Pleiotropic effects of ribosomal mutations for cycloheximide resistance in a double-resistant homocaryon of Neurospora crassa.

Abstract:

:Pleiotropic effects of two ribosomal mutations for cycloheximide resistance were studied in a double-resistant homocaryon. The results obtained indicated that the combination of the two ribosomal mutations results in: (i) morphological abnormalities which suggest a severe distortion in the extension of cell walls and membranes; (ii) disturbance in the normal 60S-40S subunit ratio; (iii) decreased rate of cell mass production not necessarily associated with inbalance in the 60S-40S ratio; and (iv) cold sensitivity which does not interfere with mycelial mass production.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Vomvoyanni VE,Argyrakis MP

doi

10.1128/JB.139.2.620-624.1979

keywords:

subject

Has Abstract

pub_date

1979-08-01 00:00:00

pages

620-4

issue

2

eissn

0021-9193

issn

1098-5530

journal_volume

139

pub_type

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