Protective effect of vilva juice on glycoconjugate levels in experimentally induced constipation in rats.

Abstract:

:Efficacy of vilva, a polyherbal formulation was evaluated in morphine induced constipated rats. Vilva juice, at a dose of 1.5 ml/100 g body wt was given orally for a period of 7 days. Morphine sulfate was injected to induce constipation on 8th day, 45 min before the experiments. Protein bound glycoconjungates were estimated in intestinal tissue. Altered levels of glycoconjugates were maintained at near normalcy when pretreated with vilva juice in morphine induced rats. Histological changes were observed in the colon tissue. The damage to crypts of Liberkunn in constipated rats were found to be reduced in vilva pretreated rats. Vilva, thus, offered significant protection against morphine induced constipation by way of augmenting mucus secretion.

journal_name

Indian J Exp Biol

authors

Padmini R,Sabitha KE,Devi CS

keywords:

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

1024-7

issue

10

eissn

0019-5189

issn

0975-1009

journal_volume

42

pub_type

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