The durability of virological success of tenofovir and didanosine dosed at either 400 or 250 mg once daily.

abstract：OBJECTIVES:We describe the management of a cohort of eight HIV-positive patients on antiretroviral medication with evidence of pancreatic insufficiency consisting of chronic diarrhoea and a low faecal elastase measurement. PATIENTS AND METHODS:Twenty-two patients with chronic diarrhoea for whom a faecal elastase measu...

journal_title：HIV medicine

authors： Price DA,Schmid ML,Ong EL,Adjukeiwicz KM,Peaston B,Snow MH

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Adipose dysregulation, dyslipidemia, and insulin resistance are hallmarks of HIV-related lipodystrophy. The precise mechanisms behind these disturbances are unknown. In HIV-infected patients, we previously demonstrated a strong relationship between lipodystrophy and levels of adiponectin, an adipose peptide ...

journal_title：HIV medicine

authors： Sankalé JL,Tong Q,Hadigan CM,Tan G,Grinspoon SK,Kanki PJ,Hotamisligil GS

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to describe Veterans Healthcare Administration (VHA) system-wide uptake of three HIV protease inhibitors: atazanavir, darunavir and tipranavir. METHODS:This retrospective cohort study evaluated VHA uptake of three target antiretrovirals and lopinavir/ritonavir in each complete 90-day...

journal_title：HIV medicine

authors： Belperio PS,Mole LA,Boothroyd DB,Backus LI

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:To study the impact of highly active antiretroviral therapy (HAART) on isotype switching and avidity maturation of HIV-1-specific immunoglobulin G (IgG) in patients with primary HIV-1 infection (PHI). METHODS:We studied the emergence and the evolution of anti-HIV IgG antibodies by quantitative immunoblottin...

journal_title：HIV medicine

authors： Adalid-Peralta L,Grangeot-Keros L,Rudent A,Ngo-Giang-Huong N,Krzysiek R,Goujard C,Deveau C,Le Gall M,Meyer L,Emilie D,Rouzioux C

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:To evaluate plasma levels of dehydroepiandrosterone sulphate (DHEAS) in a cohort of HIV-infected patients and to analyse factors associated with DHEAS levels. METHODS:We conducted a cross-sectional survey in the Nîmes University Hospital cohort of HIV-infected patients in south-eastern France. All HIV-infec...

journal_title：HIV medicine

authors： Mauboussin JM,Mahamat A,Peyrière H,Rouanet I,Fabbro-Peray P,Daures JP,Vincent D

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To establish the prevalence, severity and factors associated with the HIV lipodystrophy syndrome. METHODS:Cross-sectional study of lipodystrophy conducted in high HIV caseload primary care sites and HIV outpatient clinics. A subset of patients was examined using dual energy X-ray absorptiometry (DEXA) and si...

journal_title：HIV medicine

authors： Miller J,Carr A,Emery S,Law M,Mallal S,Baker D,Smith D,Kaldor J,Cooper DA

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe a UK-wide process to assess adherence to guidelines for the routine investigation and monitoring of HIV-positive adults aged ≥ 50 years and provide clinical services with individual feedback to support improvement in quality of care. METHODS:The British HIV Association (...

journal_title：HIV medicine

authors： Ekong N,Curtis H,Ong E,Sabin CA,Chadwick D,British HIV Association (BHIVA) Audit and Standards Sub-Committee.

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:Combination neonatal prophylaxis (CNP) is recommended in high-risk situations for the prevention of mother-to-child HIV transmission, although data on its safety are limited. The aim of the study was to identify whether neonatal prophylaxis (NP) type is associated with the risk of severe anaemia or neutropae...

journal_title：HIV medicine

authors： European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group in EuroCoord.

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:The World Health Organization (WHO) recommends screening HIV-infected people for cryptococcal antigens to identify cryptococcosis, a major cause of AIDS-related deaths. As the burden of cryptococcosis is unknown in South Africa's KwaZulu-Natal province, we assessed the cryptococcal antigenuria prevalence amo...

journal_title：HIV medicine

authors： Drain PK,Kleene JM,Coleman SM,Losina E,Katz JN,Giddy J,Ross D,Freedberg KA,Bassett IV

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To assess the incidence and consequences of adverse reactions among African HIV-positive pregnant women treated with fixed-dose combinations of a nevirapine-containing antiretroviral (ARV) triple therapy. METHODS:A retrospective analysis of the clinical files of 703 HIV-1-positive pregnant women treated with...

journal_title：HIV medicine

authors： Marazzi MC,Germano P,Liotta G,Guidotti G,Loureiro S,da Cruz Gomes A,Valls Blazquez MC,Narciso P,Perno CF,Mancinelli S,Palombi L

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:GB virus type C (GBV-C) viraemia is associated with a beneficial outcome in HIV-infected individuals in several though not all studies. GBV-C viraemia was examined in a matched case-control study of 133 HIV-infected pregnant women who transmitted HIV to their infants ('cases') and 266 non-transmitting contro...

journal_title：HIV medicine

authors： Handelsman E,Cheng I,Thompson B,Hershow R,Mofenson LM,Hollinger FB,Chen KT,Burchett SK,Klinzman D,Stapleton JT,Women and Infants Transmission Study Group (WITS).

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to compare the effects on lipids, body composition and renal function of once-daily ritonavir-boosted saquinavir (SQV/r) or atazanavir (ATV/r) in combination with tenofovir/emtricitabine (TDF/FTC) over 48 weeks. METHODS:An investigator-initiated, randomized, open-label, multinationa...

journal_title：HIV medicine

authors： Vrouenraets SM,Wit FW,Fernandez Garcia E,Moyle GJ,Jackson AG,Allavena C,Raffi F,Jayaweera DT,Mauss S,Katlama C,Fisher M,Slama L,Hardy WD,Dejesus E,van Eeden A,Reiss P,BASIC Study Group.

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Highly active antiretroviral therapy (HAART) has increased longevity. Currently, women comprise >50% of HIV-infected individuals worldwide. It is not known if there are differences between the sexes in the immunological and virological responses to HAART across the age strata. METHODS:Immunological reconsti...

journal_title：HIV medicine

authors： Patterson K,Napravnik S,Eron J,Keruly J,Moore R

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Despite adequate suppression of plasma HIV RNA, viral escape in cerebrospinal fluid (CSF) is widely reported. Rates of CSF HIV RNA escape vary in the literature. In persons living with HIV (PLWH) undergoing lumbar puncture examination for clinical reasons, we assessed rates of CSF HIV RNA escape. METHODS:Pe...

journal_title：HIV medicine

authors： Di Carlofelice M,Everitt A,Muir D,Winston A

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:A significant percentage of patients infected with HIV-1 experience only suboptimal CD4 cell recovery while treated with combination therapy (cART). It is still unclear whether viral properties such as cell tropism play a major role in this incomplete immune response. This study therefore intended to follow ...

journal_title：HIV medicine

authors： Bader J,Schöni-Affolter F,Böni J,Gorgievski-Hrisoho M,Martinetti G,Battegay M,Klimkait T,Swiss HIV Cohort Study.

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Despite the availability of HIV testing guidelines to facilitate prompt diagnosis, late HIV diagnosis remains high across Europe. The study synthesizes recent evidence on HIV testing strategies adopted in health care settings in the European Union/European Economic Area (EU/EEA). METHODS:Preferred Reporting...

journal_title：HIV medicine

authors： Desai S,Tavoschi L,Sullivan AK,Combs L,Raben D,Delpech V,Jakobsen SF,Amato-Gauci AJ,Croxford S

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:To investigate the concordance between any of the results of nine HIV-1 drug-resistance interpretation systems (ISs) and their ability to predict week 8 and week 24 virological responses to abacavir-containing combination therapy. PATIENTS AND METHODS:A total of 1306 HIV-infected patients with a viral load ...

journal_title：HIV medicine

authors： Cozzi-Lepri A,Standardization and Clinical Relevance of HIV Drug Resistance Testing Project for the Forum for Collaborative HIV Research.

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:With the prolonged survival time of AIDS patients, complications of various systems and organs of HIV infection are increasingly prominent. These diseases have become the major factors influencing the quality of life and prognosis of HIV-infected persons, and multidisciplinary cooperation treatment is urgent...

journal_title：HIV medicine

authors： Lin L,Li TS

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:There is increasing in vitro and in vivo evidence that reduced zidovudine (ZDV) susceptibility is generated by the selective pressure conferred by other nucleoside reverse transcriptase inhibitors (NRTIs). However, the degree to which this occurs in clinical practice remains unclear. We assessed phenotypic a...

journal_title：HIV medicine

authors： Gilleece Y,Torti C,Mandalia S,Gazzard BG,Pillay D,Pozniak AL

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:To determine whether mutations conferring drug resistance are detectable after zidovudine monotherapy (ZDVm) in pregnancy, using both standard genotyping and more sensitive cloning assays. METHODS:Post-delivery samples from women meeting the British HIV Association guidelines criteria for the use of ZDVm in...

journal_title：HIV medicine

authors： Read P,Costelloe S,Mullen J,O'Shea S,Lyons F,Hay P,Welch J,Larbalestier N,Taylor G,de Ruiter A

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to systematically review current studies reporting on clinical outcomes in people living with HIV (PLHIV) infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). METHODS:We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews a...

journal_title：HIV medicine

authors： Cooper TJ,Woodward BL,Alom S,Harky A

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to reconstruct the HIV epidemic in Australia for selected populations categorized by exposure route; namely, transmission among men who have sex with men (MSM), transmission among injecting drug users (IDUs), and transmission among heterosexual men and women in Australia. DESIGN:Sta...

journal_title：HIV medicine

authors： Wand H,Yan P,Wilson D,McDonald A,Middleton M,Kaldor J,Law M

更新日期：2010-07-01 00:00:00

abstract：:Kaposi's sarcoma (KS) is the most prevalent AIDS-associated tumour, occurring in 20-30% of HIV-1-infected individuals in the early 1980s. The introduction of highly active antiretroviral therapy (HAART) has dramatically reduced the incidence of the disease and might therefore support the concept of 'opportunistic mali...

journal_title：HIV medicine

authors： Hermans P

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:AIDS-related lymphoma (ARL) remains the main cause of AIDS-related deaths in the combined antiretroviral therapy (cART) era. Although most ARLs are associated with the Epstein-Barr virus (EBV), whether patients with high EBV burden are more at risk of developing ARL is unknown. This study investigated the re...

journal_title：HIV medicine

authors： Leruez-Ville M,Seng R,Morand P,Boufassa F,Boue F,Deveau C,Rouzioux C,Goujard C,Seigneurin JM,Meyer L

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Socio-economic factors and lifestyle are known to differ across geographies and populations, which may result in distinct risk profiles for cardiovascular disease (CVD). This study assessed carotid intima-media thickness (CIMT), a proxy for CVD, and its determinants in two groups of people living with HIV (P...

journal_title：HIV medicine

authors： Roozen G,Vos AG,Tempelman HA,Venter W,Grobbee DE,Scheuermaier K,Klipstein-Grobusch K

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Human leukocyte antigen (HLA)-B(*)5701 is strongly associated with developing a hypersensitivity reaction to abacavir (ABC) in White and Hispanic subjects. Across the UK, limited data exist on HLA-B(*)5701 prevalence in HIV-1-infected subjects. We determined HLA-B(*)5701 prevalence in the general HIV-1-infec...

journal_title：HIV medicine

authors： Orkin C,Sadiq ST,Rice L,Jackson F,UK EPI team.

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Few studies have explored the optimal dosing for efavirenz in individuals from China. We investigated plasma efavirenz concentrations and their association with efficacy and tolerance of efavirenz 600 mg daily in Chinese HIV-infected adults. METHODS:An analysis was performed using plasma samples from 455 pa...

journal_title：HIV medicine

authors： Guo F,Cheng X,Hsieh E,Du X,Fu Q,Peng W,Li Y,Song X,Routy JP,Li T

更新日期：2018-05-15 00:00:00

abstract：:One-half of the estimated 2.5 million people who now live with HIV in the World Health Organization (WHO) European Region are still diagnosed late. A central question is which clinical scenarios should trigger an HIV test recommendation in order to avoid late presentation. Drawing on the work of the HIV Indicator Dise...

journal_title：HIV medicine

authors： Lazarus JV,Hoekstra M,Raben D,Delpech V,Coenen T,Lundgren JD,HIV in Europe Initiative Steering Committee.

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, is a drug that is frequently included in highly active antiretroviral therapy for treatment of HIV infection. Decreased bioavailability and increased toxicity limit its use. We report a formulation of efavirenz-loaded lactoferrin nanoparticle...

journal_title：HIV medicine

authors： Kumar P,Lakshmi YS,Kondapi AK

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:The extent to which highly active antiretroviral therapy (HAART) affects human papillomavirus (HPV) acquisition and clearance in HIV-infected women is not well understood. We sought to describe high-risk HPV detection and clearance rates over time since HAART initiation, based on time-varying HIV viral load ...

journal_title：HIV medicine

authors： Kang M,Cu-Uvin S

更新日期：2012-07-01 00:00:00