Is the occurrence of the empty follicle syndrome a predictor that a subsequent stimulated cycle will be an unfavourable one?

Abstract:

:Several hypotheses have been advanced to explain empty follicle syndrome (EFS) but it remains a controversial topic. This paper reports experience with three IVF cycles in which no oocytes were collected. In all cases, an additional IVF cycle was performed. The ovarian stimulation protocol, ultrasound and hormonal surveillance methods, human chorionic gonadotrophin timing and oocyte retrieval technique were similar in all patients. The assessment of additional cycles demonstrated a poor response in terms of oocyte quality, since the number of mature oocytes was low despite the high number of oocytes collected. Thus, the data suggest that in these patients, EFS should be considered as a borderline form of poor response to ovarian stimulation. If this is confirmed, EFS should be a recurrent event and an empty cycle could be a good predictor that a subsequent stimulated cycle will be an unfavourable.

journal_name

Reprod Biomed Online

authors

Lorusso F,Depalo R,Tsadilas S,Caradonna F,Di Gilio A,Capotorto MT,Vacca M,Nappi L,Selvaggi L

doi

10.1016/s1472-6483(10)61662-8

keywords:

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

571-4

issue

5

eissn

1472-6483

issn

1472-6491

pii

S1472-6483(10)61662-8

journal_volume

10

pub_type

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