Abstract:
:Jigrine a polypharmaceutical herbal hepatoprotective formulation containing aqueous extracts of 14 medicinal plants is used in Indian system of medicine (Unani). Jigrine was evaluated for its hepatoprotective activity against galactosamine induced hepatopathy in rats. Galactosamine induced hepatotoxicity resembles human viral hepatitis. Biochemical parameters like AST, ALT and urea in serum, TBARS and glutathione in liver and whole blood glutathione were estimated to assess liver function. DPPH-free radical scavenging activity of jigrine was also evaluated. Biochemical data exhibited significant hepatoprotective activity of jigrine against galactosamine. Silymarin used as reference standard also exhibited significant hepatoprotective activity against galactosamine. The biochemical observations were supplemented with histopathological examination of rat liver sections.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Najmi AK,Pillai KK,Pal SN,Aqil Mdoi
10.1016/j.jep.2004.12.016keywords:
subject
Has Abstractpub_date
2005-03-21 00:00:00pages
521-5issue
3eissn
0378-8741issn
1872-7573pii
S0378-8741(05)00020-6journal_volume
97pub_type
杂志文章abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Withania somnifera root extract (Ws)/Ashwagandha/Indian ginseng is a traditional herbal medicine, used over 4000 years in India, shown to have effect on neural growth and locomotor function. Although catecholamines and oxidative stress resulting in neurodegeneration and locomotor disorder...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2009.08.003
更新日期:2009-09-25 00:00:00
abstract::A total of 418 healers have been interviewed in Guinea, a coastal country of West Africa, ranging between 7 degrees 30 and 12 degrees 30 of northern latitude and 8 degrees and 15 degrees of western longitude. Plant species used by the local inhabitants to treat infectious diseases were identified using ethnobotanical,...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.07.009
更新日期:2007-10-08 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ginseng, the roots and rhizomes of Panax ginseng C.A. Mey. (Araliaceae), is used as a tonic herb for thousands of years in Asian countries. Saponins are recognized as its major active ingredients and reportedly can ease disorders caused by various adverse stimuli. Nevertheless, it is uncl...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.04.028
更新日期:2016-07-21 00:00:00
abstract:AIM OF THE STUDY:Cajanus cajan Linn. (Leguminosae) is a nontoxic edible herb, widely used in Indian folk medicine for the prevention of various liver disorders. In the present study we have demonstrated that methanol-aqueous fraction (MAF2) of Cajanus cajan leaf extract could prevent the chronically treated alcohol ind...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2008.05.010
更新日期:2008-08-13 00:00:00
abstract::The antimicrobial activity of the methanolic extract from the stem bark of Irvingia gabonensis (IGM), fractions and compounds isolated from IGM [3-friedelanone (1), betulinic acid (2), oleanolic acid (3), 3,3',4'-tri-O-methylellagic acid (4), 3,4-di-O-methylellagic acid (5) and hardwickiic acid (6)] was evaluated agai...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2007.07.025
更新日期:2007-10-08 00:00:00
abstract::Trigonella foenum-graecum (Fenugreek) (Leguminosae) is employed as a herbal medicine. Its seeds are known for their carminative, tonic and antidiabetic effects. A curative dose of Trigonella foenum-graecum also produces antiulcer action. In this study we have investigated the hypoglycaemic activities of the aqueous ex...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(01)00186-6
更新日期:2001-05-01 00:00:00
abstract::The effects of daily administration of Withania somnifera root extract (1.4 g/kg body wt.) and Bauhinia purpurea bark extract (2.5 mg/kg body wt.) for 20 days on thyroid function in female mice were investigated. While serum triiodothyronine (T3) and thyroxine (T4) concentrations were increased significantly by Bauhin...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(99)00018-5
更新日期:1999-11-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Medicinal plants from the Caatinga, a Brazilian xeric shrubland, are used in folk medicine to treat infections. These ethnopharmacological data can contribute to obtaining new antimicrobial/antibiofilm extracts and natural product prototypes for the development of new drugs. The aim of th...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2011.05.030
更新日期:2011-09-01 00:00:00
abstract::The effect of an aqueous extract of Moringa oleifera roots was studied histologically on the genital tract of ovariectomized rats in the presence and absence of estradiol dipropionate and progesterone. Administration of the extract itself stimulated the uterine histoarchitecture as revealed by increases in the height ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/0378-8741(89)90031-7
更新日期:1989-05-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Substantially, plants produce chemicals such as primary and secondary metabolites, which have significant applications in modern therapy. Indigenous people mostly rely on traditional medicines derived from medicinal plants. These plants have the capacity to absorb a variety of toxic eleme...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2016.05.011
更新日期:2016-07-21 00:00:00
abstract::The botanical remedies reported in Heyne's De Nuttige Planten van Nederlandsch-Indië (Volumes 1--IV, 1913--1922) have been screened out of economic botanical context, translated into English and summarized as a table of names, therapeutic indications, plant parts, and available details of preparation and use. ...
journal_title:Journal of ethnopharmacology
pub_type: 历史文章,杂志文章
doi:10.1016/0378-8741(83)90016-8
更新日期:1983-03-01 00:00:00
abstract::Poisonous plants and animals are widespread in nature and have been used for a great variety of purposes. Brief discussions of a number of examples: aconite, ergot, Euphorbiaceae/Thymelaeaceae, curare, cardiac glycosides, triterpenoid saponins and animal toxins, make the point that, in addition to allowing their use a...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/0378-8741(91)90105-m
更新日期:1991-04-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Origanum majorana L. (Lamiaceae) was usually used in Moroccan folk medicine to treat infantile colic and abdominal discomfort. MATERIALS AND METHODS:The essential oil from the aerial part of the dry Origanum majorana L. (EOOM) was obtained through hydro distillation and analyzed by gas c...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2018.08.036
更新日期:2019-01-10 00:00:00
abstract::The present study was undertaken to investigate the antinociceptive and anti-inflammatory activities of the leaf and twig extracts of Dorstenia barteri (Moraceae) in mice. Both the leaf and twig extracts of Dorstenia barteri at 50, 100 and 200 mg/kg showed significant (P < 0.05-0.01) antinociceptive activities in chem...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2004.05.022
更新日期:2004-11-01 00:00:00
abstract:AIM OF THE STUDY:Tanshinone IIA (T), salvianolic acid B (S) and ginsenoside Rb1 (G) are the three major active ingredients of Compound Danshen Formula (CDF) for its protective effects on myocardial ischemia (MI). In this study, we aimed to investigate therapeutic and synergistic effects of TSG (combination of T, S and ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2010.11.048
更新日期:2011-03-08 00:00:00
abstract:AIM OF THE STUDY:The purpose of this study is to isolate the pure compounds from the extracts of Cordyceps militaris obtained through solid-state cultivation process, and evaluate their anti-inflammatory and anticancer properties. MATERIALS AND METHODS:Silica gel column chromatographic purification of Cordyceps milita...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2010.07.020
更新日期:2010-09-15 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Biophytum umbraculum Welw. (Oxalidaceae) is a highly valued African medicinal plant used for treatment of cerebral malaria, a critical complication of falciparum malaria. AIM OF THE STUDY:To provide additional information about traditional use of B. umbraculum and to test plant extracts ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.05.058
更新日期:2016-08-22 00:00:00
abstract:BACKGROUND AND AIM:Chronic glomerulonephritis (CGN) is a primary glomerular disease that is related to immune-mediated inflammatory diseases. Qi Teng Xiao Zhuo granules have been proposed as a prescription of traditional Chinese medicine for treatment of CGN, but the comprehensive molecular mechanism underlying this th...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.08.011
更新日期:2016-12-04 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Leea macrophylla Roxb. ex Hornem. (Leeaceae) commonly known as Hastikarnapalasa is mainly distributed throughout the tropical parts of India. Traditionally, the plant is found to be effective against guinea worm, ringworm and is applied to sores and wounds. AIM OF THE STUDY:The present s...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.06.034
更新日期:2016-09-15 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Pistachio hull has traditionally been used to treat peptic ulcer, hemorrhoids, oral and cutaneous wounds. AIM OF THE STUDY:On the basis of its traditional uses and previous pharmacological reports, a bioassay guided fractionation procedures on pistachio (Pistacia vera L.) hulls was perfo...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2019.112335
更新日期:2020-02-10 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Huperzia saururus (Lam.) Trevis. has an extensive ethnopharmacological use, mainly because of its aphrodisiac properties. The species is consumed as decoctions or infusions in traditional medicine. The purpose of the present research was to determine if Huperzia saururus is able to increa...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2014.09.016
更新日期:2014-11-18 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Polygonum cuspidatum Sieb. et Zucc. (Polygonum cuspidatum), also known as Reynoutria japonica Houtt and Huzhang in China, is a traditional and popular Chinese medicinal herb. Polygonum cuspidatum with a wide spectrum of pharmacological effects has been used for treatment of inflammation, ...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,评审
doi:10.1016/j.jep.2013.05.007
更新日期:2013-07-30 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In Persian ethnomedicine several herbal remedies and functional foods have been used to treat migraine headache which are mostly summarized in Qarabadin-e-kabir (Aghili-Shirazi MH, 1773). One of them is Citron syrup (Sharbat-e-Balang) containing edible Citrus medica L. fruit juice and sug...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jep.2015.12.040
更新日期:2016-02-17 00:00:00
abstract::Folk medicine practitioners in Perú employ plant preparations as wound-healing agents on superficial and internal wounds (gastric ulcers). The results of a scientific evaluation of the wound-healing activity of nine plants found in the Amazon jungle near Iquitos and in the Andes mountains is presented. The species stu...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(96)01500-0
更新日期:1997-02-01 00:00:00
abstract::Hydroethanol (HE) and methanol (ME) extracts obtained from the leaves of Passiflora actinia Hooker were evaluated for behavioral effects in mice. Single-dose oral administration of HE (300 and 600 mg/kg) or ME (100 and 300 mg/kg) resulted in anxiolytic-like effects in the elevated plus-maze. The anxiolytic-like effect...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2006.11.021
更新日期:2007-05-04 00:00:00
abstract::Methanol, ethylacetate and aqueous extracts of Ruellia praetermissa initiated spontaneous contractions in the quiescent and increased contraction on the electrically stimulated ileal strip at a concentration of 30 microg/ml. The extracts produced concentration-related contractions both in amplitude and tone up till 75...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/s0378-8741(00)00204-x
更新日期:2000-09-01 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Melicope lunu-ankenda leaves are used to treat diabetes in folklore medicinal practices in India and Malaysia. Here we report the isolation of an O-prenylated flavonoid (3,5,4'-trihydroxy-8,3'-dimethoxy-7-(3-methylbut-2-enoxy)flavone; OPF) from the leaves of M. lunu-ankenda and its antidi...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2015.03.060
更新日期:2015-06-20 00:00:00
abstract::The aim of this study was to investigate the immunomodulatory effects of the volatile oil of ginger (Zingiber officinale Roscoe) in vitro and in vivo in mice. In vitro, the volatile oil of ginger (0.001-10 ng/mL) significantly inhibited T lymphocyte proliferation (P < 0.01), decreased the number of the total T lymphoc...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2005.10.022
更新日期:2006-04-21 00:00:00
abstract:BACKGROUND:Medicinal plant traditional knowledge is one of the most widely known traditional ecosystem services, as it provides primary healthcare, contributes to subsistence livelihoods, and for its potential value as a source of novel pharmaceuticals. People living in close contact with their surroundings for many ge...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2012.03.017
更新日期:2012-05-07 00:00:00
abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The ethnic Chinese Yao medicine Baizuan, which are the leaves of Schisandra viridis A. C. Smith, is traditionally used, in combination with other herbs, to soften hard lumps and dispel nodes in the treatment of cancer, however, this property has not been well studied with a clear indicati...
journal_title:Journal of ethnopharmacology
pub_type: 杂志文章
doi:10.1016/j.jep.2016.09.016
更新日期:2016-12-24 00:00:00