Abstract:
:Somatostatin receptors (sst) mediate the numerous physiological actions (e.g., aspects of growth, development, and metabolism) of the somatostatin family of peptides. In this study, we used rainbow trout (Oncorhynchus mykiss) to establish the pattern of sst subtype 1A, 1B, and 2 mRNA expression in selected tissues (optic tectum of brain, endocrine pancreas, and liver) and to evaluate nutritional regulation of sst expression. Quantitative real-time reverse transcription-PCR, sensitive to less than 100 copies, revealed that sst1s and sst2 was differentially expressed, both in terms of distribution among the tissues of study and in terms of relative abundance within a particular tissue. Under normal physiological (fed) conditions, sst1B levels were two times greater than those of sst1A in all tissues examined and levels of sst2 were 2-5 times greater those of sst1B, except in optic tectum, in which sst1B and sst2 mRNA levels appeared equal. Nutritional state modulated the pattern of sst1 and sst2 mRNAs expression. Fasting for 2 or 6 weeks reduced the expression of sst mRNAs in optic tectum; whereas, fasting increased the expression of sst mRNAs in both pancreas and liver. Re-feeding animals for 2 weeks following a 4-week fast restored mRNA levels to near those in tissues from animals which were fed continuously. These findings indicate that the pattern of sst expression in optic tectum, pancreas, and liver is regulated by nutritional state.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Slagter BJ,Kittilson JD,Sheridan MAdoi
10.1016/j.ygcen.2004.09.008keywords:
subject
Has Abstractpub_date
2004-12-01 00:00:00pages
236-44issue
3eissn
0016-6480issn
1095-6840pii
S0016-6480(04)00254-0journal_volume
139pub_type
杂志文章abstract::Intraperitoneal injection of CaCl2 in intact, sham-stanniectomized, and stanniectomized American eels, Anguilla rostrata (LeSueur), resulted in a rapid elevation of plasma calcium level which was more marked and of longer duration in the stanniectomized eels. The same treatment reduced whole body calcium influx (JinCa...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(91)90321-v
更新日期:1991-06-01 00:00:00
abstract::Aromatase is the key enzyme for estrogen biosynthesis and is encoded by Cyp19 gene. Placental cotyledons are the main site of Cyp19 gene expression during pregnancy. The present study was aimed to investigate if DNA methylation and thus epigenetic mechanisms play a potential role in stage-specific regulation of Cyp19 ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2010.07.012
更新日期:2010-11-01 00:00:00
abstract::Chickens were used as a model to further analyze the efficacy and specificity of L-692,429, a novel nonpeptidyl mimic of growth hormone (GH)-releasing peptide-6 (GHRP-6), which is a specific GH-releasing secretagogue in mammals. Actions at the level of the pituitary and the hypothalamus were studied. Pituitaries isola...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1998.7102
更新日期:1998-08-01 00:00:00
abstract::Glucocorticoid hormones (GCs) are central mediators of metabolism and the response to challenges. Because circulating GC levels increase in response to challenges, within-population variation in GCs could reflect among-individual variation in condition or experience. At the same time, individual variation in GC regula...
journal_title:General and comparative endocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.ygcen.2020.113611
更新日期:2021-01-01 00:00:00
abstract::Daily variations in circulating melatonin concentrations have been measured at monthly intervals from April to December 1986 in an Antarctic bird, the emperor penguin, Aptenodytes forsteri, maintained under natural conditions. Both duration of the elevated nighttime melatonin levels and amplitude of the day-night rhyt...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(91)90048-b
更新日期:1991-11-01 00:00:00
abstract::Since an extrapancreatic source of insulin has been postulated in the chick embryo, insulin was sought by immunohistochemistry in the embryo before and after development of the pancreas and other tissues. Using for the first time an antiserum specific for chicken insulin, localization of insulin was investigated in wh...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(89)90102-0
更新日期:1989-02-01 00:00:00
abstract::Circadian rhythm is well known to play a pivotal role in reproduction but the presence of a gonadal circadian rhythm is opening a lot of questions about a local regulation of reproduction. In the present study, we first set to identify the key genes driving circadian rhythmicity from the gonadal transcriptome of the s...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2020.113707
更新日期:2020-12-30 00:00:00
abstract::Recently, we reported the cloning of a cDNA fragment from Fundulus heteroclitus liver encoding the open reading frame of type 2 deiodinase (FhD2). We here report the cloning of 14 kb of genomic sequence from F. heteroclitus that includes the previously reported coding region of the F. heteroclitus Dio2 gene (FhDio2), ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/s0016-6480(02)00071-0
更新日期:2002-09-01 00:00:00
abstract::The response of plasma prolactin (PRL) to manipulations of plasma calcium were investigated in coho salmon. Injection of 3.16 mumol EGTA/10 g body weight (to reduce the plasma calcium activity) resulted in significantly higher plasma PRL levels. Lower doses of EGTA (1.06 and 2.13 mumol/10 g body wt) had no effect on p...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(89)90197-4
更新日期:1989-03-01 00:00:00
abstract::Immunohistochemical methods using affinity adsorbed antibodies raised against the three families of calcitonins (CT) were applied to ultimobranchial (UB) cells in situ to investigate the nature of the Chelonian calcitonin molecule and its distribution in the ultimobranchial bodies of the freshwater turtle, Pseudemys s...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(87)90127-4
更新日期:1987-03-01 00:00:00
abstract::In gravid female goldfish held at 10-12 degrees, a single injection of des Gly10,[D-Ala6]luteinizing hormone-releasing hormone ethylamide (LHRH-A), or 2 injections of LHRH-A given 12 hr apart, increased serum gonadotropin (GtH) concentrations, but did not stimulate germinal vesicle migration or ovulation. Injection of...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(83)90155-7
更新日期:1983-10-01 00:00:00
abstract::We have studied the effects of bovine parathyroid hormone (PTH) and salmon calcitonin (CT) on plasma calcium (Ca) and phosphate levels and on renal function in intact and parathyroidectomized (PTX) chickens, using a simple technique that separates urine from feces. In immature males and egg-laying females, the intrave...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(87)90248-6
更新日期:1987-06-01 00:00:00
abstract::Female red-sided garter snakes (Thamnophis sirtalis parietalis) exhibit a complex array of behavioral patterns. Females may mate once, more than once, or not at all in the spring of the year, and a high percentage of females may mate in late summer before returning to winter hibernacula. The role of mating in the indu...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(86)90243-1
更新日期:1986-01-01 00:00:00
abstract::Rainbow trout were confined for 48 hr, during which time water quality either was allowed to deteriorate (resulting in elevated NH3, elevated free CO2, and reduced dissolved O2) or was maintained at preconfinement levels. Fish were removed and blood samples taken at 0, 2, 4, 8, 24, and 48 hr after the onset of confine...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(92)90240-k
更新日期:1992-12-01 00:00:00
abstract::Previous studies have provided evidence that D-Asp plays a role in steroid-mediated reproductive biology in amphibians, reptiles, birds and mammals. To examine the molecular involvement of D-Asp on steroidogenic pathway regulation, we analysed the expression of StAR, P450 aromatase and 5αRed2 mRNAs in Pelophylax escul...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2011.10.006
更新日期:2012-01-01 00:00:00
abstract::The presence and distribution of cholecystokinin (CCK)/gastrin-like immunoreactivity (IR) was examined in the goldfish pituitary. Intense CCK/gastrin-like IR was consistently observed within fibers of the proximal pars distalis (PD), with fewer IR fibers localized in the rostral PD. Within the proximal PD CCK/gastrin-...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1146
更新日期:1993-10-01 00:00:00
abstract::The crab-eating frog Fejervarya cancrivora inhabits mangrove swamps and marshes in Southeast Asia. In the present study, circulating angiotensin II (Ang II), aldosterone (Aldo), arginine vasotocin (AVT), and corticosterone (Cort) concentrations as well as various blood parameters were studied under osmotically stressf...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2013.10.013
更新日期:2014-01-01 00:00:00
abstract::Several lines of evidence suggest reproduction in the ranid frogs is potently regulated by the gonadal steroids, in particular 5alpha-dihydrotestosterone (DHT) and 17beta-estradiol (E(2)), and a non-gonadal steroid, the stress hormone corticosterone (Cort). Little is known about how these steroid hormones act upon the...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2003.07.001
更新日期:2003-12-01 00:00:00
abstract::Early maternal effects in the form of substances accumulated in the egg, such as carotenoids and hormones, can be physiologically relevant for a good development of offspring. It has been found in different species that testosterone (T) can be beneficial to offspring by increasing growth rate, but detrimental by reduc...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2007.12.010
更新日期:2008-04-01 00:00:00
abstract::The Harderian gland of the lizard Podarcis sicula sicula (Raf) contains connective tissue type mast cells whose numbers vary during the year showing two peaks, one in spring the other in winter. No sex differences are found throughout the year. Thermal and photoperiodic manipulations indicate that only temperature inf...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1997.6925
更新日期:1997-09-01 00:00:00
abstract::The possible physiological role of a putative testicular gonadotropin-releasing hormone (GnRH)-like material was studied in the frog, Rana esculenta. We have investigated (a) changes of mitotic index (MI) of primary spermatogonia (SPG) in GnRH agonist (GnRH-Ag)-treated testes in vitro; (b) changes of androgen concentr...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(90)90098-7
更新日期:1990-07-01 00:00:00
abstract::We developed and validated a noninvasive method to quantify fecal estrogens and progestins as a tool for monitoring long-term ovarian activity in free-ranging African elephants. The lag times between iv injection of [(3)H]estradiol and [(14)C]progesterone and peak excretion of radioactivity in urine and feces were app...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1996.0067
更新日期:1996-05-01 00:00:00
abstract::Receptors for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) in turkey cerebral cortex were characterized using two approaches: (1) in vitro radioreceptor binding of [125I]-VIP, and (2) effects of peptides from the PACAP/VIP/secretin family on cyclic AMP formation. T...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2004.03.007
更新日期:2004-06-01 00:00:00
abstract::Dihydrotestosterone (DHT) and 17β-estradiol (E2) are sex hormones that regulate human hair follicle (HF) growth and are produced by peripheral reduction and aromatization of testosterone. However, the expression patterns of DHT and E2 synthesis-related proteins and their receptors in male yak skin during different HF ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2019.113245
更新日期:2020-01-15 00:00:00
abstract::Vasoactive intestinal polypeptide (VIP) is a neuropeptide that has numerous physiological actions and is widely distributed in the body. However, as yet, there is no sequence information about VIP receptors in lower vertebrates. Partial cDNA fragments spanning transmembrane domains 2 to 6 of VIP receptors were isolate...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1996.6818
更新日期:1997-02-01 00:00:00
abstract::During an eight month study of the reproductive cycle in two age groups, and in both sexes, of tench (Tinca tinca L.), it was found that plasma concentrations of the presumptive 'maturation inducing hormone (MIH)' 17,20β-dihydroxypregn-4-en-3-one (17,20β-P) did not reach a peak during the spawning season, but as much ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2011.03.008
更新日期:2011-06-01 00:00:00
abstract::While the role of corticosterone in mediating the response of birds to acute stress is well established, it has recently been proposed that a decrease in prolactin levels following stress may complement corticosterone in redirecting resources away from breeding activities and towards behaviors promoting immediate surv...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2010.03.011
更新日期:2010-08-01 00:00:00
abstract::Naked mole rats seem to be naturally deficient in cholecalciferol yet exhibit net calcium and inorganic phosphorus absorption efficiencies that approach a physiological maximum (i.e., exceed 94%). Oral supplementation with cholecalciferol therefore does not markedly enhance the efficiency of gastrointestinal absorptio...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1019
更新日期:1993-01-01 00:00:00
abstract::This paper describes changes in the content of free steroid hormones e.g. testosterone (T), estradiol-17β (E2), estrone (E1) and estriol (E3) of Mytilus trossulus from the southern Baltic Sea as a function of season, stage of gametogenesis, sex, tissue (gonadal and somatic) and depth. The highest levels of T, E2, E1 a...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2017.12.006
更新日期:2018-04-01 00:00:00
abstract::The role of ovarian hormones in the expression of parental behavior and in the regulation of LH secretion was investigated in incubating commercial meat-type hens. After ovariectomy, incubating hens continued to incubate eggs normally and brooded day-old chicks given to replace eggs, in a manner similar to sham-ovarie...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1996.0013
更新日期:1996-01-01 00:00:00