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Intravascular brachytherapy using 90Sr for saphenous vein grafts having diameters ranging from 2.0-5.0 mm.

Abstract：

PURPOSE:Symptomatic coronary artery disease is routinely treated with angioplasty and stenting. Unfortunately, treatment failure in the form of in-stent restenosis (ISR) occurs relatively frequently. Intravascular brachytherapy (IVBT) is a safe and effective method proven to markedly reduce the rate of ISR in native coronary arteries. The commercially available devices for IVBT are not FDA-approved for treatment of saphenous vein grafts (SVG). This article presents calculated dosimetry for treatment of a wide range of SVG, in addition to further evaluating the dose homogeneity for native coronary arteries. METHODS AND MATERIALS:AAPM Task Group 43 and 60 formalisms permitted dose calculations for a wide range of vessel internal diameters (phi) in both native coronary arteries and SVG. Doses were analytically calculated for the Novoste Beta-Cath 5.0 French (F) treatment devices (30, 40, and 60 mm sourcetrains) when employed for the treatment of native vessels with 2.7

journal_name

Brachytherapy

journal_title

Brachytherapy

authors

Mignano JE,Rivard MJ

doi

10.1016/j.brachy.2004.05.004

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

173-8

issue

3

eissn

1538-4721

issn

1873-1449

pii

S1538-4721(04)00066-2

journal_volume

3

pub_type

杂志文章

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