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Efficacy of IVF using frozen donor semen in cases of previously failed DI cycles compared with tubal infertility: a cohort study.

Abstract：

:A cohort follow-up study was designed to compare the efficacy of IVF using frozen donor semen (IVF-D) following previously failed DI cycles (unexplained female infertility) and direct IVF-D treatment because of tubal infertility (control group). The cohort comprised 189 couples initiating IVF-D after previously failed DI cycles (n = 126) or directly (n = 63). Couples were followed until completion (success or drop-out for personal or medical reasons). Live births and drop-out were expressed both as rate per cycle and crude cumulative rate. Characteristics of IVF-D cycles were similar between the two groups. Moreover, overall outcome was also similar in terms of crude cumulative live birth rate (54.0 versus 57.1% for failed DI cycles and tubal infertility groups respectively). This is the first report on crude cumulative live birth rate based on a cohort follow-up study in unexplained previously failed DI cycles and tubal infertility. Previously failed DI cycles did not impair the chances of achieving a successful pregnancy using IVF-D in this series. Slight oocyte dysfunction, which might underlie the failure of DI cycles, might be overcome using IVF-D.

journal_name

Reprod Biomed Online

journal_title

Reproductive biomedicine online

authors

Guerif F,Saussereau MH,Barthelemy C,Couet ML,Gervereau O,Lansac J,Royere D

doi

10.1016/s1472-6483(10)61275-8

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

404-8

issue

4

eissn

1472-6483

issn

1472-6491

pii

S1472-6483(10)61275-8

journal_volume

9

pub_type

杂志文章

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