Abstract：
BACKGROUND:Cerebellar low-grade astrocytomas (CLGAs) of childhood are benign tumours and are usually curable by surgical resection alone or combined with adjuvant radiotherapy. OBJECTIVE:To undertake a retrospective study of our children with CLGA to determine the optimum schedule for surveillance imaging following initial surgery. In this report we describe the phenomenon of spontaneous regression of residual tumour and discuss its prognostic significance regarding future imaging. MATERIALS AND METHODS:A retrospective review was conducted of children treated for histologically proven CLGA at Great Ormond Street Hospital from 1988 to 1998. RESULTS:Of 83 children with CLGA identified, 13 (15.7%) had incomplete resections. Two children with large residual tumours associated with persistent symptoms underwent additional treatment. Eleven children were followed by surveillance imaging alone for a mean of 6.83 years (range 2-13.25 years). Spontaneous tumour regression was seen in 5 (45.5%) of the 11 children. There were no differences in age, gender, symptomatology, histological grade or Ki-67 fractions between those with spontaneous tumour regression and those with progression. There was a non-significant trend that larger volume residual tumours progressed. CONCLUSIONS:Residual tumour followed by surveillance imaging may either regress or progress. For children with residual disease we recommend surveillance imaging every 6 months for the first 2 years, every year for years 3, 4 and 5, then every second year if residual tumour is still present 5 years after initial surgery. This would detect not only progressive or recurrent disease, but also spontaneous regression which can occur later than disease progression.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Gunny RS,Hayward RD,Phipps KP,Harding BN,Saunders DEdoi
10.1007/s00247-005-1546-zkeywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
1086-91issue
11eissn
0301-0449issn
1432-1998journal_volume
35pub_type
杂志文章abstract：BACKGROUND:Fluoroscopy is an important, sometimes vital radiological procedure in paediatric patients with high variability in frequency and technique. OBJECTIVE:To obtain data on paediatric fluoroscopy practice in Europe using a simple questionnaire mailed to 191 children's hospitals. RESULTS:Eighty-eight radiology ...
journal_title：Pediatric radiology
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更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Knowledge of ovarian volume is important for diagnostic evaluations; however, normal ovarian volume studies on children and adolescents are lacking. OBJECTIVE:This study aimed to analyze age-specific ovarian volume and identify the diverse factors that contribute to ovarian diagnoses. MATERIALS AND METHODS...
journal_title：Pediatric radiology
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abstract：:Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vit...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-012-2532-x
更新日期：2013-01-01 00:00:00
abstract：:The approach to breast masses in children differs from that in adults in many ways, including the differential diagnostic considerations, imaging algorithm and appropriateness of biopsy as a means of further characterization. Most pediatric breast masses are benign, either related to breast development or benign neopl...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-015-3402-0
更新日期：2015-10-01 00:00:00
abstract：:Magnetic resonance imaging has been used to evaluate 10 children with lymphomas and was able to identify disease in all 10 cases and monitor response to therapy in all three patients with follow-up studies. It could not distinguish between the different histological types of lymphoma. The image intensity of a diseased...
journal_title：Pediatric radiology
pub_type： 杂志文章
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journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-004-1228-2
更新日期：2004-10-01 00:00:00
abstract：:We performed 25 percutaneous fine needle biopsies (PFNB) on pediatric patients during a 3-year period. Of 17 patients with proven malignancies, PFNB was true positive in 16 and false negative in one. In nine patients with benign or inflammatory disorders, there were three true positives and six false negatives. There ...
journal_title：Pediatric radiology
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doi：10.1007/BF02388363
更新日期：1985-01-01 00:00:00
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journal_title：Pediatric radiology
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更新日期：2021-01-05 00:00:00
abstract：BACKGROUND:We have previously shown that urinary bladder volume index (BVI = length x width x depth of bladder) and bladder volume wall thickness index (BVWI = BVI at full bladder/average bladder wall thickness) are useful indicators of bladder dysfunction in children with enuresis and urinary tract infection. These in...
journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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journal_title：Pediatric radiology
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更新日期：1993-01-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章,评审
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更新日期：2006-10-01 00:00:00
abstract：:Hemangiopericytoma (HP) is a rare vascular tumor that usually occurs in adults, but 10% occur in children. Tumors occurring in the first year of life are even more rare and are referred to as infantile hemangiopericytoma. In this article, we report the imaging, operative, and pathological findings in a patient with an...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050738
更新日期：2000-04-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/BF01372099
更新日期：1996-01-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章
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更新日期：1981-02-01 00:00:00
abstract：BACKGROUND:The effects and potential hazards of brain magnetic resonance imaging (MRI) at 3 T in newborns are debated. OBJECTIVE:Assess the impact of 3-T MRI in newborns on body temperature and physiological parameters. MATERIAL AND METHODS:Forty-nine newborns, born preterm and at term, underwent 3-T brain MRI at ter...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-018-4105-0
更新日期：2018-07-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02012496
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:We prospectively surveyed patients with myelomeningocele who presented in our department over a 3-month period to determine the frequency of latex allergy in this population. MATERIALS AND METHODS:A questionnaire assessed history of allergy to latex and attitudes toward and use or avoidance of latex-containi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01377199
更新日期：1996-07-01 00:00:00
abstract：:The CT appearance of oropharyngeal tularemia in a 3 1/2 year-old boy is described. Tularemia should be considered in the differential diagnosis of massive adenotonsillar enlargement and extensive necrotic cervical adenopathy. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02075217
更新日期：1990-01-01 00:00:00
abstract：:Parameters of linear measurement were compared with actual brain volume to assess the significance of linear measurements as indices of atrophy in 31 neurologically normal children and 22 neurologically abnormal children. Brain volume was established by means of an image-analyzing system using contiguous CT scans. The...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02013822
更新日期：1993-01-01 00:00:00
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更新日期：2017-05-01 00:00:00
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更新日期：2019-05-01 00:00:00
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journal_title：Pediatric radiology
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更新日期：1998-02-01 00:00:00
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journal_title：Pediatric radiology
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doi：10.1007/BF02388164
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journal_title：Pediatric radiology
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doi：10.1007/s00247-007-0495-0
更新日期：2007-09-01 00:00:00
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journal_title：Pediatric radiology
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更新日期：2014-01-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-011-2131-2
更新日期：2011-11-01 00:00:00
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journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00988657
更新日期：1976-10-26 00:00:00
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