Physiology: postprandial cardiac hypertrophy in pythons.

Abstract:

:Oxygen consumption by carnivorous reptiles increases enormously after they have eaten a large meal in order to meet metabolic demands, and this places an extra load on the cardiovascular system. Here we show that there is an extraordinarily rapid 40% increase in ventricular muscle mass in Burmese pythons (Python molurus) a mere 48 hours after feeding, which results from increased gene expression of muscle-contractile proteins. As this fully reversible hypertrophy occurs naturally, it could provide a useful model for investigating the mechanisms that lead to cardiac growth in other animals.

journal_name

Nature

journal_title

Nature

authors

Andersen JB,Rourke BC,Caiozzo VJ,Bennett AF,Hicks JW

doi

10.1038/434037a

keywords:

subject

Has Abstract

pub_date

2005-03-03 00:00:00

pages

37-8

issue

7029

eissn

0028-0836

issn

1476-4687

pii

434037a

journal_volume

434

pub_type

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