In silico modelling of ADMET-a minireview of work from 2000 to 2004.

Abstract:

:This article represents a minireview of work published so far in the 21st century in the in silico ADMET field of research related to investigations in the areas of solubility, hERG and cytochrome P450 3A4. Various approaches including 2D- and 3D-QSARs and pharmacophore modelling are discussed. The pros and cons of the methods used and models derived are examined. More general remarks on model development and validation are also reported.

journal_name

SAR QSAR Environ Res

authors

Norinder U

doi

10.1080/10629360412331319835

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

1-11

issue

1-2

eissn

1062-936X

issn

1029-046X

journal_volume

16

pub_type

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