Deep vein thrombosis and pulmonary embolism reported in the Prescription Event Monitoring Study of Yasmin.

Abstract:

AIM:To evaluate cases of deep vein thrombosis (DVT) and pulmonary embolism (PE) reported in a prescription event monitoring study of Yasmin, an oral contraceptive. METHODS:Reports of DVT/PE and events suggestive of DVT/PE were followed up by questionnaire. RESULTS:Thirteen cases (DVT five; PE eight), each with possible risk factor(s), were identified in 15 645 females using Yasmin. Applying complete case analysis, the crude incidence rate was 13.7 cases per 10 000 woman-years (95% confidence interval 7.3, 23.4). CONCLUSIONS:Yasmin is associated with venous thromboembolism. An incidence rate has been calculated, but this may be subject to bias and should be interpreted with caution.

journal_name

Br J Clin Pharmacol

authors

Pearce HM,Layton D,Wilton LV,Shakir SA

doi

10.1111/j.1365-2125.2005.02373.x

keywords:

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

98-102

issue

1

eissn

0306-5251

issn

1365-2125

pii

BCP2373

journal_volume

60

pub_type

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