Abstract：
:Piecemeal degranulation (PMD) has been recognized in two cases of human pheochromocytoma from the adrenal medulla, which were studied by transmission electron microscopy. Tumour pheochromocytes presented a highly characteristic cytoplasmic admixture of normal resting granules, swollen granules with eroded matrices and enlarged empty containers. Chromaffin granules that appeared to be normal and altered granules maintained their individual structure, and did not fuse with each other or with the plasma membrane. In accordance with the currently accepted model for granule discharge during PMD, electron-dense or clear vesicles 30-150 nm in diameter were seen either attached to the surface of chromaffin granules and the plasma membrane or free in the cytosol. This is the first description of PMD in human adrenal chromaffin cells and, in addition, is the first report of PMD in tumour secretory cells. These findings add further to the concept that PMD may have a broader spectrum of expression than hitherto recognized.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Crivellato E,Finato N,Ribatti D,Beltrami CAdoi
10.1111/j.0021-8782.2005.00365.xkeywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
47-53issue
1eissn
0021-8782issn
1469-7580pii
JOA365journal_volume
206pub_type
杂志文章abstract：:Previous work, almost four decades ago, showed that hydrocortisone (HC) treatment reduces the number of skeletogenic condensations that give rise to the scleral ossicles in the chicken eye. The scleral ossicles are a ring of overlapping intramembranous bones, the sclerotic ring, and are present in most reptiles, inclu...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12744
更新日期：2018-02-01 00:00:00
abstract：:Maternal intraperitoneal administration of 1 mg/kg 5-azacytidine to pregnant S1c:ICR mice on gestational Day 7.5 resulted in a high incidence of exencephalic offspring. Histological examination of untreated 7.5 days mouse embryos revealed that the head folds were formed in the anterior halves of the embryos, whereas t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:This paper describes a qualitative and quantitative investigation into the location of the motoneurons innervating the extra-ocular muscles of the rat. Injections of horseradish peroxidase, bisbenzimide, propidium iodide and DAPI-primuline were made either in one or simultaneously in two muscles. Unlike those of the c...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：:The proximal stump of the optic nerve was examined by electron microscopy from 1 d to 8 wk (dpo/wpo) after intraorbital transection. At 1 dpo a layer of axonal, cytoplasmic and myelin debris approximately 15 microns thick was present at the cut end. A zone approximately 25 microns thick of abnormal and partly degenera...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:There is a limited understanding of the normal function of the pterygoïdeus proprius muscle and the role that this muscle may have in temporomandibular disorders. Despite a well-described anatomical in-vitro approach to this muscle, there are still difficulties in investigating the fossa pterygopalatina. This study re...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2010.01308.x
更新日期：2010-12-01 00:00:00
abstract：:The effects of varying periods of general protein-calorie undernutrition during early life on Purkinje cells in the cerebellum of the rat were examined. In Experiment 1, animals were undernourished from d 18 of gestation until either d 30 or d 60 of postnatal age, followed in some cases by a period of nutritional reha...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:This review describes the progress made in preparing Cochrane systematic reviews of randomized controlled trials for Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy (MMN) and the demyelinating neuropathies associated with paraproteins. The di...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.2002.00041.x
更新日期：2002-04-01 00:00:00
abstract：:Networks linking single genes to multiple phenotypic outcomes can be founded on local anatomical interactions as well as on systemic factors like biochemical products. Here we explore the effects of such interactions by investigating the competing spatial demands of brain and masticatory muscle growth within the hyper...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13393
更新日期：2021-01-13 00:00:00
abstract：:We examined the effects of exercise on diaphragm degeneration and cardiomyopathy in dystrophin-deficient mdx mice. Mdx mice (11 months of age) were exercised (swimming) for 2 months to worsen diaphragm degeneration. Control mdx mice were kept sedentary. Morphological evaluation demonstrated increased fibrosis in the d...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12443
更新日期：2016-05-01 00:00:00
abstract：:This study set out to determine the pattern of development and distribution of the interstitial cells of Cajal (ICC) in the intestinal tract of the equine fetus and neonate. Intestinal tissue samples from 12 naturally aborted equine fetuses and three euthanized neonates were collected and fixed in formalin prior to ap...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.0021-8782.2004.00315.x
更新日期：2004-07-01 00:00:00
abstract：:The venous collateral flow emanating from and around the renal veins was investigated in the human cadaveric fetus. Experimental venous occlusion was performed along several venous pathways under the sphere of influence of the renal veins in 11 fetuses. Radiological techniques were used to investigate renal venous col...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:This study analyses the evaluation of tomographic indicators of tibia structure, assuming that the usual loading pattern shifts from uniaxial compression close to the heel to a combined compression, torsion and bending scheme towards the knee. To this end, pQCT scans were obtained at 5% intervals of the tibia length (...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01201.x
更新日期：2010-04-01 00:00:00
abstract：:In order to investigate further the effects of paralysis on skeletal development in the chick embryo, paralysis was induced at 6 days of incubation by dropping 0.2% solution of decamethonium bromide onto the chorioallantoic membrane and maintaining paralysis through to 20 days of incubation. General effects of paralys...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Although seen frequently during dissections and autopsies, Hyperostosis frontalis interna (HFI) - a morphological pattern of the frontal bone thickening - is often ignored and its nature and development are not yet understood sufficiently. Current macroscopic classification defines four grades/stages of HFI based on t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12506
更新日期：2016-11-01 00:00:00
abstract：:Since their discovery in different human tissues by Zimmermann in 1898, primary cilia have been found in the vast majority of cell types in vertebrates. Primary cilia are considered to be cellular antennae that occupy an ideal cellular location for the interpretation of information both from the environment and from o...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12360
更新日期：2015-10-01 00:00:00
abstract：:The relationship between lung liquid flow and fetal lung development has been studied at the cellular level using ultrastructural techniques. Continuous in utero tracheal ligation and drainage (over a period of 21-28 days) both result in malformations of the developing fetal lamb lung. Ligated lungs are larger, and dr...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-07-01 00:00:00
abstract：:Elastic fibres, which are intimately associated with collagen, a major component of the urethra, have been assumed to contribute to the resting urethral closure pressure. The Miller stain for elastin was used to demonstrate elastic fibres in cryostat sections of guinea pig bladder base, vesicourethral junction (VUJ) a...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19530447.x
更新日期：1999-10-01 00:00:00
abstract：:Retrograde fluorescent transport of Fast Blue (FB) and Diamidino Yellow (DY) was used to study the localisation of neurons that innervate the palpebral conjunctiva and the superior tarsal muscle in the cynomolgous monkey. Labelled cell bodies of sensory neurons including a few double labelled cell bodies were found in...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Literature on the development of the human vagina is abundant; however, contributions concerning the prenatal development of the entire utero-vaginal anlagen (UVA) are rare or carried out in rodents. The primary epithelial characteristics in the adult vagina and uterus are determined during prenatal development and de...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12029
更新日期：2013-04-01 00:00:00
abstract：:Lymphatics in the diaphragm form a specialised system draining fluid from the peritoneal cavity and returning it to the vascular system. Fluid enters subperitoneal lymphatic lacunae, between muscle fibres of the diaphragm, the lacunae being separated from the peritoneal cavity by a barrier comprising, successively, ly...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：
更新日期：1995-06-01 00:00:00
abstract：:Two cases with anomalous fascicles in abductor digiti minimi, noted in the course of dissecting 62 adult postmortem forearms, are described. Both fascicles arose from the flexor retinaculum and the antebrachial fascia; one was inserted into abductor digiti minimi and the other on the proximal phalanx of the 5th finger...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Fascia in the veterinary sciences is drawing attention, such that physiotherapists and animal practitioners are now applying techniques based on the concept of fascia studies in humans. A comprehensive study of fascia is therefore needed in animals to understand the arrangement of the fascial layers in an unguligrade ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13064
更新日期：2019-12-01 00:00:00
abstract：:Developing Xenopus embryos treated during gastrulation with 22 micrograms/l of salmar calcitonin in the ambient water develop into larvae exhibiting a decrease in interocular distance. In view of the hypocalcaemic properties of calcitonin and the importance of calcium ions in cell aggregation, this phenomenon has been...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The fine structure of the elastic cartilage of the pinna has been examined in young rabbits aged from 1 day to 1108 days. Changes associated with growth and development are related not only to age but also to the actual situation in the pinna. In the midline, progressive changes are seen from the tip to the base. The ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:The surface area and volume of 79 human fetuses (body weight 8-4080 g) were estimated by use of a geometric method. It was found that body surface area increased by a factor of about 70, and body volume by a factor of about 400, during the fetal period. Surface area (S, in cm2) was related to body weight (W, in g) and...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：:Light and electron microscopic techniques were employed to study the structure of the ureter of the starling (Sturnus vulgaris). Particular attention was paid to the characterisation of the epithelial cell types. Differences were found in the chemical composition of the mucins found in the ureteric epithelial cells an...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-05-01 00:00:00
abstract：:A series of semen samples from recently fertile men was obtained by masturbation. They were washed and placed in short term culture in BWW medium, and labelled either with tritiated uridine or tritiated tyrosine. Control samples were labelled in the presence of actinomycin D and puromycin respectively, and examined by...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:The canine's olfactory acuity is legendary, but neither its main olfactory system nor its vomeronasal system has been described in much detail. We used immunohistochemistry on paraffin-embedded sections of male and female adult dog vomeronasal organ (VNO) to characterize the expression of proteins known to be expresse...
journal_title：Journal of anatomy
pub_type： 更正并重新发布的文章,杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:Mucins are high molecular weight glycoproteins which constitute the major component of the mucus layer and are produce by many epithelial tissues in vertebrates. Osteopontin (OPN) is an adhesive phosphorylated glycoprotein that is expressed by a broad range of tissues and cells. Although gastric mucins MUC1, MUC5AC, M...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2010.01243.x
更新日期：2010-07-01 00:00:00
abstract：:A study of the attachments of the musculotendinous fibres of the lumbar erector spinae muscle shows that it is made of two parts: a superficial or costal part, and a deep or vertebral part. The superficial part arises by small fleshy slips from the posterior (superficial) surface as well as the rostral and lateral mar...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
