X-ray analysis of Co-C bond cleavage in the crystalline state.

Abstract:

:During serial structure analysis of cobaloxime derivatives, aimed at interpreting the catalytic capability of the asymmetric hydrogenation, we have found that the crystal of R-alpha-cyanoethyl (S-alpha-methylbenzylamine)-cobaloxime changes its unit cell dimensions by X-ray exposure without degradation of a single crystal form. The rate of the change was so slow that it was possible to collect the intensity data for several intermediate stages. We have proved, by calculating electron density in each stage, that the change reflects the racemisation of the cyanoethyl group.

journal_name

Nature

journal_title

Nature

authors

Ohashi Y,Sasada Y

doi

10.1038/267142a0

keywords:

subject

Has Abstract

pub_date

1977-05-12 00:00:00

pages

142-4

issue

5607

eissn

0028-0836

issn

1476-4687

pii

267142a0

journal_volume

267

pub_type

杂志文章

相关文献

NATURE文献大全
  • The DIX domain targets dishevelled to actin stress fibres and vesicular membranes.

    abstract::Colorectal cancer results from mutations in components of the Wnt pathway that regulate beta-catenin levels. Dishevelled (Dvl or Dsh) signals downstream of Wnt receptors and stabilizes beta-catenin during cell proliferation and embryonic axis formation. Moreover, Dvl contributes to cytoskeletal reorganization during g...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature01056

    authors: Capelluto DG,Kutateladze TG,Habas R,Finkielstein CV,He X,Overduin M

    更新日期:2002-10-17 00:00:00

  • The projected timing of climate departure from recent variability.

    abstract::Ecological and societal disruptions by modern climate change are critically determined by the time frame over which climates shift beyond historical analogues. Here we present a new index of the year when the projected mean climate of a given location moves to a state continuously outside the bounds of historical vari...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature12540

    authors: Mora C,Frazier AG,Longman RJ,Dacks RS,Walton MM,Tong EJ,Sanchez JJ,Kaiser LR,Stender YO,Anderson JM,Ambrosino CM,Fernandez-Silva I,Giuseffi LM,Giambelluca TW

    更新日期:2013-10-10 00:00:00

  • Genes that mediate breast cancer metastasis to lung.

    abstract::By means of in vivo selection, transcriptomic analysis, functional verification and clinical validation, here we identify a set of genes that marks and mediates breast cancer metastasis to the lungs. Some of these genes serve dual functions, providing growth advantages both in the primary tumour and in the lung microe...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature03799

    authors: Minn AJ,Gupta GP,Siegel PM,Bos PD,Shu W,Giri DD,Viale A,Olshen AB,Gerald WL,Massagué J

    更新日期:2005-07-28 00:00:00

  • Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.

    abstract::Alternative splicing of pre-messenger RNAs diversifies gene products in eukaryotes and is guided by factors that enable spliceosomes to recognize particular splice sites. Here we report that alternative splicing of Saccharomyces cerevisiae SRC1 pre-mRNA is promoted by the conserved ubiquitin-like protein Hub1. Structu...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature10143

    authors: Mishra SK,Ammon T,Popowicz GM,Krajewski M,Nagel RJ,Ares M Jr,Holak TA,Jentsch S

    更新日期:2011-05-25 00:00:00

  • Global warming and climate forcing by recent albedo changes on Mars.

    abstract::For hundreds of years, scientists have tracked the changing appearance of Mars, first by hand drawings and later by photographs. Because of this historical record, many classical albedo patterns have long been known to shift in appearance over time. Decadal variations of the martian surface albedo are generally attrib...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature05718

    authors: Fenton LK,Geissler PE,Haberle RM

    更新日期:2007-04-05 00:00:00

  • Subtractive and divisive adaptation in the human visual system.

    abstract::Sensory systems can adapt to the conditions imposed on them. In the visual system, adapting to a pattern increases the threshold of the ability to see that pattern, and reduces the perceived contrast of the pattern above threshold. Most neurons of the striate cortex reduce their responsiveness after being stimulated f...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/355248a0

    authors: Snowden RJ,Hammett ST

    更新日期:1992-01-16 00:00:00

  • The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

    abstract::Ferroptosis is a form of regulated cell death that is caused by the iron-dependent peroxidation of lipids1,2. The glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis by converting lipid hydroperoxides into non-toxic lipid alcohols3,4. Ferroptosis has previously been implica...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/s41586-019-1705-2

    authors: Bersuker K,Hendricks JM,Li Z,Magtanong L,Ford B,Tang PH,Roberts MA,Tong B,Maimone TJ,Zoncu R,Bassik MC,Nomura DK,Dixon SJ,Olzmann JA

    更新日期:2019-11-01 00:00:00

  • Circulating human pituitary pro-gamma-melanotropin enhances the adrenal response to ACTH.

    abstract::The amino-terminal region of the common corticotropin/beta-lipotrophin (beta-LPH) precursor has been identified in the AtT-20 mouse tumor cells as a glycopeptide with an apparent molecular weight of 16,000 (the '16K fragment'). A third melanotropin core sequence or gamma-MSH similar to that found in ACTH and beta-LPH ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/291156a0

    authors: Al-Dujaili EA,Hope J,Estivariz FE,Lowry PJ,Edwards CR

    更新日期:1981-05-14 00:00:00

  • Loss-free and active optical negative-index metamaterials.

    abstract::The recently emerged fields of metamaterials and transformation optics promise a family of exciting applications such as invisibility, optical imaging with deeply subwavelength resolution and nanophotonics with the potential for much faster information processing. The possibility of creating optical negative-index met...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature09278

    authors: Xiao S,Drachev VP,Kildishev AV,Ni X,Chettiar UK,Yuan HK,Shalaev VM

    更新日期:2010-08-05 00:00:00

  • Fast heating of ultrahigh-density plasma as a step towards laser fusion ignition.

    abstract::Modern high-power lasers can generate extreme states of matter that are relevant to astrophysics, equation-of-state studies and fusion energy research. Laser-driven implosions of spherical polymer shells have, for example, achieved an increase in density of 1,000 times relative to the solid state. These densities are ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35090525

    authors: Kodama R,Norreys PA,Mima K,Dangor AE,Evans RG,Fujita H,Kitagawa Y,Krushelnick K,Miyakoshi T,Miyanaga N,Norimatsu T,Rose SJ,Shozaki T,Shigemori K,Sunahara A,Tampo M,Tanaka KA,Toyama Y,Yamanaka T,Zepf M

    更新日期:2001-08-23 00:00:00

  • Worries about infectious cancer.

    abstract::The recent discovery that the human T-cell lymphoma leukemia virus (HTLV) may be the agent of transmission of T-cell lymphoid malignancies raises ethical questions for blood transfusion services. The effort to avoid use of contaminated blood is dependent to a large extent on the willingness and ability of donors to g...

    journal_title:Nature

    pub_type: 新闻

    doi:10.1038/302567a0

    authors:

    更新日期:1983-04-14 00:00:00

  • An alternative approach to establishing trade-offs among greenhouse gases.

    abstract::The Kyoto Protocol permits countries to meet part of their emission reduction obligations by cutting back on gases other than CO2 (ref. 1). This approach requires a definition of trade-offs among the radiatively active gases. The Intergovernmental Panel on Climate Change has suggested global warming potentials for thi...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35070541

    authors: Manne AS,Richels RG

    更新日期:2001-04-05 00:00:00

  • Increased CO2 uncouples growth from isoprene emission in an agriforest ecosystem.

    abstract::The emission of isoprene from the leaves of forest trees is a fundamental component of biosphere-atmosphere interactions, controlling many aspects of photochemistry in the lower atmosphere. As almost all commercial agriforest species emit high levels of isoprene, proliferation of agriforest plantations has significant...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature01312

    authors: Rosenstiel TN,Potosnak MJ,Griffin KL,Fall R,Monson RK

    更新日期:2003-01-16 00:00:00

  • Co-localization of corticotropin-releasing factor and vasopressin in median eminence neurosecretory vesicles.

    abstract::Vasopressin (VP) potentiates the effect of corticotropin-releasing factor (CRF) on the secretion of adrenocorticotropic hormone (ACTH) from anterior pituitary cells in vitro, and both CRF and VP have been found in portal blood. These data support the hypothesis that VP acts synergistically with CRF to cause the secret...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/317248a0

    authors: Whitnall MH,Mezey E,Gainer H

    更新日期:1985-09-19 00:00:00

  • Density dependence explains tree species abundance and diversity in tropical forests.

    abstract::The recurrent patterns in the commonness and rarity of species in ecological communities--the relative species abundance--have puzzled ecologists for more than half a century. Here we show that the framework of the current neutral theory in ecology can easily be generalized to incorporate symmetric density dependence....

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature04030

    authors: Volkov I,Banavar JR,He F,Hubbell SP,Maritan A

    更新日期:2005-12-01 00:00:00

  • How thick is the lithosphere?

    abstract::A rapid decrease in shear velocity in the suboceanic mantle is used to infer the thickness of the lithosphere. It is proposed that new and highly precise group velocity data constrain the solutions and imply a thickness near 70 km. ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/226330a0

    authors: Kanamori H,Press F

    更新日期:1970-04-25 00:00:00

  • PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention.

    abstract::Haematopoietic stem cells (HSCs) must achieve a balance between quiescence and activation that fulfils immediate demands for haematopoiesis without compromising long-term stem cell maintenance, yet little is known about the molecular events governing this balance. Phosphatase and tensin homologue (PTEN) functions as a...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature04747

    authors: Zhang J,Grindley JC,Yin T,Jayasinghe S,He XC,Ross JT,Haug JS,Rupp D,Porter-Westpfahl KS,Wiedemann LM,Wu H,Li L

    更新日期:2006-05-25 00:00:00

  • Violation of the incompressibility of liquid by simple shear flow.

    abstract::In standard fluid dynamics, the density change associated with flow is often assumed to be negligible, implying that the fluid is incompressible. For example, this has been established for simple shear flows, where no pressure change is associated with flow: there is no volume deformation due to viscous stress and ine...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature05119

    authors: Furukawa A,Tanaka H

    更新日期:2006-09-28 00:00:00

  • Ultralow-threshold Raman laser using a spherical dielectric microcavity.

    abstract::The ability to confine and store optical energy in small volumes has implications in fields ranging from cavity quantum electrodynamics to photonics. Of all cavity geometries, micrometre-sized dielectric spherical resonators are the best in terms of their ability to store energy for long periods of time within small v...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/415621a

    authors: Spillane SM,Kippenberg TJ,Vahala KJ

    更新日期:2002-02-07 00:00:00

  • Contour from motion processing occurs in primary visual cortex.

    abstract::Relative motion is one of the most salient cues for segmentation of a visual scene into separate objects. This is illustrated by the vivid contours that are perceived when random dot patterns move in different directions. Once motion is halted in such displays the segmentation contours disappear. This makes random dot...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/363541a0

    authors: Lamme VA,van Dijk BW,Spekreijse H

    更新日期:1993-06-10 00:00:00

  • Europe's plan S could raise everyone else's publication paywall.

    abstract:: ...

    journal_title:Nature

    pub_type: 信件

    doi:10.1038/d41586-018-07152-z

    authors: Measey J

    更新日期:2018-10-01 00:00:00

  • Circulating mitochondrial DAMPs cause inflammatory responses to injury.

    abstract::Injury causes a systemic inflammatory response syndrome (SIRS) that is clinically much like sepsis. Microbial pathogen-associated molecular patterns (PAMPs) activate innate immunocytes through pattern recognition receptors. Similarly, cellular injury can release endogenous 'damage'-associated molecular patterns (DAMPs...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature08780

    authors: Zhang Q,Raoof M,Chen Y,Sumi Y,Sursal T,Junger W,Brohi K,Itagaki K,Hauser CJ

    更新日期:2010-03-04 00:00:00

  • Inflammation in atherosclerosis.

    abstract::Abundant data link hypercholesterolaemia to atherogenesis. However, only recently have we appreciated that inflammatory mechanisms couple dyslipidaemia to atheroma formation. Leukocyte recruitment and expression of pro-inflammatory cytokines characterize early atherogenesis, and malfunction of inflammatory mediators m...

    journal_title:Nature

    pub_type: 杂志文章,评审

    doi:10.1038/nature01323

    authors: Libby P

    更新日期:2002-12-19 00:00:00

  • Future sea-level rise from Greenland's main outlet glaciers in a warming climate.

    abstract::Over the past decade, ice loss from the Greenland Ice Sheet increased as a result of both increased surface melting and ice discharge to the ocean. The latter is controlled by the acceleration of ice flow and subsequent thinning of fast-flowing marine-terminating outlet glaciers. Quantifying the future dynamic contrib...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature12068

    authors: Nick FM,Vieli A,Andersen ML,Joughin I,Payne A,Edwards TL,Pattyn F,van de Wal RS

    更新日期:2013-05-09 00:00:00

  • Plus çà change.

    abstract::For the past couple of centuries the penchant for prediction has been prevalent at century turns. How much have evaluations of scientific discovery and predictions for future advancement changed since those of the science commentators at the end of the last century? ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/35011581

    authors: Heilbron JL,Bynum WF

    更新日期:1999-12-02 00:00:00

  • Detection and characterization of a folding intermediate in barnase by NMR.

    abstract::Protein engineering is being developed for mapping the energetics and pathway of protein folding. From kinetic studies on wild-type and mutant proteins, the sequence and energetics of formation of tertiary interactions of side chains can be mapped and the formation of secondary structure inferred. Here we cross-check ...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/346488a0

    authors: Bycroft M,Matouschek A,Kellis JT Jr,Serrano L,Fersht AR

    更新日期:1990-08-02 00:00:00

  • Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin.

    abstract::Insulin binding to its receptor leads to negatively cooperative interactions among the receptor sites. Studies with 29 insulin analogues (animal insulins and proinsulin, insulin-like growth factor and chemically modified insulins) which vary 1,000-fold in their affinity for the receptor and in their biological potency...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/273504a0

    authors: De Meyts P,Van Obberghen E,Roth J

    更新日期:1978-06-15 00:00:00

  • Trace element signature of subduction-zone fluids, melts and supercritical liquids at 120-180 km depth.

    abstract::Fluids and melts liberated from subducting oceanic crust recycle lithophile elements back into the mantle wedge, facilitate melting and ultimately lead to prolific subduction-zone arc volcanism. The nature and composition of the mobile phases generated in the subducting slab at high pressures have, however, remained l...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature03971

    authors: Kessel R,Schmidt MW,Ulmer P,Pettke T

    更新日期:2005-09-29 00:00:00

  • Genes required for GABA function in Caenorhabditis elegans.

    abstract::gamma-Aminobutyric acid (GABA) neurotransmission is widespread in vertebrate and invertebrate nervous systems. Here we use a genetic approach to identify molecules specific to GABA function. On the basis of the known in vivo roles of GABAergic neurons in controlling behaviour of the nematode Caenorhabditis elegans, we...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/364334a0

    authors: McIntire SL,Jorgensen E,Horvitz HR

    更新日期:1993-07-22 00:00:00

  • The genome of Cryptosporidium hominis.

    abstract::Cryptosporidium species cause acute gastroenteritis and diarrhoea worldwide. They are members of the Apicomplexa--protozoan pathogens that invade host cells by using a specialized apical complex and are usually transmitted by an invertebrate vector or intermediate host. In contrast to other Apicomplexans, Cryptosporid...

    journal_title:Nature

    pub_type: 杂志文章

    doi:10.1038/nature02977

    authors: Xu P,Widmer G,Wang Y,Ozaki LS,Alves JM,Serrano MG,Puiu D,Manque P,Akiyoshi D,Mackey AJ,Pearson WR,Dear PH,Bankier AT,Peterson DL,Abrahamsen MS,Kapur V,Tzipori S,Buck GA

    更新日期:2004-10-28 00:00:00