Abstract：
:Despite the abundant experimental evidence for the irregular, multipeaked velocity profiles that often characterize rapid human limb movements, there is currently little agreement on how to interpret these phenomena. While in some studies these irregularities have been interpreted as reflecting a continuous control process, in others the irregularities are considered to be evidence for the existence of discrete movement primitives that are initiated by an intermittent controller. Here we introduce a novel "soft symmetry" method for analyzing irregular movements and decomposing them into their discrete movement primitives. We applied this method to analyze rapid pronation/supination wrist movements in monkeys during a one-dimensional tracking task. We showed that the properties of the extracted overlapping submovements (OSMs) were very similar to those of single, regular movements, despite the fact that the decomposition algorithm did not restrict the extracted submovements to a particular shape. In addition we showed that the movement primitives corrected preceding primitives and that the correction initiation time was highly variable, and thus could not be explained by the relatively fixed sensorimotor delay. These results argue against the interpretation of movement irregularities as reflecting a continuous control process and reinforce the hypothesis that movement irregularities result from an intermittent control mechanism. Demonstrating these phenomena in non-human primates will allow neurophysiological investigation of the neural mechanisms involved in these corrections.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Fishbach A,Roy SA,Bastianen C,Miller LE,Houk JCdoi
10.1007/s00221-005-2264-3keywords:
subject
Has Abstractpub_date
2005-08-01 00:00:00pages
442-57issue
4eissn
0014-4819issn
1432-1106journal_volume
164pub_type
杂志文章abstract：:The mesencephalic dopamine (DA) cell system was examined in mice homozygous and heterozygous for the weaver (wv) gene and in wild-type controls to estimate the extent of cell losses associated with the genetically determined central DA deficiency observed in weaver homozygotes. Animals of the three genotypes (+/+, wv/...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248351
更新日期：1988-01-01 00:00:00
abstract：:Several non-physiological stimuli (i.e. pharmacological or electrical stimuli) have been shown to induce Fos expression in striatal neurons. In this work, striatal Fos (i.e. Fos-like) expression was studied after physiological stimulation, i.e. motor activity (treadmill running at 36 m/min for 20 min). In rats killed ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005715
更新日期：1997-07-01 00:00:00
abstract：:The spatial separation of the eyes in animals with overlapping visual fields means that parts of a three dimensional object project to slightly disparate retinal points in each eye. This disparity, once interpreted by the brain, is thought to be a sufficient condition for stereoperception. In the present experiment, s...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239515
更新日期：1986-01-01 00:00:00
abstract：:This study investigated the importance of binocular vision to foot placement accuracy when stepping onto a floor-based target during gait initiation. Starting from stationary, participants placed alternate feet onto targets sequentially positioned along a straight travel path with the added constraint that the initial...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2910-x
更新日期：2012-01-01 00:00:00
abstract：:It is well established that neuronal transmission from the entorhinal cortex through the dentate gyrus via the perforant path is dependent on behavioral state. To further study the modulation of neuronal transmission by behavioral state we employed the paired-pulse technique to study interneuronally-mediated inhibitio...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00249612
更新日期：1989-01-01 00:00:00
abstract：:Pontine omnipause neurons (OPNs) have so far been considered as forming a homogeneous group of neurons whose tonic firing stops during the duration of saccades, when the head is immobilized. In cats, they pause for the total duration of gaze shifts, when the head is free to move. In the present study, carried out on a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050685
更新日期：1999-04-01 00:00:00
abstract：:Rhythmic auditory cues aim to modulate step times while walking. Their effect on the variability of minimum foot clearance, which is "normally" the most controlled gait parameter in normal overground walking, has not been studied, yet. We aim to analyse the effects of auditory cues on the variability of foot clearance...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4754-x
更新日期：2016-12-01 00:00:00
abstract：:Eye and head movements in the horizontal, frontal and sagittal planes were recorded in the rabbit with a newly developed technique using dual scleral search coils in a rotating magnetic field. The compensatory eye movements elicited by passive sinusoidal oscillation deteriorated for frequencies below 0.1 Hz in the hor...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236282
更新日期：1984-01-01 00:00:00
abstract：:In a recent study (Whitwell et al. in Exp Brain Res 185:111-119, 2008), we showed that the visuomotor system is "cognitively impenetrable" to the extent that explicit predictive knowledge of the availability of visual feedback on an upcoming trial fails to optimize grasping. The results suggested that the effects of t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1737-1
更新日期：2009-04-01 00:00:00
abstract：:A magnetic stimulus applied to the human scalp over the motor cortex causes a short latency contraction of contralateral limb muscles. This is presumed to result from the indirect excitation of corticospinal neurons with monosynaptic connections to motoneurons. The excitability of these cortical neurons can be estimat...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247369
更新日期：1989-01-01 00:00:00
abstract：:This paper reports on experiments in which the effect of disconnection of association fibres from Area 17/18 to the posterior suprasylvian cortex (PSSC) was investigated. In the control experiments, all neurons had large receptive fields in the central 5-10 degrees of the visual field without detailed retinotopy. In t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235537
更新日期：1983-01-01 00:00:00
abstract：:The purpose of this study was to investigate the role of cutaneous feedback in the agonist-antagonist co-activation mechanism during maximum voluntary force (MVF) production by the fingers. Seventeen healthy male subjects (age: 23.8 ± 1.0 years) were asked to press with maximal effort at their fingertips. Finger force...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3601-6
更新日期：2013-08-01 00:00:00
abstract：:Using near infrared spectroscopy and repetitive transcranial magnetic stimulation (rTMS), we studied interhemispheric interactions between bilateral motor and sensory cortices in humans. RTMS consisted of a triple-pulse burst (50 Hz) repeated every 200 m for 2 s (10 bursts, 30 pulses); one kind of theta burst TMS (TBS...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0884-5
更新日期：2007-07-01 00:00:00
abstract：:Sudden stretch of active muscle typically results in two characteristic electromyographic responses: the short latency M1 and the long latency M2. The M1 response originates from the monosynaptic Ia afferent reflex pathway. The M2 response is less well understood and is likely a compound response to different afferent...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1647-7
更新日期：2009-03-01 00:00:00
abstract：:Gait is recognized as a key item related to mental function. Anomalous gait in psychotic individuals has been described for the lower extremities, whereas irregularities for upper body dynamics are not described, explained or verified with unbiased methods. Reduced walking velocity and increased somatic tension define...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-012-3184-7
更新日期：2012-09-01 00:00:00
abstract：:The ventral part of the third visual cortical complex, the ventral posterior area (VP) or V3v, is located between the ventral half of visual areas V2 and V4. Because of its location and the physiological properties of its neurons, VP has been considered to be involved in the ventral stream visual areas. The ventral st...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1698-8
更新日期：2004-03-01 00:00:00
abstract：:In order to assess the effects of [K+]o on the passive membrane properties of neostriatal neurons, the cable properties of these cells were determined at two extracellular potassium concentrations (6.25 and 3.0 mM). The effect of tetraethylammonium (TEA) on cable properties was also studied at 6.25 [K+]o. At 6.25 mM [...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250260
更新日期：1988-01-01 00:00:00
abstract：:A recent study (Rossi et al. 2001) implied the absence of figure-ground based contextual modulation in macaque V1, in contrast to the study on which it was modelled (Zipser et al. 1996). We suggest that Rossi et al. may have underestimated the extent of modulation by considering only positive and not also negative mod...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1847-8
更新日期：2004-05-01 00:00:00
abstract：:Heparin affin regulatory peptide (HARP), also known as pleiotrophin or heparin-binding growth-associated molecule, is a developmentally regulated extracellular matrix protein that induces cell proliferation and promotes neurite outgrowth in vitro as well as pre- and postsynaptic developmental differentiation in vivo. ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000536
更新日期：2000-12-01 00:00:00
abstract：:The gain of the vestibulo-ocular reflex (VOR) of intact pigmented rats was adaptively modified by training protocols that created a visual-vestibular conflict. For training, head restrained animals were oscillated on a turntable in front of an optokinetic pattern projected onto a cylindrical wall. The optokinetic patt...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230530
更新日期：1991-01-01 00:00:00
abstract：:We employed binocular magnetic search coils to study the vestibulo-ocular reflex (VOR) and visually enhanced vestibulo-ocular reflex (VVOR) of 15 human subjects undergoing passive, whole-body rotations about a vertical (yaw) axis delivered as a series of pseudorandom transients and sinusoidal oscillations at frequenci...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005639
更新日期：1997-04-01 00:00:00
abstract：:A photographic technique was used to study the evolution of lateral head-tilt following hemilabyrinthectomy in adult cats. Animals were maintained post-operatively in normally lit conditions (LM cats), in total darkness (DM cats), or in stroboscopic light. In LM casts, the head tilt peaked at 45 degrees (with the lesi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235707
更新日期：1977-06-27 00:00:00
abstract：:There are important developmental changes occurring during infancy in visual cortical structures that underlie higher-order perceptual abilities. Using high-density electrophysiological recording techniques, the present study aimed to examine the development of visual mechanisms, during the first year of life, associa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0854-y
更新日期：2007-06-01 00:00:00
abstract：:Touches on one hand or forearm can affect tactile sensitivity at contralateral locations on the opposite side of the body. These interactions suggest an intimate connection between the two sides of the body. Here, we explore the effect of masking not across the body but through the body by measuring the effect of a ma...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3955-4
更新日期：2014-09-01 00:00:00
abstract：:Our perception of the vertical depends on allocentric information about the visual surrounds, egocentric information about the own body axis and gravicentric information about the pull of gravity. Previous work has documented that some individuals rely strongly on allocentric information, while others do not, and the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4526-z
更新日期：2016-04-01 00:00:00
abstract：:Morphometric changes have been studied at the mouse neuromuscular junction (NMJ) as a function of the frequency of stimulation. In vivo stimulation was made at either 10, 25, 50 or 100 Hz. No significant change in the area of NMJ profiles is observed after stimulation. This indicates that stimulation does not change t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237590
更新日期：1986-01-01 00:00:00
abstract：:The relationship between emotional or neutral declarative memory consolidation and sleep architecture was investigated. Thirty university students (21 females) viewed negative, neutral, or positive pictures and rated their valence and arousal in the evening. Participants performed a recognition test 1 h later and then...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3781-0
更新日期：2014-05-01 00:00:00
abstract：:An experiment was performed to characterise the movement kinematics and the electromyogram (EMG) during rhythmic voluntary flexion and extension of the wrist against different compliant (elastic-viscous-inertial) loads. Three levels of each type of load, and an unloaded condition, were employed. The movements were pac...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0946-z
更新日期：2002-02-01 00:00:00
abstract：:The study addresses three main questions: (1) Does the magnitude of the grasping force affect the prehension synergies, i.e., conjoint changes of finger forces and moments? (2) Do individual finger forces scale with the total grasping forces ('scale-invariance hypothesis')? (3) How specification of the grasping force ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1675-3
更新日期：2009-03-01 00:00:00
abstract：:Slow eye movements were observed while the monkey fixated on a subject-stationary, small target light in front of a moving optokinetic drum in an attempt to suppress optokinetic nystagmus (OKN). These slow eye movements of low amplitude were directed opposite to the moving optokinetic stimulus and, hence, were not ide...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248564
更新日期：1987-01-01 00:00:00
