当前位置： SCI文献检索 > FERTILITY AND STERILITY期刊下所有文献 > Gonadotropin-releasing hormone agonists and the skeleton.

Gonadotropin-releasing hormone agonists and the skeleton.

Abstract：

OBJECTIVE:To review and evaluate published studies that have assessed the effect on the skeleton of treatment with gonadotropin-releasing hormone agonists (GnRH-a). The effects on bone biochemistry and bone density are presented. DATA IDENTIFICATION:Major studies reporting on bone and GnRH-a use were identified through Excerpta Medica and Medline searches. STUDY SELECTION:Those that have reported on GnRH-a treatment in patients where data relating to skeletal metabolism or bone density were obtained. RESULTS:Changes in bone biochemistry during GnRH-a therapy indicate that there is altered skeletal metabolism associated with GnRH-a use. The data on changes in bone density after a 6-month course of GnRH-a therapy generally indicate some bone loss. The magnitude of any detected change in bone density depends on the skeletal site assessed and the method of assessment. No significant bone loss has been documented in cortical bone; any bone loss occurring is usually associated with trabecular bone and is partially or completely reversible on withdrawal of GnRH-a treatment. CONCLUSIONS:A 6-month course of GnRH-a therapy may result in a small reduction in trabecular bone density that is partially or completely reversible on withdrawal of treatment. The magnitude of any persistent residual bone loss is unlikely to be of clinical relevance and the benefits of a single 6-month course of GnRH-a therapy should not be withheld on the basis of a possible effect on bone.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Fogelman I

doi

10.1016/s0015-0282(16)54948-6

keywords:

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

715-24

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)54948-6

journal_volume

57

pub_type

杂志文章,评审

相关文献

FERTILITY AND STERILITY文献大全
  • Placement of a Malecot catheter to enable embryo transfer after radical trachelectomy.

    abstract：OBJECTIVE:To describe the use of a Malecot catheter as a stent after radical trachelectomy (RT). DESIGN:Case report. SETTING:Assisted conception unit at a teaching hospital in the United Kingdom. PATIENT(S):A 36-year-old woman undergoing IVF after her cervix had been excised for cervical carcinoma. Previous attempts...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2004.11.081

    authors： Aust TR,Herod JJ,Gazvani R

    更新日期：2005-06-01 00:00:00

  • Comparison of live-birth defects after luteal-phase ovarian stimulation vs. conventional ovarian stimulation for in vitro fertilization and vitrified embryo transfer cycles.

    abstract：OBJECTIVE:To assess live-birth defects after a luteal-phase ovarian-stimulation regimen (LPS) for in vitro fertilization (IVF) and vitrified embryo transfer (ET) cycles. DESIGN:Retrospective cohort study. SETTING:Tertiary-care academic medical center. PATIENT(S):Infants who were born between January 1, 2013 and May ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2015.02.020

    authors： Chen H,Wang Y,Lyu Q,Ai A,Fu Y,Tian H,Cai R,Hong Q,Chen Q,Shoham Z,Kuang Y

    更新日期：2015-05-01 00:00:00

  • Pituitary gonadotropin inhibition by a highly active analog of luteinizing hormone-releasing hormone.

    abstract：:Chronic treatment with highly active analogs of luteinizing hormone (LH)-releasing hormone (LH-RH) induces "paradoxical" antifertility effects. Intact male rats, a reduction in testosterone production is observed after the administration of [D-Ser(But)6]-LH-RH(1-9)ethylamide (burserelin, Hoe 766), 50 ng/day subcutaneo...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)43461-8

    authors： Sandow J,Von Rechenberg W,Jerzabek G,Stoll W

    更新日期：1978-08-01 00:00:00

  • Nitric oxide is associated with poor embryo quality and pregnancy outcome in in vitro fertilization cycles.

    abstract：OBJECTIVE:To evaluate the association between follicular and serum nitric oxide (NO) levels and embryo development and outcome in IVF. DESIGN:Prospective, case-control study. SETTING:University hospital, tertiary medical center. PATIENT(S):Eighteen patients with tubal or peritoneal factor infertility and 18 female p...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2004.02.097

    authors： Lee TH,Wu MY,Chen MJ,Chao KH,Ho HN,Yang YS

    更新日期：2004-07-01 00:00:00

  • The effect of the new 2010 World Health Organization criteria for semen analyses on male infertility.

    abstract：OBJECTIVE:To quantify the effect of the new 2010 World Health Organization (WHO) semen analysis reference values on reclassifying previous semen analysis parameters and definition of patients with male factor infertility. DESIGN:A multi-institutional retrospective chart review. SETTING:University and private male inf...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2012.07.1130

    authors： Murray KS,James A,McGeady JB,Reed ML,Kuang WW,Nangia AK

    更新日期：2012-12-01 00:00:00

  • Who's keeping count? The need for regulation is a relative matter.

    abstract：:It is important to have an accurate model for calculating limits to sperm donation so as to avoid inadvertent half-sibling mating and help protect the rights and welfare of the donor- inseminated child. The most highly developed model to date cannot be used as there is inadequate regulation of donor insemination among...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2009.01.099

    authors： Sawyer N

    更新日期：2009-12-01 00:00:00

  • Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials.

    abstract：:Pregnancy outcomes and adverse outcomes in infertility trials are reported to varying extents; for example, 35% of clinical trials reported no information on pregnancy loss, only 43% reported adverse events during the preconception treatment period, and only 7% reported any serious adverse events. Incomplete reporting...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2011.02.040

    authors： Dapuzzo L,Seitz FE,Dodson WC,Stetter C,Kunselman AR,Legro RS

    更新日期：2011-06-30 00:00:00

  • A reduction in the number of unwanted pregnancies among female army draftees through a controlled intervention.

    abstract：OBJECTIVE:To assess the possibility of reducing the risk of unwanted pregnancy through a controlled intervention program that was based on a sex education workshop. DESIGN:Educational intervention study. SETTING:Newly drafted women in a central absorption army base in Israel. PATIENT(S):One thousand seven hundred ni...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(97)00252-5

    authors： Malovizky D,Lavi B,Modan B

    更新日期：1997-09-01 00:00:00

  • Why are multiple pregnancy rates and single embryo transfer rates so different globally, and what do we do about it?

    abstract：:In the early years of in vitro fertilization, overall pregnancy rates were low, and it was considered necessary to transfer more than one embryo to increase the chances of pregnancy. It was not until advances in assisted reproductive technologies resulting in increased pregnancy rates that the concept of transferring ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2020.09.003

    authors： Adamson GD,Norman RJ

    更新日期：2020-10-01 00:00:00

  • Spermatogonial proliferation patterns in men with azoospermia of different etiologies.

    abstract：OBJECTIVE:To demonstrate the pattern(s) of spermatogonial proliferation in different spermatogenic disorders. DESIGN:Retrospective case-control study. Teaching hospital. PATIENT(S):Azoospermic men who underwent testicular biopsy for sperm recovery and preparation for intracytoplasmic sperm injection. INTERVENTION(S)...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(03)02161-7

    authors： Bar-Shira Maymon B,Yogev L,Yavetz H,Lifschitz-Mercer B,Schreiber L,Kleiman SE,Botchan A,Hauser R,Paz G

    更新日期：2003-11-01 00:00:00

  • Role of dextran 70 in microtubal surgery.

    abstract：:Pelvic adhesion formation represents a major problem following fallopian tube surgery for infertility. Intraperitoneal dextran may prevent pelvic adhesions. Extensive personal clinical experience (W. H. U.) with intraperitoneal dextran organ-flotation on completion of tubal and ovarian surgery has appeared to limit ad...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)43765-9

    authors： Utian WH,Goldfarb JM,Starks GC

    更新日期：1979-01-01 00:00:00

  • A technique for standardization and quality control of subjective sperm motility assessments in semen analysis.

    abstract：OBJECTIVE:To establish a quality control method to monitor and eventually to standardize the subjective assessment of sperm motility in conventional semen analysis. DESIGN:Quality control study running over 2 years. SETTING:University infertility clinic and andrology laboratory. PATIENT(S):Randomly chosen patients a...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(97)81455-0

    authors： Yeung CH,Cooper TG,Nieschlag E

    更新日期：1997-06-01 00:00:00

  • Nelson's syndrome in pregnancy.

    abstract：:A patient with Nelson's syndrome whose pregnancy was complicated by symptomatic enlargement of an ACTH-producing pituitary tumor was described. Emergency ablative surgery was performed with successful outcomes for both mother and infant. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48932-6

    authors： Surrey ES,Chang RJ

    更新日期：1985-10-01 00:00:00

  • Ovulation induction in women with premature ovarian failure: a prospective, crossover study.

    abstract：:A prospective crossover study comparing ovulation induction techniques in eight women with premature ovarian failure is presented. These patients were treated with FSH rebound techniques using the GnRH-a, LA, alone in one treatment cycle and the same plus menopausal gonadotropins in the other treatment cycle. Two wome...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)54863-8

    authors： Rosen GF,Stone SC,Yee B

    更新日期：1992-02-01 00:00:00

  • Biochemical, metabolic, and vascular mechanisms in menopausal hot flashes.

    abstract：OBJECTIVE:To determine if increases in core body temperature preceding most hot flashes are caused by increased metabolic rate, peripheral vasoconstriction, or central noradrenergic activation. DESIGN:Laboratory physiological study. SETTING:University medical center. PATIENT(S):Fourteen healthy, postmenopausal women...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0015-0282(98)00137-x

    authors： Freedman RR

    更新日期：1998-08-01 00:00:00

  • Inadequate cervical mucus--a cause of "idiopathic" infertility.

    abstract：:The purpose of this study was to investigate and treat a group of patients referred for "idiopathic" infertility in whom no apparent cause for infertility, apart from inadequate cervical mucus, was found. Hormone investigations revealed that these patients could be divided into two groups: those with low sex steroid p...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)42020-0

    authors： Sher G,Katz M

    更新日期：1976-08-01 00:00:00

  • Morphologic and functional studies of immature rat oocyte-cumulus complexes after cryopreservation.

    abstract：:The effects of freezing and thawing (F/T) on functional activity of immature rat oocyte-cumulus complexes (OCC) were studied. The OCC were divided into three groups according to the number of cumulus-cell layers surrounding them. The OCC were then frozen and thawed (F/T), with dimethyl sulfoxide (DMSO) as cryoprotecta...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Pellicer A,Lightman A,Parmer TG,Behrman HR,De Cherney AH

    更新日期：1988-11-01 00:00:00

  • Serum interleukin-8 levels are elevated in patients with ovarian endometrioma.

    abstract：OBJECTIVE:To determine whether serum interleukin (IL)-8 concentration can be measured in patients with ovarian endometrioma and whether this measurement is a useful tool in diagnosing this disease. DESIGN:A controlled clinical study and an in vitro study. SETTING:Department of Obstetrics and Gynecology, Tottori Unive...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2007.07.1355

    authors： Ohata Y,Harada T,Miyakoda H,Taniguchi F,Iwabe T,Terakawa N

    更新日期：2008-10-01 00:00:00

  • An increased initial follicle-stimulating hormone/luteinizing hormone ratio does not affect ovarian responses and the outcomes of in vitro fertilization.

    abstract：:The tenet that a combination of human follicle-stimulating hormone (hFSH)/human menopausal gonadotropin (hMG) improves follicular recruitment was assessed by randomly treating ovulatory women either with hFSH/hMG on days 3 and 4 of the cycle followed by two ampules of hMG daily or with a constant daily dose of 2 ampul...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0015-0282(16)60315-1

    authors： Benadiva CA,Ben-Rafael Z,Blasco L,Tureck R,Mastroianni L Jr,Flickinger GL

    更新日期：1988-11-01 00:00:00

  • Leptin and reproduction: a review.

    abstract：OBJECTIVE:To review recent advances in understanding the role of leptin in the physiology and pathophysiology of reproduction, with a focus on relevant clinical situations. DESIGN:A MEDLINE computer search was performed to identify relevant articles. RESULT(S):Leptin, an adipocyte hormone important in regulating ener...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/s0015-0282(01)03010-2

    authors： Moschos S,Chan JL,Mantzoros CS

    更新日期：2002-03-01 00:00:00

  • Parasitic leiomyoma in the abdominal wall after laparoscopic myomectomy.

    abstract：OBJECTIVE:To report a case of parasitic leiomyoma of the abdominal wall after laparoscopic myomectomy. DESIGN:Case report. SETTING:Large medical center. PATIENT(S):A 31-year-old woman with a newly developed palpable mass in the abdominal wall near the trocar site of a previous laparoscopic myomectomy. INTERVENTION(...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2007.08.068

    authors： Moon HS,Koo JS,Park SH,Park GS,Choi JG,Kim SG

    更新日期：2008-10-01 00:00:00

  • Use of a synthetic peptide adjuvant for the immunization of baboons with denatured and deglycosylated pig zona pellucida glycoproteins.

    abstract：:Baboons were immunized using a synthetic peptide adjuvant with two purified pig zona pellucida glycoproteins. The major zona pellucida glycoprotein (ZPI) was purified by preparative isoelectric focusing, and the 80 K deglycosylated zona pellucida protein (ZPIII) was purified by preparative sodium dodecyl sulfate polya...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)60861-0

    authors： Dunbar BS,Lo C,Powell J,Stevens VC

    更新日期：1989-08-01 00:00:00

  • Semen parameters and hormonal profile in obese fertile and infertile males.

    abstract：OBJECTIVE:To study the changes in semen parameters, gonadotropic and sex hormones, and serum leptin in obese fertile and infertile oligozoospermic men. DESIGN:Prospective. SETTING:University hospital. PATIENT(S):Forty-two obese fertile and 80 obese infertile oligozoospermic men (body mass index [BMI] >30). INTERVEN...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2009.03.085

    authors： Hofny ER,Ali ME,Abdel-Hafez HZ,Kamal Eel-D,Mohamed EE,Abd El-Azeem HG,Mostafa T

    更新日期：2010-07-01 00:00:00

  • High expression of luteinizing hormone receptors messenger RNA by human cumulus granulosa cells is in correlation with decreased fertilization.

    abstract：OBJECTIVE:To elucidate the LH receptor (LHR) expression patterns in human granulosa cells (GCs) from antral to preovulatory stages, and to investigate a correlation to oocyte function. DESIGN:Luteinized preovulatory GCs were obtained from preovulatory follicles aspirated during IVF (≥ 17 mm). The GCs from small- (<10 ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2011.12.027

    authors： Maman E,Yung Y,Kedem A,Yerushalmi GM,Konopnicki S,Cohen B,Dor J,Hourvitz A

    更新日期：2012-03-01 00:00:00

  • Assisted reproductive technology in the United States: 1997 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry.

    abstract：OBJECTIVE:To summarize the procedures and outcomes of assisted reproductive technology (ART) initiated in the United States in 1997. DESIGN:Data were collected electronically by using Society for Assisted Reproductive Technology Clinical Outcome Reporting System software and were submitted to the American Society for ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/s0015-0282(00)01559-4

    authors：

    更新日期：2000-10-01 00:00:00

  • Human gonadotropin therapy. II. Serum estradiol and progesterone patterns during nonconceptual cycles.

    abstract：:Hormone patterns during 113 nonconceptual gonadotropin-induced cycles of 65 infertile anovulatory women were analyzed. All but one women ovulated, i.e., the ovulation rate was 98%. Signs of defective corpus luteum function were observed during 8 cycles, and anovulation occurred in 11 treatment cycles. The duration of ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)47115-3

    authors： Bergquist C,Nillius SJ,Wide L

    更新日期：1983-06-01 00:00:00

  • Improved motility recovery of human spermatozoa after freeze preservation via a new approach.

    abstract：:A new sperm isolation technique was studied in conjunction with the short-term freeze preservation of human spermatozoa. The isolation procedure yielded subpopulations of spermatozoa with very high percentage motility and progressive motility score, and which were virtually free of seminal debris. For 24 semen samples...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)42196-5

    authors： Glaub JC,Mills RN,Katz DF

    更新日期：1976-11-01 00:00:00

  • A prospective randomized comparison of luteal phase versus concurrent follicular phase initiation of gonadotropin-releasing hormone agonist for in vitro fertilization.

    abstract：OBJECTIVE:To compare the effects of gonadotropin-releasing hormone agonist (GnRH-a) initiation either preceding or concurrent with controlled ovarian hyperstimulation (COH) in patients undergoing in vitro fertilization-embryo transfer (IVF-ET). DESIGN:Fifty-five patients were prospectively randomized to receive either...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0015-0282(16)55322-9

    authors： San Roman GA,Surrey ES,Judd HL,Kerin JF

    更新日期：1992-10-01 00:00:00

  • Inhibition of capacitation in the rabbit.

    abstract：:The effectiveness of antiestrogens and progestins in the inhibition of capacitation in the rabbit uterus and oviduct was studied. The agents tested were 8 mg/day nafoxidine HCL (NHCL), 4 mg/day fluoxymesterone (FM), 4 and 20 mg/day clomiphene citrate (CC), 8 mg/day testosterone (T), 8 mg/day dydrogesterone (D) 4 and ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Hamner CE,Wilson LA Jr

    更新日期：1972-03-01 00:00:00

  • The impact of hydrosalpinx on successful pregnancy in tubal factor infertility treated by in vitro fertilization.

    abstract：OBJECTIVE:To determine the impact of hydrosalpinx on pregnancy rates in patients undergoing IVF for infertility caused by tubal disease. DESIGN:Review of the records of all patients who had undergone IVF for tubal factor infertility at our institution between May 1988 and October 1994. SETTING:A university-sponsored,...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(97)80079-9

    authors： Blazar AS,Hogan JW,Seifer DB,Frishman GN,Wheeler CA,Haning RV

    更新日期：1997-03-01 00:00:00