Thymic carcinoma in children.

Abstract:

:Thymic epithelial neoplasms consist of thymomas, thymic carcinoids, and thymic carcinomas. Carcinomas are malignant tumors of the thymus characterized by obvious cytological anaplasia. They constitute only 4%-14% of thymic epithelial neoplams. Thymic carcinoma rarely occurs in children. Research in the English literature carried out for the present study revealed only 14 cases younger than 18 years-of-age. Here we have reported a 16-year old girl who presented with respiratory distress due to huge anterior mediastinal mass. Histological and immunohistochemical studies confirmed lymphoepithelioma-like thymic carcinoma. She received systemic chemotherapy and radiotherapy. However, she died within 15 months due to progressive disease.

journal_name

Pediatr Blood Cancer

journal_title

Pediatric blood & cancer

authors

Yaris N,Nas Y,Cobanoglu U,Yavuz MN

doi

10.1002/pbc.20468

keywords:

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

224-7

issue

2

eissn

1545-5009

issn

1545-5017

journal_volume

47

pub_type

杂志文章,评审
  • Antiphospholid antibody syndrome and Hb E/Beta thalassemia disease post-allogeneic stem cell transplantation.

    abstract::We report a 10-year-old male with Hb E/Beta thalassemia disease who developed chronic graft-versus-host disease (cGVHD) of antiphospholipid antibody syndrome after successful allogeneic stem cell transplantation (SCT). He exhibited a recurrent ischemic stroke on day 368 post-SCT while on cyclosporine A, azathioprine, ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.23020

    authors: Sirachainan N,Pakakasama S,Hongeng S,Chuansumrit A,Tuntiyatorn L,Vilaiyuk S

    更新日期:2011-07-15 00:00:00

  • The burden of childhood cancer in Mexico: Implications for low- and middle-income countries.

    abstract::In Mexico, childhood cancer incidence and mortality have increased in the last decade. Through government actions since 2005, the Popular Medical Insurance (PMI) program for childhood cancer was created. The objective of PMI was to offer early cancer diagnosis, standardized treatment regimens, and numerous pediatric o...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审

    doi:10.1002/pbc.26366

    authors: Rivera-Luna R,Zapata-Tarres M,Shalkow-Klincovstein J,Velasco-Hidalgo L,Olaya-Vargas A,Finkelstein-Mizrahi N,Cárdenas-Cardós R,Aguilar-Ortiz MR

    更新日期:2017-06-01 00:00:00

  • Myeloid neoplasm with prominent eosinophilia and PDGFRA rearrangement treated with imatinib mesylate.

    abstract::The FIP1L1-PDGFRA fusion gene is the most frequent genetic aberration in myeloid neoplasms associated with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1. Affected patients in adult populations are very sensitive to imatinib therapy. Pediatric cases are rare and so far only one case of FIP1L1-PDGFRA positi...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.22655

    authors: Rathe M,Kristensen TK,Møller MB,Carlsen NL

    更新日期:2010-10-01 00:00:00

  • Long-term outcomes of children with extracutaneous juvenile xanthogranulomas in Japan.

    abstract:BACKGROUND:Juvenile xanthogranuloma (JXG) is the most common non-Langerhans cell histiocytosis in children. The mortality and morbidity of JXG with extracutaneous lesions remain unclear. METHODS:Data of patients aged < 18 years who were diagnosed with JXG between 2001 and 2010 were retrospectively collected through a ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28381

    authors: Maeda M,Morimoto A,Shioda Y,Asano T,Koga Y,Nakazawa Y,Kanegane H,Kudo K,Ohga S,Ishii E,Histiocytosis Study Group of the Japanese Society of Pediatric Hematology\/Oncology.

    更新日期:2020-07-01 00:00:00

  • Yield of Urinalysis Screening in Pediatric Cancer Survivors.

    abstract:BACKGROUND:The Children's Oncology Group (COG) publishes consensus guidelines with screening recommendations for early identification of treatment-related morbidities among childhood cancer survivors. We sought to estimate the yield of recommended yearly urinalysis screening for genitourinary complications as per Versi...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/pbc.25897

    authors: Ramirez MD,Mertens AC,Esiashvili N,Meacham LR,Wasilewski-Masker K

    更新日期:2016-05-01 00:00:00

  • A phase I trial of vorinostat and bortezomib in children with refractory or recurrent solid tumors: a Children's Oncology Group phase I consortium study (ADVL0916).

    abstract:BACKGROUND:A pediatric Phase I trial was performed to determine the maximum-tolerated dose, dose-limiting toxicities (DLTs), and pharmacokinetics (PK) of vorinostat and bortezomib, in patients with solid tumors. PROCEDURE:Oral vorinostat was administered on days 1-5 and 8-12 of a 21-day cycle (starting dose 180 mg/m(2...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.24271

    authors: Muscal JA,Thompson PA,Horton TM,Ingle AM,Ahern CH,McGovern RM,Reid JM,Ames MM,Espinoza-Delgado I,Weigel BJ,Blaney SM

    更新日期:2013-03-01 00:00:00

  • Protein biomarkers for incident deep venous thrombosis in critically ill adolescents: An exploratory study.

    abstract:BACKGROUND:There are no tests to identify critically ill children at high risk of deep venous thrombosis (DVT). In this exploratory study, we aimed to identify proteins that are associated with incident DVT in critically ill adolescents. PROCEDURE:Plasma samples were obtained from critically ill adolescents within 24 ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/pbc.28159

    authors: Tala JA,Polikoff LA,Pinto MG,Li S,Trakas E,Miksa M,Gertz S,Faustino EVS,THEIA Study Investigators.

    更新日期:2020-04-01 00:00:00

  • Contribution of fibrinolytic tests to the differential diagnosis of veno-occlusive disease complicating pediatric hematopoietic stem cell transplantation.

    abstract:BACKGROUND:Veno-occlusive disease (VOD) is a major complication following hematopoietic stem cell transplantation (HSCT). Its diagnosis is based on clinical criteria, which have a limited sensitivity. Increased plasminogen activator inhibitor-1 (PAI-1) levels have been suggested as a marker of VOD. We aimed to prospect...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.23213

    authors: Sartori MT,Cesaro S,Peruzzo M,Messina C,Saggiorato G,Calore E,Pillon M,Varotto S,Spiezia L,Cella G

    更新日期:2012-05-01 00:00:00

  • Impact of Whole-Body Radiation Dose on Response and Toxicity in Patients With Neuroblastoma After Therapy With 131 I-Metaiodobenzylguanidine (MIBG).

    abstract:BACKGROUND:(131) I-metaiodobenzylguanidine ((131) I-MIBG) is a targeted radiopharmaceutical for patients with neuroblastoma. Despite its tumor-specific uptake, the treatment with (131) I-MIBG results in whole-body radiation exposure. Our aim was to correlate whole-body radiation dose (WBD) from (131) I-MIBG with tumor ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25816

    authors: Trieu M,DuBois SG,Pon E,Nardo L,Hawkins RA,Marachelian A,Twist CJ,Park JR,Matthay KK

    更新日期:2016-03-01 00:00:00

  • Treatment of infantile choriocarcinoma of the liver.

    abstract::Primary choriocarcinoma of the liver is an extremely rare childhood malignancy frequently associated with clinical instability at initial presentation. It often mimics other benign and malignant childhood liver tumors. Prompt diagnosis and initiation of treatment are necessary to attain a successful outcome. We descri...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20623

    authors: Yoon JM,Burns RC,Malogolowkin MH,Mascarenhas L

    更新日期:2007-07-01 00:00:00

  • Features and outcome of neonatal leukemia in Japan: experience of the Japan infant leukemia study group.

    abstract:BACKGROUND:Neonatal leukemia characterized by early stem cell origin and extramedullary infiltration in the first 4 weeks of life is rare. We analyzed the features and outcome of neonatal leukemia in Japan to establish an appropriate treatment strategy for this rare disorder. PROCEDURE:Patients with infant leukemia re...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/pbc.20599

    authors: Ishii E,Oda M,Kinugawa N,Oda T,Takimoto T,Suzuki N,Kosaka Y,Ohara A,Ogawa A,Ishii M,Sakata N,Okamura T,Koike K,Kojima S,Horibe K,Mizutani S

    更新日期:2006-09-01 00:00:00

  • Anaphylactoid reaction to high-dose methotrexate and successful desensitization.

    abstract::Anaphylactic/anaphylactoid reaction to methotrexate (MTX) is uncommon. It may occur with the first dose (non-allergic reactions) or after a previous exposure to the drug (allergic or specific reactions). Desensitization has been shown effective in children with allergic-type reactions permitting the continuation of hi...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.22616

    authors: Oulego-Erroz I,Maneiro-Freire M,Bouzón-Alejandro M,Vázquez-Donsión M,Couselo JM

    更新日期:2010-09-01 00:00:00

  • Hyperbaric oxygen should not be used in the management of hemorrhagic cystitis in patients with Fanconi anemia.

    abstract::Hemorrhagic cystitis (HC) is a common complication after stem cell transplantation (SCT) that occurs more frequently in patients with Fanconi anemia (FA) because of hypersensitivity of their cells to the agents used in the preparation for SCT (chemo and radiation). Many HC cases respond to therapy with hyperhydration ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20692

    authors: Al-Seraihi A,Ayas M

    更新日期:2007-11-01 00:00:00

  • Clinical characteristics and outcomes of HIV-infected children diagnosed with Kaposi sarcoma in Malawi and Botswana.

    abstract:BACKGROUND:Kaposi sarcoma (KS) is the most common HIV-associated malignancy in sub-Saharan Africa. The presentation and outcomes of pediatric KS are not well understood. PROCEDURE:We performed a retrospective cohort analysis of 81 HIV-infected children with KS at the Baylor Children's Clinical Centres of Excellence in...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/pbc.24516

    authors: Cox CM,El-Mallawany NK,Kabue M,Kovarik C,Schutze GE,Kazembe PN,Mehta PS

    更新日期:2013-08-01 00:00:00

  • Transcranial Doppler screening in Nigerian children with sickle cell disease: A 10-year longitudinal study on the SPPIBA cohort.

    abstract:BACKGROUND:Primary stroke prevention programmes for children with sickle cell disease (SCD) have been shown to be feasible interventions in resource-poor countries. Different hydroxyurea (HU) regimens have been utilised in ameliorating the severity of SCD. OBJECTIVE:To determine the long-term outcomes of the stroke pr...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28906

    authors: Lagunju IA,Labaeka A,Ibeh JN,Orimadegun AE,Brown BJ,Sodeinde OO

    更新日期:2021-02-01 00:00:00

  • Medical and rehabilitation interventions in pediatric central nervous system radiation necrosis: A case report.

    abstract::Radiation necrosis is a potentially debilitating side effect of therapy necessary to treat pediatric central nervous system tumors. Clinical signs of cerebral radiation necrosis (CRN) are similar to symptoms of disease progression and require close monitoring. The case of an infant diagnosed with a malignant rhabdoid ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28705

    authors: L'Hotta AJ,Thomas KM,Milgrom SA,Hemenway MS,Levy JMM

    更新日期:2021-01-01 00:00:00

  • Prognostic impact of MYCN, DDX1, TrkA, and TrkC gene transcripts expression in neuroblastoma.

    abstract:BACKGROUND:The aims of this study were to define the mRNA expression profiles of MYCN, DDX1, TrkA, and TrkC in biopsy tumor samples from 64 Brazilian patients with neuroblastomas of different risk stages and to correlate altered expression with prognostic values. PROCEDURE:Patients were retrospectively classified into...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.22823

    authors: de Souza DR,Sanabani SS,de Souza AC,Filho Odone V,Epelman S,Bendit I

    更新日期:2011-05-01 00:00:00

  • Impact of melphalan dose during reduced-intensity conditioning on engraftment of cord blood transplantation for chronic Epstein-Barr virus-associated T or NK cell lymphoproliferative diseases.

    abstract::The rejection rate in cord blood transplants for chronic Epstein-Bar virus-associated T or natural killer cell lymphoproliferative diseases using our standard reduced-intensity conditioning "LPAM140 regimen," which includes fludarabine, melphalan (LPAM), etoposide, and antithymocyte globulin, has been high. To ensure ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.28536

    authors: Mayumi A,Sawada A,Sato M,Shimizu M,Ioi A,Higuchi K,Yasui M,Kawa K,Inoue M

    更新日期:2020-09-01 00:00:00

  • A new clinical score for disease activity in Langerhans cell histiocytosis.

    abstract:OBJECTIVE:To develop an objective tool for assessing disease activity in patients with Langerhans cell histiocytosis (LCH). METHOD:Scoring system was developed and applied to a database containing information on 612 patients. RESULTS:At diagnosis, the score distribution was highly asymmetrical: the score was between ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20160

    authors: Donadieu J,Piguet C,Bernard F,Barkaoui M,Ouache M,Bertrand Y,Ibrahim H,Emile JF,Hermine O,Tazi A,Genereau T,Thomas C

    更新日期:2004-12-01 00:00:00

  • PedsQL™ Multidimensional Fatigue Scale in sickle cell disease: feasibility, reliability, and validity.

    abstract:BACKGROUND:Sickle cell disease (SCD) is an inherited blood disorder characterized by a chronic hemolytic anemia that can contribute to fatigue and global cognitive impairment in patients. The study objective was to report on the feasibility, reliability, and validity of the PedsQL™ Multidimensional Fatigue Scale in SCD...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/pbc.24776

    authors: Panepinto JA,Torres S,Bendo CB,McCavit TL,Dinu B,Sherman-Bien S,Bemrich-Stolz C,Varni JW

    更新日期:2014-01-01 00:00:00

  • Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia.

    abstract:BACKGROUND:Extramedullary infiltration (EMI) is an occasional clinical symptom in childhood acute myelogenous leukemia (AML), but there is considerable controversy regarding the prognostic significance of EMI in AML. PROCEDURE:We evaluated the frequency and prognostic significance of EMI at diagnosis of AML in childre...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20824

    authors: Kobayashi R,Tawa A,Hanada R,Horibe K,Tsuchida M,Tsukimoto I,Japanese childhood AML cooperative study group.

    更新日期:2007-04-01 00:00:00

  • Hepatoblastoma in patients with molecularly proven familial adenomatous polyposis: Clinical characteristics and rationale for surveillance screening.

    abstract::Familial adenomatous polyposis (FAP) due to APC mutation is associated with an increased risk of hepatoblastoma. All cases of hepatoblastoma in patients with FAP reported in the literature were reviewed. One hundred and nine patients were identified. Thirty-five patients (of 49 with data) were diagnosed with hepatobla...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审

    doi:10.1002/pbc.27103

    authors: Trobaugh-Lotrario AD,López-Terrada D,Li P,Feusner JH

    更新日期:2018-08-01 00:00:00

  • Molecular characterization of a novel splice site mutation within the CYBB gene leading to X-linked chronic granulomatous disease.

    abstract::Chronic granulomatous disease (CGD) is a primary immunodeficiency that affects the oxidative mechanism of microbial killing of phagocytic cells. The defect is characterized by a lack or severely reduced superoxide anion (O2-) production by phagocytes. Seventy percent of CGD cases are X-linked (X-CGD) and they are caus...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.20204

    authors: Barese CN,Copelli SB,De Matteo E,Zandomeni R,Salgueiro F,Di Giovanni D,Heyworth P,Rivas EM

    更新日期:2005-04-01 00:00:00

  • Hydroxyurea lowers transcranial Doppler flow velocities in children with sickle cell anaemia in a Nigerian cohort.

    abstract:BACKGROUND:Sickle cell anaemia (SCA) is the leading genetic disorder in Nigeria. Elevated velocities ≥170 cm/sec occur in about a third of Nigerian children with SCA. Chronic blood transfusion for stroke prevention is faced with a myriad of challenges in our practice. OBJECTIVES:To evaluate the effectiveness of hydrox...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.25529

    authors: Lagunju I,Brown BJ,Sodeinde O

    更新日期:2015-09-01 00:00:00

  • Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group.

    abstract:BACKGROUND:Mutations in the DNMT3A, TET2, IDH1, and IDH2 genes carry prognostic significance and occur frequently in adult acute myeloid leukemia (AML). Leukemic mutations in all four genes have recently been implicated in aberrant DNA methylation, a hallmark of neoplasia. We previously reported that IDH1 mutations wer...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.23179

    authors: Ho PA,Kutny MA,Alonzo TA,Gerbing RB,Joaquin J,Raimondi SC,Gamis AS,Meshinchi S

    更新日期:2011-08-01 00:00:00

  • Non-activated protein C rescue treatment in Wilms tumour associated hepatic sinusoidal obstructive syndrome.

    abstract::Hepatic sinusoidal obstructive syndrome (HSOS) is a frequent complication in patients undergoing haematopoietic stem cell transplant (HSCT), and more rarely, in paediatric patients receiving conventional chemotherapy for solid tumours. Its diagnosis relies on a combination of clinical signs and symptoms such as hepato...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章

    doi:10.1002/pbc.24859

    authors: De Leonardis F,Koronica R,Bruno SD,Santoro N

    更新日期:2014-05-01 00:00:00

  • Incidence of acute kidney injury among pediatric hematology/oncology patients receiving vancomycin in combination with piperacillin/tazobactam or cefepime.

    abstract::There is mounting evidence that combination of antibiotic therapy with vancomycin and piperacillin/tazobactam (pip/tazo) is associated with acute kidney injury (AKI). To determine whether vancomycin plus pip/tazo is associated with higher rates of AKI compared to vancomycin plus cefepime among pediatric hematology/onc...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/pbc.27750

    authors: Quach HT,Esbenshade AJ,Zhao Z,Banerjee R

    更新日期:2019-07-01 00:00:00

  • Promoting adherence in adolescents and young adults with cancer to optimize outcomes: A developmentally oriented narrative review.

    abstract::Adherence is a critical consideration in ongoing efforts to improve outcomes among adolescents and young adults (AYAs) with cancer. In this narrative review, we embed existing conceptualizations of adherence within a developmental context to provide a novel vantage point from which to examine this important issue. App...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审

    doi:10.1002/pbc.28128

    authors: Vandermorris A,Sampson L,Korenblum C

    更新日期:2020-04-01 00:00:00

  • Metabolic syndrome in pediatric cancer survivors: a mechanistic review.

    abstract::Pediatric cancer survivors have increased risk of obesity, hypertension, dyslipidemia, and type 2 diabetes, leading to premature cardiovascular disease (CVD). Multiple tissues that are involved in glucose homeostasis and lipid metabolism are adversely affected by chemotherapy. This review highlights the relevant tissu...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审

    doi:10.1002/pbc.24703

    authors: Rosen GP,Nguyen HT,Shaibi GQ

    更新日期:2013-12-01 00:00:00

  • A proposal for an international retinoblastoma staging system.

    abstract:BACKGROUND:Although intra-retinal tumor has long been staged presurgically according to the Reese-Ellsworth (R-E) system, retinoblastoma differs from other pediatric neoplasms in never having had a widely accepted classification system that encompasses the entire spectrum of the disease. Comparisons among studies that ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/pbc.20606

    authors: Chantada G,Doz F,Antoneli CB,Grundy R,Clare Stannard FF,Dunkel IJ,Grabowski E,Leal-Leal C,Rodríguez-Galindo C,Schvartzman E,Popovic MB,Kremens B,Meadows AT,Zucker JM

    更新日期:2006-11-01 00:00:00