Genetic dissection of learning and memory in mice.

abstract：:Temporal mechanisms for processing auditory musical rhythms are well established, in which a perceived beat is beneficial for timing purposes. It is yet unknown whether such beat-based timing would also underlie visual perception of temporally structured, ecological stimuli connected to music: dance. In this study, we...

journal_title：Neural plasticity

authors： Su YH,Salazar-López E

更新日期：2016-01-01 00:00:00

abstract：:Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson's disease (PD). In sporadic PD, the most common age-related neurodegenerative movement disorder, nigrostriatal dopaminergic deficits are responsible for the onset of motor symptoms...

journal_title：Neural plasticity

authors： Longhena F,Faustini G,Missale C,Pizzi M,Spano P,Bellucci A

更新日期：2017-01-01 00:00:00

abstract：:The formation of fear memories is a powerful and highly evolutionary conserved mechanism that serves the behavioral adaptation to environmental threats. Accordingly, classical fear conditioning paradigms have been employed to investigate fundamental molecular processes of memory formation. Evidence suggests that a cir...

journal_title：Neural plasticity

authors： Albrecht A,Stork O

更新日期：2017-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a serious medical and social problem worldwide. Because of the complex pathophysiological mechanisms of TBI, effective pharmacotherapy is still lacking. The microglial cells are resident tissue macrophages located in the brain and have two major polarization states, M1 phenotype and M2 ...

journal_title：Neural plasticity

authors： Xu H,Wang Z,Li J,Wu H,Peng Y,Fan L,Chen J,Gu C,Yan F,Wang L,Chen G

更新日期：2017-01-01 00:00:00

abstract：:When activated, metabotropic glutamate receptors (mGlus) exert long-lasting changes within the glutamatergic synapses. One mechanism is a tonic effect of downstream signal transduction pathways via sustained activation of mGlu itself. Like many other G protein-coupled receptors (GPCRs), mGlu can exist in a constitutiv...

journal_title：Neural plasticity

authors： Chung G,Kim SJ

更新日期：2017-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is one of the most serious public health concerns facing the world. Its characteristic feature is neuroinflammation due to microglial activation. Electroacupuncture is one of the therapies employed to improve the condition of patients with AD, although its mechanism of action is still to be de...

journal_title：Neural plasticity

authors： Li Y,Jiang J,Tang Q,Tian H,Wang S,Wang Z,Liu H,Yang J,Ren J

更新日期：2020-09-04 00:00:00

abstract：:Postural problems play a central role in the motor dysfunction of children with cerebral palsy (CP). Therefore, they spend more time in sitting than in standing to perform vital tasks of daily life. The focus of this article is to describe the pathophysiology of postural control in sitting and outline some implication...

journal_title：Neural plasticity

authors： Carlberg EB,Hadders-Algra M

更新日期：2005-01-01 00:00:00

abstract：:Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons. It has also been shown to acutely induce epileptic seizure behavior in freely moving rats. However, whether CTZ indu...

journal_title：Neural plasticity

authors： Kong S,Cheng Z,Liu J,Wang Y

更新日期：2014-01-01 00:00:00

abstract：:Inhibitors of HMG-CoA reductase (statins), widely used to lower cholesterol in coronary heart and vascular disease, are effective drugs in reducing the risk of stroke and improving its outcome in the long term. After ischemic stroke, cardiac autonomic dysfunction and psychological problems are common complications rel...

journal_title：Neural plasticity

authors： Cho KJ,Cheon SY,Kim GW

更新日期：2015-01-01 00:00:00

abstract：:Major depressive disorder is a severe and complex mental disorder. Impaired neurotransmission and disrupted signalling pathways may influence neuroplasticity, which is involved in the brain dysfunction in depression. Traditional neurobiological theories of depression, such as monoamine hypothesis, cannot fully explain...

journal_title：Neural plasticity

authors： Huang YJ,Lane HY,Lin CH

更新日期：2017-01-01 00:00:00

abstract：:The aim of the present study was to assess the role of action observation treatment (AOT) in the rehabilitation of upper limb motor functions in children with cerebral palsy. We carried out a two-group, parallel randomized controlled trial. Eighteen children (aged 5-11 yr) entered the study: 11 were treated children, ...

journal_title：Neural plasticity

authors： Buccino G,Molinaro A,Ambrosi C,Arisi D,Mascaro L,Pinardi C,Rossi A,Gasparotti R,Fazzi E,Galli J

更新日期：2018-07-04 00:00:00

abstract：:Glaucoma is an irreversible blinding eye disease which produces progressive retinal ganglion cell (RGC) loss. Intraocular pressure (IOP) is currently the only modifiable risk factor, and lowering IOP results in reduced risk of progression of the disorder. The endocannabinoid system (ECS) has attracted considerable att...

journal_title：Neural plasticity

authors： Cairns EA,Baldridge WH,Kelly ME

更新日期：2016-01-01 00:00:00

abstract：:The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell (HC) mechanotransduction and hearing. Cell junctions are indispensable for the establishment of compositionally distinct fluid compartments in the inner ear. Ototoxic drug cisplatin can damage SV ...

journal_title：Neural plasticity

authors： Zhang N,Cai J,Xu L,Wang H,Liu W

更新日期：2020-09-22 00:00:00

abstract：:Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implicated in several diso...

journal_title：Neural plasticity

authors： Villela D,Suemoto CK,Leite R,Pasqualucci CA,Grinberg LT,Pearson P,Rosenberg C

更新日期：2018-06-28 00:00:00

abstract：:Chronic stress can impair hippocampal neurogenesis, increase neuronal apoptosis, and cause depressive-like behaviors. Our previous studies found that Radix Scutellariae (RS) can rescue the stress-induced neuronal injury, but the mechanism is not clear. Here, we continued to investigate the underlying antidepressant me...

journal_title：Neural plasticity

authors： Zhao F,Zhang C,Xiao D,Zhang W,Zhou L,Gu S,Qu R

更新日期：2020-11-13 00:00:00

abstract：:Magnetic resonance imaging (MRI) of the human brain has provided converging evidence that visual deprivation induces regional changes in white matter (WM) microstructure. It remains unclear how these changes modify network connections between brain regions. Here we used diffusion-weighted MRI to relate differences in ...

journal_title：Neural plasticity

authors： Reislev NL,Dyrby TB,Siebner HR,Kupers R,Ptito M

更新日期：2016-01-01 00:00:00

abstract：:Emotionally arousing events are typically better remembered than mundane ones, in part because emotionally relevant aspects of our environment are prioritized in attention. Such biased attentional tuning is itself the result of associative processes through which we learn affective and motivational relevance of cues. ...

journal_title：Neural plasticity

authors： Ehlers MR,Todd RM

更新日期：2017-01-01 00:00:00

abstract：:Two principal component analyses of anxiety were undertaken investigating two strains of mice (ABP/Le and C57BL/6ByJ) in two different experiments, both classical tests for assessing anxiety in rodents. The elevated plus-maze and staircase were used for the first experiment, and a free exploratory paradigm and light-d...

journal_title：Neural plasticity

authors： Clément Y,Joubert C,Kopp C,Lepicard EM,Venault P,Misslin R,Cadot M,Chapouthier G

更新日期：2007-01-01 00:00:00

abstract：:Childhood emotional trauma contributes significantly to certain psychopathologies, such as post-traumatic stress disorder. In experimental animals, however, whether or not early-life stress results in behavioral abnormalities in adult animals still remains controversial. Here, we investigated both short-term and long-...

journal_title：Neural plasticity

authors： Chen LJ,Shen BQ,Liu DD,Li ST

更新日期：2014-01-01 00:00:00

abstract：:Freezing of gait (FoG) is among the most disabling symptoms of Parkinson's disease (PD) patients. Recent studies showed that action observation training (AOT) with repetitive practice of the observed actions represents a strategy to induce longer-lasting effects compared with standard physiotherapy. We investigated wh...

journal_title：Neural plasticity

authors： Pelosin E,Barella R,Bet C,Magioncalda E,Putzolu M,Di Biasio F,Cerulli C,Casaleggio M,Abbruzzese G,Avanzino L

更新日期：2018-05-27 00:00:00

abstract：:Temporary functional deafferentation (TFD) by an anesthetic cream on the stroke-affected forearm was shown to improve sensorimotor abilities of stroke patients. The present study investigated different predictors for sensorimotor improvements during TFD and indicated outcome differences between patients grouped in sub...

journal_title：Neural plasticity

authors： Sens E,Franz M,Preul C,Meissner W,Witte OW,Miltner WHR,Weiss T

更新日期：2018-07-29 00:00:00

abstract：:Neurophysiological and neuroimaging data suggest that the brains of not only children but also adults are reorganized based on sensory inputs and behaviors. Plastic changes in the brain are generally beneficial; however, maladaptive cortical reorganization in the auditory cortex may lead to hearing disorders such as t...

journal_title：Neural plasticity

authors： Okamoto H

更新日期：2018-05-20 00:00:00

abstract：:Little is known about prenatal and perinatal brain injury resulting in subsequent clumsy behavior in children. One candidate motor system is the pyramidal tract. The tract traverses the entire central nervous system and, through direct and indirect connections to the brainstem and spinal cord sensory and motor nuclei,...

journal_title：Neural plasticity

authors： Whishaw IQ,Piecharka DM,Drever FR

更新日期：2003-01-01 00:00:00

abstract：:Chronic shoulder pain (CSP) is the third most common musculoskeletal problem. For maximum treatment effectiveness, most acupuncturists usually choose acupoint in the nonpainful side, to alleviate pain or improve shoulder function. This method is named opposite needling, which means acupuncture points on the right side...

journal_title：Neural plasticity

authors： Yan CQ,Huo JW,Wang X,Zhou P,Zhang YN,Li JL,Kim M,Shao JK,Hu SQ,Wang LQ,Liu CZ

更新日期：2020-04-25 00:00:00

abstract：:Background. Clinically, electroacupuncture (EA) is the most common therapy for aging-related cognitive impairment (CI). However, the underlying pathomechanism remains unidentified. The aims of this study were to observe the effect of EA on cognitive function and explore the potential mechanism by which EA acts on the ...

journal_title：Neural plasticity

authors： Hou Z,Qiu R,Wei Q,Liu Y,Wang M,Mei T,Zhang Y,Song L,Shao X,Shang H,Chen J,Sun Z

更新日期：2020-11-04 00:00:00

abstract：Background:Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective:To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods:In ...

journal_title：Neural plasticity

authors： Gandolfi M,Formaggio E,Geroin C,Storti SF,Boscolo Galazzo I,Bortolami M,Saltuari L,Picelli A,Waldner A,Manganotti P,Smania N

更新日期：2018-03-26 00:00:00

abstract：:Several studies have associated reduced expression of synaptosomal-associated protein of 25 kDa (SNAP-25) with schizophrenia, yet little is known about its role in the illness. In this paper, a forebrain glutamatergic neuron-specific SNAP-25 knockout mouse model was constructed and studied to explore the possible path...

journal_title：Neural plasticity

authors： Yang H,Zhang M,Shi J,Zhou Y,Wan Z,Wang Y,Wan Y,Li J,Wang Z,Fei J

更新日期：2017-01-01 00:00:00

abstract：:Increasing research has evidenced that our brain retains a capacity to change in response to experience until late adulthood. This implies that cognitive training can possibly ameliorate age-associated cognitive decline by inducing training-specific neural plastic changes at both neural and behavioral levels. This lon...

journal_title：Neural plasticity

authors： Leung NT,Tam HM,Chu LW,Kwok TC,Chan F,Lam LC,Woo J,Lee TM

更新日期：2015-01-01 00:00:00

abstract：:Stimulating regeneration in the brain has the potential to rescue neuronal networks and counteract progressive pathological changes in Alzheimer's disease (AD). This study investigated whether drugs with different mechanisms of action could enhance neurogenesis and improve cognition in mice receiving human neural stem...

journal_title：Neural plasticity

authors： Lilja AM,Malmsten L,Röjdner J,Voytenko L,Verkhratsky A,Ögren SO,Nordberg A,Marutle A

更新日期：2015-01-01 00:00:00

abstract：:Dichoptic movie viewing has been shown to significantly improve visual acuity in amblyopia in children. Moreover, short-term occlusion of the amblyopic eye can transiently increase its contribution to binocular fusion in adults. In this study, we first asked whether dichoptic movie viewing could improve the visual fun...

journal_title：Neural plasticity

authors： Sauvan L,Stolowy N,Denis D,Matonti F,Chavane F,Hess RF,Reynaud A

更新日期：2019-08-28 00:00:00