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Functional status in older people is a dynamic situation, which makes it necessary to evaluate functional capacity at different times to determinate their prognostic value. OBJECTIVE:To examine the association between functional status (baseline and change after acute illness) and mortality and functional c...

journal_title：Gerontology

authors： Baztán JJ,Gálvez CP,Socorro A

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To examine the relationships between upper extremity function (UEF) and mortality, need for social assistance and change of residence, at discharge from hospital and at 1 month following discharge. METHODS:Observational, cohort study. SETTING:Acute Geriatric Unit of a Tertiary Teaching Hospital. SUBJECTS:3...

journal_title：Gerontology

authors： Abizanda P,Navarro JL,Romero L,León M,Sánchez-Jurado PM,Domínguez L

更新日期：2007-01-01 00:00:00

abstract：:Antinuclear antibodies, anticardiolipin antibodies and IgM rheumatoid factor were determined in 300 healthy aged subjects, comparing their prevalence to that in 100 healthy subjects aged between 19 and 44 years and 352 patients under 65 years of age, affected by various systemic rheumatic diseases. Increased productio...

journal_title：Gerontology

authors： Ruffatti A,Rossi L,Calligaro A,Del Ross T,Lagni M,Marson P,Todesco S

更新日期：1990-01-01 00:00:00

abstract：:Anaerobic bacteremia occurred in 68 patients over the age of 60 in a university hospital. These elderly patients were more likely than younger patients to have an underlying malignancy. Anaerobes involved included Bacteroides fragilis group (64 isolates), Bacteroides melaninogenicus group (11) and Clostridium species ...

journal_title：Gerontology

authors： Terpenning MS

更新日期：1989-01-01 00:00:00

abstract：:The Hermansky-Pudlak syndrome (HPS) is an autosomal recessive disease characterized by a triad of oculocutaneous albinism, accumulation of auto-fluorescent ceroid-like pigments within macrophages, and bleeding tendency due to a storage pool disease of the platelets. We report an autopsy case (39y, male), who died of p...

journal_title：Gerontology

authors： Ohbayashi C,Kanomata N,Imai Y,Ito H,Shimasaki H

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Old age has traditionally been considered to begin at age 65. The improving health and functional status observed among older people may necessitate reevaluation of this cut-off point. OBJECTIVE:To present the changing prevalence of common geriatric syndromes, functional parameters, common disease status an...

journal_title：Gerontology

authors： Jacobs JM,Maaravi Y,Cohen A,Bursztyn M,Ein-Mor E,Stessman J

更新日期：2012-01-01 00:00:00