当前位置： SCI文献检索 > MOLECULAR IMAGING AND BIOLOGY期刊下所有文献 > Impact of 2-deoxy-2[F-18]fluoro-D-glucose Positron Emission Tomography on the management of patients with advanced melanoma.

Impact of 2-deoxy-2[F-18]fluoro-D-glucose Positron Emission Tomography on the management of patients with advanced melanoma.

Abstract：

OBJECTIVES:Accurate staging of patients with melanoma is vital to guide appropriate treatment. 2-Deoxy-2-[F-18]fluoro-D-glucose (FDG)-positron emission tomography (PET) has been reported to be a sensitive and specific technique for the staging of advanced melanoma, however, few studies provide information regarding its impact on patient management. METHODS:We retrospectively reviewed the FDG-PET scan results of 92 patients with melanoma who had 126 scans performed over a six-year period. These patients were seen at the specialist melanoma clinic at our Institution, and 84 patients (92%) had stage III or IV disease. FDG-PET scan results were correlated with computed tomography (CT) scans and other imaging when available, and with clinical follow-up of a minimum of three to six months. The impact of FDG-PET scans on patient management was also assessed. RESULTS:On a lesion-by-lesion analysis, FDG-PET had a sensitivity of 92%, a specificity of 88%, and an accuracy of 91%. FDG-PET correctly affected the clinical decision-making process in 40 of 126 patient studies (32%), particularly assisting in the selection of patients for surgery. CONCLUSION:FDG-PET has an important role in guiding the management of patients with advanced melanoma, particularly when surgery is contemplated.

journal_name

Mol Imaging Biol

journal_title

Molecular imaging and biology

authors

Harris MT,Berlangieri SU,Cebon JS,Davis ID,Scott AM

doi

10.1007/s11307-005-0002-7

keywords:

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

304-8

issue

4

eissn

1536-1632

issn

1860-2002

journal_volume

7

pub_type

杂志文章

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